Each chapter focuses on one theory or group of theories, providing brief biographies that shed light on how the theories were formed.

    It brings you clear coverage essential to understanding the clinical relevance of anatomical and physiological principles. Fully updated and written by respected veterinary technician educators, this popular textbook is the practical, comprehensive foundation for your success in veterinary technology.Clinical application boxes help you sharpen your skills and apply principles to practice.Test Yourself boxes throughout chapters emphasize important study points.An extensive glossary provides quick reference to hundreds of important terms and definitions.Over 300 new illustrations help you identify structures with rich, realistic clarity.A NEW full color format visually enhances your understanding of anatomic and physiologic concepts.Four NEW chapters give you the latest insight on the chemical basis of life, nutrition and metabolism, pregnancy, development, and lactation, and reptile and amphibian anatomy and physiology.A revised chapter on the cardiovascular system helps you most effectively comprehend the complex functions of the heart and blood vessels.

    Would you believe the one about the man who got stuck with half a paintbrush in a delicate area? The medical ethics of a woman using the hospital like a babysitting service? The day when two surgeons almost came to blows after a squabble over theatre space? After reading this brilliantly realised medical nonfiction collection of short stories you will no longer doubt the strange and sometimes tragic circumstances doctors face in medical diagnosis and treatment. From humourous stories about misbehaving patients to short biographies to moving medical stories with tragic ends, Dr Jay weaves a tale of over thirty years’ experience and relates some of the most interesting medical diagnosis and treatment of patients from his career. His narrative voice is rich and compelling and each of the patients’ short biographies is treated with the solid medical ethics we have come to expect from our doctors. Forthright and entertaining, this medical nonfiction collection of short stories comes directly from the horse’s mouth and includes humourous stories as well as short biographies that reveal some of the least pleasant aspects of life as a Surgeon.

    This text provides a basic treatment of discrete-event simulation, including the proper collection and analysis of data, the use of analytic techniques, verification and validation of models, and designing simulation experiments. It offers an up-to-date treatment of simulation of manufacturing and material handling systems, computer systems, and computer networks. Students and instructors will find a variety of resources at the associated website, www.bcnn.net, including simulation source code for download, additional exercises and solutions, web links and errata.

    Although necessary health care should be available to all who need it, he says, the current health-care debate assumes that everyone requires massive amounts of expensive care to stay healthy. Hadler urges that before we commit to paying for whatever pharmaceutical companies and the medical establishment tell us we need, American consumers need to adopt an attitude of skepticism and arm themselves with enough information to make some of their own decisions about what care is truly necessary. Each chapter of Worried Sick is an object lesson regarding the uses and abuses of a particular type of treatment, such as mammography, colorectal screening, statin drugs, or coronary stents. For consumers and medical professionals interested in understanding the scientific basis for Hadler's arguments, each topical chapter has an accompanying source chapter in which Hadler discusses the medical literature and studies that inform his critique. According to Hadler, a major stumbling block to rational health-care policy in the United States is contention over the very concept of what constitutes good health. By learning to distinguish good medical advice from persuasive medical marketing, consumers can make better decisions about their personal health and use that wisdom to inform their perspectives on health-policy issues.

    But his heart was failing. After months of waiting for a heart transplant, he died during the operation. Hours after his death, his wife Susan was asked a shocking question: would she donate her husband’s face to a total stranger?The stranger was James Maki, the adopted son of parents who spent part of World War II in an internment camp for Japanese Americans. Rebelling against his stern father, a professor, by enlisting to serve in Vietnam, he returned home a broken man, addicted to drugs. One night he fell facedown onto the electrified third rail of a Boston subway track.A young Czech surgeon who was determined to make a better life on the other side of the Iron Curtain was on call when the ambulance brought Maki to the hospital. Although Dr. Bohdan Pomahac gave him little chance of survival, Maki battled back. He was sober and grateful for a second chance, but he became a recluse, a man without a face. His only hope was a controversial face transplant, and Dr. Pomahac made it happen.In The Match, Susan Whitman Helfgot captures decades of drama and history, taking us from Warsaw to Japan, from New York to Hollywood. Through wars and immigration, poverty and persecution, from a medieval cadaver dissection to a stunning seventeen-hour face transplant, she weaves together the story of people forever intertwined—a triumphant legacy of hope.

    It gives clear descriptions of linear systems and uses mathematics not only to prove axiomatic theory, but also to enhance physical and intuitive understanding.

    The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    It invites both introductory and advanced students to appreciate the roots and limits of American exceptionalism, and to recognize the profound importance of current debates over the government's role in our everyday lives.

    "Introductory Chemistry, "Fourth Edition extends chemistry from the laboratory to your world, helping you learn chemistry by demonstrating how it is manifested in your daily life. Throughout, the Fourth Edition presents a new student-friendly, step-by-step problem-solving approach that adds four steps to worked examples (Sort, Strategize, Solve, and Check). This proven text continues to foster student success beyond the classroom with MasteringChemistry(R), the most advanced online tutorial and assessment program available. Note: This is the standalone book, if you want the book/access card order the ISBN below: 0321741021 / 9780321741028 Introductory Chemistry Plus MasteringChemistry with eText -- Access Card Package Package consists of: 0321687930 / 9780321687937 Introductory Chemistry 032173002X / 9780321730022 MasteringChemistry with Pearson eText -- Valuepack Access Card -- for Introductory Chemistry

    Supersized life spans are going to radically alter society, and present an unprecedented opportunity to change our approach not only to old age but to all of life’s stages. The ramifications are just beginning to dawn on us.... yet in the meantime, we keep thinking about, and planning for, life as it used to be lived. In A Long Bright Future, longevity and aging expert Laura Carstensen guides us into the new possibilities offered by a longer life. She debunks the myths and misconceptions about aging that stop us from adequately preparing for the future both as individuals and as a society: that growing older is associated with loneliness and unhappiness, and that only the genetically blessed live well and long. She then focuses on other important components of a long life, including finances, health, social relationships, Medicare and Social Security, challenging our preconceived notions of “old age” every step of the way.

    Writer, M.D. celebrates this rich tradition with a collection of fiction and nonfiction by today’s most beloved physician-writers, including,• Abraham Verghese, on the lost art of the physical exam• Pauline Chen, on the bond between a med student and her first cadaver• Atul Gawande, on the ethical dilemmas of a young surgical intern• Danielle Ofri, on the devastation of losing a patient• Ethan Canin, on love, poetry, and growing oldThese essays and stories illuminate the inner lives of men and women who deal with trauma, illness, mortality, and grief on a daily basis. Read together, they provide a candid, moving, one-of-a-kind glimpse behind the doctor’s mask.

    Is the apple sitting on your kitchen counter alive, or is only the apple tree it came from deserving of the word? If we can't answer that question here on earth, how will we know when and if we discover alien life on other worlds? The question hangs over some of society's most charged conflicts--whether a fertilized egg is a living person, for example, and when we ought to declare a person legally dead.Charting the obsession with Dr. Frankenstein's monster and how Coleridge came to believe the whole universe was alive, Zimmer leads us all the way into the labs and minds of researchers working on engineering life from the ground up.

    . . Sanghavi is a vivid and effortless teller of human tales and quite evidently a special doctor, too." —Atul Gawande, author of ComplicationsIn this compelling book, Dr. Darshak Sanghavi takes the reader on a dramatic tour of a child's eight vital organs, beginning with the lungs and proceeding through the heart, blood, bones, brain, skin, gonads, and gut.Along the way, we meet children and families in extraordinary circumstances—a premature baby named Adam Flax who was born with undeveloped lungs, a teenage boy with a positive pregnancy test, and a young girl who keeps losing weight despite her voracious appetite. In a deeply personal narrative, Sanghavi provides a richly detailed—and humanized—portrait of how the pediatric body functions in both sickness and health.

    Born and raised in a small town, they enjoy a close relationship, though each has her own tastes and personality. But the Hensels also share a body. Their two heads sit side-by-side on a single torso, with two arms and two legs. They have not only survived, but have developed into athletic, graceful young women. And that, writes Mark S. Blumberg, opens an extraordinary window onto human development and evolution.In Freaks of Nature, Blumberg turns a scientist's eye on the oddities of nature, showing how a subject once relegated to the sideshow can help explain some of the deepest complexities of biology. Why, for example, does a two-headed human so resemble a two-headed minnow? What we need to understand, Blumberg argues, is that anomalies are the natural products of development, and it is through developmental mechanisms that evolution works. Freaks of Nature induces a kind of intellectual vertigo as it upends our intuitive understanding of biology. What really is an anomaly? Why is a limbless human a freak, but a limbless reptile-a snake-a successful variation?What we see as deformities, Blumberg writes, are merely alternative paths for development, which challenge both the creature itself and our ability to fit it into our familiar categories. Rather than mere dead-ends, many anomalies prove surprisingly survivable-as in the case of the goat without forelimbs that learned to walk upright. Blumberg explains how such variations occur, and points to the success of the Hensel sisters and the goat as examples of the extraordinary flexibility inherent in individual development.In taking seriously a subject that has often been shunned as discomfiting and embarrassing, Mark Blumberg sheds new light on how individuals-and entire species-develop, survive, and evolve.