From Mary Lamb, sister of Charles, who in the throes of a nervous breakdown turned on her mother with a kitchen knife, to Freud, Jung, and Lacan, who developed the new women-centered therapies, Lisa Appignanesi’s research traces how more and more of the inner lives and emotions of women have become a matter for medics and therapists. Here too is the story of how over the years symptoms and diagnoses have developed together to create fashions in illness and how treatments have succeeded or sometimes failed. Mad, Bad, and Sad takes us on a fascinating journey through the fragile, extraordinary human mind.

    Its story, however, extends deep into prehistory: the earliest Andean cultures depicted mescaline-containing cacti in their temples.   Mescaline was isolated in 1897 from the peyote cactus, first encountered by Europeans during the Spanish conquest of Mexico. During the twentieth century it was used by psychologists investigating the secrets of consciousness, spiritual seekers from Aleister Crowley to the president of the Church of Jesus Christ of Latter-day Saints, artists exploring the creative process, and psychiatrists looking to cure schizophrenia. Meanwhile peyote played a vital role in preserving and shaping Native American identity. Drawing on botany, pharmacology, ethnography, and the mind sciences and examining the mescaline experiences of figures from William James to Walter Benjamin to Hunter S. Thompson, this is an enthralling narrative of mescaline’s many lives.

    Miller, is the most significant chemical substance mankind has ever encountered. So ancient that remains of poppies have been found in Neolithic tombs, it is the most effective drug ever discovered for treating pain. Whatever advances are made in medicine, Miller adds, nothing could really be more important than that. And yet, when it comes to mind-altering substances, morphine is only a cc or two in a vast river that flows through human civilization, ranging LSD to a morning cup of tea.In DRUGGED, Miller takes readers on an eye-opening tour of psychotropic drugs, describing the various kinds, how they were discovered and developed, and how they have played multiple roles in virtually every culture. The vast scope of chemicals that cross the blood-brain barrier boggle the very brain they reach: cannabis and cocaine, antipsychotics and antidepressants, alcohol, amphetamines, and Ecstasy-and much more. Literate and wide-ranging, Miller weaves together science and history, telling the story of the undercover theft of 20,000 tea plants from China by a British spy, for example, the European discovery of coffee and chocolate, and how James Wolfgang von Goethe, the famous man of letters, first isolated the alkaloid we now know as caffeine. Miller explains what scientists know-and don't-about the impact of each drug on the brain, down to the details of neurotransmitters and their receptors. He clarifies the differences between morphine and heroin, mescaline and LSD, and other similar substances. Drugged brims with surprises, revealing the fact that antidepressant drugs evolved from the rocket fuel that shot V2 rockets into London during World War II, highlighting the role of hallucinogens in the history of religion, and asking whether Prozac can help depressed cats.Entertaining and authoritative, Drugged is a truly fascinating book.

    Confusing messages from health authorities and ineffective treatments have left many people desperate for reliable solutions. An enormous alternative industry is filling the void, selling products that are often of questionable safety and totally unknown effectiveness.In Clean, doctor and journalist James Hamblin explores how we got here, examining the science and culture of how we care for our skin today. He talks to dermatologists, microbiologists, allergists, immunologists, aestheticians, bar-soap enthusiasts, venture capitalists, Amish people, theologians, and straight-up scam artists, trying to figure out what it really means to be clean. He even experiments with giving up showers entirely, and discovers that he is not alone.Along the way he realizes that most of our standards of cleanliness are less related to health than most people think. A major part of the picture has been missing: a little-known ecosystem known as the skin microbiome--the trillions of microbes that live on our skin and in our pores. These microbes are not dangerous; they're more like an outer layer of skin that no one knew we had, and they influence everything from acne, eczema, and dry skin to how we smell. The new goal of skin care will be to cultivate a healthy biome--and to embrace the meaning of "clean" in the natural sense. This can mean doing much less, saving time, money, energy, water, and plastic bottles in the process.Lucid, accessible, and deeply researched, Clean explores the ongoing, radical change in the way we think about our skin, introducing readers to the emerging science that will be at the forefront of health and wellness conversations in coming years.

    Roger Ekirch illuminates the aspects of life most often overlooked by other historians—those that unfold at night. In this "triumph of social history" (Mail on Sunday), Ekirch's "enthralling anthropology" (Harper's) exposes the nightlife that spawned a distinct culture and a refuge from daily life.Fear of crime, of fire, and of the supernatural; the importance of moonlight; the increased incidence of sickness and death at night; evening gatherings to spin wool and stories; masqued balls; inns, taverns, and brothels; the strategies of thieves, assassins, and conspirators; the protective uses of incantations, meditations, and prayers; the nature of our predecessors' sleep and dreams—Ekirch reveals all these and more in his "monumental study" (The Nation) of sociocultural history, "maintaining throughout an infectious sense of wonder" (Booklist).

    Many books on the plague rely on statistics to tell the story: how many people died; how farm output and trade declined. But statistics can’t convey what it was like to sit in Siena or Avignon and hear that a thousand people a day are dying two towns away. Or to have to chose between your own life and your duty to a mortally ill child or spouse. Or to live in a society where the bonds of blood and sentiment and law have lost all meaning, where anyone can murder or rape or plunder anyone else without fear of consequence.In The Great Mortality, author John Kelly lends an air of immediacy and intimacy to his telling of the journey of the plague as it traveled from the steppes of Russia, across Europe, and into England, killing 75 million people—one third of the known population—before it vanished.

    Is it possible to catch autism or OCD the same way we catch the flu? Can a child's contact with cat litter lead to schizophrenia? In her eye-opening new book, National Book Critics Circle Award-winning author Harriet Washington reveals that we can in fact "catch" mental illness. In INFECTIOUS MADNESS, Washington presents the new germ theory, which posits not only that many instances of Alzheimer's, OCD, and schizophrenia are caused by viruses, prions, and bacteria, but also that with antibiotics, vaccinations, and other strategies, these cases can be easily prevented or treated. Packed with cutting-edge research and tantalizing mysteries, INFECTIOUS MADNESS is rich in science, characters, and practical advice on how to protect yourself and your children from exposure to infectious threats that could sabotage your mental and physical health.

    It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes.This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history – the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our children.Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and future.

    Lieberman illuminates how these ongoing changes have brought many benefits, but also have created novel conditions to which our bodies are not entirely adapted, resulting in a growing incidence of obesity and new but avoidable diseases, including type-2 diabetes. He proposes that many of these chronic illnesses persist and in some cases are intensifying because of "dysevolution," a pernicious dynamic whereby only the symptoms rather than the causes of these maladies are treated. And finally—provocatively—he advocates the use of evolutionary information to help nudge, push, and sometimes oblige us to create a more salubrious environment.(With charts and line drawings throughout.)From the Hardcover edition.

    Based on fifteen years of research into energy medicine, Dr. Myss's work shows how every illness corresponds to a pattern of emotional and psychological stresses, beliefs, and attitudes that have influenced corresponding areas of the human body. Anatomy of the Spirit also presents Dr. Myss's breakthrough model of the body's seven centers of spiritual and physical power, in which she synthesizes the ancient wisdom of three spiritual traditions-the Hindu chakras, the Christian sacraments, and the Kabbalah's Tree of Life-to demonstrate the seven stages through which everyone must pass in the search for higher consciousness and spiritual maturity. With this model, Dr. Myss shows how you can develop your own latent powers of intuition as you simultaneously cultivate your personal power and spiritual growth.By teaching you to see your body and spirit in a new way, Anatomy of the Spirit provides you with the tools for spiritual maturity and physical wholeness that will change your life.

    Today, you can order any conceivable pill or powder with the click of a mouse. In Drugs Unlimited, Mike Power tells the tale of drugs in the Internet Age, in which users have outmaneuvered law enforcement, breached international borders, and created a massive worldwide black market.But the online market in narcotics isn't just changing the way drugs are bought and sold; it's changing the nature of drugs themselves. Enterprising dealers are using the Web to engage highly skilled foreign chemists to tweak the chemical structures of banned drugs—just enough to create a similar effect and just enough to render them legal in most parts of the world. Drugs are marketed as "not for human consumption," but everyone knows exactly how they're going to be used—what they can't know is whether their use might prove fatal.From dancefloors to the offices of apathetic government officials, via social networking sites and underground labs, Power explores this agile, international, virtual subculture that will always be one step ahead of the law.

    He was a successful psychologist and writer, with books to his name and bylines in major magazines. But none of that mattered. The impulse to take his own life remained. At times it felt all but inescapable.   Bering survived. And in addition to relief, the fading of his suicidal thoughts brought curiosity. Where had they come from? Would they return? Is the suicidal impulse found in other animals? Or is our vulnerability to suicide a uniquely human evolutionary development? In Suicidal, Bering answers all these questions and more, taking us through the science and psychology of suicide, revealing its cognitive secrets and the subtle tricks our minds play on us when we’re easy emotional prey. Scientific studies, personal stories, and remarkable cross-species comparisons come together to help readers critically analyze their own doomsday thoughts while gaining broad insight into a problem that, tragically, will most likely touch all of us at some point in our lives. But while the subject is certainly a heavy one, Bering’s touch is light. Having been through this himself, he knows that sometimes the most effective response to our darkest moments is a gentle humor, one that, while not denying the seriousness of suffering, at the same time acknowledges our complicated, flawed, and yet precious existence.   Authoritative, accessible, personal, profound—there’s never been a book on suicide like this. It will help you understand yourself and your loved ones, and it will change the way you think about this most vexing of human problems.

    This is the ground-breaking theory explored in Mortals.The ground-breaking book that uncovers how our fear of death is the hidden driver of most of humankind's endeavours.The human mind can grapple with the future, visualising and calculating solutions to complex problems, giving us tremendous advantages over other species throughout our evolution. However, this capability comes with a curse. By five to ten years of age, all humans know where they are heading: to the grave.In Mortals, Rachel Menzies and Ross Menzies, both acclaimed psychologists whose life's work has focused on death anxiety, examine all the major human responses to death across history. From the development of religious systems denying the finality of death, to 'immortality projects' involving enduring art, architecture and literature, some of the consequences of our fear of death have been glorious while others have been destructive, leading to global conflicts and genocide.Looking forward, Mortals hypothesises that worse could be to come-our unconscious dread of death has led to rampant consumerism and overpopulation, driving the global warming and pandemic crises that now threaten our very existence. In a terrible irony, Homo sapiens may ultimately be destroyed by our knowledge of our own mortality.

    Days earlier, she had been on the threshold of a new, adult life: at the beginning of her first serious relationship and a promising career at a major New York newspaper. Now she was labeled violent, psychotic, a flight risk. What happened?In a swift and breathtaking narrative, Cahalan tells the astonishing true story of her descent into madness, her family’s inspiring faith in her, and the lifesaving diagnosis that nearly didn’t happen.

    Susan Wicklund chronicles her emotional and dramatic twenty-year career on the front lines of the abortion war. Growing up in working class, rural Wisconsin, Wicklund had her own painful abortion at a young age. It was not until she became a doctor that she realized how many women shared her ordeal of an unwanted pregnancy—and how hidden this common experience remains. This is the story of Susan's love for a profession that means listening to women and helping them through one of the most pivotal and controversial events in their lives. Hers is also a calling that means sleeping on planes and commuting between clinics in different states—and that requires her to wear a bulletproof vest and to carry a .38 caliber revolver. This is also the story of the women whom Susan serves, women whose options are increasingly limited.Through these intimate, complicated, and inspiring accounts, Wicklund reveals the truth about the women's clinics that anti-abortion activists portray as little more than slaughterhouses for the unborn. As we enter the most fevered political fight over abortion America has ever seen, this raw and powerful memoir shows us what is at stake.