The first volume in this annual series of the best writing by Americans, meticulously selected by bestselling author James Gleick, one of the foremost chronicles of scientific social history, debuts with a stellar collection of writers and thinkers.  Many of these cutting-edge essays offer glimpses of new realms of discovery and thought, exploring territory that is unfamiliar to most of us, or finding the unexpected in the midst of the familiar.  Nobel Laureate physicist Steven Weinberg challenges the idea of whether the universe has a designer; Pulitzer Prize winner Natalie Angier reassesses caveman (and-woman) couture; bestselling author and Darwinian theorist Stephen Jay Gould makes a claim for the man whose ideas Darwin discredited; Timothy Ferris proposes a realistic alternative to wrap-speed interseller travel; neurologist and bestselling author Oliver Sacks reminisces about his first loves-chemistry and math.  This diverse, stimulating and accessible collection is required reading for anyone who wants to travel to the frontier of knowledge.

    In One Renegade Cell, Weinberg presents a state-of-the-art account of how cancer begins and how, one day, it will be cured.

    As a sympathetic brain detective, Klawans deduced a great deal from his patients, not only about the immediate causes of their ailments but also about the evolutionary underpinnings of their behaviour.

    Primarily, a dichotomy exists between naturalists who deny the supernatural and insist upon scientific explanations for all accounts, and mystics who attribute every unusual sighting to paranormal activity. The common thread is that both sides attempt to fit the unknown into their own paradigm.People everywhere are looking for honest answers. As believers, we have another mandate. We do not simply find an idea or train of thought that is suitable to our sensibilities. We neither shy away from the supernatural because it is unsettling nor condemn scientific explanations for their lack of spirituality. Rather, we search for truth.In Lights in the Sky and Little Green Men, the authors have initiated a search for truth to answers about UFO sightings and extraterrestrial life. Utilizing extensive scientific background and knowledge of the Scriptures, they approach questions like: -- Could life exist on other planets?-- If extraterrestrials exist, is it possible for them to travel to Earth?-- Should reports of alien contact and abductions be dismissed?When we have medical questions, we seek answers from qualified medical professionals. Likewise, when we have questions about UFO and extraterrestrial phenomena, we should seek answers from qualified sources. Authors Hugh Ross, Kenneth Samples, and Mark Clark have training and experience in the appropriate disciplines. They augment scientific and historical analysis with truths from God's Word to provide a balanced look at a controversial subject.

    In his hallmark friendly style, he explores the universal impact of being the right size. By examining stories ranging from Alice in Wonderland to Gulliver's Travels, he shows that humans have always been fascinated by things big and small. Why then does size always reside on the fringes of science and never on the center stage? Why do biologists and others ponder size only when studying something else--running speed, life span, or metabolism? Why Size Matters, a pioneering book of big ideas in a compact size, gives size its due by presenting a profound yet lucid overview of what we know about its role in the living world. Bonner argues that size really does matter--that it is the supreme and universal determinant of what any organism can be and do. For example, because tiny creatures are subject primarily to forces of cohesion and larger beasts to gravity, a fly can easily walk up a wall, something we humans cannot even begin to imagine doing.Bonner introduces us to size through the giants and dwarfs of human, animal, and plant history and then explores questions including the physics of size as it affects biology, the evolution of size over geological time, and the role of size in the function and longevity of living things.As this elegantly written book shows, size affects life in its every aspect. It is a universal frame from which nothing escapes.

    Designed primarily for undergraduates, this self-help manual offers straightforward solutions to common problems and an overview of the diversity of writing tasks faced by professional biologists.

    It isn't surprising then that Koestler should hark back to the opprobrious case of Dr Paul Kammerer, an Austrian biologist whose controversial experiments on the evolutionary process (using among other amphibians the midwife toad, so named for its mating habits) were denounced as fraudulent in 1926 by an American herpetologist, G.K. Noble, in the pages of Nature-- whereupon Kammerer blew his brains out, seemingly confirming the old saw "confession is suicide & suicide is confession." But Koestler's investigation, begun as a study of a scientist who betrayed his commitment to truth, indicates that Kammerer, far from being a laboratory quisling, was probably innocent; a victim of an unknown colleague's machinations to discredit his work & therefore in the larger sense a casualty of the still unresolved war between the nco-Darwinist evolutionists who support the random mutation theory & the heretical Lamarckians who maintain (as did Kammerer's experiments) that acquired characteristics can be transmitted from one generation to another. "I did not start with the intention to rehabilitate Paul Kammerer," says Koestler, "but I ended up with an attempt to do so." In the course of that effort he uses his skill as both inventive fantast & experienced researcher to give the midwife toad case a sense of drama & veracity. Those who found The Double Helix satisfying will enjoy this one too, no matter if they agree with Koestler's conclusions.--Kirkus (edited)

    Just a half century ago, this idea was revolutionary. In April 1953, James Watson and Francis Crick published in Nature their groundbreaking work revealing the double helix structure of DNA. While this discovery received wide attention from both mainstream media and the academic community, it was just one part of the bigger story in this history of molecular biology. By the mid-1950s, the scientific community confirmed that genes were indeed comprised of DNA; they just needed to crack the genetic code—and the race was on. Life’s Greatest Secret is the full and rich history of this challenge and the characters—many of whom were not biologists—whose work contributed to this grand scientific endeavor: mathematician and father of cybernetics Norbert Wiener, physicist Erwin Schrödinger, information theorist Claude Shannon, and biologists Jacques Monod and Marshall Nirenberg.In Life’s Greatest Secret, science historian and zoologist Matthew Cobb shows that the race to crack the genetic code was mostly a matter of craft—individuals or small groups struggling with ideas and concepts as much as they were with facts, trying to find the right experiment to answer the right questions, even if they didn’t know what the questions were, and finding that, even when the most definitive answer served mostly to reveal more ignorance, whether in 1953, with Watson and Crick, or in 1961, when Nirenberg and Matthaei showed how DNA codes for specific amino acids, and again and again thereafter, or in 2000, with the first publication of a human genome. Each discovery was a leap forward in our understanding of the natural world and our place within in, akin to the discoveries of Galileo and Einstein in the realm of physics, or the publication of Darwin’s On the Origin of Species. And each served to show how much bigger the problem was that anyone had previously imagined, a trend that continues, as Cobb shows, even today, whether we are discussing gene regulation, epigenetics, or GMOs.Life’s Greatest Secret is a story of ideas and of experimentation, of ingenuity, insight, and dead-ends, in the hunt to make the greatest discovery of twentieth century biology. Ultimately, though, this is a story of humans exploring what it is that makes us human.

    Destined to be a landmark apologetic work, The Cell's Design explores the full scientific and theological impact of these discoveries. Instead of focusing on the inability of natural processes to generate life's chemical systems (as nearly all apologetics works do), Fazale Rana makes a positive case for life's supernatural basis by highlighting the many biochemical features that reflect the Creator's hallmark signature.This breakthrough work extends the case for design beyond irreducible complexity. These never-before-discussed evidences for design will evoke awe and amazement at God's creative majesty in the remarkable elegance of the cell's chemistry.

    Geared to philosophers, biologists, and students of both, the book provides sophisticated and innovative coverage of the central topics and many of the latest developments in the field. Emphasizing connections between biological theories and other areas of philosophy, and carefully explaining both philosophical and biological terms, Peter Godfrey-Smith discusses the relation between philosophy and science; examines the role of laws, mechanistic explanation, and idealized models in biological theories; describes evolution by natural selection; and assesses attempts to extend Darwin's mechanism to explain changes in ideas, culture, and other phenomena. Further topics include functions and teleology, individuality and organisms, species, the tree of life, and human nature. The book closes with detailed, cutting-edge treatments of the evolution of cooperation, of information in biology, and of the role of communication in living systems at all scales.Authoritative and up-to-date, this is an essential guide for anyone interested in the important philosophical issues raised by the biological sciences.

    Our instincts—for food, sex, or territorial protection— evolved for life on the savannahs 10,000 years ago, not in today’s world of densely populated cities, technological innovations, and pollution. We now have access to a glut of larger-than-life objects, from candy to pornography to atomic weapons—that gratify these gut instincts with often-dangerous results. Animal biologists coined the term “supernormal stimuli” to describe imitations that appeal to primitive instincts and exert a stronger pull than real things, such as soccer balls that geese prefer over eggs. Evolutionary psychologist Deirdre Barrett applies this concept to the alarming disconnect between human instinct and our created environment, demonstrating how supernormal stimuli are a major cause of today’s most pressing problems, including obesity and war. However, Barrett does more than show how unfettered instincts fuel dangerous excesses. She also reminds us that by exercising self-control we can rein them in, potentially saving ourselves and civilization. 55 illustrations.

    Here, Michael Tomasello proposes a complementary theory of human uniqueness, focused on development. Building on the seminal ideas of Vygotsky, his data-driven model explains how those things that make us most human are constructed during the first years of a child's life.Tomasello assembles nearly three decades of experimental work with chimpanzees, bonobos, and human children to propose a new framework for psychological growth between birth and seven years of age. He identifies eight pathways that starkly differentiate humans from their closest primate relatives: social cognition, communication, cultural learning, cooperative thinking, collaboration, prosociality, social norms, and moral identity. In each of these, great apes possess rudimentary abilities. But then, Tomasello argues, the maturation of humans' evolved capacities for shared intentionality transform these abilities--through the new forms of sociocultural interaction they enable--into uniquely human cognition and sociality. The first step occurs around nine months, with the emergence of joint intentionality, exercised mostly with caregiving adults. The second step occurs around three years, with the emergence of collective intentionality involving both authoritative adults, who convey cultural knowledge, and coequal peers, who elicit collaboration and communication. Finally, by age six or seven, children become responsible for self-regulating their beliefs and actions so that they comport with cultural norms.Becoming Human places human sociocultural activity within the framework of modern evolutionary theory, and shows how biology creates the conditions under which culture does its work.

    In recent years, opponents of "Darwin’s dangerous idea" have mounted history’s most sophisticated and generously funded attack, claiming that evolution is "a theory in crisis." Ironically, these claims are being made at a time when the explosion of information from genome projects has revealed the most compelling and overwhelming evidence of evolution ever discovered. Much of the latest evidence of human evolution comes not from our genes, but from so-called "junk DNA," leftover relics of our evolutionary history that make up the vast majority of our DNA. Relics of Eden explores this powerful DNA-based evidence of human evolution. The "relics" are the millions of functionally useless but scientifically informative remnants of our evolutionary ancestry trapped in the DNA of every person on the planet. For example, the analysis of the chimpanzee and Rhesus monkey genomes shows indisputable evidence of the human evolutionary relationship with other primates. Over 95 percent of our genome is identical with that of chimpanzees and we also have a good deal in common with other animal species. Author Daniel J. Fairbanks also discusses what DNA analysis reveals about where humans originated. The diversity of DNA sequences repeatedly confirms the archeological evidence that humans originated in sub-Saharan Africa (the "Eden" of the title) and from there migrated through the Middle East and Asia to Europe, Australia, and the Americas. In conclusion, Fairbanks confronts the supposed dichotomy between evolution and religion, arguing that both science and religion are complementary ways to seek truth. He appeals to the vast majority of Americans who hold religious convictions not to be fooled by the pseudoscience of Creationists and Intelligent Design advocates and to abandon the false dichotomy between religion and real science. This concise, very readable presentation of recent genetic research is completely accessible to the nonspecialist and makes for enlightening and fascinating reading.

    As a believing scientist, Teilhard wrestled with the problem of presenting to the believer a scientific picture that would enlarge his religious vision and to the scientist a statement of religious ideas that would integrate with his understanding of reality. Foreword by N. M. Wildiers; Index. Translated by René Hague.A Helen and Kurt Wolff Book

    The germ revolution came after two decades of scientific virtuosity, outstanding feats of intellectual courage and bitter personal rivalries, doctors at last recognised that infectious diseases are caused by mircoscopic organisms.