The story of information begins in a time profoundly unlike our own, when every thought and utterance vanishes as soon as it is born. From the invention of scripts and alphabets to the long-misunderstood talking drums of Africa, Gleick tells the story of information technologies that changed the very nature of human consciousness. He provides portraits of the key figures contributing to the inexorable development of our modern understanding of information: Charles Babbage, the idiosyncratic inventor of the first great mechanical computer; Ada Byron, the brilliant and doomed daughter of the poet, who became the first true programmer; pivotal figures like Samuel Morse and Alan Turing; and Claude Shannon, the creator of information theory itself. And then the information age arrives. Citizens of this world become experts willy-nilly: aficionados of bits and bytes. And we sometimes feel we are drowning, swept by a deluge of signs and signals, news and images, blogs and tweets. The Information is the story of how we got here and where we are heading.

    Medication Madness is a fascinating, frightening, and dramatic look at the role that psychiatric medications have played in fifty cases of suicide, murder, and other violent, criminal, and bizarre behaviors.  As a psychiatrist who believes in holding people responsible for their conduct, the weight of scientific evidence and years of clinical experience eventually convinced Dr. Breggin that psychiatric drugs frequently cause individuals to lose their judgment and their ability to control their emotions and actions. Medication Madness raises and examines the issues surrounding personal responsibility when behavior seems driven by drug-induced adverse reactions and intoxication. Dr. Breggin personally evaluated the cases in the book in his role as a treating psychiatrist, consultant or medical expert.  He interviewed survivors and witnesses, and reviewed extensive medical, occupational, educational and police records. The great majority of individuals lived exemplary lives and committed no criminal or bizarre actions prior to taking the psychiatric medications. Medication Madness reads like a medical thriller, true crime story, and courtroom drama; but it is firmly based in the latest scientific research and dozens of case studies. The lives of the children and adults in these stories, as well as the lives of their families and their victims, were thrown into turmoil and sometimes destroyed by the unanticipated effects of psychiatric drugs.  In some cases our entire society was transformed by the tragic outcomes. Many categories of psychiatric drugs can cause potentially horrendous reactions. Prozac, Paxil, Zoloft, Adderall, Ritalin, Concerta, Xanax, lithium, Zyprexa and other psychiatric medications may spellbind patients into believing they are improved when too often they are becoming worse.  Psychiatric drugs drive some people into psychosis, mania, depression, suicide, agitation, compulsive violence and loss of self-control without the individuals realizing that their medications have deformed their way of thinking and feeling.  This book documents how the FDA, the medical establishment and the pharmaceutical industry have over-sold the value of psychiatric drugs.  It serves as a cautionary tale about our reliance on potentially dangerous psychoactive chemicals to relieve our emotional problems and provides a positive approach to taking personal charge of our lives.

    microbe.” —The Wall Street Journal   Did the Black Death destroy medieval Europe? Did cholera pave the way for modern Manhattan? Did yellow fever help end the slave trade? Remarkably, the answer to all of these questions is yes. Time and again, diseases have impacted the course of human history in surprisingly powerful ways. From influenza to smallpox, from tuberculosis to yellow fever, Bryn Barnard describes the symptoms and paths of the world’s worst diseases—and how the epidemics they spawned have changed history forever.   Filled with fascinating, often gory details about disease and history, Outbreak! is a wonderful combination of science and history.

    Both the book and film were inspired by a series of multimedia presentations on global warming that Gore created and delivers to groups around the world. With this book, Gore, who is one of our environmental heroes—and a leading expert—brings together leading-edge research from top scientists around the world; photographs, charts, and other illustrations; and personal anecdotes and observations to document the fast pace and wide scope of global warming. He presents, with alarming clarity and conclusiveness—and with humor, too—that the fact of global warming is not in question and that its consequences for the world we live in will be disastrous if left unchecked. This riveting new book—written in an accessible, entertaining style—will open the eyes of even the most skeptical.

    Though this tech is still in its infancy, to those on the inside, it is the future. VR will change how we work, how we experience entertainment, how we feel pleasure and other emotions, how we see ourselves, and most importantly, how we relate to each other in the real world. And we will never be the same.Peter Rubin, senior culture editor for Wired and the industry’s go-to authority on the subject, calls it an "intimacy engine." While once we needed another person to feel the sensations of closeness, trust, vulnerability, confidence, and titillation, VR will give us the ability to induce these sensations by ourselves for the first time in human history. This metamorphosis, Rubin argues, is going to have a powerful impact on relationships that will ripple throughout our society and our individual lives.A journey into this uncertain future and a glimpse at the cultural implications and promises of a new reality, Future Presence explores a host of complex questions about what makes us human, what connects us, and what is real. Offering a glimpse into the mind-blowing things happening in universities, labs, and tech companies around the world, Rubin leads readers on an entertaining tour of the weirdest, wildest corners of this fascinating new universe. Describing this book as "half travelogue and half crystal ball", Rubin will:Introduce readers to the creators and consumers of VR technologyShow readers what an experience is like inside the current VR devicesExplain how this technology will upend everything we know about human connection in the futureAt once the incredible, inevitable story of virtual reality’s rise and a look towards the future of our fantasies, Future Presence is a deeply personal examination of what connects us, and an analysis of what relationships, empathy, and sex could look like—sooner than we think.

    Margaret I. Cuomo is inspired to seek out new strategies for waging a smarter war on cancer.This year, about 1.6 million new cases of cancer will be diagnosed and more than 1,500 people will die "per day." We've been asked to accept the disappointing strategy to "manage cancer as a chronic disease." We've allowed pharmaceutical companies to position cancer drugs that extend life by just weeks and may cost $100,000 for a single course of treatment as breakthroughs. Where is the bold leadership that will transform our system from treatment to prevention? Have we forgotten the mission of the National Cancer Act of 1971 to "conquer cancer"?Through an analysis of more than 40 years of medical evidence and interviews with the top cancer researchers, drug company executives, and health policy advisers, Dr. Cuomo reveals intriguing answers to these questions. She shows us how all cancer stakeholders--the pharmaceutical industry, the government, physicians, and concerned Americans--can change the way we view and fight cancer in this country.

    They distill more than 20 years of research and first-hand accounts from the most biodiverse ecosystems on Earth into straightforward principles and guidance for confronting our culture of hyper-novelty.For evolutionary biologists Heather Heying and Bret Weinstein, the cause of our woes is clear: the modern world is out of sync with our ancient brains and bodies. We evolved to live in clans, but today most people don't even know their neighbors' names. Differences between the sexes once served a necessary evolutionary purpose, but today many dismiss the concept of biological sex as offensive. The cognitive dissonance spawned by trying to live in a society we're not built for is killing us.

    From the start, the drug's manufacturer aggressively marketed its patented time-release formula as a breakthrough in the effort to reduce prescription drug abuse. It wasn't long, however, before thrill-seeking teenagers shattered that illusion of safety; by simply crushing an "Oxy," they were able to tap into a high so seductive it would come to dominate their lives. Some patients, seeking relief from pain, also found themselves drawn to the drug's dark side. Pain Killer takes readers on a journey of discovery that begins with the true story of Lindsay, a high-school cheerleader in Virginia who gets hooked on Oxys, and expands outward to explore the critical issues of legitimate pain management, prescription drug abuse, and how the misuse of science by the drug industry threatens the public good. With the fast-rising abuse of prescription drugs by young people ringing alarm bells within government, the how and why behind the OxyContin disaster is a gripping read not only for parents, but also for medical professionals, community leaders, business executives, and all those concerned with this crisis. The dangers described in Pain Killer also reverberate far beyond the threat from a single drug at a particular moment in time. The focus of our government's war on drugs has clearly misled many of us into thinking that only illegal drugs smuggled from beyond our borders can be abused. As Meier tells the dramatic story, some of the most deadly substances are produced and sold legally right here at home.THE EXTRAORDINARY AND TRUE STORY OF OXYCONTIN EQUAL PARTS crime thriller, medical detective story, and business exposé, Pain Killer takes a hard-hitting look at how a powerful drug touted as the salvation for millions triggered a national tragedy. At its inception, the legal narcotic OxyContin was seen as a pharmaceutical dream, a "wonder" drug that would herald a sea change in medical care while reaping vast profits for its maker. It did do that; but it also unleashed a public health crisis that cut a swath of despair and crime through unsuspecting small towns, suburbs, and cities across the country. As reports of OxyContin overdoses made front-page and network news, doctors, narcotics agents, regulators, industry executives, and lawmakers raced in, scrambling to slow the damage. Behind it all stood one of America's wealthiest families, and a drug company whose relentless promotion helped fuel the problem Written by award-winning journalist Barry Meier, whose special report in the New York Times triggered national interest in OxyContin, Pain Killer chronicles the rise of the multibillion dollar pain management industry and lays bare its excesses and abuses.

    But what would it look like to study the whole of history, from the big bang through the present day -- and even into the remote future? How would looking at the full span of time change the way we perceive the universe, the earth, and our very existence?These were the questions David Christian set out to answer when he created the field of "Big History," the most exciting new approach to understanding where we have been, where we are, and where we are going. In Origin Story, Christian takes readers on a wild ride through the entire 13.8 billion years we've come to know as "history." By focusing on defining events (thresholds), major trends, and profound questions about our origins, Christian exposes the hidden threads that tie everything together -- from the creation of the planet to the advent of agriculture, nuclear war, and beyond.With stunning insights into the origin of the universe, the beginning of life, the emergence of humans, and what the future might bring, Origin Story boldly reframes our place in the cosmos.

    A gifted writer, Vertosick shows us that intelligence - the ability to react to the outside world, to change behaviour, to survive - can be found wherever life exists. He demonstrates the keen intelligence of our immune system, how lowly bacteria mutate and outwit antibiotics, and how canny cancer cells elude our natural defences.

    His revelations demystify the strategy behind the company's recent flurry of bold moves, all driven by the pursuit of a business plan unlike any other: to become the indispensable gatekeeper of all the world's information, the one-stop destination for all our information needs. Will Google succeed? And what are the implications of a single company commanding so much information and knowing so much about us? As ambitious as Google's goal is, with 68 percent of all Web searches (and growing), profits that are the envy of the business world, and a surplus of talent, the company is, Stross shows, well along the way to fulfilling its ambition, becoming as dominant a force on the Web as Microsoft became on the PC. Google isn't just a superior search service anymore. In recent years it has launched a dizzying array of new services and advanced into whole new businesses, from the introductions of its controversial Book Search and the irresistible Google Earth, to bidding for a slice of the wireless-phone spectrum and nonchalantly purchasing YouTube for $1.65 billion. Google has also taken direct aim at Microsoft's core business, offering free e-mail and software from word processing to spreadsheets and calendars, pushing a transformative -- and highly disruptive -- concept known as "cloud computing." According to this plan, users will increasingly store all of their data on Google's massive servers -- a network of a million computers that amounts to the world's largest supercomputer, with unlimited capacity to house all the information Google seeks. The more offerings Google adds, and the more ubiquitous a presence it becomes, the more dependent its users become on its services and the more information they contribute to its uni

    But I was getting there. I wanted the world to know that all of this pain I had been feeling…that it was related to my vagina. Thus, Vagina Problems was born. It was a cutesy name. It was my way of taking this pain and saying, “Whatever. I’m here. I have it. It sucks. Let’s talk about it.”In April 2014, Deputy Editorial Director at BuzzFeed Lara Parker opened up to the world in an article on the website: she suffers from endometriosis. And beyond that? She let the whole world know that she wasn’t having any sex, as sex was excruciatingly painful. Less than a year before, she received not only the diagnosis of endometriosis, but also a diagnosis of pelvic floor dysfunction, vulvodynia, vaginismus, and vulvar vestibulitis. Combined, these debilitating conditions have wreaked havoc on her life, causing excruciating pain throughout her body since she was fourteen years old. These are her Vagina Problems. It was five years before Lara learned what was happening to her body. Five years of doctors insisting she just had “bad period cramps,” or implying her pain was psychological. Shamed and stigmatized, Lara fought back against a medical community biased against women and discovered that the ignorance of many doctors about women’s anatomy was damaging more than just her own life. One in ten women have endometriosis and it takes an average of seven years before they receive an accurate diagnosis—or any relief from this incurable illness’ chronic pain. With candid revelations about her vaginal physical therapy, dating as a straight woman without penetrative sex, coping with painful seizures while at the office, diet and wardrobe malfunctions when your vagina hurts all the time, and the depression and anxiety of feeling unloved, Lara tackles it all in Vagina Problems: Endometriosis, Painful Sex, and Other Taboo Topics with courage, wit, love, and a determination to live her best life."

    She takes us by her side down hospital corridors to visit the wards and meet her unforgettable patients.In the neonatal unit, premature babies fight for their lives, hovering at the very edge of survival, like tiny Emmanuel, wrapped up in a sandwich bag. On the cancer wards, the nurses administer chemotherapy and, long after the medicine stops working, something more important--which Watson learns to recognize when her own father is dying of cancer. In the pediatric intensive care unit, the nurses wash the hair of a little girl to remove the smell of smoke from the house fire. The emergency room is overcrowded as ever, with waves of alcohol and drug addicted patients as well as patients like Betty, a widow suffering chest pain, frail and alone. And the stories of the geriatric ward--Gladys and older patients like her--show the plight of the most vulnerable members of our society.

    The word conjures up images of horrific diseases sweeping the globe and killing everyone in their path. But such highly lethal illnesses almost never create pandemics. The reality is deadly serious but far more subtle.In Pandemics: What Everyone Needs to Know�, Peter Doherty, who won the Nobel Prize for his work on how the immune system recognizes virus-infected cells, offers an essential guide to one of the truly life-or-death issues of our age. In concise, question-and-answer format, he explains the causes of pandemics, how they can be counteracted with vaccines and drugs, and how we can better prepare for them in the future. Doherty notes that the term "pandemic" refers not to a disease's severity but to its ability to spread rapidly over a wide geographical area. Extremely lethal pathogens are usually quickly identified and confined. Nevertheless, the rise of high-speed transportation networks and the globalization of trade and travel have radically accelerated the spread of diseases. A traveler from Africa arrived in New York in 1999 carrying the West Nile virus; one mosquito bite later, it was loose in the ecosystem. Doherty explains how the main threat of a pandemic comes from respiratory viruses, such as influenza and SARS, which disseminate with incredible speed through air travel. The climate disruptions of global warming, rising population density, and growing antibiotic resistance all complicate efforts to control pandemics. But Doherty stresses that pandemics can be fought effectively. Often simple health practices, especially in hospitals, can help enormously. And research into the animal reservoirs of pathogens, from SARS in bats to HIV in chimpanzees, show promise for our prevention efforts.Calm, clear, and authoritative, Peter Doherty's Pandemics is one of the most critically important additions to the What Everyone Needs to Know� series.What Everyone Needs to Know� is a registered trademark of Oxford University Press.

    While it's true that we live in an age when we're as obsessed with our bodies as we are with celebrity hairstyles, the reality is that most of us know very little about what chugs, churns, and thumps throughout this miraculous, scientific, and artistic system of anatomy. Yes, you've owned your skin-covered shell for decades, but you probably know more about your cell-phone plan than you do about your own body. When it comes to your longevity and quality of life, understanding your internal systems gives you the power, authority, and ability to live a healthier, younger, and better life. "You: The Owner's Manual" challenges your preconceived notions about how the human body works and ages, then takes you on a tour through all of the highways, back roads, and landmarks inside of you. After taking a quiz that tests your body of knowledge, you'll learn about all of your blood-pumping, food-digesting, and keys-remembering systems and organs.Just as important, you'll get the facts and advice you need to keep your body running long and strong. You'll find out how diseases start and how they affect your body -- as well as advice on how to prevent and beat conditions that threaten your quality of life. Complete with exercise tips, nutritional guidelines, simple lifestyle changes, and alternative approaches, "You: The Owner's Manual" gives you an easy, comprehensive, and life-changing how-to plan for fending off the gremlins of aging. To top it off, you'll also get the great-tasting and calorie-saving Owner's Manual Diet -- a thirty-recipe eating plan that's designedwith only one goal in mind: to help you live a younger life.Welcome to your body. Why don't you come on in and take a look around?