The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    This is the loose-leaf version of Educational Psychology by Anita Woolfolk.

    

    Digital Integrated Circuits maintains a consistent, logical flow of subject matter throughout. KEY TOPICS: Addresses today's most significant and compelling industry topics, including: the impact of interconnect, design for low power, issues in timing and clocking, design methodologies, and the tremendous effect of design automation on the digital design perspective. MARKET: For readers interested in digital circuit design.

    It also includes a major study on suicide and case studies.

    Paul Farmer, a physician and anthropologist with twenty years of experience working in Haiti, Peru, and Russia, argues that promoting the social and economic rights of the world’s poor is the most important human rights struggle of our times. With passionate eyewitness accounts from the prisons of Russia and the beleaguered villages of Haiti and Chiapas, this book links the lived experiences of individual victims to a broader analysis of structural violence. Farmer challenges conventional thinking within human rights circles and exposes the relationships between political and economic injustice, on one hand, and the suffering and illness of the powerless, on the other.Farmer shows that the same social forces that give rise to epidemic diseases such as HIV and tuberculosis also sculpt risk for human rights violations. He illustrates the ways that racism and gender inequality in the United States are embodied as disease and death. Yet this book is far from a hopeless inventory of abuse. Farmer’s disturbing examples are linked to a guarded optimism that new medical and social technologies will develop in tandem with a more informed sense of social justice. Otherwise, he concludes, we will be guilty of managing social inequality rather than addressing structural violence. Farmer’s urgent plea to think about human rights in the context of global public health and to consider critical issues of quality and access for the world’s poor should be of fundamental concern to a world characterized by the bizarre proximity of surfeit and suffering.

    In this timely, practical guide, Diane Heacox presents a menu of strategies and tools any teacher can use to differentiate instruction in any curriculum, even a standard of mandated curriculum. Drawing on Bloom's Taxonomy, Gardner's multiple Intelligences, other experts in the field, and her own considerable experience in the classroom, she explains how to differentiate instruction across a broad spectrum of scenarios. Some strategies are quick and easy others are more comprehensive. Templates and forms simplify planning; examples illustrate differentiation in many content areas. Recommended for all teachers committed to reaching and teaching all learners.

    Designed primarily for undergraduates, this self-help manual offers straightforward solutions to common problems and an overview of the diversity of writing tasks faced by professional biologists.

    Her writing style and consistent use of examples and case studies results in a text that undergraduates students will find easy to understand.

    With millions of copies sold, the Publication Manual of the American Psychological Association is the style manual of choice for writers, editors, students, educators, and professionals in psychology, sociology, business, economics, nursing, social work, and justice administration, and other disciplines in which effective communication with words and data is fundamental.In addition to providing clear guidance on grammar, the mechanics of writing, and APA style, the Publication Manual offers an authoritative and easy-to-use reference and citation system and comprehensive coverage of the treatment of numbers, metrication, statistical and mathematical data, tables, and figures for use in writing, reports, or presentations. The new edition has been revised and updated to include: The latest guidelines and examples for referencing electronic and online sources New and revised guidelines for submitting papers electronically Improved guidelines for avoiding plagiarism Simplified formatting guidelines for writers using up-to-date word-processing software All new guidelines for presenting case studies Improved guidelines for the construction of tables Updates on copyright and permissions issues for writers New reference examples for audiovisual media and patents An expanded and improved index for quick and easy access Writers, scholars, and professionals will also find: New guidelines on how to choose text, tables, or figures to present data Guidelines for writing cover letters for submitting articles for publication, plus a sample letter Expanded guidelines on the retention of raw data New advice on establishing written agreements for the use of shared data New information on the responsibilities of co-authors New and experienced readers alike will find the 5th Edition a complete resource for writing, presenting, or publishing with clarity and persuasiveness.Approximately 400 pages

    This is a lively overview of the major ideas and concepts in archaeological theory.

    Contains 3000 solved problems with solutions, solved problems; an index to help you quickly locate the types of problems you want to solve; problems like those you'll find on your exams; techniques for choosing the correct approach to problems; and guidance toward efficient solutions.

    Known for its carefully developed, thoroughly integrated, step-by-step approach to problem solving, General Chemistry helps students master quantitative skills and build a lasting conceptual understanding of key chemical concepts. The Ninth Edition retains this hallmark approach and builds upon the conceptual focus through key new features and revisions.

    It develops an understanding of function and evolution into the discussion of anatomy of the various systems.

     Four interwoven themes support the major recent developments in the rapidly changing field of biopsychology. Thousands of new references and dozens of new topics have been added to this edition, making Pinel's discussion of and focus on the human element easy and interesting to read. For those interested in physiological and biological psychology.