Where are we? Who are we? Are our emotions, our beliefs, and our hopes and dreams ultimately meaningless out there in the void? Does human purpose and meaning fit into a scientific worldview?In short chapters filled with intriguing historical anecdotes, personal asides, and rigorous exposition, readers learn the difference between how the world works at the quantum level, the cosmic level, and the human level--and then how each connects to the other.  Carroll's presentation of the principles that have guided the scientific revolution from Darwin and Einstein to the origins of life, consciousness, and the universe is dazzlingly unique.Carroll shows how an avalanche of discoveries in the past few hundred years has changed our world and what really matters to us. Our lives are dwarfed like never before by the immensity of space and time, but they are redeemed by our capacity to comprehend it and give it meaning.The Big Picture is an unprecedented scientific worldview, a tour de force that will sit on shelves alongside the works of Stephen Hawking, Carl Sagan, Daniel Dennett, and E. O. Wilson for years to come.

    Dennett, whom Chet Raymo of The Boston Globe calls "one of the most provocative thinkers on the planet," focuses his unerringly logical mind on the theory of natural selection, showing how Darwin's great idea transforms and illuminates our traditional view of humanity's place in the universe. Dennett vividly describes the theory itself and then extends Darwin's vision with impeccable arguments to their often surprising conclusions, challenging the views of some of the most famous scientists of our day.

    Most conservationists and environmentalists share this view. But what if the traditional view of ecology is wrong—what if true environmentalists should be applauding the invaders? In The New Wild, Pearce goes on a journey across six continents to rediscover what conservation in the twenty-first century should be about. Pearce explores ecosystems from remote Pacific islands to the United Kingdom, from San Francisco Bay to the Great Lakes, as he digs into questionable estimates of the cost of invader species and reveals the outdated intellectual sources of our ideas about the balance of nature. Pearce acknowledges that there are horror stories about alien species disrupting ecosystems, but most of the time, the tens of thousands of introduced species usually swiftly die out or settle down and become model eco-citizens. The case for keeping out alien species, he finds, looks increasingly flawed. As Pearce argues, mainstream environmentalists are right that we need a rewilding of the earth, but they are wrong if they imagine that we can achieve that by reengineering ecosystems. Humans have changed the planet too much, and nature never goes backward. But a growing group of scientists is taking a fresh look at how species interact in the wild. According to these new ecologists, we should applaud the dynamism of alien species and the novel ecosystems they create. In an era of climate change and widespread ecological damage, it is absolutely crucial that we find ways to help nature regenerate. Embracing the new ecology, Pearce shows us, is our best chance. To be an environmentalist in the twenty-first century means celebrating nature’s wildness and capacity for change.

    But soon, Earth's isolation could come to an end. Over the past two decades, astronomers have discovered thousands of planets orbiting other stars. Some of these exoplanets may be mirror images of our own world. And more are being found all the time.Yet as the pace of discovery quickens, an answer to the universe's greatest riddle still remains just out of reach: Is the great silence and emptiness of the cosmos a sign that we and our world are somehow singular, special, and profoundly alone, or does it just mean that we’re looking for life in all the wrong places? As star-gazing scientists come closer to learning the truth, their insights are proving ever more crucial to understanding life’s intricate mysteries and possibilities right here on Earth.Science journalist Lee Billings explores the past and future of the "exoplanet boom" through in-depth reporting and interviews with the astronomers andplanetary scientists at its forefront. He recounts the stories behind their world-changing discoveries and captures the pivotal moments that drove them forward in their historic search for the first habitable planets beyond our solar system. Billings brings readers close to a wide range of fascinating characters, such as:FRANK DRAKE, a pioneer who has used the world’s greatest radio telescopes to conduct the first searches for extraterrestrial intelligence and to transmit a message to the stars so powerful that it briefly outshone our Sun.JIM KASTING, a mild-mannered former NASA scientist whose research into the Earth’s atmosphere and climate reveals the deepest foundations of life on our planet, foretells the end of life on Earth in the distant future, and guides the planet hunters in their search for alien life.SARA SEAGER, a visionary and iron-willed MIT professor who dreams of escaping the solar system and building the giant space telescopes required to discover and study life-bearing planets around hundreds of the Sun’s neighboring stars.Through these and other captivating tales, Billings traces the triumphs, tragedies, and betrayals of the extraordinary men and women seeking life among the stars. In spite of insufficient funding, clashing opinions, and the failings of some of our world’s most prominent and powerful scientific organizations, these planet hunters will not rest until they find the meaning of life in the infinite depths of space. Billings emphasizes that the heroic quest for other Earth-like planets is not only a scientific pursuit, but also a reflection of our own culture’s timeless hopes and fears.

    In Under the Knife, surgeon Arnold Van de Laar uses his own experience and expertise to tell the witty history of the past, present and future of surgery.From the story of the desperate man from seventeenth-century Amsterdam who grimly cut a stone out of his own bladder to Bob Marley's deadly toe, Under the Knife offers all kinds of fascinating and unforgettable insights into medicine and history via the operating theatre.What happens during an operation? How does the human body respond to being attacked by a knife, a bacterium, a cancer cell or a bullet? And, as medical advances continuously push the boundaries of what medicine can cure, what are the limits of surgery?From the dark centuries of bloodletting and of amputations without anaesthetic to today's sterile, high-tech operating theatres, Under the Knife is both a rich cultural history, and a modern anatomy class for us all.

    In that spirit, Edge.org publisher and author of Know This, John Brockman, asks 206 of the world’s most brilliant minds the 2017 Edge Question: What scientific term or concept ought to be more widely known?Contributors include: author of The God Delusion RICHARD DAWKINS on using animals’ “Genetic Book of the Dead” to reconstruct ecological history; MacArthur Fellow REBECCA NEWBERGER GOLDSTEIN on “scientific realism,” the idea that scientific theories explain phenomena beyond what we can see and touch; author of Seven Brief Lessons on Physics CARLO ROVELLI on “relative information,” which governs the physical world around us; theoretical physicist LAWRENCE M. KRAUSS on the hidden blessings of “uncertainty”; cognitive scientist and author of The Language Instinct STEVEN PINKER on “The Second Law of Thermodynamics”; biogerontologist AUBREY DE GREY on why “maladaptive traits” have been conserved evolutionarily; musician BRIAN ENO on “confirmation bias” in the internet age; Man Booker-winning author of Atonement IAN MCEWAN on the “Navier-Stokes Equations,” which govern everything from weather prediction to aircraft design and blood flow; plus pieces from RICHARD THALER, JARED DIAMOND, NICHOLAS CARR, JANNA LEVIN, LISA RANDALL, KEVIN KELLY, DANIEL COLEMAN, FRANK WILCZEK, RORY SUTHERLAND, NINA JABLONSKI, MARTIN REES, ALISON GOPNIK, and many, many others.

    Hazen writes of how the co-evolution of the geosphere and biosphere—of rocks and living matter—has shaped our planet into the only one of its kind in the Solar System, if not the entire cosmos.With an astrobiologist’s imagination, a historian’s perspective, and a naturalist’s passion for the ground beneath our feet, Hazen explains how changes on an atomic level translate into dramatic shifts in Earth’s makeup over its 4.567 billion year existence. He calls upon a flurry of recent discoveries to portray our planet’s many iterations in vivid detail. Through his theory of “co-evolution,” we learn how reactions between organic molecules and rock crystals may have generated Earth’s first organisms, which in turn are responsible for more than two-thirds of the mineral varieties on the planet.The Story of Earth is also the story of the pioneering men and women behind the sciences. Readers will meet black-market meteorite hawkers of the Sahara Desert, the gun-toting Feds who guarded the Apollo missions’ lunar dust, and the World War II Navy officer whose super-pressurized “bomb”—recycled from military hardware—first simulated the molten rock of Earth’s mantle. As a mentor to a new generation of scientists, Hazen introduces the intrepid young explorers whose dispatches from Earth’s harshest landscapes will revolutionize geology.

    Dr. Jeremy Brown, currently Director of Emergency Care Research at the National Institutes of Health, expounds on the flu's deadly past to solve the mysteries that could protect us from the next outbreak. In Influenza, he talks with leading epidemiologists, policy makers, and the researcher who first sequenced the genetic building blocks of the original 1918 virus to offer both a comprehensive history and a roadmap for understanding what’s to come.Dr. Brown digs into the discovery and resurrection of the flu virus in the frozen victims of the 1918 epidemic, as well as the bizarre remedies that once treated the disease, such as whiskey and blood-letting. Influenza also breaks down the current dialogue surrounding the disease, explaining the controversy over vaccinations, antiviral drugs like Tamiflu, and the federal government’s role in preparing for pandemic outbreaks. Though 100 years of advancement in medical research and technology have passed since the 1918 disaster, Dr. Brown warns that many of the most vital questions about the flu virus continue to confound even the leading experts.Influenza is an enlightening and unnerving look at a shapeshifting deadly virus that has been around long before people—and warns us that it may be many more years before we are able to conquer it for good.

    They always keep a bag packed. They seldom have more than twenty-four hours' notice before they are dispatched. The phone calls that tell them to head to the airport, sometimes in the middle of the night, may give them no more information than the country they are traveling to and the epidemic they will tackle when they get there.The universal human instinct is to run from an outbreak of disease. These doctors run toward it.They are the disease detective corps of the U.S. Centers for Disease Control and Prevention (CDC), the federal agency that tracks and tries to prevent disease outbreaks and bioterrorist attacks around the world. They are formally called the Epidemic Intelligence Service (EIS) -- a group founded more than fifty years ago out of fear that the Korean War might bring the use of biological weapons -- and, like intelligence operatives in the traditional sense, they perform their work largely in anonymity. They are not household names, but over the years they were first to confront the outbreaks that became known as hantavirus, Ebola virus, and AIDS. Now they hunt down the deadly threats that dominate our headlines: West Nile virus, anthrax, and SARS.In this riveting narrative, Maryn McKenna -- the only journalist ever given full access to the EIS in its fifty-three-year history -- follows the first class of disease detectives to come to the CDC after September 11, the first to confront not just naturally occurring outbreaks but the man-made threat of bioterrorism. They are talented researchers -- many with young families -- who trade two years of low pay and extremely long hours for the chance to be part of the group that has helped eradicate smallpox, push back polio, and solve the first major outbreaks of Legionnaires' disease, toxic shock syndrome, and "E. coli" O157.Urgent, exhilarating, and compelling, "Beating Back the Devil" goes with the EIS as they try to stop epidemics -- before the epidemics stop us.

    Improper use of antibiotics. Local warfare. Massive refugee migration. Changing social and environmental conditions around the world have fostered the spread of new and potentially devastating viruses and diseases—HIV, Lassa, Ebola, and others. Laurie Garrett takes you on a fifty-year journey through the world's battles with microbes and examines the worldwide conditions that have culminated in recurrent outbreaks of newly discovered diseases, epidemics of diseases migrating to new areas, and mutated old diseases that are no longer curable. She argues that it is not too late to take action to prevent the further onslaught of viruses and microbes, and offers possible solutions for a healthier future.

    Jen Gunter, the internet’s most fearless advocate for women’s health, brings you empowerment through knowledge by countering stubborn myths and misunderstandings about menopause with hard facts, real science, fascinating historical perspective, and expert advice.The only thing predictable about menopause is its unpredictability. Factor in widespread misinformation, a lack of research, and the culture of shame around women's bodies, and it's no wonder women are unsure what to expect during the menopause transition and beyond.Menopause is not a disease--it's a planned change, like puberty. And just like puberty, we should be educated on what's to come years in advance, rather than the current practice of leaving people on their own with bothersome symptoms and too much conflicting information. Knowing what is happening, why, and what to do about it is both empowering and reassuring.Frank and funny, Dr. Jen debunks misogynistic attitudes and challenges theover-mystification of menopause to reveal everything you really need to know about:- Perimenopause - Hot flashes - Sleep disruption - Sex and libido - Depression and mood changes - Skin and hair issues - Outdated therapies - Breast health - Weight and muscle mass - Health maintenance screening - And much more!Filled with practical, reassuring information, this essential guide will revolutionize how women experience menopause--including how their lives can be even better for it!

    It explains all this and much more. It discloses the best time to have a sex change, how to have a virgin birth, when to seduce your sisters or eat your lover. Quirky and brilliant, it takes as its starting point all creatures great and small worried about their bizarre sex lives, and the letters they write to the wise Dr Tatiana, the only agony aunt in all creation with a prodigious knowledge of both natural history and evolutionary biology.

    Here is the sweeping story of a substance that has been feared, revered, mythologized, and used in magic and medicine from earliest times--a substance that has become the center of a huge, secretive, and often dangerous worldwide commerce.Winner of the Los Angeles Times Book Prize, Blood was described by judges as "a gripping page-turner, a significant contribution to the history of medicine and technology and a cautionary tale. Meticulously reported and exhaustively documented."

    In Counting Backwards, pediatric anesthesiologist Dr. Henry Jay Przybylo delivers an unforgettable account of the procedure’s daily dramas and fundamental mysteries. Przybylo has administered anesthesia more than 30,000 times over his thirty-year career: on newborn babies, screaming toddlers, sullen teenagers, even a gorilla. Filled with intense moments of near-disaster, life-saving successes, and simple grace, Counting Backwards is for anyone curious about what happens after we lose consciousness.

    Until Mary's incredible discovery, it was widely believed that animals did not become extinct. The child of a poor family, Mary became a fossil hunter, inspiring the tongue-twister, "She Sells Sea Shells by the Seashore." She attracted the attention of fossil collectors and eventually the scientific world. Once news of the fossils reached the halls of academia, it became impossible to ignore the truth. Mary's peculiar finds helped lay the groundwork for Charles Darwin's theory of evolution, laid out in his On the Origin of Species. Darwin drew on Mary's fossilized creatures as irrefutable evidence that life in the past was nothing like life in the present.A story worthy of Dickens, The Fossil Hunter chronicles the life of this young girl, with dirt under her fingernails and not a shilling to buy dinner, who became a world-renowned paleontologist. Dickens himself said of Mary: "The carpenter's daughter has won a name for herself, and deserved to win it."Here at last, Shelley Emling returns Mary Anning, of whom Stephen J. Gould remarked, is "probably the most important unsung (or inadequately sung) collecting force in the history of paleontology," to her deserved place in history.