It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes.This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history – the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our children.Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and future.

    She reveals them to be curious, clever connoisseurs of their world, technologically inventive and ecologically adaptable. Above all, they were successful survivors for more than 300,000 years, during times of massive climatic upheaval.At a time when our species has never faced greater threats, we’re obsessed with what makes us special. But, much of what defines us was also in Neanderthals, and their DNA is still inside us. Planning, co-operation, altruism, craftsmanship, aesthetic sense, imagination... perhaps even a desire for transcendence beyond mortality.It is only by understanding them, that we can truly understand ourselves.

    In what has become one of science's greatest riddles, these large animals vanished in North and South America around the time humans arrived at the end of the last great ice age. Part paleontological adventure and part memoir, Twilight of the Mammoths presents in detail internationally renowned paleoecologist Paul Martin's widely discussed and debated "overkill" hypothesis to explain these mysterious megafauna extinctions. Taking us from Rampart Cave in the Grand Canyon, where he finds himself "chest deep in sloth dung," to other important fossil sites in Arizona and Chile, Martin's engaging book, written for a wide audience, uncovers our rich evolutionary legacy and shows why he has come to believe that the earliest Americans literally hunted these animals to death.As he discusses the discoveries that brought him to this hypothesis, Martin relates many colorful stories and gives a rich overview of the field of paleontology as well as his own fascinating career. He explores the ramifications of the overkill hypothesis for similar extinctions worldwide and examines other explanations for the extinctions, including climate change. Martin's visionary thinking about our missing megafauna offers inspiration and a challenge for today's conservation efforts as he speculates on what we might do to remedy this situation—both in our thinking about what is "natural" and in the natural world itself.

    The threat of the disease kept ships close to home and doomed those vessels that ventured too far from port. The willful ignorance of the royal medical elite, who endorsed ludicrous medical theories based on speculative research while ignoring the life-saving properties of citrus fruit, cost tens of thousands of lives and altered the course of many battles at sea. The cure for scurvy ranks among the greatest of human accomplishments, yet its impact on history has, until now, been largely ignored.From the earliest recorded appearance of the disease in the sixteenth century, to the eighteenth century, where a man had only half a chance of surviving the scourge, to the early nineteenth century, when the British conquered scurvy and successfully blockaded the French and defeated Napoleon, Scurvy is a medical detective story for the ages, the fascinating true story of how James Lind (the surgeon), James Cook (the mariner), and Gilbert Blane (the gentleman) worked separately to eliminate the dreaded affliction.Scurvy is an evocative journey back to the era of wooden ships and sails, when the disease infiltrated every aspect of seafaring life: press gangs "recruit" mariners on the way home from a late night at the pub; a terrible voyage in search of riches ends with a hobbled fleet and half the crew heaved overboard; Cook majestically travels the South Seas but suffers an unimaginable fate. Brimming with tales of ships, sailors, and baffling bureaucracy, Scurvy is a rare mix of compelling history and classic adventure story.

    It develops an understanding of function and evolution into the discussion of anatomy of the various systems.

    Seventy-five years later, in Kitzmiller v. Dover, the ACLU sued to prevent the teaching of an alternative to Darwin’s theory known as "Intelligent Design"—and won. Why did the ACLU turn from defending the free-speech rights of Darwinists to silencing their opponents? Jonathan Wells reveals that, for today’s Darwinists, there may be no other choice: unable to fend off growing challenges from scientists, or to compete with rival theories better adapted to the latest evidence, Darwinism—like Marxism and Freudianism before it—is simply unfit to survive. Wells begins by explaining the basic tenets of Darwinism, and the evidence both for and against it. He reveals, for instance, that the fossil record, which according to Darwin should be teeming with "transitional" fossils showing the development of one species to the next, so far hasn’t produced a single incontestable example. On the other hand, certain well-documented aspects of the fossil record—such as the Cambrian explosion, in which innumerable new species suddenly appeared fully formed—directly contradict Darwin’s theory. Wells also shows how most of the other "evidence" for evolution— including textbook "icons" such as peppered moths, Darwin’s finches, Haeckel’s embryos, and the Tree of Life—has been exaggerated, distorted . . . and even faked. Wells then turns to the theory of intelligent design (ID), the idea that some features of the natural world, such as the internal machinery of cells, are too "irreducibly complex" to have resulted from unguided natural processes alone. In clear-cut layman’s language, he reveals the growing evidence for ID coming out of scientific specialties from microbiology to astrophysics. As Wells explains, religion does play a role in the debate over Darwin—though not in the way evolutionists claim. Wells shows how Darwin reasoned that evolution is true because divine creation "must" be false—a theological assumption oddly out of place in a scientific debate. In other words, Darwinists’ materialistic, atheistic assumptions rule out any theories but their own, and account for their willingness to explain away the evidence—or lack of it. Darwin is an emperor who has no clothes— but it takes a brave man to say so. Jonathan Wells, a microbiologist with two Ph.D.s (from Berkeley and Yale), is that brave man. Most textbooks on evolution are written by Darwinists with an ideological ax to grind. Brave dissidents—qualified scientists—who try to teach or write about intelligent design are silenced and sent to the academic gulag. But fear not: Jonathan Wells is a liberator. He unmasks the truth about Darwinism— why it is wrong and what the real evidence is. He also supplies a revealing list of "Books You’re Not Supposed to Read" (as far as the Darwinists are concerned) and puts at your fingertips all the evidence you need to challenge the most closed-minded Darwinist.

    Yet only now, with the publication of Voyaging, the first of two volumes that will constitute the definitive biography, do we have a truly vivid and comprehensive picture of Darwin as man and as scientist. Drawing upon much new material, supported by an unmatched acquaintance with both the intellectual setting and the voluminous sources, Janet Browne has at last been able to unravel the central enigma of Darwin's career: how did this amiable young gentleman, born into a prosperous provincial English family, grow into a thinker capable of challenging the most basic principles of religion and science? The dramatic story of Voyaging takes us from agonizing personal challenges to the exhilaration of discovery; we see a young, inquisitive Darwin gradually mature, shaping, refining, and finally setting forth the ideas that would at last fall upon the world like a thunderclap in The Origin of Species.

    It isn't surprising then that Koestler should hark back to the opprobrious case of Dr Paul Kammerer, an Austrian biologist whose controversial experiments on the evolutionary process (using among other amphibians the midwife toad, so named for its mating habits) were denounced as fraudulent in 1926 by an American herpetologist, G.K. Noble, in the pages of Nature-- whereupon Kammerer blew his brains out, seemingly confirming the old saw "confession is suicide & suicide is confession." But Koestler's investigation, begun as a study of a scientist who betrayed his commitment to truth, indicates that Kammerer, far from being a laboratory quisling, was probably innocent; a victim of an unknown colleague's machinations to discredit his work & therefore in the larger sense a casualty of the still unresolved war between the nco-Darwinist evolutionists who support the random mutation theory & the heretical Lamarckians who maintain (as did Kammerer's experiments) that acquired characteristics can be transmitted from one generation to another. "I did not start with the intention to rehabilitate Paul Kammerer," says Koestler, "but I ended up with an attempt to do so." In the course of that effort he uses his skill as both inventive fantast & experienced researcher to give the midwife toad case a sense of drama & veracity. Those who found The Double Helix satisfying will enjoy this one too, no matter if they agree with Koestler's conclusions.--Kirkus (edited)

    The story begins in Africa, six to seven million years ago, and encompasses twenty known human species, of which Homo sapiens is the sole survivor. Illustrated with spectacular, three-dimensional scientific reconstructions portrayed in their natural habitat developed by a team of physical anthropologists at the American Museum of Natural History and in concert with experts from around the world, the book is both a guide to extinct human species and an astonishing hominid family photo album.The Last Human presents a comprehensive account of each species with information on its emergence, chronology, geographic range, classification, physiology, lifestyle, habitat, environment, cultural achievements, co-existing species, and possible reasons for extinction. Also included are summaries of fossil discoveries, controversies, and publications. What emerges from the fossil story is a new understanding of Homo sapiens. No longer credible is the notion that our species is the end product of a single lineage, improved over generations by natural selection. Rather, the fossil record shows, we are a species with widely varied precursors, and our family tree is characterized by many branchings and repeated extinctions.Exhibition information:Photographs of most of the reconstructions that appear in this book will be featured in exhibits appearing in the new Hall of Human Origins at the American Museum of Natural History in New York City.  The opening of the Hall is planned for November 2006.

    Just a half century ago, this idea was revolutionary. In April 1953, James Watson and Francis Crick published in Nature their groundbreaking work revealing the double helix structure of DNA. While this discovery received wide attention from both mainstream media and the academic community, it was just one part of the bigger story in this history of molecular biology. By the mid-1950s, the scientific community confirmed that genes were indeed comprised of DNA; they just needed to crack the genetic code—and the race was on. Life’s Greatest Secret is the full and rich history of this challenge and the characters—many of whom were not biologists—whose work contributed to this grand scientific endeavor: mathematician and father of cybernetics Norbert Wiener, physicist Erwin Schrödinger, information theorist Claude Shannon, and biologists Jacques Monod and Marshall Nirenberg.In Life’s Greatest Secret, science historian and zoologist Matthew Cobb shows that the race to crack the genetic code was mostly a matter of craft—individuals or small groups struggling with ideas and concepts as much as they were with facts, trying to find the right experiment to answer the right questions, even if they didn’t know what the questions were, and finding that, even when the most definitive answer served mostly to reveal more ignorance, whether in 1953, with Watson and Crick, or in 1961, when Nirenberg and Matthaei showed how DNA codes for specific amino acids, and again and again thereafter, or in 2000, with the first publication of a human genome. Each discovery was a leap forward in our understanding of the natural world and our place within in, akin to the discoveries of Galileo and Einstein in the realm of physics, or the publication of Darwin’s On the Origin of Species. And each served to show how much bigger the problem was that anyone had previously imagined, a trend that continues, as Cobb shows, even today, whether we are discussing gene regulation, epigenetics, or GMOs.Life’s Greatest Secret is a story of ideas and of experimentation, of ingenuity, insight, and dead-ends, in the hunt to make the greatest discovery of twentieth century biology. Ultimately, though, this is a story of humans exploring what it is that makes us human.

    "Reading The Neanderthal Enigma is like sitting down with a wonderful storyteller in the cave where stories began." -- Jonathan Weiner, author of The Beak of the Finch..

    In Feral Cities, Tristan Donovan digs below the urban gloss to uncover the wild creatures that we share our streets and homes with, and profiles the brave and fascinating people who try to manage them. Along the way readers will meet the wall-eating snails that are invading Miami, the boars that roam Berlin, and the monkey gangs of Cape Town. From feral chickens and carpet-roaming bugs to coyotes hanging out in sandwich shops and birds crashing into skyscrapers, Feral Cities takes readers on a journey through streets and neighborhoods that are far more alive than we often realize, shows how animals are adjusting to urban living, and asks what messages the wildlife in our metropolises have for us.

    The author of The Lives of a Cell and The Medusa and the Snail now raises challenging questions about some of the major issues of our time—AIDS, drug abuse, and aging.With extraordinary perception, author Lewis Thomas discusses topics such as evolutionary biology, the development of language, the therapeutic aspects of medicine, and his love for his profession.

    Ranging from the depths of the ocean to the most arid corners of the land, Caspar Henderson captures the beauty and bizzareness of the many living forms we thought we knew and some we could never have contemplated, inviting us to better imagine the precarious world we inhabit.A witty, vivid blend of cutting edge natural history and meditative reflections, The Book of Barely Imagined Beings is infectious and celebratory about the sheer ingenuity and variety of life.

    Through scrupulous research and vivid first-person reporting, The First Human reveals the perils and the promises of fossil hunting on a grand competitive scale.