With extensive treatment of the heart of epidemiology-from study designs to descriptive epidemiology to quantitative measures-this reader-friendly text is accessible and interesting to a wide range of beginning students in all health-related disciplines. A unique focus is given to real-world applications of epidemiology and the development of skills that students can apply in subsequent course work and in the field. The text is also accompanied by a complete package of instructor and student resources available through a companion Web site.

    But did you know that sham heart surgeries often work just as well as placing real stents? Or that people who think they’re particularly prone to cardiovascular disease are four times as likely to die from cardiac arrest? Such is the power and deadly importance of the expectation effect—how what we think will happen changes what does happen.Melding neuroscience with narrative, science journalist David Robson takes readers on a deep dive into the many life zones the expectation effect permeates. We see how people who believe stress is beneficial become more creative when placed under strain. We see how associating aging with wisdom can add seven plus years to your life. People say seeing is believing but, over and over, Robson proves that the converse is truer: believing is seeing.The Expectation Effect is not woo-woo. You cannot think your way into a pile of money or out of a cancer diagnosis. But just because magical thinking is nonsense doesn’t mean rational magic doesn’t exist. Pointing to accepted psychology and objective physiology, Robson gives us the practical takeaways we need to improve our fitness, productivity, intelligence, and happiness.

    But some tests and therapies are discontinued because they are found to be worse, or at least no better, than what they replaced. Medications like Vioxx and procedures such as vertebroplasty for back pain caused by compression fractures are among the medical "advances" that turned out to be dangerous or useless. What Dr. Vinayak K. Prasad and Dr. Adam S. Cifu call medical reversal happens when doctors start using a medication, procedure, or diagnostic tool without a robust evidence base—and then stop using it when it is found not to help, or even to harm, patients.Drs. Prasad and Cifu narrate fascinating stories from every corner of medicine to explore why medical reversals occur, how they are harmful, and what can be done to avoid them. They explore the difference between medical innovations that improve care and those that only appear to be promising. They also outline a comprehensive plan to reform medical education, research funding and protocols, and the process for approving new drugs that will ensure that more of what gets done in doctors’ offices and hospitals is truly effective.

    What he discovered is a revolution under way—an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease. Deftly excavating and illuminating decades of investigation and analysis, he reveals what we know and don’t know about cancer, showing why a cure remains such a slippery concept. We follow him as he combs through the realms of epidemiology, clinical trials, laboratory experiments, and scientific hypotheses—rooted in every discipline from evolutionary biology to game theory and physics. Cogently extracting fact from a towering canon of myth and hype, he describes tumors that evolve like alien creatures inside the body, paleo-oncologists who uncover petrified tumors clinging to the skeletons of dinosaurs and ancient human ancestors, and the surprising reversals in science’s comprehension of the causes of cancer, with the foods we eat and environmental toxins playing a lesser role. Perhaps most fascinating of all is how cancer borrows natural processes involved in the healing of a wound or the unfolding of a human embryo and turns them, jujitsu-like, against the body. Throughout his pursuit, Johnson clarifies the human experience of cancer with elegiac grace, bearing witness to the punishing gauntlet of consultations, surgeries, targeted therapies, and other treatments. He finds compassion, solace, and community among a vast network of patients and professionals committed to the fight and wrestles to comprehend the cruel randomness cancer metes out in his own family. For anyone whose life has been affected by cancer and has found themselves asking why?, this book provides a new understanding. In good company with the works of Atul Gawande, Siddhartha Mukherjee, and Abraham Verghese, The Cancer Chronicles is endlessly surprising and as radiant in its prose as it is authoritative in its eye-opening science.

    And yet hope has never been more desperately needed.In this urgent book, Jane Goodall, the world's most famous living naturalist and Doug Abrams, internationally-bestselling author, explore--through intimate and thought-provoking dialogue--one of the most sought after and least understood elements of human nature: hope. In The Book of Hope, Jane focuses on her “Four Reasons for Hope”: The Amazing Human Intellect, The Resilience of Nature, The Power of Young People, and The Indomitable Human Spirit.Told through stories from a remarkable career and fascinating research, The Book of Hope touches on vital questions including: How do we stay hopeful when everything seems hopeless? How do we cultivate hope in our children? Filled with engaging dialogue and pictures from Jane’s storied career, The Book of Hope is a deeply personal conversation with one of the most beloved figures in today’s world.And for the first time, Jane tells the story of how she became a messenger of hope: from living through World War II, to her years in Gombe, to realizing she had to leave the forest to travel the world in her role as an advocate for environmental justice. She details the forces that shaped her hopeful worldview, her thoughts on her past, and her revelations about her next--and perhaps final--adventure.There is still hope, and this book will help guide us to it.

    Every day, we break our fast. Hunger explores the range of this primal experience. Sharman Apt Russell, the highly acclaimed author of Anatomy of a Rose and An Obsession with Butterflies, here takes us on a tour of hunger, from eighteen hours without food to thirty-six hours to seven days and beyond. What Russell finds-both in our bodies and in cultures around the world-is extraordinary. It is a biological process that transcends nature to shape the very of fabric of societies. In a fascinating survey of centuries of thought on hunger's unique power, she discovers an ability to adapt to it that is nothing short of miraculous. From the fasting saints of the early Christian church to activists like Mahatma Gandhi, generations have used hunger to make spiritual and political statements. Russell highlights these remarkable cases where hunger can inspire and even heal, but she also addresses the devastating impact of starvation on cultures around the world today. Written with consummate skill, a compassionate heart, and stocked with facts, figures, and fascinating lore, Hunger is an inspiring window on history and the human spirit.

    When first published in 1969, this study was described by the Guardian as …as exciting and readable an account as you could wish." This new edition of the major study on the subject is illustrated by over seventy contemporary black and white illustrations and eight pages of color.A series of natural disasters in the furthest reaches of the Orient during the third of the fourteenth century heralded what was, for the population of Europe, the most devastating period of death and destruction in its history. By the autumn of 1347 the Black Death had reached the shores of the eastern Mediterranean, and the years that followed were to witness a horrifying and apparently relentless epidemic.One third of England's population died between the years 1347 and 1350, and over one thousand villages were deserted, never to be repopulated. In towns and cities the cemeteries were unable to provide space for all the dead, and violence and crime spiraled. Travel became dangerous and interruption of food and other supplies across the country added hunger and deprivation to the problems of people already overwhelmed by the threat of the vilest of deaths. In the countryside the population was halved in places, and as land became plentiful, landowners' profits fell and the government tried in vain to fix labourers' wages and prices, peasant unrest accelerated and the manorial system disintegrated, culminating eventually in the Peasants' Revolt of 1381. Throughout Europe whole societies were disrupted; racial tensions built as a direct result of the plague, and persecution of Jews began in earnest throughout the continent. The social and economic consequences of the period were to reach far into the following century.

    C. J. Peters was on the front lines of our biological battle against “hot” viruses around the world. In the course of that career, he learned countless lessons about our interspecies turf wars with infectious agents. Called in to contain an outbreak of deadly hemorrhagic fever in Bolivia, he confronted the despair of trying to save a colleague who accidentally infected himself with an errant scalpel. Working in Level 4 labs on the Machupo and Ebola viruses, he saw time and again why expensive high-tech biohazard containment equipment is only as safe as the people who use it.   Because of new, emerging viruses, and the return of old, “vanquished” ones for which vaccines do not exist, there remains a very real danger of a new epidemic that could, without proper surveillance and early intervention, spread worldwide virtually overnight. And the possibility of foreign countries or terrorist groups using deadly airborne viruses—the poor man’s nuclear arsenal—looms larger than ever.   High-octane science writing at its best and most revealing, Virus Hunter is a thrilling first-person account of what it is like to be a warrior in the Hot Zone.

    In the 1940s, a bored heiress began creating dollhouse crime scenes depicting murders, suicides, and accidental deaths. Known as the “Mother of Forensic Science,” she revolutionized the field of what was then called legal medicine. In the aftermath of the Manson Family murders, a young woman moved into Sharon Tate’s guesthouse and, over the next two decades, entwined herself with the Tate family. In the mid-nineties, a landscape architect in Brooklyn fell in love with a convicted murderer, the supposed ringleader of the West Memphis Three, through an intense series of letters. After they married, she devoted her life to getting him freed from death row. And in 2015, a teenager deeply involved in the online fandom for the Columbine killers planned a mass shooting of her own.Each woman, Monroe argues, represents and identifies with a particular archetype that provides an entryway into true crime. Through these four cases, she traces the history of American crime through the growth of forensic science, the evolving role of victims, the Satanic Panic, the rise of online detectives, and the long shadow of the Columbine shooting. In a combination of personal narrative, reportage, and a sociological examination of violence and media in the twentieth and twenty-first century, Savage Appetites scrupulously explores empathy, justice, and the persistent appeal of violence.

      Along the way, he reveals the untold story of Hans Asperger, the father of Asperger’s syndrome, whose “little professors” were targeted by the darkest social-engineering experiment in human history; exposes the covert campaign by child psychiatrist Leo Kanner to suppress knowledge of the autism spectrum for fifty years; and casts light on the growing movement of "neurodiversity" activists seeking respect, support, technological innovation, accommodations in the workplace and in education, and the right to self-determination for those with cognitive differences.

    We heeded almost none of them. The result is a pandemic on a scale never before seen in our lifetimes. In this captivating, authoritative, and eye-opening book, science journalist Debora MacKenzie lays out the full story of how and why it happened: the previous viruses that should have prepared us, the shocking public health failures that paved the way, the failure to contain the outbreak, and most importantly, what we must do to prevent future pandemics.Debora MacKenzie has been reporting on emerging diseases for more than three decades, and she draws on that experience to explain how COVID-19 went from a potentially manageable outbreak to a global pandemic. Offering a compelling history of the most significant recent outbreaks, including SARS, MERS, H1N1, Zika, and Ebola, she gives a crash course in Epidemiology 101--how viruses spread and how pandemics end--and outlines the lessons we failed to learn from each past crisis. In vivid detail, she takes us through the arrival and spread of COVID-19, making clear the steps that governments knew they could have taken to prevent or at least prepare for this. Looking forward, MacKenzie makes a bold, optimistic argument: this pandemic might finally galvanize the world to take viruses seriously. Fighting this pandemic and preventing the next one will take political action of all kinds, globally, from governments, the scientific community, and individuals--but it is possible.No one has yet brought together our knowledge of COVID-19 in a comprehensive, informative, and accessible way. But that story can already be told, and Debora MacKenzie's urgent telling is required reading for these times and beyond. It is too early to say where the COVID-19 pandemic will go, but it is past time to talk about what went wrong and how we can do better.

    Gilbert WelchRead Overdiagnosed: Making People Sick in the Pursuit of Health PDF from Beacon Press,H. Gilbert WelchDownload H. Gilbert Welch's PDF E-book Overdiagnosed: Making People Sick in the Pursuit of Health

    From tuberculosis to bird flu and HIV to coronavirus, these infectious diseases share a common origin story: human interaction with animals. Otherwise known as zoonotic diseases for their passage from animals to humans, these pathogens—both pre-existing ones and those newly identified—emerge and re-emerge throughout history, sparking epidemics and pandemics that have resulted in millions of deaths around the world.How did these diseases come about? And what—if anything—can we do to stop them and their fatal march into our countries, our homes, and our bodies? In How to Survive a Pandemic, Dr. Michael Greger, physician and internationally-recognized expert on public health issues, delves into the origins of some of the deadliest pathogens the world has ever seen. Tracing their evolution from the past until today, Dr. Greger spotlights emerging flu and coronaviruses as he examines where these pathogens originated, as well as the underlying conditions and significant human role that have exacerbated their lethal influence to large, and even global, levels.As the world grapples with the devastating impact of the novel coronavirus 2019, Dr. Greger reveals not only what we can do to protect ourselves and our loved ones during a pandemic, but also what human society must rectify to reduce the likelihood of even worse catastrophes in the future.

    In the spring of 2016, as immigration debates rocked the United States, three men in a militia group known as the Crusaders grew aggravated over one Kansas town’s growing Somali community. They decided that complaining about their new neighbors and threatening them directly wasn’t enough. The men plotted to bomb a mosque, aiming to kill hundreds and inspire other attacks against Muslims in America. But they would wait until after the presidential election so that their actions wouldn’t hurt Donald Trump’s chances of winning. An FBI informant befriended the three men, acting as law enforcement’s eyes and ears for eight months. His secretly taped conversations with the militia were pivotal in obstructing their plans and were a linchpin in the resulting trial and convictions for conspiracy to use a weapon of mass destruction.White Hot Hate tells the riveting true story of an averted case of domestic terrorism in one of the most remote towns in the U.S., not far from the infamous town where Capote’s In Cold Blood was set. In the gripping details of this foiled scheme, the chilling, immediate threat of domestic terrorism—and racist anxiety in America— is writ large.

    Lieberman traces the field from its birth as a mystic pseudo-science through its adolescence as a cult of "shrinks" to its late blooming maturity — beginning after World War II — as a science-driven profession that saves lives. With fascinating case studies and portraits of the luminaries of the field — from Sigmund Freud to Eric Kandel — Shrinks is a gripping and illuminating read, and an urgent call-to-arms to dispel the stigma of mental illnesses by treating them as diseases rather than unfortunate states of mind.“A lucid popular history...At once skeptical and triumphalist. It shows just how far psychiatry has come.” —Julia M. Klein, Boston Globe