A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution


Jennifer A. Doudna - 2017
    Two scientists explore the potential of a revolutionary genetics technology capable of easily and affordably manipulating DNA in human embryos to prevent specific diseases, addressing key concerns about related ethical and societal repercussions.

The Laws of Thermodynamics: A Very Short Introduction


Peter Atkins - 1990
    From the sudden expansion of a cloud of gas to the cooling of hot metal--everything is moved or restrained by four simple laws. Written by Peter Atkins, one of the world's leading authorities on thermodynamics, this powerful and compact introduction explains what these four laws are and how they work, using accessible language and virtually no mathematics. Guiding the reader a step at a time, Atkins begins with Zeroth (so named because the first two laws were well established before scientists realized that a third law, relating to temperature, should precede them--hence the jocular name zeroth), and proceeds through the First, Second, and Third Laws, offering a clear account of concepts such as the availability of work and the conservation of energy. Atkins ranges from the fascinating theory of entropy (revealing how its unstoppable rise constitutes the engine of the universe), through the concept of free energy, and to the brink, and then beyond the brink, of absolute zero. About the Series: Combining authority with wit, accessibility, and style, Very Short Introductions offer an introduction to some of life's most interesting topics. Written by experts for the newcomer, they demonstrate the finest contemporary thinking about the central problems and issues in hundreds of key topics, from philosophy to Freud, quantum theory to Islam.

Quantum Computing Since Democritus


Scott Aaronson - 2013
    Full of insights, arguments and philosophical perspectives, the book covers an amazing array of topics. Beginning in antiquity with Democritus, it progresses through logic and set theory, computability and complexity theory, quantum computing, cryptography, the information content of quantum states and the interpretation of quantum mechanics. There are also extended discussions about time travel, Newcomb's Paradox, the anthropic principle and the views of Roger Penrose. Aaronson's informal style makes this fascinating book accessible to readers with scientific backgrounds, as well as students and researchers working in physics, computer science, mathematics and philosophy.

The Data Detective: Ten Easy Rules to Make Sense of Statistics


Tim Harford - 2020
    That’s a mistake, Tim Harford says in The Data Detective. We shouldn’t be suspicious of statistics—we need to understand what they mean and how they can improve our lives: they are, at heart, human behavior seen through the prism of numbers and are often “the only way of grasping much of what is going on around us.” If we can toss aside our fears and learn to approach them clearly—understanding how our own preconceptions lead us astray—statistics can point to ways we can live better and work smarter.As “perhaps the best popular economics writer in the world” (New Statesman), Tim Harford is an expert at taking complicated ideas and untangling them for millions of readers. In The Data Detective, he uses new research in science and psychology to set out ten strategies for using statistics to erase our biases and replace them with new ideas that use virtues like patience, curiosity, and good sense to better understand ourselves and the world. As a result, The Data Detective is a big-idea book about statistics and human behavior that is fresh, unexpected, and insightful.

Structures: Or Why Things Don't Fall Down


J.E. Gordon - 1978
    Gordon strips engineering of its confusing technical terms, communicating its founding principles in accessible, witty prose.For anyone who has ever wondered why suspension bridges don't collapse under eight lanes of traffic, how dams hold back--or give way under--thousands of gallons of water, or what principles guide the design of a skyscraper, a bias-cut dress, or a kangaroo, this book will ease your anxiety and answer your questions.Structures: Or Why Things Don't Fall Down is an informal explanation of the basic forces that hold together the ordinary and essential things of this world--from buildings and bodies to flying aircraft and eggshells. In a style that combines wit, a masterful command of his subject, and an encyclopedic range of reference, Gordon includes such chapters as "How to Design a Worm" and "The Advantage of Being a Beam," offering humorous insights in human and natural creation.Architects and engineers will appreciate the clear and cogent explanations of the concepts of stress, shear, torsion, fracture, and compression. If you're building a house, a sailboat, or a catapult, here is a handy tool for understanding the mechanics of joinery, floors, ceilings, hulls, masts--or flying buttresses.Without jargon or oversimplification, Structures opens up the marvels of technology to anyone interested in the foundations of our everyday lives.

The Signal and the Noise: Why So Many Predictions Fail—But Some Don't


Nate Silver - 2012
    He solidified his standing as the nation's foremost political forecaster with his near perfect prediction of the 2012 election. Silver is the founder and editor in chief of FiveThirtyEight.com. Drawing on his own groundbreaking work, Silver examines the world of prediction, investigating how we can distinguish a true signal from a universe of noisy data. Most predictions fail, often at great cost to society, because most of us have a poor understanding of probability and uncertainty. Both experts and laypeople mistake more confident predictions for more accurate ones. But overconfidence is often the reason for failure. If our appreciation of uncertainty improves, our predictions can get better too. This is the "prediction paradox": The more humility we have about our ability to make predictions, the more successful we can be in planning for the future.In keeping with his own aim to seek truth from data, Silver visits the most successful forecasters in a range of areas, from hurricanes to baseball, from the poker table to the stock market, from Capitol Hill to the NBA. He explains and evaluates how these forecasters think and what bonds they share. What lies behind their success? Are they good-or just lucky? What patterns have they unraveled? And are their forecasts really right? He explores unanticipated commonalities and exposes unexpected juxtapositions. And sometimes, it is not so much how good a prediction is in an absolute sense that matters but how good it is relative to the competition. In other cases, prediction is still a very rudimentary-and dangerous-science.Silver observes that the most accurate forecasters tend to have a superior command of probability, and they tend to be both humble and hardworking. They distinguish the predictable from the unpredictable, and they notice a thousand little details that lead them closer to the truth. Because of their appreciation of probability, they can distinguish the signal from the noise.

The Origin of Species


Charles Darwin - 1859
    Yet The Origin of Species (1859) is also a humane and inspirational vision of ecological interrelatedness, revealing the complex mutual interdependencies between animal and plant life, climate and physical environment, and—by implication—within the human world. Written for the general reader, in a style which combines the rigour of science with the subtlety of literature, The Origin of Species remains one of the founding documents of the modern age.

Paradox: The Nine Greatest Enigmas in Physics


Jim Al-Khalili - 2012
    A fun and fascinating look at great scientific paradoxes.   Throughout history, scientists have come up with theories and ideas that just don't seem to make sense.  These we call paradoxes.  The paradoxes Al-Khalili offers are drawn chiefly from physics and astronomy and represent those that have stumped some of the finest minds.  For example, how can a cat be both dead and alive at the same time?  Why will Achilles never beat a tortoise in a race, no matter how fast he runs?  And how can a person be ten years older than his twin?   With elegant explanations that bring the reader inside the mind of those who've developed them, Al-Khalili helps us to see that, in fact, paradoxes can be solved if seen from the right angle.  Just as surely as Al-Khalili narrates the enduring fascination of these classic paradoxes, he reveals their underlying logic.  In doing so, he brings to life a select group of the most exciting concepts in human knowledge.  Paradox is mind-expanding fun.

How to Teach Quantum Physics to Your Dog


Chad Orzel - 2009
    Could she use quantum tunnelling to get through the neighbour's fence and chase bunnies? What about quantum teleportation to catch squirrels before they climb out of reach? In this witty and informative book, Orzel and Emmy - the talking dog - discuss the key theories of Quantum Physics and its fascinating history. From quarks and gluons to Heisenberg's uncertainty principle, this is the perfect introduction to the fundamental laws which govern the universe.

The Clockwork Universe: Isaac Newton, the Royal Society, and the Birth of the Modern World


Edward Dolnick - 2011
    A meld of history and science, this book is a group portrait of some of the greatest minds who ever lived as they wrestled with nature’s most sweeping mysteries. The answers they uncovered still hold the key to how we understand the world.At the end of the seventeenth century—an age of religious wars, plague, and the Great Fire of London—when most people saw the world as falling apart, these earliest scientists saw a world of perfect order. They declared that, chaotic as it looked, the universe was in fact as intricate and perfectly regulated as a clock. This was the tail end of Shakespeare’s century, when the natural land the supernatural still twined around each other. Disease was a punishment ordained by God, astronomy had not yet broken free from astrology, and the sky was filled with omens. It was a time when little was known and everything was new. These brilliant, ambitious, curious men believed in angels, alchemy, and the devil, and they also believed that the universe followed precise, mathematical laws—-a contradiction that tormented them and changed the course of history.The Clockwork Universe is the fascinating and compelling story of the bewildered geniuses of the Royal Society, the men who made the modern world.

A New Kind of Science


Stephen Wolfram - 1997
    Wolfram lets the world see his work in A New Kind of Science, a gorgeous, 1,280-page tome more than a decade in the making. With patience, insight, and self-confidence to spare, Wolfram outlines a fundamental new way of modeling complex systems. On the frontier of complexity science since he was a boy, Wolfram is a champion of cellular automata--256 "programs" governed by simple nonmathematical rules. He points out that even the most complex equations fail to accurately model biological systems, but the simplest cellular automata can produce results straight out of nature--tree branches, stream eddies, and leopard spots, for instance. The graphics in A New Kind of Science show striking resemblance to the patterns we see in nature every day. Wolfram wrote the book in a distinct style meant to make it easy to read, even for nontechies; a basic familiarity with logic is helpful but not essential. Readers will find themselves swept away by the elegant simplicity of Wolfram's ideas and the accidental artistry of the cellular automaton models. Whether or not Wolfram's revolution ultimately gives us the keys to the universe, his new science is absolutely awe-inspiring. --Therese Littleton

Are We Smart Enough to Know How Smart Animals Are?


Frans de Waal - 2016
    But in recent decades, these claims have eroded, or even been disproven outright, by a revolution in the study of animal cognition. Take the way octopuses use coconut shells as tools; elephants that classify humans by age, gender, and language; or Ayumu, the young male chimpanzee at Kyoto University whose flash memory puts that of humans to shame. Based on research involving crows, dolphins, parrots, sheep, wasps, bats, whales, and of course chimpanzees and bonobos, Frans de Waal explores both the scope and the depth of animal intelligence. He offers a firsthand account of how science has stood traditional behaviorism on its head by revealing how smart animals really are, and how we’ve underestimated their abilities for too long.People often assume a cognitive ladder, from lower to higher forms, with our own intelligence at the top. But what if it is more like a bush, with cognition taking different forms that are often incomparable to ours? Would you presume yourself dumber than a squirrel because you’re less adept at recalling the locations of hundreds of buried acorns? Or would you judge your perception of your surroundings as more sophisticated than that of a echolocating bat? De Waal reviews the rise and fall of the mechanistic view of animals and opens our minds to the idea that animal minds are far more intricate and complex than we have assumed. De Waal’s landmark work will convince you to rethink everything you thought you knew about animal—and human—intelligence.

Naked Statistics: Stripping the Dread from the Data


Charles Wheelan - 2012
    How can we catch schools that cheat on standardized tests? How does Netflix know which movies you’ll like? What is causing the rising incidence of autism? As best-selling author Charles Wheelan shows us in Naked Statistics, the right data and a few well-chosen statistical tools can help us answer these questions and more.For those who slept through Stats 101, this book is a lifesaver. Wheelan strips away the arcane and technical details and focuses on the underlying intuition that drives statistical analysis. He clarifies key concepts such as inference, correlation, and regression analysis, reveals how biased or careless parties can manipulate or misrepresent data, and shows us how brilliant and creative researchers are exploiting the valuable data from natural experiments to tackle thorny questions.And in Wheelan’s trademark style, there’s not a dull page in sight. You’ll encounter clever Schlitz Beer marketers leveraging basic probability, an International Sausage Festival illuminating the tenets of the central limit theorem, and a head-scratching choice from the famous game show Let’s Make a Deal—and you’ll come away with insights each time. With the wit, accessibility, and sheer fun that turned Naked Economics into a bestseller, Wheelan defies the odds yet again by bringing another essential, formerly unglamorous discipline to life.

Weapons of Math Destruction: How Big Data Increases Inequality and Threatens Democracy


Cathy O'Neil - 2016
    Increasingly, the decisions that affect our lives--where we go to school, whether we can get a job or a loan, how much we pay for health insurance--are being made not by humans, but by machines. In theory, this should lead to greater fairness: Everyone is judged according to the same rules.But as mathematician and data scientist Cathy O'Neil reveals, the mathematical models being used today are unregulated and uncontestable, even when they're wrong. Most troubling, they reinforce discrimination--propping up the lucky, punishing the downtrodden, and undermining our democracy in the process.

What Is Life? with Mind and Matter and Autobiographical Sketches


Erwin Schrödinger - 1944
    The book was based on a course of public lectures delivered by Schrödinger in February 1943 at Trinity College, Dublin. Schrödinger's lecture focused on one important question: "how can the events in space and time which take place within the spatial boundary of a living organism be accounted for by physics and chemistry?" In the book, Schrödinger introduced the idea of an "aperiodic crystal" that contained genetic information in its configuration of covalent chemical bonds. In the 1950s, this idea stimulated enthusiasm for discovering the genetic molecule and would give both Francis Crick and James Watson initial inspiration in their research.