Our bodies are a quirky mix of new and old, with strokes of genius alongside glitches and imperfections which are all inherited from distant ancestors. Our development and evolutionary past explains why, as embryos, we have what look like gills, and as adults we suffer from back pain.This is a tale of discovery, not only exploring why and how we have developed as we have, but also looking at the history of our anatomical understanding. It combines the remarkable skills and qualifications Alice Roberts has as a doctor, anatomist, osteoarchaeologist and writer. Above all, she has a rare ability to make science accessible, relevant and interesting to mainstream audiences and readers.

    The controversial book linking intelligence to class and race in modern society, and what public policy can do to mitigate socioeconomic differences in IQ, birth rate, crime, fertility, welfare, and poverty.

    He begins with Copernicus, during the Renaissance, when science replaced mysticism as a means of explaining the workings of the world, and he continues through the centuries, creating an unbroken genealogy of not only the greatest but also the more obscure names of Western science, a dot-to-dot line linking amateur to genius, and accidental discovery to brilliant deduction.By focusing on the scientists themselves, Gribbin has written an anecdotal narrative enlivened with stories of personal drama, success and failure. A bestselling science writer with an international reputation, Gribbin is among the few authors who could even attempt a work of this magnitude. Praised as “a sequence of witty, information-packed tales” and “a terrifi c read” by The Times upon its recent British publication, The Scientists breathes new life into such venerable icons as Galileo, Isaac Newton, Albert Einstein and Linus Pauling, as well as lesser lights whose stories have been undeservedly neglected. Filled with pioneers, visionaries, eccentrics and madmen, this is the history of science as it has never been told before.From the Hardcover edition.

    If animals could talk, we would ask them to recall their own ancestries, in particular the secrets as to how they avoided almost inevitable annihilation in the face of daily assaults by predators, climactic cataclysms, deadly infections and innate diseases.In Tears of the Cheetah, medical geneticist and conservationist Stephen J. O'Brien narrates fast-moving science adventure stories that explore the mysteries of survival among the earth's most endangered and beloved wildlife. Here we uncover the secret histories of exotic species such as Indonesian orangutans, humpback whales, and the imperiled cheetah-the world's fastest animal which nonetheless cannot escape its own genetic weaknesses.Among these genetic detective stories we also discover how the Serengeti lions have lived with FIV (the feline version of HIV), where giant pandas really come from, how bold genetic action pulled the Florida panther from the edge of extinction, how the survivors of the medieval Black Death passed on a genetic gift to their descendents, and how mapping the genome of the domestic cat solved a murder case in Canada.With each riveting account of animal resilience and adaptation, a remarkable parallel in human medicine is drawn, adding yet another rationale for species conservation-mining their genomes for cures to our own fatal diseases. Tears of the Cheetah offers a fascinating glimpse of the insight gained when geneticists venutre into the wild.

    In his groundbreaking Before the Dawn, Wade reveals humanity's origins as never before--a journey made possible only recently by genetic science, whose incredible findings have answered such questions as: What was the first human language like? How large were the first societies, and how warlike were they? When did our ancestors first leave Africa, and by what route did they leave? By eloquently solving these and numerous other mysteries, Wade offers nothing less than a uniquely complete retelling of a story that began 500 centuries ago.

    Dehaene's research will fascinate not only readers interested in science and culture, but also educators concerned with debates on how we learn to read, and who wrestle with pathologies such as dyslexia. Like Steven Pinker, Dehaene argues that the mind is not a blank slate: Writing systems across all cultures rely on the same brain circuits, and reading is only possible insofar as it fits within the limits of a primate brain. Setting cutting-edge science in the context of cultural debate, Reading in the Brain is an unparalleled guide to a uniquely human ability.

    Applying the same objective criteria to legal and illegal substances, an argument is made that legality is not a clear measure for harm. Tackling a variety of questions, such as Which is more harmful—Ecstasy or alcohol? Can addiction be cured? and Does the "War on Drugs" have serious unintended effects that can hurt children?, this analysis equips readers with the ability to make educated decisions regarding drugs both personally and in their communities. Broadening the scope of the discussion, a framework is explored for formulating national drug policies that will minimize a myriad of harms—social, medical, criminal, financial, and environmental.

    Gonzalez-Crussi, from the Introduction An international bestseller, translated into eighteen languages, Paul de Kruif’s classic account of the first scientists to see and learn about the microscopic world continues to fascinate new readers. This is a timeless dramatization of the scientists, bacteriologists, doctors, and medical technicians who discovered the microbes and invented the vaccines to counter them. De Kruif writes about how seemingly simple but really fundamental discovers of science—for instance, how a microbe was first viewed in a clear drop of rain water, and when, for the first time, Louis Pasteur discovered that a simple vaccine could save a man from the ravages of rabies by attacking the microbes that cause it.

    While maintaining the hallmark features of previous editions, the Fourth Edition has been completely updated. It includes new Key Concepts at the beginning of each chapter and annotated further reading at the conclusion of each chapter, to help readers navigate the wealth of information in this subject.The text has been restructured so genomic technologies are integrated throughout, and next generation sequencing is included. Genetic testing, screening, approaches to therapy, personalized medicine, and disease models have been brought together in one section. Coverage of cell biology including stem cells and cell therapy, studying gene function and structure, comparative genomics, model organisms, noncoding RNAs and their functions, and epigenetics have all been expanded.

    Nature’s many innovations—some uncannily perfect—call for natural principles that accelerate life’s ability to innovate.”Darwin’s theory of natural selection explains how useful adaptations are preserved over time. But the biggest mystery about evolution eluded him. As genetics pioneer Hugo de Vries put it, “natural selection may explain the survival of the fittest, but it cannot explain the arrival of the fittest.”Can random mutations over a mere 3.8 billion years really be responsible for wings, eyeballs, knees, camouflage, lactose digestion, photosynthesis, and the rest of nature’s creative marvels? And if the answer is no, what is the mechanism that explains evolution’s speed and efficiency?In Arrival of the Fittest, renowned evolutionary biologist Andreas Wagner draws on over fifteen years of research to present the missing piece in Darwin's theory. Using experimental and computational technologies that were heretofore unimagined, he has found that adaptations are not just driven by chance, but by a set of laws that allow nature to discover new molecules and mechanisms in a fraction of the time that random variation would take.Consider the Arctic cod, a fish that lives and thrives within six degrees of the North Pole, in waters that regularly fall below 0 degrees. At that temperature, the internal fluids of most organisms turn into ice crystals. And yet, the arctic cod survives by producing proteins that lower the freezing temperature of its body fluids, much like antifreeze does for a car’s engine coolant. The invention of those proteins is an archetypal example of nature’s enormous powers of creativity. Meticulously researched, carefully argued, evocatively written, and full of fascinating examples from the animal kingdom, Arrival of the Fittest offers up the final puzzle piece in the mystery of life’s rich diversity.

    Focusing on four specific examples — corn, silkworms, domestic cats, and apples — she traces the histories of species that have been fundamentally altered over the centuries by the whims and needs of people.

    Two scientists explore the potential of a revolutionary genetics technology capable of easily and affordably manipulating DNA in human embryos to prevent specific diseases, addressing key concerns about related ethical and societal repercussions.

    Our primitive brains put us on the wrong foot by responding to stimuli that - in prehistoric times - would have prompted behavior that was beneficial. If you've ever felt an anxious fight-or-flight response to presenting at a board meting, equivalent to facing imminent death by saber-toothed tiger, then you have experienced a mismatch.'MISMATCH' is about the clash between our biology and our culture. It is about the dramatic contrast between the first few million years of human history - when humans lived as hunters and gatherers in small-scale societies - and the past 12,000 years following the agricultural revolution which have led us to comfortable lives in a very different social structure. Has this rapid transition been good for us? How do we. using our primitive minds, try to survive in a modern information society that radically changes every 10 years or so?Ronald Giphart and Mark van Vugt show that humans have changed their environment so drastically that the chances for mismatch have significantly increased, and these conflicts can have profound consequences. Reviewed through mismatch glasses, social, societal, and technological trends can be better understood, ranging from the popularity of Facebook and Internet porn to the desire for cosmetic surgery to our attitudes towards refugees. Mismatches can also affect our physical and psychological well-being, in terms of our attitudes to happiness, physical exercise, choosing good leaders, or finding ways to feel better at home or work.Finally, 'MISMATCH' gives us an insight into politics and policy which could enable governments, institutions and businesses to create an environment better suited to human nature, its potential and its constraints. This audiobook is about converting mismatches into matches. The better your life is matched to how your mind operates, the greater your chances of leading a happy, healthy and productive life.RUNNING TIME ⇒ 12hrs. and 48mins.©2018 Ronald Giphart, 2018 Mark van Vugt (P)2018 Hachette Audio Uk

    It touches on its evolutionary development, its algorithmic nature and its scientific history by bridging ideas across Neuroscience, Computer Science, Biotechnology, Evolutionary History, Cognitive Science, Political Philosophy, and Artificial Intelligence.Never before had there been nearly as many scientists, resources or productive research focused on these topics, and humanity has achieved some understanding and some clarification. With the speed of progress it is timely to communicate an overreaching perspective, this book puts an emphasis on conveying the essential questions and what we know about their answers in a simple, clear and exciting way.Humans, along with the first RNA molecules, the first life forms, the first brains, the first conscious animals, the first societies and the first artificial agents constitute an amazing and crucial development in a path of increasingly complex computational intelligence. And yet, we occupy a minuscule time period in the history of Earth, a history that has been written by Genes, by Cultures and by Consciousnesses. If we abandon our anthropomorphic bias it becomes obvious that Humans are not so special after all. We are an important but short and transitory step among many others in a bigger story. The story of our computational minds, which is ours but not only ours. What is the relationship between computation, cognition and everything else? What is life and how did it originate? What is the role of culture in human minds? What do we know about the algorithmic nature of the mind, can we engineer it? What is the computational explanation of consciousness? What are some possible future steps in the evolution of minds? The underlying thread is the computational nature of the Mind which results from the mixture of Genes, Cultures and Consciousness. While these three interact in complex ways, they are ultimately computational systems on their own which appeared at different stages of history and which follow their own selective processes operating at different time scales. As technology progresses, the distinction between the three components materializes and will be a key determinant of the future.Among the many topics covered are the origin of life, the concept of computation and its relation to Turing Machines, cultural evolution and the notion of a Selfish Meme, free will and determinism, moral relativity, the hard problem of consciousness, the different theories of concepts from the perspective of cognitive science, the current status of AI and Machine Learning including the symbolic vs sub-symbolic dichotomy, the contrast between logical reasoning and neural networks, and the recent history of Deep Learning, Geoffrey Hinton, DeepMind and its algorithm AlphaGo. It also develops on the history of science and looks into the possible future building on the work of authors like Daniel Dennett, Yuval Harari, Richard Dawkins, Francis Crick, George Church, David Chalmers, Susan Carey, Stanislas Dehaene, Robert Boyd, Joseph Henrich, Daniel Kahneman, Moran Cerf, Josh Tenenbaum, David Deutsch, Steven Pinker, Ray Kurzweil, John von Neumann, Herbert Simon and many more. Andres Campero is a researcher and PhD student at the Brain and Cognitive Sciences Department and at the Computer Science and Artificial Intelligence Laboratory at the Massachusetts Institute of Technology (MIT).

    In the new edition of Biochemistry, instructors will see the all the hallmark features that made this a consistent bestseller for the undergraduate biochemistry course: exceptional clarity and concision, a more biological focus, cutting-edge content, and an elegant, uncluttered design.  Accomplished in both the classroom and the laboratory, coauthors Jeremy Berg and John Tymoczko draw on the field's dynamic research to illustrate its fundamental ideas.