We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

    With great compassion and erudition, Gabor Maté demystifies medical science and, as he did in Scattered Minds, invites us all to be our own health advocates.

    Today, says Dale Purves, the dominant research agenda may have taken us as far as it can--and neuroscientists may be approaching a paradigm shift. In this highly personal book, Purves reveals how we got to this point and offers his notion of where neuroscience may be headed next. Purves guides you through a half-century of the most influential ideas in neuroscience and introduces the extraordinary scientists and physicians who created and tested them. Purves offers a critical assessment of the paths that neuroscience research has taken, their successes and their limitations, and then introduces an alternative approach for thinking about brains. Building on new research on visual perception, he shows why common ideas about brain networks can't be right and uncovers the factors that determine our subjective experience. The resulting insights offer a deeper understanding of what it means to be human. - Why we need a better conception of what brains are trying to do and how they do it Approaches to understanding the brain over the past several decades may be at an impasse - The surprising lessons that can be learned from what we see How complex neural processes owe more to trial-and-error experience than to logical principles - Brains--and the people who think about them Meet some of the extraordinary individuals who've shaped neuroscience - The -ghost in the machine- problem The ideas presented further undermine the concept of free will

    Rick Strassman conducted US DEA-approved clinical research at the University of New Mexico in which he injected 60 volunteers with DMT, one of the most powerful psychedelics known. His detailed account of those sessions is an inquiry into the nature of the human mind and the therapeutic potential of psychedelics. DMT, a plant-derived chemical that is also manufactured by the human brain, consistently produced near-death and mystical experiences. Many volunteers reported convincing encounters with intelligent nonhuman presences, especially "aliens." Nearly all felt that the sessions were among the most profound experiences of their lives.Strassman's research connects DMT with the pineal gland, considered by Hindus to be the site of the seventh chakra and by René Descartes to be the seat of the soul. DMT: The Spirit Molecule makes the case that DMT, naturally released by the pineal gland, facilitates the soul's movement in and out of the body and is an integral part of the birth and death experiences, as well as the highest states of meditation and even sexual transcendence. Strassman also believes that alien abduction experiences are brought on by accidental releases of DMT. If used wisely, DMT could trigger a period of remarkable progress in the scientific exploration of the most mystical regions of the human mind and soul.

    In desperate attempts to cure their patients, physicians injected them with deadly medications, cut holes in their heads, and sterilized them. Years of insufficient funding caused the hospital to decay into a crumbling facility with too few staff, as seen in the 1975 film "One Flew Over the Cuckoo's Nest." Today, after a $360 million makeover, Oregon State Hospital is a modern treatment hospital for the state's civil and forensic mentally ill. In this compelling account of the institution's tragedies and triumphs, author Diane Goeres-Gardner offers an unparalleled look at the very human story of Oregon's historic asylum.

    It provides complete coverage of the new A- and AS-level core specifications being taught from September 2000 onwards and presents concepts in separate, easily accessible double-page spreads. Each spread starts with learning objectives and ends with questions, to check understanding, making the book particularly suitable for self-study.

    Yet, despite the astonishing discoveries of science, we still have only the vaguest idea of how the brain works. In The Idea of the Brain, scientist and historian Matthew Cobb traces how our conception of the brain has evolved over the centuries. Although it might seem to be a story of ever-increasing knowledge of biology, Cobb shows how our ideas about the brain have been shaped by each era's most significant technologies. Today we might think the brain is like a supercomputer. In the past, it has been compared to a telegraph, a telephone exchange, or some kind of hydraulic system. What will we think the brain is like tomorrow, when new technology arises? The result is an essential read for anyone interested in the complex processes that drive science and the forces that have shaped our marvelous brains.

    D.E. Boyer takes us on a fascinating journey from the depths of despair to an amazing quantum world where anything is possible. First, we will learn how to defend ourselves against the chaos in our minds, then we will learn how to rekindle the magic in our hearts. Along the way, the wisdom of Socrates and the myth of Narcissus will transform the way we think and feel. Boyer then shows us how the military teaches their Navy Seal recruits how to handle their thoughts and feelings when someone is trying to kill them, so we can better handle our bosses, spouses, and children when it feels like they are trying to kill us. We will also get a glimpse of death through the eyes of someone who sees people die every day, giving us a much greater appreciation for life. With extremely amusing stories from her own life that touch on her dysfunctional upbringing and traumatizing career as an intensive care nurse, Boyer teaches us how to control our anxiety, boost our fragile self-esteem, and get into a state of flow so that we can spend most of our time loving life, rather than dreading it. She also gives us crucial health and nutrition tips so that we can live longer with our newfound peace and joy, and she shows us how to be more successful at life by being a better friend, spouse, and parent. With every step we take on this path, we'll find ourselves flirting with the hidden power of the mind, a power that often lies just beyond most people's reach. Only by mastering the basics of thinking and feeling can we gain access to this power. Once the door is unlocked, we will enter another dimension, a quantum world where time is irrelevant and the magic of our mind is waiting to be found.

    Elefteriades, one of Men’s Health magazine’s ten best doctors in America, shares moving patient stories and lessons about the human heart. The human heart is a paradox, incredibly strong yet surprisingly fragile. And while stories that reveal its symbolic characteristics abound, there are far fewer that laud its physical capabilities, which are perhaps even more profound. Dr. Elefteriades, one of the most respected cardiac surgeons in America, has treated more than 10,000 patients in his distinguished career. Now, for the first time, he shares fascinating stories of his most memorable patients and cases—patients who have challenged him technically and moved him emotionally, patients who have enriched his life and expanded his horizons while he cared for their hearts. By detailing heart conditions and cardiac reparative procedures with specific yet accessible medical narratives, Dr. Elefteriades encapsulates the beauty, complexity, and majesty of the human heart. But there is far more to this organ—and these stories—than a collection of veins, arteries, and valves. These are stories of courage, miracles, and the bravery of patients (some famous and others not) and their families when facing nearly insurmountable challenges, offering a thought-provoking, informative, and at times heart-wrenching study of the resilience of both the human body and spirit.

    In pursuit of these things, it is undeterred by emotion, fear, or morality. Dopamine is the source of our every urge, that little bit of biology that makes an ambitious business professional sacrifice everything in pursuit of success, or that drives a satisfied spouse to risk it all for the thrill of someone new. Simply put, it is why we seek and succeed; it is why we discover and prosper. Yet, at the same time, it’s why we gamble and squander. From dopamine’s point of view, it’s not the having that matters. It’s getting something—anything—that’s new. From this understanding—the difference between possessing something versus anticipating it—we can understand in a revolutionary new way why we behave as we do in love, business, addiction, politics, religion – and we can even predict those behaviors in ourselves and others. In The Molecule of More: How a Single Chemical in Your Brain Drives Love, Sex, and Creativity—and will Determine the Fate of the Human Race, George Washington University professor and psychiatrist Daniel Z. Lieberman, MD, and Georgetown University lecturer Michael E. Long present a potentially life-changing proposal: Much of human life has an unconsidered component that explains an array of behaviors previously thought to be unrelated, including why winners cheat, why geniuses often suffer with mental illness, why nearly all diets fail, and why the brains of liberals and conservatives really are different.

    What would you see if you removed the skull from the human brain and then slowly worked your way deeper and deeper into the brain, to the level of an individual neuron? With renowned brain researcher Susan Greenfield as your guide, here is your chance to gain a bird's eye view of the human brain—and to learn more about what the brain is, how it works, what happens when one part of the brain is made dysfunctional through stroke or accident, how brain mood-modifying drugs find their targets.In a particularly fascinating chapter, Greenfield surveys for us how a brain is built and then takes us on a tour of the developing brain from the moment of conception.Throughout Greenfield poses the larger questions all readers want to consider, including: At what stage does individuality creep into the developing brain? How does the collection of circuits of neurons give rise not just to an individual brain but an individual consciousness? What might a fetus be conscious of?

    Amy chronicles her harrowing medical journey from the first misdiagnosis to her astonishing recovery after her heart transplant, which is made all the more dramatic by the romantic bedside courtship with her future husband, and her uncompromising desire to become a mother. She presents a patient's perspective of life after a heart transplant with honesty.

    Author Dr. Bruce Lipton is a former medical school professor and research scientist. His experiments, and that of other leading-edge scientists, have examined in great detail the processes by which cells receive information. The implications of this research radically change our understanding of life. It shows that genes and DNA do not control our biology; that instead DNA is controlled by signals from outside the cell, including the energetic messages emanating from our positive and negative thoughts. Dr. Lipton's profoundly hopeful synthesis of the latest and best research in cell biology and quantum physics is being hailed as a major breakthrough showing that our bodies can be changed as we retrain our thinking.

    The book features case discussions, USMLE-style questions, and a USMLE-style practice exam.

    In 1996 Joseph LeDoux's "The Emotional Brain" presented a revelatory examination of the biological bases of our emotions and memories. Now, the world-renowned expert on the brain has produced with a groundbreaking work that tells a more profound story: how the little spaces between the neurons-the brain's synapses--are the channels through which we think, act, imagine, feel, and remember. Synapses encode the essence of personality, enabling each of us to function as a distinctive, integrated individual from moment to moment. Exploring the functioning of memory, the synaptic basis of mental illness and drug addiction, and the mechanism of self-awareness, "Synaptic Self" is a provocative and mind-expanding work that is destined to become a classic.