Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients


Ben Goldacre - 2012
    We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

The Vision Revolution: How the Latest Research Overturns Everything We Thought We Knew About Human Vision


Mark Changizi - 2009
    Written for both the casual reader and the science buff hungry for new information, The Vision Revolution is a resource that dispels commonly believed perceptions about sight and offers answers drawn from the field’s most recent research.Changizi focuses on four “why” questions:1. Why do we see in color?2. Why do our eyes face forward?3. Why do we see illusions?4. Why does reading come so naturally to us?Why Do We See in Color?It was commonly believed that color vision evolved to help our primitive ancestors identify ripe fruit. Changizi says we should look closer to home: ourselves. Human color vision evolved to give us greater insights into the mental states and health of other people. People who can see color changes in skin have an advantage over their color-blind counterparts; they can see when people are blushing with embarrassment, purple-faced with exertion or the reddening of rashes. Changizi’s research reveals that the cones in our eyes that allow us to see color are exquisitely designed exactly for seeing color changes in the skin. And it’s no coincidence that the primates with color vision are the ones with bare spots on their faces and other body parts; Changizi shows that the development of color vision in higher primates closely parallels the loss of facial hair, culminating in the near hairlessness and highly developed color vision of humans.Why Do Our Eyes Face Forward?Forward-facing eyes set us apart from most mammals, and there is much dispute as to why we have them. While some speculate that we evolved this feature to give us depth perception available through stereo vision, this type of vision only allows us to see short distances, and we already have other mechanisms that help us to estimate distance. Changizi’s research shows that with two forward-facing eyes, primates and humans have an x-ray ability. Specifically, we’re able to see through the cluttered leaves of the forest environment in which we evolved. This feature helps primates see their targets in a crowded, encroached environment. To see how this works, hold a finger in front of your eyes. You’ll find that you’re able to look “through” it, at what is beyond your finger. One of the most amazing feats of two forward-facing eyes? Our views aren’t blocked by our noses, beaks, etc.Why Do We See Illusions?We evolved to see moving objects, not where they are, but where they are going to be. Without this ability, we couldn’t catch a ball because the brain’s ability to process visual information isn’t fast enough to allow us to put our hands in the right place to intersect for a rapidly approaching baseball. “If our brains simply created a perception of the way the world was at the time light hit the eye, then by the time that perception was elicited—which takes about a tenth of a second for the brain to do—time would have marched on, and the perception would be of the recent past,” Changizi explains. Simply put, illusions occur when our brain is tricked into thinking that a stationary two-dimensional picture has an element that is moving. Our brains project the “moving” element into the future and, as a result, we don’t see what’s on the page, but what our brain thinks will be the case a fraction of a second into the future.Why Does Reading Come So Naturally to Us?We can read faster than we can hear, which is odd, considering that reading is relatively recent, and we’ve evolved to process speech for millions of years. Changizi’s research reveals that language has been carefully designed to tap in to elements of the visual processing center that have evolved for tens of millions of years. Visual signs of all languages are shaped like objects in nature, Changizi says, because we have evolved to see nature easily. “People have noticed letters in nature for some time, and there are artists who have a spent a lot of time photographing Latin letters in natural scenes or on butterfly wings,” Changizi says. “For example, if you look at an upper corner of the room you are in, you will see three contours meeting at a point, making a shape close to that of a ‘Y.’“ The Vision Revolution expands upon how our ancestors found the shapes of Latin letters and delves into how visual signs can have similar shapes even though their inspirations come from very different environments.In addition to these four areas, The Vision Revolution explores other phenomena such as cyclopses, peeking and many more you hadn’t even thought to wonder about. Changizi shows how deeply involved these evolutionary aspects of our vision are in why we see the way we do—and what the future holds for us.“…to understand how culture interacts with vision, one must understand not just the eye’s design, but the actual mechanisms we have evolved,” Changizi says, “for culture can tap in to both the designed responses of our brains and the unintended responses.”The Vision Revolution is a book that finally gives attention to what before has been largely neglected by other works on human vision—a book that looks at the “why.”

Pandora's Lab: Seven Stories of Science Gone Wrong


Paul A. Offit - 2017
    These are today's sins of science—as deplorable as mistaken past ideas about advocating racial purity or using lobotomies as a cure for mental illness. These unwitting errors add up to seven lessons both cautionary and profound, narrated by renowned author and speaker Paul A. Offit. Offit uses these lessons to investigate how we can separate good science from bad, using some of today's most controversial creations—e-cigarettes, GMOs, drug treatments for ADHD—as case studies. For every "Aha!" moment that should have been an "Oh no," this book is an engrossing account of how science has been misused disastrously—and how we can learn to use its power for good.

Written in Bone: Hidden Stories in What We Leave Behind


Sue Black - 2020
    Our stories are marbled into their marrow.Drawing upon her years of research and a wealth of remarkable experience, the world-renowned forensic anthropologist Professor Dame Sue Black takes us on a journey of revelation. From skull to feet, via the face, spine, chest, arms, hands, pelvis and legs, she shows that each part of us has a tale to tell. What we eat, where we go, everything we do leaves a trace, a message that waits patiently for months, years, sometimes centuries, until a forensic anthropologist is called upon to decipher it.Some of this information is easily understood, some holds its secrets tight and needs scientific cajoling to be released. But by carefully piecing together the evidence, the facts of a life can be rebuilt. Limb by limb, case by case – some criminal, some historical, some unaccountably bizarre – Sue Black reconstructs with intimate sensitivity and compassion the hidden stories in what we leave behind.

Germs, Genes, & Civilization: How Epidemics Shaped Who We Are Today


David P. Clark - 2004
    No one can stop him--but he walks away. A miracle? No...dysentery. Microbes saved the Roman Empire. Nearly a millennium later, the microbes of the Black Death ended the Middle Ages, making possible the Renaissance, western democracy, and the scientific revolution. Soon after, microbes ravaged the Americas, paving the way for their European conquest. Again and again, microbes have shaped our health, our genetics, our history, our culture, our politics, even our religion and ethics. This book reveals much that scientists and cultural historians have learned about the pervasive interconnections between infectious microbes and humans. It also considers what our ongoing fundamental relationship with infectious microbes might mean for the future of the human species. The "good side" of history's worst epidemics The surprising debt we owe to killer diseases Where diseases came from... ...and where they may be going Children of pestilence: disease and civilization From Egypt to Mexico, the Romans to Attila the Hun STDs, sexual behavior, and culture How microbes may shape cultural cycles of puritanism and promiscuity

Capture: A Theory of the Mind


David A. Kessler - 2015
    David A Kessler has studied this question with regard to tobacco, food, and drugs. Over the course of these investigations, he identified one underlying mechanism common to a broad range of human suffering. This phenomenon—capture—is the process by which our attention is hijacked and our brains commandeered by forces outside our control.In Capture, Dr. Kessler considers some of the most profound questions we face as human beings: What are the origins of mental afflictions, from everyday unhappiness to addiction and depression—and how are they connected? Where does healing and transcendence fit into this realm of emotional experience?Analyzing an array of insights from psychology, medicine, neuroscience, literature, philosophy, and theology, Dr. Kessler deconstructs centuries of thinking, examining the central role of capture in mental illness and questioning traditional labels that have obscured our understanding of it. With a new basis for understanding the phenomenon of capture, he explores the concept through the emotionally resonant stories of both well-known and un-known people caught in its throes.The closer we can come to fully comprehending the nature of capture, Dr. Kessler argues, the better the chance to alleviate its deleterious effects and successfully change our thoughts and behavior Ultimately, Capture offers insight into how we form thoughts and emotions, manage trauma, and heal. For the first time, we can begin to understand the underpinnings of not only mental illness, but also our everyday worries and anxieties. Capture is an intimate and critical exploration of the most enduring human mystery of all: the mind.

Into the Silent Land: Travels in Neuropsychology


Paul Broks - 2003
    Broks fuses classic cases of neuropsychology with the his own case studies, philosophical debate, and thought provoking riffs and meditations on the nature of neurological impairments and dysfunctions.

Adventures in Memory: Exploring the Science and Secrets of Human Memory


Hilde Østby - 2016
    The authors—two Norwegian sisters, one a neuropsychologist and the other an acclaimed writer—skillfully interweave history, research, and exceptional personal stories, taking readers on a captivating exploration of the evolving science of memory from its humble Renaissance beginnings up to the present day. They interview experts of all stripes, from the world’s top neuroscientists to famous novelists, from taxi drivers to quizmasters, to help explain how memory works, why it sometimes fails, and what we can do to improve it. Filled with cutting-edge research and nimble storytelling, the result is a charming—and memorable—adventure through human memory

Homo Deus: A History of Tomorrow


Yuval Noah Harari - 2015
    This may seem hard to accept, but, as Harari explains in his trademark style—thorough, yet riveting—famine, plague and war have been transformed from incomprehensible and uncontrollable forces of nature into manageable challenges. For the first time ever, more people die from eating too much than from eating too little; more people die from old age than from infectious diseases; and more people commit suicide than are killed by soldiers, terrorists and criminals put together. The average American is a thousand times more likely to die from binging at McDonalds than from being blown up by Al Qaeda.What then will replace famine, plague, and war at the top of the human agenda? As the self-made gods of planet earth, what destinies will we set ourselves, and which quests will we undertake? Homo Deus explores the projects, dreams and nightmares that will shape the twenty-first century—from overcoming death to creating artificial life. It asks the fundamental questions: Where do we go from here? And how will we protect this fragile world from our own destructive powers? This is the next stage of evolution. This is Homo Deus.With the same insight and clarity that made Sapiens an international hit and a New York Times bestseller, Harari maps out our future.

The Social Animal: The Hidden Sources of Love, Character, and Achievement


David Brooks - 2011
    Now, with the intellectual curiosity and emotional wisdom that make his columns among the most read in the nation, Brooks turns to the building blocks of human flourishing in a multilayered, profoundly illuminating work grounded in everyday life.This is the story of how success happens. It is told through the lives of one composite American couple, Harold and Erica—how they grow, push forward, are pulled back, fail, and succeed. Distilling a vast array of information into these two vividly realized characters, Brooks illustrates a fundamental new understanding of human nature. A scientific revolution has occurred—we have learned more about the human brain in the last thirty years than we had in the previous three thousand. The unconscious mind, it turns out, is most of the mind—not a dark, vestigial place but a creative and enchanted one, where most of the brain’s work gets done. This is the realm of emotions, intuitions, biases, longings, genetic predispositions, personality traits, and social norms: the realm where character is formed and where our most important life decisions are made. The natural habitat of The Social Animal. Drawing on a wealth of current research from numerous disciplines, Brooks takes Harold and Erica from infancy to school; from the “odyssey years” that have come to define young adulthood to the high walls of poverty; from the nature of attachment, love, and commitment, to the nature of effective leadership. He reveals the deeply social aspect of our very minds and exposes the bias in modern culture that overemphasizes rationalism, individualism, and IQ. Along the way, he demolishes conventional definitions of success while looking toward a culture based on trust and humility.The Social Animal is a moving and nuanced intellectual adventure, a story of achievement and a defense of progress. Impossible to put down, it is an essential book for our time, one that will have broad social impact and will change the way we see ourselves and the world.

Why We Dream: The Transformative Power of Our Nightly Journey


Alice Robb - 2018
    Finding these forays both puzzling and exhilarating, Robb dug deeper into the science of dreams at an extremely opportune moment: just as researchers began to understand why dreams exist. They aren’t just random events; they have clear purposes. They help us learn and even overcome psychic trauma. Robb draws on fresh and forgotten research, as well as her experience and that of other dream experts, to show why dreams are vital to our emotional and physical health. She explains how we can remember our dreams better—and why we should. She traces the intricate links between dreaming and creativity, and even offers advice on how we can relish the intense adventure of lucid dreaming for ourselves.Why We Dream is a clear-eyed, cutting-edge examination of the meaning and purpose of our nightly visions and a guide to changing our dream lives—and making our waking lives richer, healthier, and happier.

The Uninhabitable Earth: Life After Warming


David Wallace-Wells - 2019
    If your anxiety about global warming is dominated by fears of sea-level rise, you are barely scratching the surface of what terrors are possible. In California, wildfires now rage year-round, destroying thousands of homes. Across the US, "500-year" storms pummel communities month after month, and floods displace tens of millions annually.This is only a preview of the changes to come. And they are coming fast. Without a revolution in how billions of humans conduct their lives, parts of the Earth could become close to uninhabitable, and other parts horrifically inhospitable, as soon as the end of this century.In his travelogue of our near future, David Wallace-Wells brings into stark relief the climate troubles that await--food shortages, refugee emergencies, and other crises that will reshape the globe. But the world will be remade by warming in more profound ways as well, transforming our politics, our culture, our relationship to technology, and our sense of history. It will be all-encompassing, shaping and distorting nearly every aspect of human life as it is lived today.Like An Inconvenient Truth and Silent Spring before it, The Uninhabitable Earth is both a meditation on the devastation we have brought upon ourselves and an impassioned call to action. For just as the world was brought to the brink of catastrophe within the span of a lifetime, the responsibility to avoid it now belongs to a single generation.

When Humans Nearly Vanished: The Catastrophic Explosion of the Toba Volcano


Donald R. Prothero - 2018
    A deep vibration shook the entire island. Jets of steam and ash emanated from the summit, followed by an explosion louder than any sound heard by Homo sapiens since our species evolved on Earth. The eruption of the Toba supervolcano released the energy of a million tons of explosives; seven hundred cubic miles of magma spewed outward in an explosion forty times larger than the largest hydrogen bomb and more than a thousand times as powerful as the Krakatau eruption in 1883. So much ash and debris was injected into the stratosphere that it partially blocked the sun's radiation and caused global temperatures to drop by five to nine degrees. It took a full decade for Earth to recover to its pre-eruption temperatures.When Humans Nearly Vanished presents the controversial argument that the Toba catastrophe nearly wiped out the human race, leaving only about a thousand to ten thousand breeding pairs of humans worldwide. Human genes today show evidence of a "genetic bottleneck," an effect seen when a population of organisms becomes so small that their genetic diversity is greatly reduced. This group of survivors could be the ancestors of all humans alive today. Donald R. Prothero explores the geological and biological evidence supporting the Toba bottleneck theory; reveals how the explosion itself was discovered; and offers insight into how the world changed afterward and what might happen if such an eruption occurred today. Prothero's riveting account of this calamitous supervolcanic explosion is not to be missed.

Spoon-Fed: Why Almost Everything We’ve Been Told About Food is Wrong


Tim Spector - 2020
    Is salt really bad for you? Is fish good for you? What about coffee, red meat, or saturated fats? Can pregnant women rely on their doctor’s advice about what to eat? Does gluten-free food carry any health benefits at all? Do doctors know anything about nutrition?In twenty short, myth-busting chapters, Tim Spector reveals why almost everything we’ve been told about food is wrong. He reveals the scandalous lack of good scientific evidence for many medical and government food recommendations, and how the food industry holds sway over these policies. These are urgent issues that matter not just for our health as individuals but for the future of the planet.Spoon-Fed forces us to question every diet plan, government recommendation, miracle cure or food label we encounter, and encourages us to rethink our whole relationship with food.

You Are Not So Smart: Why You Have Too Many Friends on Facebook, Why Your Memory Is Mostly Fiction, and 46 Other Ways You're Deluding Yourself


David McRaney - 2011
    Whether you’re deciding which smart phone to purchase or which politician to believe, you think you are a rational being whose every decision is based on cool, detached logic, but here’s the truth: You are not so smart. You’re just as deluded as the rest of us--but that’s okay, because being deluded is part of being human. Growing out of David McRaney’s popular blog, You Are Not So Smart reveals that every decision we make, every thought we contemplate, and every emotion we feel comes with a story we tell ourselves to explain them, but often these stories aren’t true. Each short chapter--covering topics such as Learned Helplessness, Selling Out, and the Illusion of Transparency--is like a psychology course with all the boring parts taken out.Bringing together popular science and psychology with humor and wit, You Are Not So Smart is a celebration of our irrational, thoroughly human behavior.