The latest edition offers greatly expanded coverage of directed mutagenesis and protein engineering, therapeutic agents, and genetic engineering of plants. Updated chapters reflect recent developments in biotechnology and the societal issues related to it, such as cloning, gene therapy, and patenting and releasing genetically engineered organisms. Over 480 figures, including 200 that are new in this edition, illustrate all key concepts. "Milestones" summarize important research papers in the history of biotechnology and their effects on the field. As in previous editions, the authors clearly explain all concepts and techniques to provide maximum understanding of the subject, avoiding confusing scientific jargon and excessive detail wherever possible. Each chapter concludes with a summary, references, and review questions. Ideally suited as a text for third- and fourth-year undergraduates as well as graduate students, this book is also an excellent reference for health professionals, scientists, engineers, or attorneys interested in biotechnology.

     During fourteen years, from 1955 to 1969, the Soviet Union and the United States of America were engaged in a dramatic race against each other to conquer space. This period encompassed dramatic victories, humbling defeats, and more than one tragedy. This is a story of human courage and ingenuity at its best and political maneuvering at its worst, of almost unbelievable technological progress undertaken with the object not just of advancing human knowledge but also of proving the superiority of one country over another. Inside you will read about... ✓ From Missiles to Rockets ✓ Russia Takes the Lead ✓ Early American Failures ✓ The First Men in Space ✓ Fatalities on Both Sides ✓ The Moon Landing And much more! The space race culminated in man setting foot upon the moon, but each milestone on the way to that final goal was bitterly contested. Two powerful nations pledged a substantial part of their national resources to beat the other in a scientific and technological race to be the first to achieve new records. In terms of contests between major powers, there has never been anything quite as dramatic, public, and sustained as the space race; it remains one of the most fascinating and engaging episodes of the Cold War.

    But which one? And how?Over the past fifty years, more than three hundred infectious diseases have either newly emerged or reemerged, appearing in territories where they’ve never been seen before. Ninety percent of epidemiologists expect that one of them will cause a deadly pandemic sometime in the next two generations. It could be Ebola, avian flu, a drug-resistant superbug, or something completely new. While we can’t know which pathogen will cause the next pandemic, by unraveling the story of how pathogens have caused pandemics in the past, we can make predictions about the future. In Pandemic: Tracking Contagions, from Cholera to Ebola and Beyond, the prizewinning journalist Sonia Shah—whose book on malaria, The Fever, was called a “tour-de-force history” (The New York Times) and “revelatory” (The New Republic)—interweaves history, original reportage, and personal narrative to explore the origins of contagions, drawing parallels between cholera, one of history’s most deadly and disruptive pandemic-causing pathogens, and the new diseases that stalk humankind today.To reveal how a new pandemic might develop, Sonia Shah tracks each stage of cholera’s dramatic journey, from its emergence in the South Asian hinterlands as a harmless microbe to its rapid dispersal across the nineteenth-century world, all the way to its latest beachhead in Haiti. Along the way she reports on the pathogens now following in cholera’s footsteps, from the MRSA bacterium that besieges her own family to the never-before-seen killers coming out of China’s wet markets, the surgical wards of New Delhi, and the suburban backyards of the East Coast.By delving into the convoluted science, strange politics, and checkered history of one of the world’s deadliest diseases, Pandemic reveals what the next global contagion might look like— and what we can do to prevent it.

    From humorous fishing excursions and frightening bear encounters to snow blinding blizzards and quirky characters, they come face to face with the unpredictable Mother Nature and learn the value of friendship, survival, and solitude in a picturesque but harsh life by the sea. Packed with adventures, challenges, and true Alaskan lifestyle.

    Hailed as "unsinkable, " the "Kursk" was on maneuvers when mysterious explosions rocked the sub, causing it to sink to the bottom of the sea with its 118-man crew. This in-depth look at the disaster reveals previously unreleased information from family members of the deceased as well as from government officials.

    

    The DOs chronicles the development of this controversial medical movement from the nineteenth century to the present. Historian Norman Gevitz describes the philosophy and practice of osteopathy, as well as its impact on medical care. From the theories underlying the use of spinal manipulation developed by osteopathy's founder, Andrew Taylor Still, Gevitz traces the movement's early success, despite attacks from the orthodox medical community, and details the internal struggles to broaden osteopathy's scope to include the full range of pharmaceuticals and surgery. He also recounts the efforts of osteopathic colleges to achieve parity with institutions granting M.D. degrees and looks at the continuing effort by osteopathic physicians and surgeons to achieve greater recognition and visibility.In print continuously since 1982, The DOs has now been thoroughly updated and expanded to include two new chapters addressing recent and current challenges and to bring the history of the profession up to the beginning of the new millennium.

    Even though we all have heard that the odds of being struck by lightning are greater than the odds of perishing in a plane crash, it still doesn't feel that way. Airplane crashes might be rare, but they do happen, and they’re usually fatal. David Soucie insists that most of these deaths could be prevented.He’s worked as a pilot, a mechanic, an FAA inspector, and an aviation executive. He’s seen death up close and personal—deaths of colleagues and friends that might have been pre-vented if he had approved certain safety measures in the aircrafts they were handling. His years of experience have led Dave to become an impassioned consultant on the topic of air-line safety. This includes not only advising the Obama administration, but also taking a leading role in the congressionally funded NextGen interdepartmental initiative in regards to both the department of transportation and the departments of defense, homeland security, FBI, CIA, and others. Find out the truth about airplane safety and discover what the future holds for air travel.

    

    The world of golf is at a crossroads. As tech­nological innovations displace traditional philosophies, the golfing community has splintered into two deeply combative factions: the old-school teachers and players who believe in feel, artistry, and imagination, and the technical minded who want to remake the game around data. In Golf’s Holy War, Brett Cyrgalis takes readers inside the heated battle playing out from weekend hackers to PGA Tour pros. At the Titleist Performance Institute in Oceanside, California, golfers clad in full-body sensors target weaknesses in their biomechanics, while others take part in mental exercises designed to test their brain’s psychological resilience. Meanwhile, coaches like Michael Hebron purge golfers of all technical infor­mation, tapping into the power of intuitive physical learning by playing rudimentary games. From historic St. Andrews to manicured Augusta, experimental com­munes in California to corporatized conferences in Orlando, William James to Ben Hogan to theoretical physics, the factions of the spiritual and technical push to redefine the boundaries of the game. And yet what does it say that Tiger Woods has orchestrated one of the greatest comebacks in sports history without the aid of a formal coach? But Golf’s Holy War is more than just a book about golf—it’s a story about modern life and how we are torn between resisting and embracing the changes brought about by the advancements of science and technology. It’s also an exploration of historical legacies, the enriching bonds of education, and the many interpretations of reality.

    And as outbreaks of COVID-19, Ebola, MERS, and Zika have demonstrated, we are woefully underprepared to deal with the fallout. So what can -- and must -- we do in order to protect ourselves from mankind's deadliest enemy?Drawing on the latest medical science, case studies, policy research, and hard-earned epidemiological lessons, Deadliest Enemy explores the resources and programs we need to develop if we are to keep ourselves safe from infectious disease. The authors show how we could wake up to a reality in which many antibiotics no longer cure, bioterror is a certainty, and the threat of a disastrous influenza or coronavirus pandemic looms ever larger. Only by understanding the challenges we face can we prevent the unthinkable from becoming the inevitable.Deadliest Enemy is high scientific drama, a chronicle of medical mystery and discovery, a reality check, and a practical plan of action.

    She documents her early days in the Democratic Party and the Democratic Alliance, at a time when the party was locked in a no-holds-barred factional conflict. And she chronicles the intense political battles to become mayor of Cape Town, leader of the DA and premier of the Western Cape, in the face of dirty tricks from the ANC and infighting within her own party.This is a story about political intrigue and treachery, floor-crossing and unlikely coalitions, phone tapping and intimidation, false criminal charges and judicial commissions. It documents Zille’s courageous fight against corruption and state capture and her efforts to realign politics and entrench accountability. And it describes a mother’s battle to raise children in the pressured world of South African politics.This book is as frank, honest and unflinching as Helen Zille herself, and will appeal to anyone interested in the story of South African politics over the past fifty years.

    On board were thirty barely clad black men, armed with cutlasses, and two white men - Spanish slave owners with an incredible story to tell. A month earlier, the Amistad had set sail from Havana with a valuable cargo of slaves and $40,000 worth of gold doubloons. She was headed for the Cuban coastal town of Puerto Principe - but in a matter of days, the captain and the cook were dead, and the ship was in the control of the slaves. Thus began "the Amistad affair," which, writes Mary Cable, "was to bedevil the diplomatic relations of the United States, Spain, and England for a generation; intensify bitterness over the question of slavery; and lead an ex-president (John Quincy Adams) to go before the Supreme Court and castigate the administration in an eloquent plea for the slaves' freedom. In her fascinating and carefully researched account, Cable takes us right to the heart of these complex matters, dramatically replaying an incredible series of events that converged to form a uniquely exciting and challenging chapter in American history.

    An exploration of technology used by ancient civilizations and the support it provides for certain biblical interpretations.

    Every person alive today is descended from him. How did this real-life Adam wind up as the father of us all? What happened to the descendants of other men who lived at the same time? And why, if modern humans share a single prehistoric ancestor, do we come in so many sizes, shapes, and races?Examining the hidden secrets of human evolution in our genetic code, Spencer Wells reveals how developments in the revolutionary science of population genetics have made it possible to create a family tree for the whole of humanity. Replete with marvelous anecdotes and remarkable information, from the truth about the real Adam and Eve to the way differing racial types emerged, The Journey of Man is an enthralling, epic tour through the history and development of early humankind.