The Other Brain is the story of glia, which make up approximately 85 percent of the cells in the brain. Long neglected as little more than cerebral packing material ("glia" means glue), glia are sparking a revolution in brain science.Glia are completely different from neurons, the brain cells that we are familiar with. Scientists are discovering that glia have their own communication network, which operates in parallel to the more familiar communication among neurons. Glia provide the insulation for the neurons, and glia even regulate the flow of information between neurons.But it is the potential breakthroughs for medical science that are the most exciting frontier in glia research today. Diseases such as brain cancer and multiple sclerosis are caused by diseased glia. Glia are now believed to play an important role in such psychiatric illnesses as schizophrenia and depression, and in neurodegenerative diseases such as Parkinson's and Alzheimer's. They are linked to infectious diseases such as HIV and prion disease (mad cow disease, for example) and to chronic pain. Scientists have discovered that glia repair the brain and spinal cord after injury and stroke. The more we learn about these cells that make up the "other" brain, the more important they seem to be.Written by a neuroscientist who is a leader in the research to reveal the secrets of these brain cells, The Other Brain offers a firsthand account of science in action. It takes us into the laboratories where important discoveries are being made, and it explains how scientists are learning that glial cells come in different types, with different capabilities. It tells the story of glia research from its origins to the most recent discoveries and gives readers a much more complete understanding of how the brain works and where the next breakthroughs in brain science and medicine are likely to come.

    It is designed to help them understand how the disorder affects their loved ones and recognize what they can do to get off the emotional roller coasters and take care of themselves.

    This cycle is at the root of all addictions, addictions to drugs, sex, love, cigarettes, soap operas, wealth, and wisdom itself. But why should this be so? Why are we desperate for what we don't have, or can't have, often at great cost to what we do have, thereby risking our peace and contentment, our safety, and even our lives?"The answer, says Dr. Marc Lewis, lies in the structure and function of the human brain. Marc Lewis is a distinguished neuroscientist. And, for many years, he was a drug addict himself, dependent on a series of dangerous substances, from LSD to heroin. His narrative moves back and forth between the often dark, compellingly recounted story of his relationship with drugs and a revelatory analysis of what was going on in his brain. He shows how drugs speak to the brain - which is designed to seek rewards and soothe pain - in its own language. He shows in detail the neural mechanics of a variety of powerful drugs and of the onset of addiction, itself a distortion of normal perception.Dr. Lewis freed himself from addiction and ended up studying it. At the age of 30 he traded in his pharmaceutical supplies for the life of a graduate student, eventually becoming a professor of developmental psychology, and then of neuroscience - his field for the last 12 years. This is the story of his journey, seen from the inside out.

    Your brain can't function. You are asked to make decisions about treatment almost immediately, when you are not in your right mind. And yet you pull yourself together and start asking questions. Beside you is your doctor, whose job it is to solve the awful puzzle of bone marrow gone wrong. The two of you are in it together. In When Blood Breaks Down, Mikkael Sekeres, a leading cancer specialist, takes readers on the journey that patient and doctor travel together.Sekeres, who writes regularly for the Well section of the New York Times, tells the compelling stories of three people who receive diagnoses of adult leukemia within hours of each other: Joan, a 48-year-old surgical nurse, a caregiver who becomes a patient; David, a 68-year-old former factory worker who bows to his family's wishes and pursues the most aggressive treatment; and Sarah, a 36-year-old pregnant woman who must decide whether to undergo chemotherapy and put her fetus at risk. We join the intimacy of the conversations Sekeres has with his patients, and watch as he teaches trainees. Along the way, Sekeres also explores leukemia in its different forms and the development of drugs to treat it--describing, among many other fascinating details, the invention of the bone marrow transplant (first performed experimentally on beagles) and a treatment that targets the genetics of leukemia.The lessons to be learned from leukemia, Sekeres shows, are not merely medical; they teach us about courage and grace and defying the odds.

     Although one in five Americans now takes at least one psychotropic drug, the fact remains that nearly seventy years after doctors first began prescribing them, we still don't know exactly how or why these drugs work--or don't work--on what ails our brains. Blue Dreams offers the explosive story of the discovery, invention, people, and science behind our licensed narcotics, as told by a riveting writer and psychologist who shares her own intimate experience with the highs and lows of psychiatry's drugs. Lauren Slater's account ranges from the earliest, Thorazine and lithium, up through Prozac and other antidepressants, as well as Ecstasy, "magic mushrooms," the most cutting-edge memory drugs, and even neural implants. Along the way, she narrates the history of psychiatry itself, illuminating the imprint its colorful little capsules have left on millions of brains worldwide, and demonstrating how these wonder drugs may heal us or hurt us.

    The reality of being poor brings out a survival mentality, and turns attention away from opportunities taken for granted by everyone else. If you work with people from poverty, some understanding of how different their world is from yours will be invaluable. Whether you're an educator--or a social, health, or legal services professional--this breakthrough book gives you practical, real-world support and guidance to improve your effectiveness in working with people from all socioeconomic backgrounds. Since 1995 A Framework for Understanding Poverty has guided hundreds of thousands of educators and other professionals through the pitfalls and barriers faced by all classes, especially the poor. Carefully researched and packed with charts, tables, and questionnaires, Framework not only documents the facts of poverty, it provides practical yet compassionate strategies for addressing its impact on people's lives.

    He made life worth living. But most importantly, he empowered me to find and reclaim myself again' Lady GagaDo the work to heal yourself and find a path through trauma.Trauma is everywhere and so many of us are silently affected by it. Stressful, challenging and frightening events can happen to anyone, at any age, leaving us feeling overwhelmed, anxious and exhausted. Left unchecked, difficult experiences can have a lasting psychological effect on our wellbeing.In Trauma: The Invisible Epidemic, leading psychiatrist Dr Paul Conti sets out a unique set of tools anyone can access to help recognise the signs of trauma, heal from past hurt and find the road to recovery.Drawing on the most recent scientific research, Dr Conti breaks down the topic into clear sections, looking at why trauma happens, how it manifests in the body and what we can do to move past it. In the book, you'll discover the three different types of trauma you might face, as well as practical exercises and solutions for getting to the root of the problem.This is an important, life-affirming book, one that invites you to empower yourself against trauma, own your life experiences and learn to thrive, not just survive, in the wake of life's difficulties.

    But a recent groundbreaking discovery revealed them to be capable of terrifying Jekyll and Hyde behavior. When triggered--and anything that stirs up the immune system in the body can activate microglia--they can morph into destroyers, impacting a wide range of issues from memory problems and anxiety to depression and Alzheimer's. Under the right circumstances, however, microglia can be coaxed back into being angelic healers, able to repair the brain in ways that help alleviate symptoms and hold the promise to one day prevent disease.A fascinating behind-the-scenes account of this cutting-edge science, The Angel and the Assassin also explores the medical implications of these game-changing discoveries. Award-winning journalist Donna Jackson Nakazawa began her investigation with a personal interest--when diagnosed with an autoimmune disorder years ago, she was convinced there was something physical going on in her brain as well as her body, though no doctor she consulted could explain how the two could be interacting in this way. With the compassion born of her own experience, she follows practitioners and patients on the front lines of treatments that help to "reboot" microglia--from neurofeedback and intermittent fasting to transcranial magnetic stimulation and gamma light flicker therapy. She witnesses patients finding significant relief from pressing symptoms--and at least one stunning recovery--offering new hope to the tens of millions who suffer from mental, cognitive, and physical health issues.Proving once and for all the biological basis for the mind-body connection, the discovery of the true role of microglia stands to rewrite psychiatric and medical texts as we know them. Hailed as "riveting," "stunning," and "visionary," The Angel and the Assassin offers us a radically reconceived picture of human health and promises to change everything we thought we knew about how to heal ourselves.

    Among the notorious murderers she has examined are Ted Bundy, Arthur Shawcross, and Mark David Chapman, the man who shot John Lennon. Now she shares her groundbreaking discoveries--and the chilling encounters that led to them.From a juvenile court in Connecticut to the psychiatric wards of New York City's Bellevue Hospital, from maximum security prisons to the corridors of death row, Lewis and her colleague, the eminent neurologist Jonathan Pincus, search to understand the origins of violence. Guilty by Reason of Insanity is an utterly absorbing odyssey that will forever change the way you think about crime, punishment, and the law itself.

    We hurt ourselves, we feel pain, we seek help from a professional or learn to avoid certain behaviors that cause pain. But the story of what goes on in our body is far from simple. Even medical practitioners themselves often fail to grasp the complexities between our minds and bodies and how they interact when dealing with pain stimulus. Throughout history we’ve tried to prevent and mediate the effects of pain—which has only resulted in a highly medicated population and a booming opiates industry. Written by a medical expert trained as an anesthesiologist, An Anatomy of Pain is the first book to clearly explain the current issues and complexities surrounding the treatment of pain and how society deals with those in pain, as well as how our bodies relate to pain. Common conception still equates pain with tissue damage but that is only a very small part of the story—the organ which produces pain is the brain. Case studies show that a woman who has undergone a c-section reports dramatically less pain than a patient who has had kidney stones removed in a similarly invasive operation. The soldier who drags himself or herself to safety after being shot deals with pain in a remarkably different way from someone suffering a similar injury on a street. The truth is that pain is a complex mix of nerve endings, psychological state, social preconceptions, and situational awareness. Filled with case studies and medical history, this enlightening book offers a crash course in all aspects of pain, from chronic to acute, and walks us through the current landscape of pain treatments—from medication (including opioids) to electrical nerve stimulation. Whether it’s a mild ache or severe discomfort, we all encounter pain in our lives and “this splendid book—informative, empathic, and wise—about a universal experience will surely promote healing” (Booklist, starred review).

    While studying brain scans of several family members, he discovered that one perfectly matched a pattern he d found in the brains of serial killers. This meant one of two things: Either his family s scans had been mixed up with those of felons or someone in his family was a psychopath.Even more disturbing: The scan in question was his own.This is Fallon s account of coming to grips with this discovery and its implications. How could he, a happy family man who had never been prone to violence, be a psychopath? How much did his biology influence his behavior?Fallon shares his journey to answer these questions and the discoveries that ultimately led to his conclusion: Despite everything science can teach, humans are even more complex than we can imagine."

    The personal memoir of a manic depressive and an authority on the subject describes the onset of the illness during her teenage years and her determined journey through the realm of available treatments.

    Their extraordinary meeting and the two years they spent in one another’s company serves as the basis for an investigation into the nature of human identity, belief, and delusion that is poignant, amusing, and at times disturbing. Displaying the sympathy and subtlety of a gifted novelist, Rokeach draws us into the lives of three troubled and profoundly different men who find themselves “confronted with the ultimate contradiction conceivable for human beings: more than one person claiming the same identity.”

    Often they appear to be normally functioning at work and in public interactions, and Narcissists may even be highly effective, in the short term, in some work or social situations. However, in intimate relationships, they can be emotional, aggressive, demeaning, illogical, paranoid, accusing, and controlling--in the extreme. Their ability to function normally or pleasantly can suddenly change in an instant, like flipping a switch. These negative behaviors don't happen once in a while, they happen almost continuously in their intimate relationships and most often, and especially with their Caretaker family member.Here, Margalis Fjelstad describes how people get into a Caretaker role with a Borderline or Narcissist, and how they can get out. Caretakers give up their sense of self to become who and what the Borderline or Narcissist needs them to be. This compromises the Caretaker's self-esteem, distorts their thinking processes, and locks them into a Victim-Persecutor-Rescuer pattern with the Borderline or Narcissist. The book looks at the underlying rules and expectations in these relationships and shows Caretaker's how to move themselves out of these rigid interactions and into a healthier, more productive, and positive lifestyle--with or without the Borderline/Narcissistic partner or family member. It describes how to get out of destructive interactions with the Borderline or Narcissist and how to take new, more effective actions to focus on personal wants, needs, and life goals while allowing the Borderline or Narcissist to take care of themselves. It presents a realistic, yet compassionate, attitude toward the self-destructive nature of these relationships, and gives real life examples of how individuals have let go of their Caretaker behaviors with creative and effective solutions.--Elayne Savage, PhD, relationship and workplace coach; professional speaker; author of Don't Take It Personally! The Art of Dealing with Rejection and Breathing Room - Creating Space to Be a Couple

    Jails in New York, Los Angeles, and Chicago each house more people with mental illnesses than any hospital. As many as half of all people in America's jails and prisons have a psychiatric disorder. One in four fatal police shootings involves a person with such disorders.In this revelatory book, journalist Alisa Roth goes deep inside the criminal justice system to show how and why it has become a warehouse where inmates are denied proper treatment, abused, and punished in ways that make them sicker.Through intimate stories of people in the system and those trying to fix it, Roth reveals the hidden forces behind this crisis and suggests how a fairer and more humane approach might look. Insane is a galvanizing wake-up call for criminal justice reformers and anyone concerned about the plight of our most vulnerable.