This volume also provides discussion of Chekhov's plays by some of the twentieth century's great directors, including Konstantin Stanislavsky, Peter Brook, and Mark Rozovsky.A Chronology and Selected Bibliography are also included.

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    Author Charles H. Roth, Jr. carefully presents the theory that is necessary for understanding the fundamental concepts of logic design while not overwhelming students with the mathematics of switching theory. Divided into 20 easy-to-grasp study units, the book covers such fundamental concepts as Boolean algebra, logic gates design, flip-flops, and state machines. By combining flip-flops with networks of logic gates, students will learn to design counters, adders, sequence detectors, and simple digital systems. After covering the basics, this text presents modern design techniques using programmable logic devices and the VHDL hardware description language.

    The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    Rochman takes an authoritative look at the latest hot-button issues in the world of pre- and postnatal testing and tells the stories of women and men struggling to understand the variety of tests and grappling with their results—revelations that are sometimes joyous, sometimes heartbreaking, and often profound.Propelled by human narratives and meticulously reported, The Gene Machine introduces us to scientists working to unlock the secrets of the human genome; gene counselors and spiritual advisers helping parents manage this complex new reality; and, of course, parents themselves, including the author, who glimpse the genetic futures of their children. The Gene Machine is both a scientific road map and a meditation on our power to shape the future, one that gets to the very core of what it means to be human.

    A series of accessible essays reveals what the imaginary worlds of D&D can teach us about ethics, morality, metaphysics and more.Illustrates a wide variety of philosophical concepts and ideas that arise in Dungeons & Dragons gameplay and presents them in an accessible and entertaining manner Reveals how the strategies, tactics, improvisations, and role-play employed by D&D enthusiasts have startling parallels in the real world of philosophy Explores a wide range of philosophical topics, including the nature of free will, the metaphysics of personal identity, the morality of crafting fictions, sex and gender issues in tabletop gameplay, and friendship and collaborative storytelling Provides gamers with deep philosophical insights that can lead to a richer appreciation of D&D and any gaming experience

    Belichick and Pioli have been friends since the 1980s, when Belichick was a young coordinator for the New York Giants. They worked together in Cleveland, New York (Jets) and New England. In 2008, Pioli left for Kansas City to build a Midwestern Patriots model. A year before Pioli left, Dimitroff was the surprising top GM choice of the Falcons, who dreamed of building Patriots South in Atlanta.The culmination of the narrative will be all three men preparing their teams for the lifeblood of the NFL, which is the draft, as all three franchises seek to improve themselves through similar philosophies but perhaps different strategies.

    The first response was no ("A most respectful demurring by me for the excellent writer Charles J. Shields, who offered to be my biographer"). Unwilling to take no for an answer, propelled by a passion for his subject, and already deep into his research, Shields wrote again and this time, to his delight, the answer came back: "O.K." For the next year—a year that ended up being Vonnegut's last—Shields had access to Vonnegut and his letters.And So It Goes is the culmination of five years of research and writing—the first-ever biography of the life of Kurt Vonnegut. Vonnegut resonates with readers of all generations from the baby boomers who grew up with him to high-school and college students who are discovering his work for the first time. Vonnegut's concise collection of personal essays, Man Without a Country, published in 2006, spent fifteen weeks on the New York Times bestseller list and has sold more than 300,000 copies to date. The twenty-first century has seen interest in and scholarship about Vonnegut's works grow even stronger, and this is the first book to examine in full the life of one of the most influential iconoclasts of his time.

    This book explores some of the most historically important and currently debated moral theories about the nature of the right and good. After introducing students in the first chapter to some of the main aims and methods of evaluating a moral theory, the remaining chapters are devoted to an examination of various moral theories including the divine command theory, moral relativism, natural law theory, Kant's moral theory, moral pluralism, virtue ethics, and moral particularism. Providing an introduction to moral theory that explains and critically examines the theories of such classical moral philosophers as Aristotle, Aquinas, Kant, Bentham, Mill, and Ross, this book acquaints students with the work of contemporary moral philosophers.

    At once ironic, humorous, and polemical, this work takes on the "unscientific" form of a mimical-pathetical-dialectical compilation of ideas. Whereas the movement in the earlier pseudonymous writings is away from the aesthetic, the movement in Postscript is away from speculative thought. Kierkegaard intended Postscript to be his concluding work as an author. The subsequent "second authorship" after The Corsair Affair made Postscript the turning point in the entire authorship. Part One of the text volume examines the truth of Christianity as an objective issue, Part Two the subjective issue of what is involved for the individual in becoming a Christian, and the volume ends with an addendum in which Kierkegaard acknowledges and explains his relation to the pseudonymous authors and their writings. The second volume contains the scholarly apparatus, including a key to references and selected entries from Kierkegaard's journals and papers.

    For the first time, William Poundstone reveals the toughest questions used at Microsoft and other Fortune 500 companies -- and supplies the answers. He traces the rise and controversial fall of employer-mandated IQ tests, the peculiar obsessions of Bill Gates (who plays jigsaw puzzles as a competitive sport), the sadistic mind games of Wall Street (which reportedly led one job seeker to smash a forty-third-story window), and the bizarre excesses of today's hiring managers (who may start off your interview with a box of Legos or a game of virtual Russian roulette). How Would You Move Mount Fuji? is an indispensable book for anyone in business. Managers seeking the most talented employees will learn to incorporate puzzle interviews in their search for the top candidates. Job seekers will discover how to tackle even the most brain-busting questions, and gain the advantage that could win the job of a lifetime. And anyone who has ever dreamed of going up against the best minds in business may discover that these puzzles are simply a lot of fun. Why are beer cans tapered on the end, anyway?

    There really are no ultimate authority figures-no one has the secret and there is no place to look up the definitive answers to our questions (not even Google). But, by thinking skeptically and logically, we can combat sloppy reasoning, bad arguments and superstitious thinking. It's difficult, and takes a lot of vigilance, but it's worth the effort.In this tie-in to their incredibly popular "The Skeptics Guide to the Universe" podcast, Steven Novella, MD along with "Skeptical Rogues" Bob Novella, Cara Santa Maria, Jay Novella, and Evan Bernstein will explain the tenets of skeptical thinking and debunk some of the biggest scientific myths, fallacies and conspiracy theories (Anti-vaccines, homeopathy, UFO sightings, etc.) They'll help us try to make sense of what seems like an increasingly crazy world using powerful tools like science and philosophy. THE SKEPTICS' GUIDE TO THE UNIVERSE is your guide through this maze of modern life. It covers essential critical thinking skills, as well as giving insight into how your brain works and how to avoid common pitfalls in thinking. They discuss the difference between science and pseudoscience, how to recognize common science news tropes, how to discuss conspiracy theories with that crazy coworker of yours, and how to apply all of this to everyday life.So, are you ready to join them on an epic scientific quest, one that has taken us from huddling in dark caves to stepping foot on the Moon? (Yes, we really did that.) Like all adventures, this one is foremost a journey of self discovery. The monsters you will slay and challenges you will face are mostly constructs of your own mind. With the SKEPTIC'S GUIDE TO THE UNIVERSE, we can do this together.

    For much of the world, that experience is harrowing: A third of the world is at war; 30 million people in Africa are HIV positive; and more than 150 countries use torture on their own citizens. In 50 Facts That Should Change the World, journalist Jessica Williams explores the realities behind the neutral words of bureaucratic documents. A paperback original.

      The American public school system is in crisis, failing millions of students, producing as many drop-outs as graduates, and threatening our economic future. By 2020, the United States will have 123 million high-skill jobs to fill—and fewer than 50 million Americans qualified to fill them.   Educators, parents, political leaders, business people, and concerned citizens are determined to save our educational system. Waiting for "Superman" offers powerful insights from some of those at the leading edge of educational innovation, including Bill and Melinda Gates, Michelle Rhee, Geoffrey Canada, and more.   Waiting for "Superman" is an inspiring call for reform and includes special chapters that provide resources, ideas, and hands-on suggestions for improving the schools in your own community as well as throughout the nation.   For parents, teachers, and concerned citizens alike, Waiting for "Superman" is an essential guide to the issues, challenges, and opportunities facing America’s schools.

    His four essays on Heidegger include "Philosophy as Science, as Metaphor and as Politics" and "Heidegger, Kundera, and Dickens;" three essays on Derrida (including "Deconstruction and Circumvention" and "Is Derrida a Transcendental Philosopher?") are followed by a discussion of the uses to which Paul de Man and his followers have put certain Derridean ideas. Rorty's concluding essays broaden outward with an essay on "Freud and Moral Deliberation" and essays discussing the social theories and political attitudes of various contemporary figures--Foucault, Lyotard, Habermas, Unger, and Castoriadis.