The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    From miraculous pregnancies to dirty protests, and from violent attacks on prisoners to heartbreaking acts of self-harm, she has witnessed it all. In this memoir, Amanda reveals the stories, the patients and the cases that have shaped a career helping those most of us would rather forget.

    The Cell: a Molecular Approach meets this challenge by providing students with not only the current information, but also with an introduction to the experimental nature of contemporary research. Designed for use in introductory cell biology courses, The Cell presents current, comprehensive science in a readable and cohesive text that students can master in the course of one semester. The new third edition of The Cell retains the organization, themes, and special features of earlier editions, but is updated to reflect scientific advances since publication of the second edition, including progress in genome sequencing, advances in understanding transcriptional regulation and mRNA processing, use of DNA microarrays in global studies of gene expression and cancer diagnostics, advances in nuclear transport and protein trafficking, progress in understanding the regulation of programmed cell death, potential medical applications of embryonic cells, and development of oncogene-targeted treatments. Key Experimental boxes in each chapter describe seminal experiments in modern cell biology, showing the detail and background to give students a sense of doing science. Molecular Medicine boxes relate basic science to clinical practice or potential and show the excitement of molecular discovery and solutions to disease. Chapter summaries are organized in outline form corresponding to the major sections and subsections of each chapter. This section-by-section format is coupled with a list of the key terms introduced in eachsection, providing a succinct but comprehensive review of the material. The full-color art program is both pedagogically and scientifically outstanding. In addition, each chapter includes a brief chapter outline, boldfaced key terms (also defined in the glossary), and many new chapter-end questions with answers in the back of the book. With a clear focus on cell biology as an integrative theme, topics such as developmental biology, plant biology, the immune system, the nervous system, and muscle physiology are covered in their broader biological context. The book can be bundled for purchase with a special edition of Molecules, Cells, and Genes, a CD-ROM keyed to the textbook and combining the essential features of a Study Guide and Problems book.

    People need cheering up. I have the answer. ‘Pills, Thrills and Methadone Spills: Adventures of a Community Pharmacist’ is a collection of the best blogs, tweets and anecdotes about the wonderful world of pharmacy.“If the shutter is three quarters down, then we are shut and not just vertically challenged”...“Gave me huge insight into the ‘real’ world of community pharmacy – I didn’t realise just how much pharmacists deal with on a day to day basis, so for me this was very informative, but in a reallyclever, and massively funny way!” Lucy Pitt, Marketing Manager, The Pharmacy Show“As well as being brilliantly funny, this book is a refreshingly honest view of the world of pharmacy. From student pharmacists to the fully-qualified, every chapter provides a story that the reader can relate to and enjoy.” Georgia Salter, Pharmacy Student“A well observed reflection of life in pharmacy with very funny reflections” Catherine Duggan, Royal Pharmaceutical Society"It is always fun to be reminded that pharmacists' perils and fun at the workplace are similar irrespective of which country we practise in!" Selina Hui-Hoong Wee , Pharmacist, Malaysia“A great entertaining and amusing read" Mike Holden, Chief Executive, National Pharmacy AsociationThanks to Laura Martins for her initial book cover design!

    Provides a chronology of seven thousand years of significant moments in history, religion, science, and the arts in an accessible format designed for quick reference.

    Sherwin Nuland, “a gifted and deeply intelligent writer” (San Francisco Chronicle), combines knowledge, compassion, and elegance of expression to shed light on the workings of our bodies from the perspective of a surgeon. Dr. Nuland recounts age-old legends about the functions and "personalities" of the body's organs and, in riveting vignettes of the surgery he has performed, he describes the connections between myth and reality. A brilliant blend of science and folklore, The Mysteries Within reveals the enigmas not only of the body but also of the human imagination.

    Key Features: The Author Uses A Reader-Friendly, Narrative Style Making The Text Engaging And Accessible To A Broad Range Of Students. The Text Illustrates The Multidisciplinary Nature Of Public Health And The Complex Ethical And Political Issues Central To It. It Includes Discussions Of Epidemiological Investigation, Biomedical Research, Environmental Assessment, Analyses Of Individual And Group Behavior, Massive Data Collection Efforts, And Policy Developments. New To This Edition: New Discussions About U.S. Health Care Reform New Discussions Of The Globalization Of National Economies And Its Effect On The Health Of Populations Expanded Discussions On Health Disparities New Analysis Of What Went Wrong Just After Hurricane Katrina Updated Discussions Of Developments In Topics Such Are H1N1 Swine Flu, Hormone Replacement Therapy, FDA Regulation, HPV Vaccine Controversy Planning For Healthy People 2020 And Much More.

    PCOS is by far the most common hormone imbalance in women of this age group, yet few women understand the threat it poses to their health—or how to prevent it. In A Patient's Guide to PCOS, Dr. Walter Futterweit, a foremost authority on PCOS in America, tells women everything they need to know about this condition and how to treat it. Drawing on his twenty-five years researching and treating the condition and his ongoing long-term study of more than a thousand women with PCOS, Futterweit discusses• what PCOS is and how it affects your body• what to eat and how to exercise to control PCOS• all the treatment options, including the latest drug therapies• how to reverse PCOS-induced infertility and restore healthy skin and hair• resources for preventing, diagnosing, and treating PCOSThis comprehensive guide contains everything women need to know about PCOS—from identifying warning signs and seeking a diagnosis to finding emotional support in recovery—to regain their health and resume their lives.

    This trusted classic delivers comprehensive coverage of the field's must-know basic science and clinical topics in a clear, easy-to-understand presentation. Indispensable for coursework, exam review, and as a clinical refresher, this trusted text has been extensively updated to reflect the latest research and developments.Here's why Clinical Anesthesiology is the best anesthesiology resource:NEW full-color presentationNEW chapters on the most pertinent topics in anesthesiology, including anesthesia outside of the operating room and a revamped peripheral nerve blocks chapter that details ultrasound-guided regional anesthesiaUp-to-date discussion of all relevant areas within anesthesiology, including equipment, pharmacology, regional anesthesia, pathophysiology, pain management, and critical careCase discussions promote application of the concepts to real-world practiceNumerous tables and figures encapsulate important information and facilitate memorization

    To meet it, you need a fully integrated text and supplements package that sets the stage for a perfectly choreographed learning experience.

    "The London, Upton, Stone series has helped over 1,000,000 photography students capture their potential. After a very successful first edition, this second edition returns with the most up-to-date industry knowledge. Modeled after the long-running and widely used "A ""Short Course in Photography, " a brief text which presents the medium entirely in its most updated form.

    This guidebook is aimed clearly at the needs of the student, with a thorough understanding of, and provision for, the potential conceptual difficulties he or she is likely to encounter.

    Highlights of this edition include a brief glossary of key neuroanatomical structures and disease states; addition of an icon to more clearly identify the Clinical Correlations sections; an appendicized table of common neurological lesions; expanded figure legends that identify clinically relevant anatomical relationships; an improved, expanded index; and modified text and figure legends to comply with Terminologia Anatomica.A companion Website will offer bonus USMLE-style questions.

    This book teaches you how to conduct examinations by explaining what digital forensics is, the methodologies used, key technical concepts and the tools needed to perform examinations. Details on digital forensics for computers, networks, cell phones, GPS, the cloud, and Internet are discussed. Readers will also learn how to collect evidence, document the scene, and recover deleted data. This is the only resource your students need to get a jump-start into digital forensics investigations.This book is organized into 11 chapters. After an introduction to the basics of digital forensics, the book proceeds with a discussion of key technical concepts. Succeeding chapters cover labs and tools; collecting evidence; Windows system artifacts; anti-forensics; Internet and email; network forensics; and mobile device forensics. The book concludes by outlining challenges and concerns associated with digital forensics. PowerPoint lecture slides are also available.This book will be a valuable resource for entry-level digital forensics professionals as well as those in complimentary fields including law enforcement, legal, and general information security.

    The clarity of discussion and tight organization of material simplify the study of this broad and diverse subject. Covers all aspects of the introductory course.