The latest edition offers greatly expanded coverage of directed mutagenesis and protein engineering, therapeutic agents, and genetic engineering of plants. Updated chapters reflect recent developments in biotechnology and the societal issues related to it, such as cloning, gene therapy, and patenting and releasing genetically engineered organisms. Over 480 figures, including 200 that are new in this edition, illustrate all key concepts. "Milestones" summarize important research papers in the history of biotechnology and their effects on the field. As in previous editions, the authors clearly explain all concepts and techniques to provide maximum understanding of the subject, avoiding confusing scientific jargon and excessive detail wherever possible. Each chapter concludes with a summary, references, and review questions. Ideally suited as a text for third- and fourth-year undergraduates as well as graduate students, this book is also an excellent reference for health professionals, scientists, engineers, or attorneys interested in biotechnology.

    Danielle Martin sees the challenges in our health care system every day. As a family doctor and a hospital vice president, she observes how those deficiencies adversely affect patients. And as a health policy expert, she knows how to close those gaps. A passionate believer in the value of fairness that underpins the Canadian health care system, Dr. Martin is on a mission to improve medicare. In Better Now, she shows how bold fixes are both achievable and affordable. Her patients' stories and her own family's experiences illustrate the evidence she presents about what works best to improve health care for all.Better Now outlines "Six Big Ideas" to bolster Canada's health care system. Each one is centred on a typical Canadian patient, making it clear how close to home these issues strike.- Ensure every Canadian has regular access to a family doctor or other primary care provider- Bring prescription drugs under medicare- Reduce unnecessary tests and interventions- Reorganize health care delivery to reduce wait times and improve quality- Implement a basic income guarantee to alleviate poverty, which is a major threat to health- Scale up successful local innovations to a national levelPassionate, accessible, and authoritative, Dr. Martin is a fervent supporter of the best of medicare and a persuasive critic of what needs fixing.

    As a result, Glass Half Full has undergone a revamp including a professional edit, added photographs from our journey and a professional book cover. I hope you enjoy the changes. Is the glass half-empty or half-full? Ironically, sometimes life influences our view and alters our perception. Life changing events, up to 1997 almost destroyed me. At my lowest point, and just in time, I met Nigel. He helped me to discover how a positive attitude can change everything. I decided not to squander any more of my time or energy on undeserving people. This new positive approach helps me to perceive my glass as half-full, with my aim being to achieve a happy and healthy life for my family. Together, we live life to the full. In 2008, with good times ahead of us, my glass was half-full. As a family, we made the biggest and most difficult decision of our lives; part of our family would emigrate to Australia. We lived the Australian dream, embracing the adventure until adversity came to test us. A sequence of life changing events including a close family bereavement, PTSD (Post Traumatic Stress Disorder) following a road rage car accident and the shock of losing the roots to our Australian adventure as a result of the Brisbane floods tested us on many levels. Glass Half Full follows our journey into happy, sad and challenging times.Find out what it takes to survive with the odds stacked against you. Do you fight back, and if so, at what cost physically and emotionally? Could we maintain our positivity and family values against the odds? This is our story.

    One heart. Two eyes. Ten fingers. You may think you know what makes up a human. But it turns out our bodies are full of surprises. What makes tears of joy different from tears of sadness?Why is a gut feeling so much smarter than you think?And why is 90% of you not even human?You may think you know the human body – heart, lungs, brain and bones – but your body is full of extraordinary mysteries that science is only just beginning to understand. This book, which accompanies a major new BBC TV programme, will change the way we think about our bodies.Doctors are in the business of keeping secrets, but medical confidentiality isn’t just about privacy, shame or discretion. It’s about vulnerability to exploitation. In this ground-breaking new book, the effervescent van Tulleken twins bring their knowledge and charm to the page to reveal just how well our bodies keep secrets from the things that want to exploit it: bacteria, viruses, fungi, parasites, larger predators and, crucially, other people. They uncover the remarkable stories behind the science we are not meant to know, on matters of life and death.Leading us through these revelations are tales of everyday miracles – the human stories that bind every one of us together through the universal stages of life. From the most extreme environments on Earth to the most extreme events, Chris and Xand reveal the incredible abilities every human shares. Arranged around the three themes of learning, survival and growth, this book shows the human body like never before.Combining cutting-edge science and technology with stunning photography that gives us a tantalising glimpse beneath our skin, the van Tullekens reveal the secrets that make very ordinary human body … extraordinary.

    if Fast Food Nation made you consider some serious lifestyle changes, The Hundred-Year Lie will inspire you to go ten steps farther." -- Boston HeraldCombining the impact of the classic bestseller Silent Spring with Fast Food Nation, The Hundred-Year Lie: How Food and Medicine Are Destroying Your Health presents a devastating exposé of how chemicals in everyday products are ruining our health. Over the past one hundred years, we have been guinea pigs in a vast chemistry experiment that uses our bodies, our health, and our good will to test the proposition that modern science can improve upon nature. In The Hundred-Year Lie, investigative journalist RandallFitzgerald shatters dozens of myths being perpetuated by the chemical, pharmaceutical and processed food industries. Find out why you would never be FDA-approved—and why humans are becoming one of the most polluted species on the planet: • The average American now carries a “body burden” of 700 or more synthetic chemicals, including Teflon, plastics, and dozens of pesticides. • Musk fragrances used in detergents and air fresheners are not filtered out by our current water treatment facilities, ending up in our drinking water. • The artificial sweetener aspartame, an ingredient in 1,200 food products from diet drinks to chewing gum, has been linked to eighty-eight toxic symptoms. Fitzgerald not only sheds light on the problems we face from the unprecedented chemical onslaught, he presents suggestions for what we can to do to turn the tide.

    Whether you work in emergency medicine, or just want to be prepared, this book will be your essential guide.Following the latest clinical guidelines and evidence, written and reviewed by experts, this handbook will ensure you are up-to-date and have the confidence to deal with all emergency presentations, practices, and procedures. Following the latest developments in the field, such as infection control, DNR orders, advanced directives and learning disability. The book also includes new sections specifically outlining patient advice and information, as well as new and revised vital information on paediatrics and psychiatry. For all junior doctors, specialist nurses, paramedics, clinical students, GPs and other allied health professionals, this rapid-reference handbook will become a vital companion for both study and practice.

    It affects 81 million Americans and is the culprit in one of every two deaths in the United States. Most people think that they are not at risk of a heart attack if they control their cholesterol and blood pressure, but they aren’t aware of other major risk factors. The good news is that with the right information and strategies, heart attacks are preventable—even if heart disease runs in the family. In Beat the Heart Attack Gene, world-renowned cardiovascular specialists Bradley Bale, MD and Amy Doneen, ARNP, present a new model for understanding and preventing heart disease. They explain the three different genetic types of cholesterol profiles and tailor treatments for each type, using their cutting-edge Bale/Doneen Method, a simple, comprehensive prevention plan that detects cardiovascular disease (CVD) at early stages. Beat the Heart Attack Gene includes easy quizzes and self-tests that show how to determine cholesterol genotype as well as advice for how to apply that knowledge through nutritional and lifestyle changes. For heart attack and stroke survivors, the Bale/Doneen Method also helps prevent recurrences by identifying and treating what's triggering the patient's disease—a crucial step that many cardiologists neglect. With their proven method utilized by healthcare professionals worldwide, Bale and Doneen empower readers by alerting them to potential health threats, and then offer personalized, evidence-based strategies so they can live healthy, active lives without fear of heart attack or stroke. Specifically, Beat the Heart Attack Gene addresses: *The hidden cause of most heart attacks *Early prevention methods *The dangerous cholesterol most doctors don’t check *Major red flags for heart attack and stroke risk, including gum disease *The gene that increases cardiovascular risk as much as smoking *The best and worst supplements for your heart *10 surprising ways to prevent heart attacks

    The 4th Edition of this bestseller has been completely revised and reorganized to present a more up-to-date approach to the field, with less emphasis on traditional hospital-based practice. It uses the APGO/CREOG curriculum objectives as a framework, with a special emphasis on women's health issues. A new, full-color design with many illustrations and photographs complements the text. Plus, a free downloadable PDA software program provides a complete guide to the most common disorders. The smart way to study Elsevier titles STUDENT CONSULT will help you master difficult concepts and study more efficiently in print and online Perform rapid searches. Integrate bonus content from other disciplines. Download text to your handheld device. And a lot more. Each STUDENT CONSULT title comes with full text online, a unique image library, case studies, USMLE style questions, and online note-taking to enhance your learning experience.

    It includes a concise, A-Z organization of the drugs, and includes information on 21 newly-approved drugs. More than 1,300 generic drugs and 4,500 trade names are included, as are over 800 new nursing guidelines.

    We all have one, but most of us will never see one. The heart surgeon now has that privilege but, for centuries, the heart was out of reach even for surgeons. So when a surgeon nowadays opens up a ribcage and mends a heart, it remains something of a miracle, even if, to some, it is merely plumbing. As with plumbers, the quality of surgeons’ work varies. As with plumbers, surgeons’ opinion of their own prowess and their own attitude to risk are not always reliable. Measurement is key. We’ve had a century of effective evidence-based medicine. We’ve had barely a decade of thorough monitoring of clinical outcomes. Thanks to the ground-breaking risk modelling of pioneering surgeons like Samer Nashef, we at last know how to judge whether an operation is in a patient’s best interest, which hospital and surgeon would be best for that operation, when it might best be performed and what the exact level of risk is. We have at last made what is important in surgery measurable. But how should surgeons, and their patients, use these newfound insights? Ever since his days as a medical student, Samer Nashef has challenged the medical profession to be more open and more accurate about the success of surgical procedures, for the sake of the patients. In The Naked Surgeon, he unclothes his own profession to demonstrate to his reader (and prospective patient) many revelations, such as the paradox at the heart of the cardiac surgeon’s craft: the more an operation is likely to kill you, the better it is for you. And he does so with absolute clarity, fluency and not a little wit.

    At his death last spring, Roueche left behind seven new narratives that have never been published in book form. This book collects these works along with one earlier classic--all relating true tales of strange illnesses, rare diseases, and the brilliant minds who race to understand and conquer them.

    But you can't choose what you have... can you? Desire soon turns to obsession as Charlotte embarks on a difficult and controversial journey to sway the odds to have a girl. How far is she prepared to go, and at what cost?

    She is auditioning for Julliard and he has offers for soccer scholarships at any school he wants. Only Isabelle knew he was planning to put off college and join the Army. Tragedy strikes one day and Ian is killed. In her grief, Isabelle decides to put her dream on hold and honor his. While deployed tragedy strikes again and she is injured. Thinking her dreams of dancing again are out of reach she gives up on life. Is she strong enough to overcome her disabilities? Can the love she finds with her brothers best friend Conner be enough to help her reclaim her dreams?

    Edited by Drs. Karen Marcdante, Robert M. Kliegman, Hal B. Jenson, and Richard E. Behrman, this edition's content was specifically developed in accordance with the 2009 curriculum guidelines of the Council on Medical Student Education in Pediatrics. It also includes many new and improved clinical photographs and images for enhanced visual reference. A user-friendly full-color format and online access via Student Consult facilitate study and expedite reference.

    Public access to institutions for the insane. And full-blown surgeries without the aid of anesthetics or painkillers. Welcome to the middle ages of American medicine. Bleed, Blister, Puke, and Purge exposes the extraordinary practices and major players of American medical history, from the colonial era to the late 1800s. It’s hard to believe that today’s cutting-edge medicine originated from such crude beginnings, but this book reminds us to be grateful for today’s medical care, while also raising the question: what current medical practices will be the horrors of tomorrow?