But in the inevitable condition of aging and death, the goals of medicine seem too frequently to run counter to the interest of the human spirit. Nursing homes, preoccupied with safety, pin patients into railed beds and wheelchairs. Hospitals isolate the dying, checking for vital signs long after the goals of cure have become moot. Doctors, committed to extending life, continue to carry out devastating procedures that in the end extend suffering.Gawande, a practicing surgeon, addresses his profession's ultimate limitation, arguing that quality of life is the desired goal for patients and families. Gawande offers examples of freer, more socially fulfilling models for assisting the infirm and dependent elderly, and he explores the varieties of hospice care to demonstrate that a person's last weeks or months may be rich and dignified.

    Eight years later, a schoolteacher who lived four miles away gave birth to a boy whose cherubic smile belied the fast growing tumors that soon riddled his face and chest. The doctors predicted he would not reach his first birthday. They were wrong, but that was only one of many surprises that would eventually come to light in Toms River, culminating in 2001 with a record legal settlement believed to top $35 million and an unprecedented government study confirming the existence of a long-suspected cluster of childhood cancer linked to polluted water and air. A detective story rooted in a scientific quest thousands of years old, Toms River is a tale of dumpers at midnight and deceptions in broad daylight, of corporate avarice and government neglect, and of a few brave individuals who would not keep silent.

    Much more commonly, they are linked to sensory deprivation, intoxication, illness, or injury. People with migraines may see shimmering arcs of light or tiny, Lilliputian figures of animals and people. People with failing eyesight, paradoxically, may become immersed in a hallucinatory visual world. Hallucinations can be brought on by a simple fever or even the act of waking or falling asleep, when people have visions ranging from luminous blobs of color to beautifully detailed faces or terrifying ogres. Those who are bereaved may receive comforting “visits” from the departed. In some conditions, hallucinations can lead to religious epiphanies or even the feeling of leaving one’s own body. Humans have always sought such life-changing visions, and for thousands of years have used hallucinogenic compounds to achieve them. As a young doctor in California in the 1960s, Oliver Sacks had both a personal and a professional interest in psychedelics. These, along with his early migraine experiences, launched a lifelong investigation into the varieties of hallucinatory experience. Here, with his usual elegance, curiosity, and compassion, Dr. Sacks weaves together stories of his patients and of his own mind-altering experiences to illuminate what hallucinations tell us about the organization and structure of our brains, how they have influenced every culture’s folklore and art, and why the potential for hallucination is present in us all, a vital part of the human condition.

    While burnout may seem like the default setting for the modern era, in Can’t Even, BuzzFeed culture writer and former academic Anne Helen Petersen argues that burnout is a definitional condition for the millennial generation, born out of distrust in the institutions that have failed us, the unrealistic expectations of the modern workplace, and a sharp uptick in anxiety and hopelessness exacerbated by the constant pressure to “perform” our lives online. The genesis for the book is Petersen’s viral BuzzFeed article on the topic, which has amassed over eight million reads since its publication in January 2019.Can’t Even goes beyond the original article, as Petersen examines how millennials have arrived at this point of burnout (think: unchecked capitalism and changing labor laws) and examines the phenomenon through a variety of lenses—including how burnout affects the way we work, parent, and socialize—describing its resonance in alarming familiarity. Utilizing a combination of sociohistorical framework, original interviews, and detailed analysis, Can’t Even offers a galvanizing, intimate, and ultimately redemptive look at the lives of this much-maligned generation, and will be required reading for both millennials and the parents and employers trying to understand them.

    She takes us by her side down hospital corridors to visit the wards and meet her unforgettable patients.In the neonatal unit, premature babies fight for their lives, hovering at the very edge of survival, like tiny Emmanuel, wrapped up in a sandwich bag. On the cancer wards, the nurses administer chemotherapy and, long after the medicine stops working, something more important--which Watson learns to recognize when her own father is dying of cancer. In the pediatric intensive care unit, the nurses wash the hair of a little girl to remove the smell of smoke from the house fire. The emergency room is overcrowded as ever, with waves of alcohol and drug addicted patients as well as patients like Betty, a widow suffering chest pain, frail and alone. And the stories of the geriatric ward--Gladys and older patients like her--show the plight of the most vulnerable members of our society.

    In her absence, the landscape had been altered beyond recognition, her tribal government swayed by corporate interests, and her community burdened by a surge in violence and addiction. Three years later, when Lissa learned that a young white oil worker, Kristopher "KC" Clarke, had disappeared from his reservation worksite, she became particularly concerned. No one knew where Clarke had gone, and few people were actively looking for him.Yellow Bird traces Lissa's steps as she obsessively hunts for clues to Clarke's disappearance. She navigates two worlds--that of her own tribe, changed by its newfound wealth, and that of the non-Native oilmen, down on their luck, who have come to find work on the heels of the economic recession. Her pursuit of Clarke is also a pursuit of redemption, as Lissa atones for her own crimes and reckons with generations of trauma.

    But to those who collect them, the map trade can be a cutthroat business, inhabited by quirky and sometimes disreputable characters in search of a finite number of extremely rare objects. Once considered a respectable antiquarian map dealer, E. Forbes Smiley spent years doubling as a map thief —until he was finally arrested slipping maps out of books in the Yale University library. The Map Thief delves into the untold history of this fascinating high-stakes criminal and the inside story of the industry that consumed him. Acclaimed reporter Michael Blanding has interviewed all the key players in this stranger-than-fiction story, and shares the fascinating histories of maps that charted the New World, and how they went from being practical instruments to quirky heirlooms to highly coveted objects. Though pieces of the map theft story have been written before, Blanding is the first reporter to explore the story in full—and had the rare privilege of having access to Smiley himself after he’d gone silent in the wake of his crimes. Moreover, although Smiley swears he has admitted to all of the maps he stole, libraries claim he stole hundreds more—and offer intriguing clues to prove it. Now, through a series of exclusive interviews with Smiley and other key individuals, Blanding teases out an astonishing tale of destruction and redemption. The Map Thief interweaves Smiley’s escapades with the stories of the explorers and mapmakers he knew better than anyone. Tracking a series of thefts as brazen as the art heists in Provenance and a subculture as obsessive as the oenophiles in The Billionaire’s Vinegar, Blanding has pieced together an unforgettable story of high-stakes crime.

    In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. In England, cows attack their owners in the milking parlors, while in the American West, thousands of deer starve to death in fields full of grass.What these strange conditions–including fatal familial insomnia, kuru, scrapie, and mad cow disease–share is their cause: prions. Prions are ordinary proteins that sometimes go wrong, resulting in neurological illnesses that are always fatal. Even more mysterious and frightening, prions are almost impossible to destroy because they are not alive and have no DNA–and the diseases they bring are now spreading around the world.In The Family That Couldn’t Sleep, essayist and journalist D. T. Max tells the spellbinding story of the prion’s hidden past and deadly future

    What motivated Manson in his seemingly mindless selection of victims, and what was his hold over the young women who obeyed his orders? Here is the gripping story of this famous and haunting crime. 50 pages of b/w photographs.

    Spanning early celestial navigation to satellite-enabled warfare, Accessory to War is a richly researched and provocative examination of the intersection of science, technology, industry, and power that will introduce Tyson’s millions of fans to yet another dimension of how the universe has shaped our lives and our world.

    Julia Cooke’s intimate storytelling weaves together the real-life stories of a memorable cast of characters, from Lynne Totten, a science major who decided life in a lab was not for her, to Hazel Bowie, one of the relatively few black stewardesses of the era, as they embraced the liberation of their new jet-set life. Cooke brings to life the story of Pan Am stewardesses’ role in the Vietnam War, as the airline added runs from Saigon to Hong Kong for planeloads of weary young soldiers straight from the battlefields, who were off for five days of R&R, and then flown back to war. Finally, with Operation Babylift—the dramatic evacuation of 2,000 children during the fall of Saigon—the book’s special cast of stewardesses unites to play an extraordinary role on the world stage.

    Their father had gone to sea the previous Friday, the boys told their neighbours, and their mother was visiting her family in Liverpool. Over the next ten days Robert and Nattie spent extravagantly, pawning their parents' valuables to fund trips to the theatre and the seaside. But as the sun beat down on the Coombes house, a strange smell began to emanate from the building. When the police were finally called to investigate, the discovery they made sent the press into a frenzy of horror and alarm, and Robert and Nattie were swept up in a criminal trial that echoed the outrageous plots of the 'penny dreadful' novels that Robert loved to read. In The Wicked Boy, Kate Summerscale has uncovered a fascinating true story of murder and morality - it is not just a meticulous examination of a shocking Victorian case, but also a compelling account of its aftermath, and of man's capacity to overcome the past.

    Months later, several health professionals faced criminal allegations that they deliberately injected numerous patients with drugs to hasten their deaths. Five Days at Memorial, the culmination of six years of reporting, unspools the mystery of what happened in those days, bringing the reader into a hospital fighting for its life and into a conversation about the most terrifying form of health care rationing.In a voice at once involving and fair, masterful and intimate, Fink exposes the hidden dilemmas of end-of-life care and reveals just how ill-prepared we are in America for the impact of large-scale disasters—and how we can do better. A remarkable book, engrossing from start to finish, Five Days at Memorial radically transforms your understanding of human nature in crisis.

    For months Kantor and Twohey had been having confidential discussions with top actresses, former Weinstein employees and other sources, learning of disturbing long-buried allegations, some of which had been covered up by onerous legal settlements. The journalists meticulously picked their way through a web of decades-old secret payouts and nondisclosure agreements, pressed some of the most famous women in the world--and some unknown ones--to risk going on the record, and faced down Weinstein, his team of high-priced defenders, and even his private investigators. But nothing could have prepared them for what followed the publication of their Weinstein story. Within days, a veritable Pandora's Box of sexual harassment and abuse was opened, and women who had suffered in silence for generations began coming forward, trusting that the world would understand their stories. Over the next twelve months, hundreds of men from every walk of life and industry would be outed for mistreating their colleagues. But did too much change--or not enough? Those questions plunged the two journalists into a new phase of reporting and some of their most startling findings yet. With superlative detail, insight, and journalistic expertise, Kantor and Twohey take us for the first time into the very heart of this social shift, reliving in real-time what it took to get the story and giving an up-close portrait of the forces that hindered and spurred change. They describe the surprising journeys of those who spoke up--for the sake of other women, for future generations, and for themselves--and so changed us all.

    With more than one in every five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide. If we are not victims ourselves, we all know someone struggling with the merciless compulsion to alter their experience by changing how their brain functions.Drawing on years of research--as well as personal experience as a recovered addict--researcher and professor Judy Grisel has reached a fundamental conclusion: for the addict, there will never be enough drugs. The brain's capacity to learn and adapt is seemingly infinite, allowing it to counteract any regular disruption, including that caused by drugs. What begins as a normal state punctuated by periods of being high transforms over time into a state of desperate craving that is only temporarily subdued by a fix, explaining why addicts are unable to live either with or without their drug. One by one, Grisel shows how different drugs act on the brain, the kind of experiential effects they generate, and the specific reasons why each is so hard to kick.Grisel's insights lead to a better understanding of the brain's critical contributions to addictive behavior, and will help inform a more rational, coherent, and compassionate response to the epidemic in our homes and communities.