The Grand Question of Lifes Origins 2. The Historical Setting of Origins Research 3. What Is Life? 4. Is There Life on Mars? 5. Earths Oldest Fossils 6. Fossil Isotopes 7. Molecular Biosignatures 8. Emergence 9. The Miller-Urey Experiment 10. Life from the Bottom of the Sea 11. The Deep, Hot Biosphere 12. Experiments at High Pressure 13. More Experiments Under Pressure 14. Deep Space Dust, Molten Rock, and Zeolite 15. Macromolecules and the Tree of Life 16. Lipids and Membrane Self-Organization 17. Life on Clay, Clay as Life 18. Lifes Curious Handedness 19. Self-Replicating Molecular Systems 20. Günter Wächtershäusers Grand Hypothesis 21. The RNA World 22. The Pre-RNA World 23. Natural Selection and Competition 24. Three Scenarios for the Origin of Life

    What makes evolution such a profoundly provocative concept, so convincing to most scientists, yet so socially and politically divisive? The Theory of Evolution: A History of Controversy is an examination of the varied elements that so often make this science the object of strong sentiments and heated debate. Professor Edward J. Larson leads you through the "evolution" of evolution, with an eye toward enhancing your understanding of the development of the theory itself and the roots of the controversies that surround it. In these lectures you will: Explore pre-Darwinian theories of the origins of life, from Genesis and the ancient Greeks to such 18th- and 19th-century scientists as Georges Cuvier and Chevalier de Lamarck Follow the life and work of Charles Darwin, and the impact of his 1859 masterpiece, On the Origin of Species. Darwin's theory of evolution by natural selection was immediately recognized as a threat to traditional religion, but was quickly accepted (the first printing of Origin of Species sold out on the first day) Examine the history of evolutionary science after Darwin-a fascinating story that includes the "rediscovery," after 35 years, of Gregor Mendel's work on genetic variation; the unearthing of prehominid, or early human, fossils by Raymond Dart in 1925 and the Leakey family in the 1950s; and the confusion created by the sensational, but later discredited, discovery of Piltdown Man-a fake evolutionary "missing link"-in 1912 Trace the history of religious objections to evolution, from those of Darwin's own time to contemporary efforts to teach creation science in American schools. This includes a detailed discussion of the famous Scopes "monkey trial," which in fact was a staged media event, designed to create publicity for the town of Dayton, Tennessee. Are Our Genes more Important than We Are? This course makes it clear that the history of controversy surrounding evolution is not limited to a dispute between science and religion. Even within the scientific community, the fine details of the theory of evolution have long been a matter of passionate dispute. In fact, in the last third of the 19th century, the principal objections were scientific, not religious. Although the fossil record was a key piece of evidence for evolution, it had gaps that could be used to argue against the theory. And both proponents and critics wondered how altruistic human qualities such as love and generosity could possibly have evolved through the competitive, often harsh, processes that Darwin described. From Professor Larson's presentation, you will learn that new ideas in evolution science have often created new controversies. For example, is it truly possible, as some scientists now maintain, that humans exist merely to ensure the survival of their genes? Such research has created disagreement among scientists about the degree to which evolution drives human behavior, and has further alienated many segments of the public. Evolution's "Dark Side": Social Darwinism In these lectures, you will review perhaps the most sinister controversy associated with the theory of evolution: social Darwinism. From the beginning, the Darwinian theory of evolution has been linked to economic and political views. Thomas Malthus's theories of population growth and competition for limited resources even inspired Darwin's thinking on natural selection. Unfortunately, later supporters of evolution carried this line of thinking too far. Beginning with Herbert Spencer, who coined the term "survival of the fittest," Darwin's ideas were used as evidence for a wide range of social beliefs, from laissez-faire capitalism to racism, colonialism, and, in perhaps the worst application, Nazism. In the United States, social Darwinism has served as a basis for the creation of IQ tests and for eugenics programs that resulted in the forced sterilization of thousands of mentally ill or retarded Americans. Unsettling Implications: The Growing Gulf Between Science and Religion During the late 19th century, largely through the efforts of scientists who sought to integrate evolutionary science with spiritual belief, evolution was widely accepted by the religious community in the United States. Today, this is hardly the case. In his last four lectures, Professor Larson examines the trends that have, since 1920, widened the gulf between science and religion. These include an increase in fundamentalist Protestantism, the weakening of liberal Protestantism as a counteracting force, and the growing power of a firmly conservative South. In the 1960s, federally funded neo-Darwinian textbooks provoked a conservative backlash. Beginning with the publication of Henry M. Morris's The Genesis Flood, efforts to gain equal time for the teaching of creation science, based on biblical teachings, gathered strength. Rebuffed by the courts, creationism continues to thrive through the increasing numbers of private Christian schools and through home schooling. The growing gulf between science and religion has unsettling implications for our society. Large segments of the American population reject the naturalism of current evolutionary thinking. Nine of 10 Americans believe in spiritual causes for life, with only 10 percent accepting the purely naturalistic explanations espoused by evolution. Strikingly, these statistics are almost exactly the opposite among the scientific community. A Pulitzer Prize-Winning Teacher As both a historian of science and a professor of law, Professor Edward J. Larson brings exceptional qualifications to this subject. His book, Summer for the Gods: The Scopes Trial and America's Continuing Debate Over Science and Religion, won the 1998 Pulitzer Prize in History. His analysis provides an invaluable perspective on the volatile history of what is arguably the single most significant idea of modern times.

    One of the first paleoanthropologists to study fossil evidence and genetic information together in order to test hypotheses about human prehistory, Professor Hawks is adept at looking at human origins not just with one lens, but with two.He has traveled around the world to examine delicate skeletal remains and pore over the complex results of genetic testing. His research and scholarship on human evolutionary history has been featured in a variety of publications, including Science, American Journal of Physical Anthropology, Slate, and Journal of Human Evolution.But more than that, Professor Hawks has crafted a course that demonstrates the passion and excitement involved in the field of paleoanthropology. With his engaging lecturing style and his use of fossil finds taken from his personal collection, Professor Hawks will capture your attention and show you all the drama and excitement to be found in eavesdropping on the latest debates about human evolutionary history.

    Yet, as the 1700s began, the mysteries of the universe were pondered by "natural philosophers"—the term "scientist" didn't even exist until the mid 19th century—whose explanations couldn't help but be influenced by the religious thought and political and social contexts that shaped their world.The radical ideas of the Enlightenment were especially important and influential. In this course you see how the work of these natural philosophers prepared the way for the more familiar world of science we recognize today.

    Two scientists explore the potential of a revolutionary genetics technology capable of easily and affordably manipulating DNA in human embryos to prevent specific diseases, addressing key concerns about related ethical and societal repercussions.

    And you'll also learn the "rules of the game" - the forces that drive those particles and the ways in which they interact - that underlie the workings of the universe.The lectures have been designed to be enriching for everyone, regardless of scientific background or mathematical ability. Virtually all you'll need as you enter this fascinating world are your curiosity, common sense, and, as Professor Pollock notes, "an open mind for the occasional quantum weirdness." As you move through the lectures, you'll also gain a knowledge of how those particles fit into perhaps the greatest scientific theory of all time: the Standard Model of particle physics; a grasp of key terms like "gauge symmetry," "quantum chromodynamics," and "unified quantum field Theory;" and an appreciation of how particle physics fits in with other branches of physics - including cosmology and quantum mechanics - to create our overall understanding of nature.

    Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities. . . .But, Zimmer writes, "Each of us carries an amalgam of fragments of DNA, stitched together from some of our many ancestors. Each piece has its own ancestry, traveling a different path back through human history. A particular fragment may sometimes be cause for worry, but most of our DNA influences who we are--our appearance, our height, our penchants--in inconceivably subtle ways." Heredity isn't just about genes that pass from parent to child. Heredity continues within our own bodies, as a single cell gives rise to trillions of cells that make up our bodies. We say we inherit genes from our ancestors--using a word that once referred to kingdoms and estates--but we inherit other things that matter as much or more to our lives, from microbes to technologies we use to make life more comfortable. We need a new definition of what heredity is and, through Carl Zimmer's lucid exposition and storytelling, this resounding tour de force delivers it. Weaving historical and current scientific research, his own experience with his two daughters, and the kind of original reporting expected of one of the world's best science journalists, Zimmer ultimately unpacks urgent bioethical quandaries arising from new biomedical technologies, but also long-standing presumptions about who we really are and what we can pass on to future generations.

    From the rising and setting of the sun to the cycles of nature, the thought processes in our brains, and the biorhythms in our day, nothing so pervades our existence and yet is so difficult to explain. Time seems to be woven into the very fabric of the universe. But why? Consider these contrasting views of time: A movie of a person diving into a pool has an obvious arrow of time. When the movie is played backward, everyone recognizes that it shows an event that would never occur in the real world. But zoom in on any part of this scene at the atomic scale and the movie can be run backward or forward and be indistinguishable. Either way, the particle interactions are consistent with the laws of physics. Why does one movie have an arrow of time moving in only one direction and the other does not? Surprisingly, the search for an answer leads through some of the most pioneering fields of physics, including thermodynamics, relativity, quantum theory, and cosmology. The key concept is called "entropy," which is related to the second law of thermodynamics, considered by many scientists to be the most secure law in all of physics. But that's only the beginning, since the quest for the ultimate theory of time draws on such exciting ideas as black holes, cosmic inflation, and dark energy, before closing in on a momentous question that until recently was considered unanswerable: What happened before the big bang? In 24 riveting half-hour lectures, Mysteries of Modern Physics: Time takes you on a mind-expanding journey through the past, present, and future, guided by Professor Sean Carroll, noted author and Senior Research Associate in Physics at the California Institute of Technology.

    These 24 intriguing and enlightening lectures lay bare the inner workings of our minds – and it's all brought to you by award-winning Professor Stephen P. Hinshaw, an instructor whose training as a clinical psychologist straddles both the science of the mind and its impact on individual lives. His comprehensive and unbiased approach to this subject reveals how the science of the human mind applies to the life of our species – and to your own life as well.

    It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes.This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history – the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our children.Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and future.

    King (William and Mary University) delves into the story of how, why, where, and when we became human. These lectures will help you understand the forces that have shaped, and continue to shape, our species. "An evolutionary perspective on human behavior," notes Dr. King, "results in more than just knowledge about dates and sites when and where specific evolutionary milestones likely occurred." "It is also a window on the past and future of our species. An entirely new way of thinking comes into focus when we consider the human species within an evolutionary perspective."A Century of ScholarshipWhile covering these subjects in this 24-lecture series, Dr. King synthesizes the best that more than a century of scientific scholarship has to offer across a variety of disciplines. Biological anthropologists study primate anatomy and behavior both to understand evolution and to learn more about our common ancestor. Biological anthropologists are joined by molecular anthropologists to better understand hominids by studying fossils, ancient skeletal remains, and lifestyle information such as cave art and stone tools. Case Studies that Clarify Evolution and Its Power Dr. King begins by explaining key mechanisms through which evolution functions, citing famous and definitive case studies that demonstrate these forces. In one such landmark study, for example, biologists Peter and Rosemary Grant returned to the Galapagos Islands more than 100 years after Darwin's first voyage to conduct research on island finches. In 1977, a drought-induced scarcity of soft, edible seeds brought forth in the very next generation a population of finches with larger, stronger beaks capable of crushing larger, tougher seeds. Extraordinarily, in 1985, heavy rains produced a surplus of softer seeds, and natural selection produced a succeeding generation of the smaller-beaked variety. Evolution had occurred in two different directions within a decade. This "natural selection" is the theoretical tool of evolution, which helps us make sense of these facts. Why Evolution Remains Important to Us Today Perhaps the greatest measure of this theory's power is its relevance to our lives today. - Did you know that the gene which causes sickle cell anemia must be inherited from both parents to cause the disease but the disease does not occur when only a single gene is inherited? - Or that the single gene, in fact, affords protection from malaria? Or that race, a category so securely ingrained in our consciousness, is practically meaningless in biological terms? - Or how to evaluate the claim that a gene can be responsible for a certain personality trait? A Glimpse Into Our Selected Primate Heritage With an understanding of the basic mechanisms of evolutionary change in hand, the course looks at how our ancient primate ancestors adapted. Consider the anatomical features we share with monkeys, great apes, and other primates. Our large brains, grasping hands, and forward-facing eyes allowing us to perceive depth are critical to the way we function in the world. Yet the fossil record tells us that some 70 million years ago these distinctive primate features did not exist. What caused the first primates to emerge from existing mammalian populations? One proposed solution was that the appearance of insects living in the lower canopies of trees offered a plentiful food resource to those species adapted to procure it. Could depth perception and grasping ability have provided an advantage here, and hence been naturally selected? This is the function of biological anthropology: confronting the facts, then suggesting and testing possibilities. A Course as Much About the Present as the PastWith so much of evolutionary history taken up with the past, the insights gained in these lectures may tempt you to add questions of your own: - Is human evolution still a force in today's world? Hasn't our modern, mobile culture rendered evolution irrelevant? - In fact, human evolution is a stronger force than ever, interacting with human culture in complex ways. Issues such as obesity, AIDS, and genetics are all discussed. And you may well find these lectures opening your eyes to the extraordinary ways in which the biological power of natural selection is still at work in the world today. Course Lecture Titles1. What is Biological Anthropology? 2. How Evolution Works 3. The Debate Over Evolution 4. Matter Arising—New Species 5. Prosimians, Monkeys, and Apes 6. Monkey and Ape Social Behavior 7. The Mind of the Great Ape 8. Models for Human Ancestors? 9. Introducing the Hominids 10. Lucy and Company 11. Stones and Bones 12. Out of Africa 13. Who Were the Neandertals? 14. Did Hunting Make Us Human? 15. The Prehistory of Gender 16. Modern Human Anatomy and Behavior 17. On the Origins of Homo sapiens 18. Language 19. Do Human Races Exist? 20. Modern Human Variation 21. Body Fat, Diet, and Obesity 22. The Body and Mind Evolving 23. Tyranny of the Gene? 24. Evolution and Our Future

    Now, in The New Science of the Human Past, Reich describes just how the human genome provides not only all the information that a fertilized human egg needs to develop but also contains within it the history of our species. He delineates how the Genomic Revolution and ancient DNA are transforming our understanding of our own lineage as modern humans; how genomics deconstructs the idea that there are no biologically meaningful differences among human populations (though without adherence to pernicious racist hierarchies); and how DNA studies reveal the deep history of human inequality--among different populations, between the sexes, and among individuals within a population.

    The answer: with the essentials. Now, finally satisfy your desire for scientific inquiry in a way that makes this enormous field accessible, understandable, and undeniably captivating. Professor Viskontas boils down the scientific world into 12 key concepts every educated person should know. Devoting two lectures to each concept to give you more time to engage with it, her 24-lecture series is an engaging and enlightening introduction to everything from the behavior of subatomic particles to the latest theories about the Big Bang. Throughout, you'll get accessible looks at key building blocks of scientific knowledge, including brain plasticity, fluid mechanics, electromagnetism, genetics, quantum theory, emergence, evolution, thermodynamics, the Big Bang, and the nature of matter. Each concept is presented in a clear, concise way that will inform and delight you, and that will give you the opportunity to probe the invisible life of living cells, visit the universe seconds after its birth, and much more. Concepts that may have eluded you in school, that you may not be familiar with, or that you simply never appreciated for their intricate beauty are now brought to vivid life in a way that sticks. Welcome to the world of science - reduced to its powerful essence.

    Each part contains six audio tapes and a booklet.

    Shubin describes how over the last half-century, scientists have been able to explore how genetic recipes build bodies during embryological development--how these inventions and adaptations occur in a nonprogressive manner in different contexts, at different speeds. Paleontology has been transformed over the last 50 years by tools and techniques of molecular biology--and it is that revolution in our understanding of the evolution of life that Shubin traces here. Each of us is a mosaic of precursors that came about at different times and places, with deep rooted connections across species that Darwin, for all he understood, could never even have imagined.