After World War II, Don's work with the Air Force brought them to Colorado, where their twelve children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins—aspiration, hard work, upward mobility, domestic harmony—and they worked hard to play their parts. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the ten Galvin boys, one after another, were diagnosed as schizophrenic. How could all this happen to one family?What took place inside the house on Hidden Valley Road was so extraordinary that the Galvins became one of the first families to be studied by the National Institute of Mental Health. Their story offers a shadow history of the science of schizophrenia, from the era of institutionalization, lobotomy, and the schizophrenogenic mother to the search for genetic markers for the disease, always amid profound disagreements about the nature of the illness itself. And unbeknownst to the Galvins, samples of their DNA informed decades of genetic research that continues today, offering paths to treatment, prediction, and even eradication of the disease for future generations.With clarity and compassion, bestselling and award-winning author Robert Kolker uncovers one family's unforgettable legacy of suffering, love, and hope.

    Once the watchwords of feminism, these terms have now been co-opted by a society that sells women an airbrushed, highly sexualised and increasingly narrow vision of femininity. While the opportunities available to women may have expanded, the ambitions of many young girls are in reality limited by a culture that sees women's sexual allure as their only passport to success. At the same time we are encouraged to believe that the inequality we observe all around us is born of innate biological differences rather than social factors. Drawing on a wealth of research and personal interviews, Natasha Walter, author of the groundbreaking THE NEW FEMINISM and one of Britain's most incisive cultural commentators, gives us a straight-talking, passionate and important book that makes us look afresh at women and girls, at sexism and femininity, today.

    She did.Sophie navigates being the only black scientist in her lab while studying the very disease, HIV, that she hides from her coworkers.For Victoria, coming out as a transgender woman was less difficult than coming out as bipolar.Author Michele Lent Hirsch knew she couldn't be the only woman who's faced serious health issues at a young age, as well as the resulting effects on her career, her relationships, and her sense of self. What she found while researching Invisible was a surprisingly large and overlooked population with important stories to tell.Though young women with serious illness tend to be seen as outliers, young female patients are in fact the primary demographic for many illnesses. They are also one of the most ignored groups in our medical system--a system where young women, especially women of color and trans women, are invisible.And because of expectations about gender and age, young women with health issues must often deal with bias in their careers and personal lives. Not only do they feel pressured to seem perfect and youthful, they also find themselves amid labyrinthine obstacles in a culture that has one narrow idea of womanhood.Lent Hirsch weaves her own harrowing experiences together with stories from other women, perspectives from sociologists on structural inequality, and insights from neuroscientists on misogyny in health research. She shows how health issues and disabilities amplify what women in general already confront: warped beauty standards, workplace sexism, worries about romantic partners, and mistrust of their own bodies. By shining a light on this hidden demographic, Lent Hirsch explores the challenges that all women face.

    But it wasn’t long before they noticed a marked difference between Jonas and his brother, Wyatt. Jonas preferred sports and trucks and many of the things little boys were “supposed” to like; but Wyatt liked princess dolls and dress-up and playing Little Mermaid. By the time the twins were toddlers, confusion over Wyatt’s insistence that he was female began to tear the family apart. In the years that followed, the Maineses came to question their long-held views on gender and identity, to accept and embrace Wyatt’s transition to Nicole, and to undergo an emotionally wrenching transformation of their own that would change all their lives forever.Becoming Nicole chronicles a journey that could have destroyed a family but instead brought it closer together. It’s the story of a mother whose instincts told her that her child needed love and acceptance, not ostracism and disapproval; of a Republican, Air Force veteran father who overcame his deepest fears to become a vocal advocate for trans rights; of a loving brother who bravely stuck up for his twin sister; and of a town forced to confront its prejudices, a school compelled to rewrite its rules, and a courageous community of transgender activists determined to make their voices heard. Ultimately, Becoming Nicole is the story of an extraordinary girl who fought for the right to be herself.Granted wide-ranging access to personal diaries, home videos, clinical journals, legal documents, medical records, and the Maineses themselves, Amy Ellis Nutt spent almost four years reporting this immersive account of an American family confronting an issue that is at the center of today’s cultural debate. Becoming Nicole will resonate with anyone who’s ever raised a child, felt at odds with society’s conventions and norms, or had to embrace life when it plays out unexpectedly. It’s a story of standing up for your beliefs and yourself—and it will inspire all of us to do the same.

    It’s a fly-on-the-wall account of the titanic fight to pass a 961-page law aimed at fixing America’s largest, most dysfunctional industry. It’s a penetrating chronicle of how the profiteering that Brill first identified in his trailblazing Time magazine cover story continues, despite Obamacare. And it is the first complete, inside account of how President Obama persevered to push through the law, but then failed to deal with the staff incompetence and turf wars that crippled its implementation.   But by chance America’s Bitter Pill ends up being much more—because as Brill was completing this book, he had to undergo urgent open-heart surgery. Thus, this also becomes the story of how one patient who thinks he knows everything about healthcare “policy” rethinks it from a hospital gurney—and combines that insight with his brilliant reporting. The result: a surprising new vision of how we can fix American healthcare so that it stops draining the bank accounts of our families and our businesses, and the federal treasury. Praise for America’s Bitter Pill   “A tour de force . . . a comprehensive and suitably furious guide to the political landscape of American healthcare . . . persuasive, shocking.”—The New York Times   “An energetic, picaresque, narrative explanation of much of what has happened in the last seven years of health policy . . . [Brill] has pulled off something extraordinary.” —The New York Times Book Review   “A thunderous indictment of what Brill refers to as the ‘toxicity of our profiteer-dominated healthcare system.’ ”—Los Angeles Times  “A sweeping and spirited new book [that] chronicles the surprisingly juicy tale of reform.”—The Daily Beast  “One of the most important books of our time.”—Walter Isaacson   “Superb . . . Brill has achieved the seemingly impossible—written an exciting book about the American health system.”—The New York Review of Books

    After barely surviving the agony of smallpox themselves, they flouted eighteenth-century medicine by borrowing folk knowledge from African slaves and Eastern women in frantic bids to protect their children. From their heroic struggles stems the modern science of immunology as well as the vaccinations that remain our only hope should the disease ever be unleashed again.Jennifer Lee Carrell transports readers back to the early eighteenth century to tell the tales of Lady Mary Wortley Montagu and Dr. Zabdiel Boylston, two iconoclastic figures who helped save London and Boston from the deadliest disease mankind has known.

    We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

    This is a no-holds-barred response to the liberal and conservative retreat from an assertive, activist, and socially transformative civil rights agenda of recent years--using a black feminist lens and the issue of  the impact of recent legislation, social policy, and welfare "reform" on black women's--especially poor black women's--control over their bodies' autonomy and their freedom to bear and raise children with respect and dignity in a society whose white mainstream is determined to demonize, even criminalize their lives.   It gives its readers a cogent legal and historical argument for a radically new , and socially transformative, definition of  "liberty" and "equality" for the American polity from a black feminist perspective.The author is able to combine the most innovative and radical thinking on several fronts--racial theory, feminist, and legal--to produce a work that is at once history and political treatise.  By using the history of how American law--beginning with slavery--has treated the issue of the state's right  to interfere with the black woman's body, the author explosively and effectively makes the case for the legal redress to the racist implications of current policy with regards to 1) access to and coercive dispensing of birth control to poor black women 2) the criminalization of parenting by poor black women who have used drugs 3) the stigmatization and devaluation of poor black mothers under the new welfare provisions, and 4) the differential access to and disproportionate spending of social resources on the new reproductive technologies used by wealthy white couples to insure genetically related offspring.The legal redress of the racism inherent in current  American law and policy in these matters, the author argues in her last chapter, demands and should lead us to adopt a new standard and definition of the liberal theory of "liberty" and "equality" based on the need for, and the positive role of government in fostering, social as well as individual justice.

    But it’s not actually a joke. Having a spouse who takes care of things at home is a Godsend on the domestic front. It’s a potent economic asset on the work front. And it’s an advantage enjoyed – even in our modern society – by vastly more men than women.Working women are in an advanced, sustained, and chronically under-reported state of wife drought, and there is no sign of rain.But why is the work-and-family debate always about women? Why don’t men get the same flexibility that women do? In our fixation on the barriers that face women on the way into the workplace, do we forget about the barriers that – for men – still block the exits?The Wife Drought is about women, men, family and work. Written in Annabel Crabb’s inimitable style, it’s full of candid and funny stories from the author's work in and around politics and the media, historical nuggets about the role of ‘The Wife’ in Australia, and intriguing research about the attitudes that pulse beneath the surface of egalitarian Australia.Crabb's call is for a ceasefire in the gender wars. Rather than a shout of rage, The Wife Drought is the thoughtful, engaging catalyst for a conversation that's long overdue.

    Anthony Fauci is a hero. He is anything but. As director of the National Institute of Allergy and Infectious Diseases (NIAID), Dr. Anthony Fauci dispenses $6.1 billion in annual taxpayer-provided funding for scientific research, allowing him to dictate the subject, content, and outcome of scientific health research across the globe. Fauci uses the financial clout at his disposal to wield extraordinary influence over hospitals, universities, journals, and thousands of influential doctors and scientists—whose careers and institutions he has the power to ruin, advance, or reward. During more than a year of painstaking and meticulous research, Robert F. Kennedy Jr. unearthed a shocking story that obliterates media spin on Dr. Fauci . . . and that will alarm every American—Democrat or Republican—who cares about democracy, our Constitution, and the future of our children’s health. The Real Anthony Fauci reveals how “America’s Doctor” launched his career during the early AIDS crisis by partnering with pharmaceutical companies to sabotage safe and effective off-patent therapeutic treatments for AIDS. Fauci orchestrated fraudulent studies, and then pressured US Food and Drug Administration (FDA) regulators into approving a deadly chemotherapy treatment he had good reason to know was worthless against AIDS. Fauci repeatedly violated federal laws to allow his Pharma partners to use impoverished and dark-skinned children as lab rats in deadly experiments with toxic AIDS and cancer chemotherapies. In early 2000, Fauci shook hands with Bill Gates in the library of Gates’ $147 million Seattle mansion, cementing a partnership that would aim to control an increasingly profitable $60 billion global vaccine enterprise with unlimited growth potential. Through funding leverage and carefully cultivated personal relationships with heads of state and leading media and social media institutions, the Pharma-Fauci-Gates alliance exercises dominion over global health policy. The Real Anthony Fauci details how Fauci, Gates, and their cohorts use their control of media outlets, scientific journals, key government and quasi-governmental agencies, global intelligence agencies, and influential scientists and physicians to flood the public with fearful propaganda about COVID-19 virulence and pathogenesis, and to muzzle debate and ruthlessly censor dissent.

    Joshua Mezrich creates life from loss, transplanting organs from one body to another. In this intimate, profoundly moving work, he illuminates the extraordinary field of transplantation that enables this kind of miracle to happen every day.When Death Becomes Life is a thrilling look at how science advances on a grand scale to improve human lives. Mezrich examines more than one hundred years of remarkable medical breakthroughs, connecting this fascinating history with the inspiring and heartbreaking stories of his transplant patients. Combining gentle sensitivity with scientific clarity, Mezrich reflects on his calling as a doctor and introduces the modern pioneers who made transplantation a reality—maverick surgeons whose feats of imagination, bold vision, and daring risk taking generated techniques and practices that save millions of lives around the world.Mezrich takes us inside the operating room and unlocks the wondrous process of transplant surgery, a delicate, intense ballet requiring precise timing, breathtaking skill, and at times, creative improvisation. In illuminating this work, Mezrich touches the essence of existence and what it means to be alive. Most physicians fight death, but in transplantation, doctors take from death. Mezrich shares his gratitude and awe for the privilege of being part of this transformative exchange as the dead give their last breath of life to the living. After all, the donors are his patients, too.When Death Becomes Life also engages in fascinating ethical and philosophical debates: How much risk should a healthy person be allowed to take to save someone she loves? Should a patient suffering from alcoholism receive a healthy liver? What defines death, and what role did organ transplantation play in that definition? The human story behind the most exceptional medicine of our time, Mezrich’s riveting book is a beautiful, poignant reminder that a life lost can also offer the hope of a new beginning.

    Now, however, conversation has turned to whether it's necessary to have it all or, perhaps more controversial, whether children are really a requirement for a fulfilling life. The idea that some women and men prefer not to have children is often met with sharp criticism and incredulity by the public and mainstream media.In this provocative and controversial collection of essays, curated by writer Meghan Daum, sixteen acclaimed writers explain why they have chosen to eschew parenthood. Contributors Lionel Shriver, Sigrid Nunez, Kate Christiensen, Elliott Holt, Geoff Dyer, and Tim Kreider, among others, offer a unique perspective on the overwhelming cultural pressure of parenthood.Selfish, Shallow, and Self-Absorbed makes a thoughtful and passionate case for why parenthood is not the only path in life, taking our parent-centric, kid-fixated, baby-bump-patrolling culture to task in the process. What emerges is a more nuanced, diverse view of what it means to live a full, satisfying life.

    The disintegration of this group, a process that has been slowly occurring now for more than forty years, has been reported with growing frequency and alarm, but has never before been written about as searingly from the inside. J. D. Vance tells the true story of what a social, regional, and class decline feels like when you were born with it hung around your neck.The Vance family story begins hopefully in postwar America. J. D.’s grandparents were “dirt poor and in love,” and moved north from Kentucky’s Appalachia region to Ohio in the hopes of escaping the dreadful poverty around them. They raised a middle-class family, and eventually one of their grandchildren would graduate from Yale Law School, a conventional marker of success in achieving generational upward mobility. But as the family saga of Hillbilly Elegy plays out, we learn that J.D.'s grandparents, aunt, uncle, sister, and, most of all, his mother struggled profoundly with the demands of their new middle-class life, never fully escaping the legacy of abuse, alcoholism, poverty, and trauma so characteristic of their part of America. With piercing honesty, Vance shows how he himself still carries around the demons of his chaotic family history.A deeply moving memoir, with its share of humor and vividly colorful figures, Hillbilly Elegy is the story of how upward mobility really feels. And it is an urgent and troubling meditation on the loss of the American dream for a large segment of this country.

    Linda Tirado, in her signature brutally honest yet personable voice, takes all of these preconceived notions and smashes them to bits. She articulates not only what it is to be working poor in America (yes, you can be poor and live in a house and have a job, even two), but what poverty is truly like—on all levels. Frankly and boldly, Tirado discusses openly how she went from lower-middle class, to sometimes middle class, to poor and everything in between, and in doing so reveals why “poor people don’t always behave the way middle-class America thinks they should.”

    Angier takes readers on a mesmerizing tour of female anatomy and physiology that explores everything from organs to orgasm, and delves into topics such as exercise, menopause, and the mysterious properties of breast milk.A self-proclaimed "scientific fantasia of womanhood." Woman ultimately challenges widely accepted Darwinian-based gender stereotypes. Angier shows how cultural biases have influenced research in evolutionary psychology (the study of the biological bases of behavior) and consequently led to dubious conclusions about "female nature." such as the idea that women are innately monogamous while men are natural philanderers.But Angier doesn't just point fingers; she offers optimistic alternatives and transcends feminist polemics with an enlightened subversiveness that makes for a joyful, fresh vision of womanhood. Woman is a seminal work that will endure as an essential read for anyone intersted in how biology affects who we are as women, as men, and as human beings.