Armstrong writes about her experience as one of only a few people to participate in an experimental treatment for depression involving ten rounds of a chemically induced coma approximating brain death.For years, Heather B. Armstrong has alluded to her struggle with depression on her website. But in 2016, Heather found herself in the depths of a depression she just couldn’t shake, an episode darker and longer than anything she had previously experienced. This book recalls the torturous eighteen months of suicidal depression she endured and the month-long experimental study in which doctors used propofol anesthesia to quiet all brain activity for a full fifteen minutes before bringing her back from a flatline. Ten times. The experience wasn’t easy. Not for Heather or her family. But a switch was flipped, and Heather hasn’t experienced a single moment of suicidal depression since. The Valedictorian of Being Dead brings to light a groundbreaking new treatment for depression.

    MacLeod and her husband encountered their dream while vacationing on a remote island in the Scottish Hebrides. Enthralled by its windswept beauty, they soon were the proud owners of a near-derelict croft house--a farmer's stone cottage--on "a small acre" of land. Mary assumed duties as the island's district nurse. Call the Nurse is her account of the enchanted years she and her family spent there, coming to know its folk as both patients and friends.In anecdotes that are by turns funny, sad, moving, and tragic, she recalls them all, the crofters and their laird, the boatmen and tradesmen, young lovers and forbidding churchmen. Against the old-fashioned island culture and the grandeur of mountain and sea unfold indelible stories: a young woman carried through snow for airlift to the hospital; a rescue by boat; the marriage of a gentle giant and the island beauty; a ghostly encounter; the shocking discovery of a woman in chains; the flames of a heather fire at night; an unexploded bomb from World War II; and the joyful, tipsy celebration of a ceilidh. Gaelic fortitude meets a nurse's compassion in these wonderful true stories from rural Scotland.

    The race to catch him would give birth to a new science called criminal profiling.Grand Central, Penn Station, Radio City Music Hall―for almost two decades, no place was safe from the man who signed his anonymous letters “FP” and left his lethal devices in phone booths, storage lockers, even tucked into the plush seats of movie theaters. His victims were left cruelly maimed. Tabloids called him “the greatest individual menace New York City ever faced.”In desperation, Police Captain Howard Finney sought the help of a little known psychiatrist, Dr. James Brussel, whose expertise was the criminal mind. Examining crime scene evidence and the strange wording in the bomber’s letters, he compiled a portrait of the suspect down to the cut of his jacket. But how to put a name to the description? Seymour Berkson―a handsome New York socialite, protégé of William Randolph Hearst, and publisher of the tabloid The Journal-American―joined in pursuit of the Mad Bomber. The three men hatched a brilliant scheme to catch him at his own game. Together, they would capture a monster and change the face of American law enforcement.

    Nathan Leopold and Richard Loeb were intellectual--too smart, they believed, for the police to catch them. When they were apprehended, state's attorney Robert Crowe was certain that no defense could save the ruthless killers from the gallows. But the families of the confessed murderers hired Clarence Darrow, entrusting the lives of their sons to the most famous lawyer in America in what would be one of the most sensational criminal trials in the history of American justice.Set against the backdrop of the 1920s--a time of prosperity, self-indulgence, and hedonistic excess in a lawless city on the brink of anarchy—For the Thrill of It draws the reader into a world of speakeasies and flappers, of gangsters and gin parties, with a spellbinding narrative of Jazz Age murder and mystery.

    B. West, chief usher of the White House, directed the operations and maintenance of 1600 Pennsylvania Avenue—and coordinated its daily life—at the request of the president and his family. He directed state functions; planned parties, weddings and funerals, gardens and playgrounds, and extensive renovations; and with a large staff, supervised every activity in the presidential home. For twenty-eight years, first as assistant to the chief usher, then as chief usher, he witnessed national crises and triumphs, and interacted daily with six consecutive presidents and first ladies, their parents, children and grandchildren, and houseguests—including friends, relatives, and heads of state.In Upstairs at the White House, West offers an absorbing and novel glimpse at America’s first families, from the Roosevelts to the Kennedys andthe Nixons. Alive with anecdotes ranging from the quotidian (Lyndon B. Johnson’s showerheads) to the tragic (the aftermath of John F. Kennedy’s assassination), West’s book is an enlightening and rich account of the American history that took place just behind the Palladian doors of the North Portico.

    When a small vial arrives in her mailbox from "Lewis Carroll," Ayelet Waldman is at a low point. Her mood storms have become intolerably severe; she has tried nearly every medication possible; her husband and children are suffering with her. So she opens the vial, places two drops on her tongue, and joins the ranks of an underground but increasingly vocal group of scientists and civilians successfully using therapeutic microdoses of LSD. As Waldman charts her experience over the course of a month--bursts of productivity, sleepless nights, a newfound sense of equanimity--she also explores the history and mythology of LSD, the cutting-edge research into the drug, and the byzantine policies that control it. Drawing on her experience as a federal public defender, and as the mother of teenagers, and her research into the therapeutic value of psychedelics, Waldman has produced a book that is eye-opening, often hilarious, and utterly enthralling.

    In January's case, she is hallucinating 95 percent of the time that she is awake. Potent psychiatric drugs that would level most adults barely faze her. January, "Jani" to her family, has literally hundreds of imaginary friends. They go by names like 400-the-Cat, 100 Degrees, and 24 Hours and live on an island called "Calalini," which she describes as existing "on the border of my world and your world." Some of these friends are good, and some of them, such as 400, are very bad. They tell her to jump off buildings, attack her brother, and scream at strangers.In the middle of these never-ending delusions, hallucinations, and paroxysms of rage are Jani's parents, who have gone to the ends of the earth to keep both of their children alive and unharmed. They live in separate one-bedroom apartments in order to keep her little brother, Bohdi, safe from his big sister—and wage a daily war against a social system that has all but completely failed them. January First is the story of the daily struggles and challenges they face as they do everything they can to help their daughter while trying to keep their family together. It is the inspiring tale of their resolute determination and faith.

    From distressed small communities in Central Appalachia to wealthy suburbs; from disparate cities to once-idyllic farm towns; it's a heartbreaking trajectory that illustrates how this national crisis has persisted for so long and become so firmly entrenched. Beginning with a single dealer who lands in a small Virginia town and sets about turning high school football stars into heroin overdose statistics, Macy endeavors to answer a grieving mother's question-why her only son died-and comes away with a harrowing story of greed and need. From the introduction of OxyContin in 1996, Macy parses how America embraced a medical culture where overtreatment with painkillers became the norm. In some of the same distressed communities featured in her bestselling book Factory Man, the unemployed use painkillers both to numb the pain of joblessness and pay their bills, while privileged teens trade pills in cul-de-sacs, and even high school standouts fall prey to prostitution, jail, and death.Through unsparing, yet deeply human portraits of the families and first responders struggling to ameliorate this epidemic, each facet of the crisis comes into focus. In these politically fragmented times, Beth Macy shows, astonishingly, that the only thing that unites Americans across geographic and class lines is opioid drug abuse. But in a country unable to provide basic healthcare for all, Macy still finds reason to hope-and signs of the spirit and tenacity necessary in those facing addiction to build a better future for themselves and their families.

    Operating in Chicago’s notorious Levee district at the dawn of the last century, the Club’s proprietors, two aristocratic sisters named Minna and Ada Everleigh, welcomed moguls and actors, senators and athletes, foreign dignitaries and literary icons, into their stately double mansion, where thirty stunning Everleigh “butterflies” awaited their arrival. Courtesans named Doll, Suzy Poon Tang, and Brick Top devoured raw meat to the delight of Prince Henry of Prussia and recited poetry for Theodore Dreiser. Whereas lesser madams pocketed most of a harlot’s earnings and kept a “whipper” on staff to mete out discipline, the Everleighs made sure their girls dined on gourmet food, were examined by an honest physician, and even tutored in the literature of Balzac.Not everyone appreciated the sisters’ attempts to elevate the industry. Rival Levee madams hatched numerous schemes to ruin the Everleighs, including an attempt to frame them for the death of department store heir Marshall Field, Jr. But the sisters’ most daunting foes were the Progressive Era reformers, who sent the entire country into a frenzy with lurid tales of “white slavery-the allegedly rampant practice of kidnapping young girls and forcing them into brothels. This furor shaped America’s sexual culture and had repercussions all the way to the White House, including the formation of the Federal Bureau of Investigation.With a cast of characters that includes Jack Johnson, John Barrymore, John D. Rockefeller, Jr., William Howard Taft, “Hinky Dink” Kenna, and Al Capone, Sin in the Second City is Karen Abbott’s colorful, nuanced portrait of the iconic Everleigh sisters, their world-famous Club, and the perennial clash between our nation’s hedonistic impulses and Puritanical roots. Culminating in a dramatic last stand between brothel keepers and crusading reformers, Sin in the Second City offers a vivid snapshot of America’s journey from Victorian-era propriety to twentieth-century modernity.

     Giving shape to the deep depression that pervaded Lincoln's adult life, Joshua Wolf Shenk's Lincoln's Melancholy reveals how this illness influenced both the president's character and his leadership. Lincoln forged a hard path toward mental health from the time he was a young man. Shenk draws from historical record, interviews with Lincoln scholars, and contemporary research on depression to understand the nature of his unhappiness. In the process, he discovers that the President's coping strategies—among them, a rich sense of humor and a tendency toward quiet reflection—ultimately helped him to lead the nation through its greatest turmoil.

    The Sackler name adorns the walls of many storied institutions: Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, known for their lavish donations to the arts and sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing OxyContin, a blockbuster painkiller that was a catalyst for the opioid crisis.Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling.

    From a fortress-like former bank building, American Pain's doctors distributed massive quantities of oxycodone to hundreds of customers a day, mostly traffickers and addicts who came by the vanload. Inked muscle-heads ran the clinic's security. Former strippers operated the pharmacy, counting out pills and stashing cash in garbage bags. Under their lab coats, the doctors carried guns and it was all legal sort of. American Pain was the brainchild of Chris George, a 27-year-old convicted drug felon. The son of a South Florida home builder, Chris George grew up in ultra-rich Wellington, where Bill Gates, Springsteen, and Madonna kept houses. Thick-necked from weightlifting, he and his twin brother hung out with mobsters, invested in strip clubs, brawled with cops, and grinned for their mug shots. After the housing market stalled, a local doctor clued in the brothers to the burgeoning underground market for lightly regulated prescription painkillers. In Florida, pain clinics could dispense the meds, and no one tracked the patients. Seizing the opportunity, Chris George teamed up with the doctor, and word got out. Just two years later Chris had raked in $40 million, and 90 percent of the pills his doctors prescribed flowed north to feed the rest of the country's insatiable narcotics addiction. Meanwhile, hundreds more pain clinics in the mold of American Pain had popped up in the Sunshine State, creating a gigantic new drug industry. American Pain chronicles the rise and fall of this game-changing pill mill, and how it helped tip the nation into its current opioid crisis, the deadliest drug epidemic in American history. The narrative swings back and forth between Florida and Kentucky, and is populated by a gaudy and diverse cast of characters. This includes the incongruous band of wealthy bad boys, thugs and esteemed physicians who built American Pain, as well as penniless Kentucky clans who transformed themselves into painkiller trafficking rings. It includes addicts whose lives were devastated by American Pain's drugs, and the federal agents and grieving mothers who labored for years to bring the clinic's crew to justice."

    Parents and family members who never thought they could get inside the head of their autistic loved one, at last, have a way to break through to the curious, subtle, and complex life within.Using an alphabet grid to painstakingly construct words, sentences, and thoughts that he is unable to speak out loud, Naoki answers even the most delicate questions that people want to know. Questions such as: “Why do people with autism talk so loudly and weirdly?” “Why do you line up your toy cars and blocks?” “Why don’t you make eye contact when you’re talking?” and “What’s the reason you jump?” (Naoki’s answer: “When I’m jumping, it’s as if my feelings are going upward to the sky.”) With disarming honesty and a generous heart, Naoki shares his unique point of view on not only autism but life itself. His insights—into the mystery of words, the wonders of laughter, and the elusiveness of memory—are so startling, so strange, and so powerful that you will never look at the world the same way again.

    Or the "Phantom of Fine Hall," a figure many students had seen shuffling around the corridors of the math and physics building wearing purple sneakers and writing numerology treatises on the blackboards. The Phantom was John Nash, one of the most brilliant mathematicians of his generation, who had spiraled into schizophrenia in the 1950s. His most important work had been in game theory, which by the 1980s was underpinning a large part of economics. When the Nobel Prize committee began debating a prize for game theory, Nash's name inevitably came up—only to be dismissed, since the prize clearly could not go to a madman. But in 1994 Nash, in remission from schizophrenia, shared the Nobel Prize in economics for work done some 45 years previously.Economist and journalist Sylvia Nasar has written a biography of Nash that looks at all sides of his life. She gives an intelligent, understandable exposition of his mathematical ideas and a picture of schizophrenia that is evocative but decidedly unromantic. Her story of the machinations behind Nash's Nobel is fascinating and one of very few such accounts available in print (the CIA could learn a thing or two from the Nobel committees).

     A riveting, powerful telling of the story of the grassroots movement of activists, many of them in a life-or-death struggle, who seized upon scientific research to help develop the drugs that turned HIV from a mostly fatal infection to a manageable disease. Ignored by public officials, religious leaders, and the nation at large, and confronted with shame and hatred, this small group of men and women chose to fight for their right to live by educating themselves and demanding to become full partners in the race for effective treatments. Around the globe, 16 million people are alive today thanks to their efforts. Not since the publication of Randy Shilts's classic And the Band Played On has a book measured the AIDS plague in such brutally human, intimate, and soaring terms. In dramatic fashion, we witness the founding of ACT UP and TAG (Treatment Action Group), and the rise of an underground drug market in opposition to the prohibitively expensive (and sometimes toxic) AZT. We watch as these activists learn to become their own researchers, lobbyists, drug smugglers, and clinicians, establishing their own newspapers, research journals, and laboratories, and as they go on to force reform in the nation s disease-fighting agencies. With his unparalleled access to this community David France illuminates the lives of extraordinary characters, including the closeted Wall Street trader-turned-activist, the high school dropout who found purpose battling pharmaceutical giants in New York, the South African physician who helped establish the first officially recognized buyers club at the height of the epidemic, and the public relations executive fighting to save his own life for the sake of his young daughter. Expansive yet richly detailed, this is an insider's account of a pivotal moment in the history of American civil rights. Powerful, heart-wrenching, and finally exhilarating, How to Survive a Plague is destined to become an essential part of the literature of AIDS.