Nicholas became Tsar at the age of 26. Though a conscientious man who was passionate in his devotion to his country, he was weak, sentimental, dogmatic and indecisive. Ironically he could have made an effective constitutional monarch, but these flaws rendered him fatally unsuited to be the sole ruler of a nation that was in the throes of painful modernisation. That he failed is not surprising, for many abler monarchs could not have succeeded. Rather to be wondered at is that he managed, for 23 years, to hold on to power despite the overwhelming force of circumstances. Though Nicholas was exasperating, he had many endearing qualities. A modern audience, aware - as contemporaries were not - of the private pressures under which he lived, can empathise with him and forgive some of his errors of judgement. To some readers he seems a fool, to others a monster, but many are touched by the story of a well-meaning man doing his best under impossible conditions. He is, in other words, a biographical subject that engages readers whatever their viewpoint. His family was of great importance to Nicholas. He and his wife, Alexandra, married for love and retained this affection to the end of their lives. His four daughters, all different and intriguing personalities, were beautiful and charming. His son, the family's - and the nation's - hope for the future, was disabled by an illness that had to be concealed from Russia and from the world. It was this circumstance that made possible the nefarious influence of Rasputin, which in turn hastened the end of the dynasty.This story has everything: romance and tragedy, grandeur and misery, human frailty and an international catastrophe that would not only bring down the Tsar but put an end to the glittering era of European monarchies.

    The New York Times described the book as a “hair-raising” non-fiction book that “moves with the speed of a first-rate thriller.” Publishers Weekly gave it a starred review calling it a “shocking exposé.” Follow Levine, called “America’s top undercover agent” by 60 Minutes, into the world of ruthless drug barons, kill-crazy assassins, secret police and corrupt government officials. The trail leads to the breathtakingly beautiful woman whom Pablo Escobar called "The Queen of Cocaine” – Sonia Atala. Levine, posing as Sonia’s lover, barely escapes the operation with his life but not before learning that America’s true enemies in the War on Drugs are not found in the jungles of South America but in the basements and back rooms of CIA headquarters. Operation Hun begins when Sonia Atala, deemed too powerful by the male dominated-cocaine aristocracy, is targeted for death. She strikes a secret deal: in return for protection, she will give DEA its first look into the inner workings of the organizations controlling the gusher of cocaine pouring into the US. Levine, posing as Sonia’s half-Sicilian, half-Puerto Rican Mafioso lover and business partner, is now targeted by her enemies. Supplied with a mansion, a fleet of luxury cars, an undercover Mafia crew, and a planeload of cocaine as props, he lures them to his luxurious home to settle their differences on hidden DEA video. It should have been enough evidence to indict those in control of the flow of cocaine into the US. But nothing was as it seemed. Levine discovers that Sonia has a secret: she is manipulating DEA with the help of covert and powerful forces in the US government to selectively destroy her enemies while leaving the cocaine pipeline intact. Read The Big White Lie and experience the darkest secrets of America’s War on Drugs for yourself—from one who has lived it. RECENT NEWS: During a March 3, 2011 world press conference, the President of Bolivia, Evo Morales, raised a copy The Big White Lie (La Guerra Falsa—the Spanish Translation) in front of news cameras proclaiming the book as one of the reasons he had banned DEA from his country. The photo of President Morales with the book in hand rocketed around the world. When interviewed, Levine said that if President Morales had really understood the book he would have banished CIA from his country and welcomed DEA as heroes. Now that the book is republished as an e-book, readers can decide the truth for themselves.

    " Paleo Fitness" guides you through the fitness and exercise plan anthropological evidence has proven to be the most efficient, healthiest way to live--work out in the real world, for the real world. A healthy, athletic physique is as easy as tuning in to how your body evolved. This book shows how to work out with functional, playful, and primal movements for: - improved strength, speed & stamina- greater mobility & flexibility- life-long fitness & good healthPacked with step-by-step exercises, a two-week meal plan and delicious, satisfying, healthy recipes, "Paleo Fitness" helps you use the high-intensity methods proven to increase fitness in the shortest possible time.

    It documents the scale of devastation, the likely causes and consequences, and the resilience with which people faced those pandemics.The book also provides the first comprehensive coverage of the world's greatest demographic disaster ever to descend upon a country in a short period of time - the influenza pandemic in India in 1918, which claimed more lives than all the battle casualties of World War I. And it shows the continuing relevance of learning from those times to tackle contemporary challenges, such as COVID-19.

    It is everywhere: in their new neighborhood, in their old apartment complex, and in the bodies of Ringo’s beloved family. What should a dog do when he survives a plague? Scared and confused, Ringo sets out on his journey.

    He careens off the road, smashes his vehicle and is killed instantly. But his van holds no ordinary cargo. And soon the nearby picture-postcard village of Jericho Falls will be plunged into the most terrifying disaster imaginable. A powerful lethal virus has been leaked into the peacefully innocent town. Sheriff Jack Slater and other leading citizens turn to the outside for help that the true nightmare is revealed: Jericho Falls must be wiped off the face of the earth.

    There he finds none other than Benjamin Franklin, who reveals the brilliant soldier's assignment: He is to travel to Russia disguised as a British mercenary and convince Catherine the Great not to join the British in their war with America. It is not a quest for the weak of heart, for to succeed, Selkirk must survive savage terrain, starving wolves, secret assassins, marauding Cossacks, a court of seductive young women, and even a dramatic romantic face-off with the legendary Tsarina herself.

    He was Alexander Litvinenko, Sasha to his friends, a boy from the deep Russian provinces who rose through the ranks of the world's most feared security service. Litvinenko was the man who denounced murder and corruption in the Russian government, fled from the wrath of the Kremlin, came to London and took the shilling of Moscow's avowed enemy... Now he was a martyr, condemned by foes unknown to an agonised death in a hospital bed thousands of miles from home.Martin Sixsmith draws on his long experience as the BBC's Moscow correspondent, and contact with the key London-based Russians, to dissect Alexander Litvinenko's murder. Myriad theories have been put forward since he died, but the story goes back to 2000 when hostilities were declared between the Kremlin and its political opponents. This is a war that has blown hot and cold for over six years; a war that has pitted some of Russia's strongest, richest men against the most powerful president Russia has had since Josef Stalin.The Litvinenko File is a gripping, powerful inside account of a shocking act of murder, when Russia's war with itself spilled over onto the streets of London and made the world take notice.

    Even those of us who enjoy decades of good health are touched by it eventually, either in our own lives or in those of our loved ones. And when this happens, we grapple with serious and often confusing choices about how best to live with our afflictions. "" "A Life Worth Living "is a book for people facing these difficult decisions. Robert Martensen, a physician, historian, and ethicist, draws on decades of experience with patients and friends to explore the life cycle of serious illness, from diagnosis to end of life. He connects personal stories with reflections upon mortality, human agency, and the value of "cutting-edge" technology in caring for the critically ill. Timely questions emerge: To what extent should efforts to extend human life be made? What is the value of nontraditional medical treatment? How has the American health-care system affected treatment of the critically ill? And finally, what are our doctors responsibilities to us as patients, and where do those responsibilities end? Using poignant case studies, Martensen demonstrates how we and our loved ones can maintain dignity and resilience in the face of lifes most daunting circumstances.

    Rothman's acclaimed Modern Epidemiology reflects the remarkable conceptual development of this evolving science and the engagement of epidemiologists with an increasing range of current public health concerns. This landmark work is the most comprehensive and cohesive text on the principles and methods of contemporary epidemiologic research.Coauthored by two leading epidemiologists, with 15 additional contributors, the Second Edition presents a much broader range of concepts and methods than Dr. Rothman's single-authored original edition. Coverage of basic measures and study types is more thorough and includes a new chapter on field methods. New chapters on advanced topics in data analysis, such as hierarchical regression, are also included. A new section covers specific areas of research such as infectious disease epidemiology, ecologic studies, disease surveillance, analysis of vital statistics, screening, clinical epidemiology, environmental and occupational epidemiology, reproductive and perinatal epidemiology, genetic epidemiology, and nutritional epidemiology.

    health care, patients and doctors are losing. Who Killed Health Care? shows how to win the war. One of the nation's most respected health care analysts, Regina Herzlinger exposes the motives and methods of those who have crippled America's health care system-figures in the insurance, hospital, employment, governmental, and academic sectors. She proves how our current system, which is organized around payers and providers rather than the needs of its users, is dangerously eroding patient welfare and is pushing costs out of the reach of millions.Who Killed Health Care? then outlines Herzlinger's bold new plan for a consumer-driven system that will deliver affordable, high-quality care to everyone. By putting insurance money in the hands of patients, removing the middleman in the doctor-patient relationship, and giving employers cost relief, consumers and physicians will be empowered to make the system work the way it should. Herzlinger describes in precise detail how her innovative program will provideSmaller, disease-focused medical facilities that provide complete care for patientsA national system of medical records that provides privacy with confidential access by approved practitionersMandatory performance evaluations of all hospitals and all other medical organizationsMandatory health insurance with subsidies for those who cannot afford itWho Killed Health Care? is a call to arms that must be answered; the welfare of every American hangs in the balance."A brilliant analysis... A must-read." - Bill George, Professor, Harvard Business School and Former CEO of Medtronic"As it becomes more and more obvious to everyone that our current health care system is unsustainable, this is the book that had to be written." - Daniel H. Johnson, Jr. MD, former president of the American Medical Association"Regina Herzlinger's ideas to tackle the crisis of the U.S. health care system are based on keen knowledge of the system's existing difficulties along with insights that introduce the reader to new streamlined choices that have the potential of getting both quantity and cost under control." - Joseph Kennedy, founder, chairman, and president, Citizens Energy Corporation, CEO, Citizens Health Care, former representative (D-Mass)"Regina Herzlinger... offers a vision of the way things can be, should be, and will be sooner or later. The only question is: how long do we have to wait?" - Greg Scandlen, founder, Consumers for Health Choices "Regi Herzlinger has brilliantly articulated a better way - embracing the principles of competition and innovation that cause every other sector of our economy to thrive. Discharging American health care from the ICU can only happen by putting individual Americans - not politicians and bureaucrats - back in charge of their health care decisioins." - U.S. Senator Tom Coburn (R-Okla), M.D. "Following on the heels of her landmark Market-Driven Health Care, Herzlinger lays it on the line with her expose of what many who work in the health care industry have felt in their gut. Now it is articulated in an entertaining and must-read portrayal, with you and me as the only way out." - Dennis White, executive vice president for strategic development, National Business Coalition on Health "A wonderful Orwellian romp through issues which carry a deadly irony. The killers of health care are, of course, the third parties, each of which has an itchy palm and a commitment to profit or power which exceeds the commitment to service, with each engaging the others within a politically shaped box. Rarely has the case for the public been made with so much force, foresight, and wit, and a better way forward shown so clearly." - James F. Fries, MD, Professor of Medicine, Stanford University School of Medicine "You can practically hear the war chants as Professor Herzlinger sets out her view of what's wrong with the health care system and how to fix it. You'd best read it so you can decide which side you will be on when the battle is joined." - Paul Levy, CEO, Beth Israel Hospital, Boston, MA "Regina Herzlinger, the nation's leading expert on consumer-driven health care, has given us a brilliant analysis of the flaws in our health care system and what it will take to get it back on track. Her latest book is a must-read." - Bill George, Professor of Management Practice, Harvard Business School, Former CEO, Medtronic, and author of Authentic Leadership "You don't have to agree with her diagnosis and prescription for the U.S. health care system, but you do have to read her book. Once again, Professor Herzlinger has put together a well researched, well written, and very provocative blueprint for the future of health care." Peter L. Slavin, MD, President, Massachusetts General Hospital

    Phages are also being used to detect and remove pathogens from our food supplies, both plant and animal. Also exciting is the use of phages as vehicles to delivery DNA vaccines, often directly to mammalian immune system cells. Recent work also suggests possible antitumor effects of phages. We stand on the edge of a whole new world of exploration and applications of microbiology. For over 20 years, and through five editions, Black's Microbiology: Principles and Explorations has captured students' imaginations. Her enthusiasm, passion, and knack for memorable stories and anecdotes bring the study of microbiology to life in a way few other texts can match. Now updated to reflect the latest topics in the field (e.g., SARS, bioterrorism, GMO's, geomicrobiology) and accompanied by state-of-the-art animations of key concepts, this new edition is sure to help inspire a new generation of enthusiasts for the dynamic science of microbiology. Critical Acclaim "I continue to find Black's text an excellent contribution to undergraduate Microbiology education." --Karen Messley, Rock Valley College "I like the conversational and informal style Black adopts throughout the book. This is a book, which could very well engage even the most reluctant student. It is comprehensive, nicely detailed, and incorporates many aids to teaching and learning..."--Iris Cook, Westchester CC "[The text] is a wonderful introduction into the world of microorganisms for students from a wide variety of backgrounds."--Jeff G. Leid, Northern Arizona University ..".I have found it [the book] accurate to a fault, brilliant at getting students motivated and interested in microbiology, and a great practical training book."--Gerard O'Donovan, University of North Texas Also available Laboratory Exercises in Microbiology, 2nd Edition Robert A. Pollack, et al. ISBN: 0-471-42082-4, 264 pages, paper, (c)2005 Written specifically for allied health students, this lab manual presents a variety of highly engaging activities and experiments that convey the basic concepts of microbiology.

    Spelling and grammar errors go unseen after numerous reading. But then, as Bones might say, Jim, I'm a doctor, not an editor.

    Each makes a brilliant marriage that will bring her both happiness and heartbreak. The eldest, Princess Victoria, marries the handsome Prince Louis of Battenberg, the former lover of Lillie Langtry. The next, the exquisite Elisabeth, is swept off to the unbelievable splendor of the Romanov court by Grand Duke Serge, while Irène dazzles Prince Henry of Prussia and takes her place at the court in Berlin. Alix, the youngest, marries the man she has loved since childhood, Tsar Nicholas II of Russia, and becomes the fabled Empress Alexandra.From such exotic locals as Russia, Bulgaria and Ottoman Jerusalem, to the drawing rooms of Sandringham, The Royal Mob is told as an intimate memoir of the eldest sister, Princess Victoria of Hesse, who was the favorite granddaughter of Queen Victoria. Starting in the court of the Queen Empress and ending at the marriage of Victoria’s grandson, Prince Philip, to the future Queen Elizabeth of England, The Royal Mob is the lavish and exciting story of the last royal courts of Europe.

    There is every reason to believe that, within a few weeks of its onset, the infection was universally present in the nose and throat of the people, disseminated by mouth spray given off on talking by innumerable carriers and, in addition, by the coughing and sneezing of the sick. Susceptibility was very general, though it varied greatly in degree. Among those who escaped well marked sickness there are few who could not recall having had an occluded or running nose, or a raw feeling in the throat, or a cough, or aches and pains, at some time during the period of the prevalence of the disease, these probably representing the price such persons paid for their immunization." - Dr. Bernard Fantus In many ways, it is hard for modern people living in First World countries to conceive of a pandemic sweeping around the world and killing millions of people, and it is even harder to believe that something as common as influenza could cause such widespread illness and death. Although the flu still takes hundreds of lives each year, most of those lost are very young or old or ill with something else that had already weakened them. In fact, most people contract influenza at least once, and many suffer from the flu several times in their lives and survive it with a minimum amount of medical attention. In 1918, the world was still in the throes of the Great War, the deadliest conflict in human history at that point, but while World War I would be a catastrophic war surpassed only by World War II, an unprecedented influenza outbreak that same year inflicted casualties that would make both wars pale in comparison. An illness, or more likely a collection of illnesses, Spanish influenza quickly spread across the world and may have killed upwards of 100 million people, decimating populations across developed nations and possibly wiping out as much as 5% of the world’s population. If anything, the ongoing war and the censorship maintained by the countries fighting it may have resulted in the actual toll of the outbreak being underestimated based on the way soldiers’ deaths were categorized. World War I may have distracted people about the unprecedented nature of the outbreak, but the most alarming aspect of the outbreak in 1918 was the indiscriminate nature in which the scourge attacked young and old, healthy and unhealthy, and rich and poor alike. In fact, the popular name for the outbreak was a reference to the fact that Spain’s own king was stricken with the disease. While he and President Woodrow Wilson ended up surviving it, former First Lady Rose Cleveland did not. The staggering number of fatalities, and the way in which seemingly anybody could suffer during the outbreak, taught people in the early 20th century that regardless of the tremendous strides made by technology, and no matter how stalemated the war was, nobody was safe from nature itself. Of course, it also demonstrated how much more work could be done to prevent similar occurrences. The 1918 pandemic was neither the first nor the last outbreak of the flu, but it was by far the worst, and it forever changed the face of medicine and public health care in both North America and Europe. The 1918 Spanish Flu Pandemic: The History and Legacy of the World’s Deadliest Outbreak chronicles the devastating disease and the damage it wrought across the globe.