Devlin's Textbook of Biochemistry with Clinical Correlations presents the biochemistry of mammalian cells, relates events at a cellular level to the subsequent physiological processes in the whole animal, and cites examples of human diseases derived from aberrant biochemical processes. The organization and content are tied together to provide students with the complete picture of biochemistry and how it relates to humans. Loaded with new material and chapters and brimming with detailed, full-color illustrations that clearly explain associated concepts, this sixth edition is an indispensable tool for students and professionals in the medical or health sciences. Key Features of the Sixth Edition Over 250 Clinical Correlations highlighting the significance of the biochemistry to clinical conditions and diseases MCAT-Style Questions with annontated answers in every chapter - in a format similar to that used by the National Board of Medical Examiners More than 1,200 high-quality, full-color illustrations A concise appendix reviewing important Organic Chemistry Concepts New to the Sixth Edition: Fully Updated with a significant revision of all chapters and major topics Two new chapters: Fundamentals of Signal Transduction and Cell Cycle, Programmed Cell Death, and Cancer A Glossary that explains important biochemical terms New sections on the Basal Lamina Protein Complex and Molecular Motors

    In Evolution Impossible, Dr. John Ashton uses discoveries in genetics, biochemistry, geology, radiometric dating, and other scientific disciplines to explain why the theory of evolution is a myth. Regardless of your level of scientific education, you will finish this book able to cite 12 reasons why evolution cannot explain the origin of life.

    It provides a wealth of new information- more than twice the content of the previous edition- and practical insight into more than 530 of the most commonly used herbs in the Chinese pharmacopoeia. Drawing from a wide range of sources, both classical and modern, this edition provides unparalleled perspective and detail that goes far beyond what is available elsewhere to the Western practitioner. Herbs are grouped in chapters by function, with expanded summaries and tables for contrast and comparison. Each herb is identified by is pharmaceutical, pinyin, botanical, and family names, as well as Chinese, Japanese, Korean, and English common names. Key characteristics are provided at the beginning of each entry, along with dosage, properties, channels entered, and relevant cautions and contraindications. This provides a quick overview of essential information. Actions and indications are integrated with important combinations that illustrate the range of an herb's functions, with references to appropriate formulas. This presents a more three-dimensional picture of how each herb is actually used. Expanded commentary offers in-depth analysis and places each herb in its clinical context through rich historical references. The mechanisms of action underlying important combinations, and comparisons with similar herbs, provide a broader context for understanding how the herb can be used with optimal effect. A section devoted to nomenclature and preparation describes the most important methods of processing and preparing each herb, and the advantages of each method. It also provides information about other commonly-used names and historical background.

    In The Compatibility Gene, one of our foremost immunologists tells the remarkable history of these genes' discovery and the unlocking of their secrets. Davis shows how the compatibility gene is radically transforming our knowledge of the way our bodies work - and is having profound consequences for medical research and ethics. Looking to the future, he considers the startling possibilities of what these wondrous discoveries might mean for you and me.

    . . a great read,"" and that has been praised as ""a delightful dance through science"" ("New York Times "bestselling author Mark Hyman, M.D.) and as a ""remarkable and insightful book [that] offers you the chance to achieve the best health of your life"" (Mark Liponis, M.D., Medical Director, Canyon Ranch).Written by bestselling author Gene Stone, "The Secrets of People Who Never Get Sick "arose from his desire to discover what might actually prevent him from getting sick himself. This book, the result of that exploration, tells the stories of twenty-five people who each possess a different secret of excellent health--a secret that makes sense and that Stone discovered has a true scientific underpinning. There are food secrets--why to take garlic and vitamin C, eat more probiotics, becomea vegan, drink a tonic of brewer's yeast. Exercise secrets--the benefits of lifting weights, the power of stretching. Environmental secrets--living in a Blue Zone, understanding the value of germs. Emotional secrets--seek out and stay in touch with friends, cultivate your spirituality. Physical secrets--nap more, take cold showers in the morning. And the wisdom that goes back generations: Yes, chicken soup works.The stories make it personal, the research makes it real, and the do-it-yourself information shows how to integrate each secret into your own life, and become the next person who never gets sick.

    Prusiner received a Nobel Prize, the world's most prestigious award for achievement in physiology or medicine. That he was the sole recipient of the award for the year was entirely appropriate, for his struggle to identify the agent responsible for ravaging the brains of animals suffering from scrapie and mad cow disease, and of humans with Creutzfeldt-Jakob disease, had been waged largely alone and in some cases in the face of strenuous disagreement.   In this book, Prusiner tells the remarkable story of his discovery of prions—infectious proteins that replicate and cause disease but surprisingly contain no genetic material—and reveals how superb and meticulous science is actually practiced using talented teams of researchers who persevere. He recounts the frustrations and rewards of years of research and offers fascinating portraits of his peers as they raced to discover the causes of fatal brain diseases. Prusiner’s hypothesis, once considered heresy, now stands as accepted science and the basis for developing diagnoses and eventual cures. He closes with a meditation on the legacy of his discovery: What will it take to cure Alzheimer’s, Parkinson’s, Lou Gehrig’s and other devastating diseases of the brain?

    Second, it proposes that the inhabitants of this subterranean biosphere are not plants or animals as we know them, but heat-loving bacteria that survive on a diet consisting solely of hydrocarbons that is, natural gas and petroleum. And third and perhaps most heretically, the book advances the stunning idea that most hydrocarbons on Earth are not the byproduct of biological debris ("fossil fuels"), but were a common constituent of the materials from which the earth itself was formed some 4.5 billion years ago.The implications are astounding. The theory proposes answers to often-asked questions: Is the deep hot biosphere where life originated, and do Mars and other seemingly barren planets contain deep biospheres? Even more provocatively, is it possible that there is an enormous store of hydrocarbons upwelling from deep within the earth that can provide us with abundant supplies of gas and petroleum?However far-fetched these ideas seem, they are supported by a growing body of evidence, and by the indisputable stature and seriousness Gold brings to any scientific debate. In this book we see a brilliant and boldly original thinker, increasingly a rarity in modern science, as he develops potentially revolutionary ideas about how our world works.

    Everywhere we turn, someone is preaching the “One True Way” to eat for maximum health. Paleo Diet advocates tell us that all foods less than 12,000 years old are the enemy. Low-carb gurus demonize carbs, then there are the low-fat prophets. But they agree on one thing: there is only one true way to eat for maximum health. The first clue that that is a fallacy is the sheer variety of diets advocated. Indeed, while all of these competing views claim to be backed by “science,” a good look at actual nutritional science itself suggests that it is impossible to identify a single best way to eat. Fitzgerald advocates an agnostic, rational approach to eating habits, based on one’s own habits, lifestyle, and genetics/body type. Many professional athletes already practice this “Good Enough” diet, and now we can too and ditch the brainwashing of these diet cults for good.

    The first small cities formed not only the cradle of civilization, but the spawning ground for the earliest viral epidemics, the first opportunity for viruses to find a home in the human herd. This is a story of fear and ignorance, as everything from demons and the wrath of the gods to minority groups have been blamed for epidemics from smallpox to yellow fever to AIDS. It is a story of grief and heartbreak, as hundreds of thousands, sometimes millions, are wiped out in a single year. And it is a story of great bravery and sacrifice, as doctors and nurses put themselves in harm's way to combat yellow fever in Memphis and Ebola in Zaire, and as researchers risk their own lives to test theories of vaccines and the transmission of disease. Now, in Viruses, Plagues, and History, Michael B. A. Oldstone tells all these stories as he illuminates the history of the devastating diseases that have tormented humanity.Oldstone focuses his tale on a few of the most famous viruses humanity has battled, beginning with some we have effectively defeated, such as smallpox, polio, and measles. Nearly 300 million people were killed by smallpox in this century alone -- more than were killed in all the wars of the twentieth century combined. The author presents a vivid account of the long campaign against the virus, the insightful work of Edward Jenner, who created the smallpox vaccine from cowpox virus in 1796, and the monumental efforts of D. A. Henderson and an army of W.H.O. health care workers to finally eradicate smallpox. The smallpox virus remains the only organism that we have deliberately pushed to complete extinction in the wild.Oldstone then describes the fascinating viruses that have captured headlines in more recent years: Ebola and other hemorrhagic fevers, which literally turn their victims' organs to a bloody pulp; the Hantavirus outbreaks in the southwestern United States and elsewhere; mad cow disease, a frightening illness made worse by government mishandling and secrecy; and, of course, AIDS, often called the plague of our time. And he tells us of the many scientists watching and waiting even now for the next great plague, monitoring influenza strains to see whether the deadly variant from 1918 -- a viral strain that killed over 20 million people in 1918-1919, more than twice the military and civilian casualties of the First World War -- will make a comeback.Viruses have enormous power. They have wiped out cities, brought down dynasties, and helped destroy civilizations. But, as Michael Oldstone reveals, scientific research has given us the power to tame many of these viruses as well. Viruses, Plagues, and History shows us the panorama of humanity's long-standing conflict with our unseen viral enemies, from our successes to our continuing struggles. Oldstone's book is a vivid history of a fascinating field, and a highly reliable dispatch from a worker on the frontiers of this ongoing campaign.

    When Dr. Judy Mikovits finished her presentation the room was silent for a moment, then one of the scientists said, �Oh my God!” The resulting investigation would be like no other in science.For Dr. Mikovits, a twenty-year veteran of the National Cancer Institute, this was the midpoint of a five-year journey that would start with the founding of the Whittemore-Peterson Institute for Neuro-Immune Disease at the University of Nevada, Reno, and end with her as a witness for the federal government against her former employer, Harvey Whittemore, for illegal campaign contributions to Senate Majority Leader Harry Reid.On this journey Dr. Mikovits would face the scientific prejudices against CFS, wander into the minefield that is autism, and through it all struggle to maintain her faith in God and the profession to which she had dedicated her life. This is a story for anybody interested in the peril and promise of science at the very highest levels in our country.

    An individual's Decision Tree begins with genomics, where $400 and a test tube of spit provides a peek at how your DNA influences your health. It taps self-monitoring and collaborative health tools, where iPhone applications and next-generation monitoring gadgets can help individuals successfully change their behavior, once and for all. And it turns to new screening techniques that detect diseases like cancer and diabetes far earlier and with far better prospects for our health. Full of thoughtful, groundbreaking reporting on the impact personalized medicine will have on the average patient, The Decision Tree will show you how to take advantage of this new frontier in health care.

    Squirming parasites, bursting pustules, rotting limbs, and cascading diarrhea: it's all depicted here in vivid detail. Sometimes the remedy proved as unbearable as the sickness itself. Whether performing dire dentistry or ice-pick lobotomies, bloodletting or blistering, the medical practitioners of history were ever inventive, if not effective. Disease played a role in shaping human history, too: read how measles and smallpox hastened the decline of the native peoples of the Americas, and how typhus helped to defeat Napoleon. Extraordinary anecdotes abound, such as the cautionary tale of Typhoid Mary and how a cow called Blossom saved the day. Packed with startling medical illustrations, this morbidly fascinating study of all that ails is bound to grip you from page one and leave you reaching for the disinfectant."

    Fascinating... may presage a paradigm shift in medicine." --Kirkus Reviews (starred review)Teeming with information and big ideas... Outstanding."--Booklist (starred review) The origin of asthma, autism, Alzheimer's, allergies, cancer, heart disease, obesity, and even some kinds of depression is now clear. Award-winning researcher on the microbiome, professor Rodney Dietert presents a new paradigm in human biology that has emerged in the midst of the ongoing global epidemic of noncommunicable diseases.The Human Superorganism makes a sweeping, paradigm-shifting argument. It demolishes two fundamental beliefs that have blinkered all medical thinking until very recently: 1) Humans are better off as pure organisms free of foreign microbes; and 2) the human genome is the key to future medical advances. The microorganisms that we have sought to eliminate have been there for centuries supporting our ancestors. They comprise as much as 90 percent of the cells in and on our bodies--a staggering percentage! More than a thousand species of them live inside us, on our skin, and on our very eyelashes. Yet we have now significantly reduced their power and in doing so have sparked an epidemic of noncommunicable diseases--which now account for 63 percent of all human deaths.Ultimately, this book is not just about microbes; it is about a different way to view humans. The story that Dietert tells of where the new biology comes from, how it works, and the ways in which it affects your life is fascinating, authoritative, and revolutionary. Dietert identifies foods that best serve you, the superorganism; not new fad foods but ancient foods that have made sense for millennia. He explains protective measures against unsafe chemicals and drugs. He offers an empowering self-care guide and the blueprint for a revolution in public health. We are not what we have been taught. Each of us is a superorganism. The best path to a healthy life is through recognizing that profound truth.

    The first volume in this annual series of the best writing by Americans, meticulously selected by bestselling author James Gleick, one of the foremost chronicles of scientific social history, debuts with a stellar collection of writers and thinkers.  Many of these cutting-edge essays offer glimpses of new realms of discovery and thought, exploring territory that is unfamiliar to most of us, or finding the unexpected in the midst of the familiar.  Nobel Laureate physicist Steven Weinberg challenges the idea of whether the universe has a designer; Pulitzer Prize winner Natalie Angier reassesses caveman (and-woman) couture; bestselling author and Darwinian theorist Stephen Jay Gould makes a claim for the man whose ideas Darwin discredited; Timothy Ferris proposes a realistic alternative to wrap-speed interseller travel; neurologist and bestselling author Oliver Sacks reminisces about his first loves-chemistry and math.  This diverse, stimulating and accessible collection is required reading for anyone who wants to travel to the frontier of knowledge.

    But we aren’t the first people to abstain from eating for a purpose. This routine was a common part of our spiritual ancestors’ lives for 1,500 years.Jay Richards argues that Christians should recover the fasting lifestyle, not only to improve our bodies, but to bolster our spiritual health as well. In Eat, Fast, Feast, he combines forgotten spiritual wisdom on fasting and feasting with the burgeoning literature on ketogenic diets and fasting for improved physical and mental health. Based on his popular series “Fasting, Body and Soul” in The Stream, Eat, Fast, Feast explores what it means to substitute our hunger for God for our hunger for food, and what both modern science and the ancient monastics can teach us about this practice.Richards argues that our modern diet—heavy in sugar and refined carbohydrates—locks us into a metabolic trap that makes fasting unfruitful and our feasts devoid of meaning. The good news, he reveals, is that we are beginning to resist the tyranny of processed foods, with millions of people pursuing low carb, ketogenic, paleo, and primal diets. This growing body of experts argue that eating natural fat and fasting is not only safe, but far better than how we eat today.Richards provides a 40-day plan which combines a long-term “nutritional ketosis” with spiritual disciplines. The plan can be used any time of the year or be adapted to a penitential season on the Christian calendar, such as Advent or Lent.Synthesizing recent science with ancient wisdom, Eat, Fast, Feast brings together the physical, mental, and spiritual benefits of intermittent fasting to help Christians improve their lives and their health, and bring them closer to God.