These were the concerns of Socrates, who spent his days in the ancient Athenian marketplace asking awkward questions, disconcerting the people he met by showing them how little they genuinely understood. This engaging book introduces the great thinkers in Western philosophy and explores their most compelling ideas about the world and how best to live in it.In forty brief chapters, Nigel Warburton guides us on a chronological tour of the major ideas in the history of philosophy. He provides interesting and often quirky stories of the lives and deaths of thought-provoking philosophers from Socrates, who chose to die by hemlock poisoning rather than live on without the freedom to think for himself, to Peter Singer, who asks the disquieting philosophical and ethical questions that haunt our own times.Warburton not only makes philosophy accessible, he offers inspiration to think, argue, reason, and ask in the tradition of Socrates. A Little History of Philosophy presents the grand sweep of humanity's search for philosophical understanding and invites all to join in the discussion.

    She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    He left quiet Cambridge, where he had lived for thirty years and made his earth-shattering discoveries, and moved to London to take up the post of Warden of His Majesty’s Mint. Newton was preceded to the city by a genius of another kind, the budding criminal William Chaloner. Thanks to his preternatural skills as a counterfeiter, Chaloner was rapidly rising in London’s highly competitive underworld, at a time when organized law enforcement was all but unknown and money in the modern sense was just coming into being. Then he crossed paths with the formidable new warden. In the courts and streets of London—and amid the tremors of a world being transformed by the ideas Newton himself had set in motion—the two played out an epic game of cat and mouse.

    Like you, the elements have lives: personalities and attitudes, talents and shortcomings, stories rich with meaning. You may think of them as the inscrutable letters of the periodic table but you know them much better than you realise. Welcome to a dazzling tour through history and literature, science and art. Here you'll meet iron that rains from the heavens and noble gases that light the way to vice. You'll learn how lead can tell your future while zinc may one day line your coffin. You'll discover what connects the bones in your body with the Whitehouse in Washington, the glow of a streetlamp with the salt on your dinner table. From ancient civilisations to contemporary culture, from the oxygen of publicity to the phosphorus in your pee, the elements are near and far and all around us. Unlocking their astonishing secrets and colourful pasts, Periodic Tales will take you on a voyage of wonder and discovery, excitement and novelty, beauty and truth. Along the way, you'll find that their stories are our stories, and their lives are inextricable from our own.

    In her previous book, The Well-Trained Mind, the author provided a road map of classical education for parents wishing to home-school their children, and that book is now the premier resource for home-schoolers. In this new book, Bauer takes the same elements and techniques and adapts them to the use of adult readers who want both enjoyment and self-improvement from the time they spend reading.The Well-Educated Mind offers brief, entertaining histories of five literary genres—fiction, autobiography, history, drama, and poetry—accompanied by detailed instructions on how to read each type. The annotated lists at the end of each chapter—ranging from Cervantes to A. S. Byatt, Herodotus to Laurel Thatcher Ulrich—preview recommended reading and encourage readers to make vital connections between ancient traditions and contemporary writing.The Well-Educated Mind reassures those readers who worry that they read too slowly or with below-average comprehension. If you can understand a daily newspaper, there's no reason you can't read and enjoy Shakespeare's Sonnets or Jane Eyre. But no one should attempt to read the "Great Books" without a guide and a plan. Susan Wise Bauer will show you how to allocate time to your reading on a regular basis; how to master a difficult argument; how to make personal and literary judgments about what you read; how to appreciate the resonant links among texts within a genre—what does Anna Karenina owe to Madame Bovary?—and also between genres. Followed carefully, the advice in The Well-Educated Mind will restore and expand the pleasure of the written word.

    Now Lawrence M. Krauss, an internationally known theoretical physicist and educator, has written the quintessential physics book for Trekkers and non-Trekkers alike.Anyone who has ever wondered, "Could this really happen?" will gain useful insights into the "Star Trek" universe (and, incidentally, the real universe) in this charming and accessible volume. Krauss boldly goes where "Star Trek" has gone -- and beyond. He uses the "Star Trek" future as a launching pad to discuss the forefront of modern physics. From Newton to Hawking, from Einstein to Feynman, from Kirk to Janeway, Krauss leads the reader on a voyage to the world of physics as we now know it and as it might one day be.Featuring the Top 10 biggest physics bloopers in "Star Trek," as selected by Nobel Prize-winning physicists and other dedicated Trekkers!"This book is fun, and Mr. Krauss has a nice touch with a tough subject...Readers drawn by frivolity will be treated to substance." "--New York Times Book Review""Today's science fiction is often tomorrow's science fact. The physics that underlies "Star Trek" is surely worth investigating. To confine our attention to terrestrial matters would be to limit the human spirit."--Stephen Hawking (in the foreword)A

    Now, for the first time, this EGOT (Emmy, Grammy, Oscar, Tony) winner shares his story in his own words. “I hope fans of comedy will get a kick out of the stories behind my work, and really enjoy taking this remarkable ride with me.”—Mel Brooks For anyone who loves American comedy, the long wait is over. Here are the never-before-told, behind-the-scenes anecdotes and remembrances from a master storyteller, filmmaker, and creator of all things funny.All About Me! charts Mel Brooks’s meteoric rise from a Depression-era kid in Brooklyn to the recipient of the National Medal of Arts. Whether serving in the United States Army in World War II, or during his burgeoning career as a teenage comedian in the Catskills, Mel was always mining his experiences for material, always looking for the perfect joke. His iconic career began with Sid Caesar’s Your Show of Shows, where he was part of the greatest writers’ room in history, which included Carl Reiner, Neil Simon, and Larry Gelbart. After co-creating both the mega-hit 2000 Year Old Man comedy albums and the classic television series Get Smart, Brooks’s stellar film career took off. He would go on to write, direct, and star in The Producers, The Twelve Chairs, Blazing Saddles, Young Frankenstein, Silent Movie, High Anxiety, and Spaceballs, as well as produce groundbreaking and eclectic films, including The Elephant Man, The Fly, and My Favorite Year. Brooks then went on to conquer Broadway with his record-breaking, Tony-winning musical, The Producers. All About Me! offers fans insight into the inspiration behind the ideas for his outstanding collection of boundary-breaking work, and offers details about the many close friendships and collaborations Brooks had, including those with Sid Caesar, Carl Reiner, Gene Wilder, Madeleine Kahn, Alfred Hitchcock, and the great love of his life, Anne Bancroft. Filled with tales of struggle, achievement, and camaraderie (and dozens of photographs), readers will gain a more personal and deeper understanding of the incredible body of work behind one of the most accomplished and beloved entertainers in history.

    In barely six years, a small group of young, ambitious programmers in Silicon Valley built an $11.5 billion business out of the ashes of a failed podcasting company. Today Twitter boasts more than 200 million active users and has affected business, politics, media, and other fields in innumerable ways. Now Nick Bilton of the New York Times takes readers behind the scenes with a narrative that shows what happened inside Twitter as it grew at exponential speeds. This is a tale of betrayed friendships and high-stakes power struggles as the four founders—Biz Stone, Evan Williams, Jack Dorsey, and Noah Glass—went from everyday engineers to wealthy celebrities, featured on magazine covers, Oprah, The Daily Show, and Time’s list of the world’s most influential people. Bilton’s exclusive access and exhaustive investigative reporting—drawing on hundreds of sources, documents, and internal e-mails—have enabled him to write an intimate portrait of fame, influence, and power. He also captures the zeitgeist and global influence of Twitter, which has been used to help overthrow governments in the Middle East and disrupt the very fabric of the way people communicate.

    USA Today calls this fascinating, entertaining, and blissfully nostalgic look back, “Invaluable.” In The Road to Woodstock, Michael Lang recaptures the magic for the generation that was there…and for the generations that followed.

    Now, in What the Dog Saw, he brings together, for the first time, the best of his writing from The New Yorker over the same period. Here you'll find the bittersweet tale of the inventor of the birth control pill, and the dazzling creations of pasta sauce pioneer Howard Moscowitz. Gladwell sits with Ron Popeil, the king of the American kitchen, as he sells rotisserie ovens, and divines the secrets of Cesar Millan, the "dog whisperer" who can calm savage animals with the touch of his hand. He explores intelligence tests and ethnic profiling and why it was that employers in Silicon Valley once tripped over themselves to hire the same college graduate.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    Her compelling and demanding collection The Death of Adam—in which she reflected on her Presbyterian upbringing, investigated the roots of Midwestern abolitionism, and mounted a memorable defense of Calvinism—is respected as a classic of the genre, praised by Doris Lessing as “a useful antidote to the increasingly crude and slogan-loving culture we inhabit.” In this new collection she returns to the themes which have preoccupied her work: the role of faith in modern life, the inadequacy of fact, the contradictions inherent in human nature. Clear-eyed and forceful as ever, Robinson demonstrates once again why she is regarded as a modern rhetorical master.

    In riveting first-person prose, Dr. Brendan Reilly takes us to the front lines of medicine today. Whipsawed by daily crises and frustrations, Reilly must deal with several daunting challenges simultaneously: the extraordinary patients under his care on the teeming wards of a renowned teaching hospital; the life-threatening illnesses of both of his ninety-year-old parents; and the tragic memory of a cold case from long ago that haunts him still. As Reilly’s patients and their families survive close calls, struggle with heartrending decisions, and confront the limits of medicine’s power to cure, One Doctor lays bare a fragmented, depersonalized, business-driven health-care system where real caring is hard to find. Every day, Reilly sees patients who fall through the cracks and suffer harm because they lack one doctor who knows them well and relentlessly advocates for their best interests.Filled with fascinating characters in New York City and rural New England — people with dark secrets, mysterious illnesses, impossible dreams, and many kinds of courage — One Doctor tells their stories with sensitivity and empathy, reminding us of professional values once held dear by all physicians. But medicine has changed enormously during Reilly’s career, for both better and worse, and One Doctor is a cautionary tale about those changes. It is also a hopeful, inspiring account of medicine’s potential to improve people’s lives, Reilly’s quest to understand the "truth" about doctoring, and a moving testament to the difference one doctor can make.

    Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    For each occasion, Vonnegut's words were unfailingly unique, insightful, and witty, and they stayed with audience members long after graduation.This expanded second edition includes more than sixty pages of further thoughts from Kurt (whose good advice wasn’t limited to graduation speeches).As edited by Dan Wakefield, this book reads like a narrative in the unique voice that made Vonnegut a hero to readers of all ages. At times hilarious, razor-sharp, freewheeling, and deeply serious, these reflections are ideal for anyone undergoing what Vonnegut would call their “long-delayed puberty ceremony”—marking the passage from student to full-time adult.