Illuminating, completely engaging—it's essential reading for all since we all know someone whose life, family or friends are touched by the disease that directly afflicts a fifth of Canadians. In her early twenties, while outwardly thriving in her dream job and enjoying warm familial support and a strong social network, award-winning journalist Anna Mehler Paperny found herself trapped by feelings of failure and despair. Her first suicide attempt—ingesting a deadly mix of sleeping pills and antifreeze—landed her in the ICU, followed by weeks of enforced detention that ran the gamut of horrifying, boring, hilarious, and absurd. This was Anna's entry into the labyrinthine psychiatric care system responsible for providing care to millions of Canadians.As she struggled to survive the psych ward and as an outpatient—enduring the "survivor's" shame of facing concerned family, friends, and co-workers; finding (or not) the right therapist, the right meds; staying healthy, insured, and employed—Anna could not help but turn her demanding journalist's eye on her condition and on the system in which she found herself. She set off on a quest to "know her enemy," interviewing leading practitioners in the field across Canada and the US—from psychiatrists to neurological experts, brain-mapping pioneers to heroic family practitioners, and others dabbling in novel hypotheses. She reveals in courageously frank detail her own experiences with the pharmacological pitfalls and side effects of long-term treatment, and offers moving case studies of conversations with others, opening wide a window into how we treat (and fail to treat) the disease that accounts for more years swallowed up by disability than any other in the world.

    As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    "No rock critic-living or dead, American or otherwise-has ever written about pop music with the evocative, hyperpoetic perfectitude of Rob Sheffield." So said Chuck Klosterman about Love is a Mix Tape, Sheffield's paean to a lost love via its soundtrack. Now, in Talking to Girls About Duran Duran, Sheffield shares the soundtrack to his eighties adolescence. When he turned 13 in 1980, Rob Sheffield had a lot to learn about women, love, music and himself, and in Talking to Girls About Duran Duran we get a glimpse into his transformation from pasty, geeky "hermit boy" into a young man with his first girlfriend, his first apartment, and a sense of the world. These were the years of MTV and John Hughes movies; the era of big dreams and bigger shoulder pads; and, like any all-American boy, this one was searching for true love and maybe a cooler haircut. It's all here: Inept flirtations. Dumb crushes. Deplorable fashion choices. Members Only jackets. Girls, every last one of whom seems to be madly in love with the bassist of Duran Duran. Sheffield's coming-of-age story is one that we all know, with a playlist that any child of the eighties or anyone who just loves music will sing along with. These songs-and Sheffield's writing-will remind readers of that first kiss, that first car, and the moments that shaped their lives.

    He was killed by a roadside bomb on October 14, 2006. His son, Jordan, was seven months old.Inspired by his example, Dana was determined to preserve his memory for their son. A Journal for Jordan is a mother's fiercely honest letter to her child about the parent he lost before he could even speak. It is also a father's advice and prayers for the son he will never know.A father figure to the soldiers under his command, Charles moved naturally into writing to his son. In neat block letters, he counseled him on everything from how to withstand disappointment and deal with adversaries to how to behave on a date. And he also wrote, from his tent, of recovering a young soldier's body, piece by piece, from a tank--and the importance of honoring that young man's life. He finished the journal two months before his death while home on a two-week leave, so intoxicated with love for his infant son that he barely slept.This is also the story of Dana and Charles together--two seemingly mismatched souls who loved each other deeply and lost each other too soon. A Journal for Jordan is a tender introduction, a loving good-bye, a reporter's inquiry into her soldier's life, and a heartrending reminder of the human cost of war.

    Now Pollan turns his sharp insight to the craft of building, as he recounts the process of designing and constructing a small one-room structure on his rural Connecticut property--a place in which he hoped to read, write and daydream, built with his two own unhandy hands.Invoking the titans of architecture, literature and philosophy, from Vitrivius to Thoreau, from the Chinese masters of feng shui to the revolutionary Frank Lloyd Wright, Pollan brilliantly chronicles a realm of blueprints, joints and trusses as he peers into the ephemeral nature of "houseness" itself. From the spark of an idea to the search for a perfect site to the raising of a ridgepole, Pollan revels in the infinitely detailed, complex process of creating a finished structure. At once superbly written, informative and enormously entertaining, A Place of My Own is for anyone who has ever wondered how the walls around us take shape--and how we might shape them ourselves.A Place of My Own recounts his two-and-a-half-year journey of discovery in an absorbing narrative that deftly weaves the day-to-day work of design and building--from siting to blueprint, from the pouring of foundations to finish carpentry--with reflections on everything form the power of place to shape our lives to the question of what constitutes "real work" in a technological society.A book about craft that is itself beautifully crafted, linking the world of the body and material things with the realm of mind, heart, and spirit, A Place of My Own has received extraordinary praise.

    Three weeks later, John's cousin Anthony Radziwill died of cancer. In this moving and candid memoir, Carole Radziwill, Anthony's widow, tells her story.

    Her beautiful mother was a saint who would swiftly correct anyone’s notion that deaf equaled dumb. Her handsome father, on the other hand, was more likely to be found hanging out with the sinners. Strong, gregarious, and hardworking, he managed to turn a wild plot of land into a family homestead complete with running water and electricity. To Kambri, he was Daniel Boone, Frank Lloyd Wright, Ben Franklin, and Elvis all rolled into one. But if Kambri’s dad was Superman, then the hearing world was his kryptonite. The isolation that accompanied his deafness unlocked a fierce temper—a rage that a teenage Kambri witnessed when he attacked her mother, and that culminated fourteen years later in his conviction for another violent crime.  With a smart mix of brutal honesty and blunt humor, Kambri Crews explores her complicated bond with her father—which begins with adoration, moves to fear, and finally arrives at understanding—as she tries to forge a new connection between them while he lives behind bars. Burn Down the Ground is a brilliant portrait of living in two worlds—one hearing, the other deaf; one under the laid-back Texas sun, the other within the energetic pulse of New York City; one mired in violence, the other rife with possibility—and heralds the arrival of a captivating new voice.

    Hilarious, horrifying and heartbreaking, this diary is everything you wanted to know – and more than a few things you didn't – about life on and off the hospital ward. As seen on ITV's Zoe Ball Book Club This edition includes extra diary entries and a new afterword by the author.

    From Comic Strip to Comic Relief, from Bolly-swilling Edina in Ab Fab to her takes on Madonna or Mamma Mia, her characters are household names.But it's Jennifer herself who has a place in all our hearts. This is her funny, moving and frankly bonkers memoir, filled with laughter, friends and occasional heartache - but never misery.BONKERS is full of riotous adventures: accidentally enrolling on a teacher training course with a young Dawn French, bluffing her way to each BBC series, shooting Lulu, trading wild faxes with Joanna Lumley, touring India with Ruby Wax and Goldie Hawn.There's cancer, too, when she becomes 'Brave Jen'. But her biggest battle is with the bane of her life: the Laws of Procrastination. As she admits, 'There has never been a Plan. Everything has been fairly random, happened by accident or just fallen into place. I'm off now, to do some sweeping...'Prepare to chuckle, whoop, and go BONKERS.

    Paul's School recently came under state investigation after extensive reports of sexual abuse on campus, Lacy Crawford thought she'd put behind her the assault she'd suffered at St. Paul's decades before, when she was fifteen. Still, when detectives asked for victims to come forward, she sent a note.Her criminal case file reopened, she saw for the first time evidence that corroborated her memories. Here were depictions of the naïve, hard-working girl she'd been, a chorister and debater, the daughter of a priest; of the two senior athletes who assaulted her and were allowed to graduate with awards; and of the faculty, doctors, and priests who had known about Crawford's assault and gone to great lengths to bury it.Now a wife, mother, and writer living on the other side of the country, Crawford learned that police had uncovered astonishing proof of an institutional silencing years before, and that unnamed powers were still trying to block her case. The slander, innuendo, and lack of adult concern that Crawford had experienced as a student hadn't been imagined as the effects of trauma, after all: these were the actions of a school that prized its reputation above anything, even a child.This revelation launched Crawford on an extraordinary inquiry into the ways gender, privilege, and power shaped her experience as a girl at the gates of America's elite. Her investigation looks beyond the sprawling playing fields and soaring chapel towers of crucibles of power like St. Paul's, whose reckoning is still to come. And it runs deep into the channels of shame and guilt, witness and silencing, that dictate who can speak and who is heard in American society.An insightful, mature, beautifully written memoir, Notes on a Silencing is an arresting coming-of-age story that wrestles with an essential question for our time: what telling of a survivor's story will finally force a remedy?

    In riveting first-person prose, Dr. Brendan Reilly takes us to the front lines of medicine today. Whipsawed by daily crises and frustrations, Reilly must deal with several daunting challenges simultaneously: the extraordinary patients under his care on the teeming wards of a renowned teaching hospital; the life-threatening illnesses of both of his ninety-year-old parents; and the tragic memory of a cold case from long ago that haunts him still. As Reilly’s patients and their families survive close calls, struggle with heartrending decisions, and confront the limits of medicine’s power to cure, One Doctor lays bare a fragmented, depersonalized, business-driven health-care system where real caring is hard to find. Every day, Reilly sees patients who fall through the cracks and suffer harm because they lack one doctor who knows them well and relentlessly advocates for their best interests.Filled with fascinating characters in New York City and rural New England — people with dark secrets, mysterious illnesses, impossible dreams, and many kinds of courage — One Doctor tells their stories with sensitivity and empathy, reminding us of professional values once held dear by all physicians. But medicine has changed enormously during Reilly’s career, for both better and worse, and One Doctor is a cautionary tale about those changes. It is also a hopeful, inspiring account of medicine’s potential to improve people’s lives, Reilly’s quest to understand the "truth" about doctoring, and a moving testament to the difference one doctor can make.

    The last thing his parents expected was to see him come alive.What followed was a remarkable tale of inspiration, heartbreak, dedication and joy as Benjamin's family relocated from Seattle to Orlando in order to capture that magic and put it to practical use. Amidst the daily challenges of life for an autistic child, Benjamin's passion for one particular theme park attraction would lead his family on a breathtaking journey of hope and discovery.How many rides does it take for an ending to become a new beginning?

    As a teenager he'd received letters from this stranger father, a self-proclaimed poet and con man doing time in federal prison for bank robbery. Another Bullshit Night in Suck City tells the story of the trajectory that led Nick and his father onto the streets, into that shelter, and finally to each other. .

    Professors are asked to consider their demise and to ruminate on what matters most to them: What wisdom would we impart to the world if we knew it was our last chance? If we had to vanish tomorrow, what would we want as our legacy?When Randy Pausch, a computer science professor at Carnegie Mellon, was asked to give such a lecture, he didn't have to imagine it as his last, since he had recently been diagnosed with terminal cancer. But the lecture he gave, 'Really Achieving Your Childhood Dreams', wasn't about dying. It was about the importance of overcoming obstacles, of enabling the dreams of others, of seizing every moment (because time is all you have and you may find one day that you have less than you think). It was a summation of everything Randy had come to believe. It was about living.In this book, Randy Pausch has combined the humour, inspiration, and intelligence that made his lecture such a phenomenon and given it an indelible form. It is a book that will be shared for generations to come.

    Nestled in the Smoky Mountains of eastern Tennessee, the town of Johnson City had always seemed exempt from the anxieties of modern American life. But when the local hospital treated its first AIDS patient, a crisis that had once seemed an urban problem had arrived in the town to stay. Working in Johnson City was Abraham Verghese, a young Indian doctor specializing in infectious diseases. Dr. Verghese became by necessity the local AIDS expert, soon besieged by a shocking number of male and female patients whose stories came to occupy his mind, and even take over his life. Verghese brought a singular perspective to Johnson City: as a doctor unique in his abilities; as an outsider who could talk to people suspicious of local practitioners; above all, as a writer of grace and compassion who saw that what was happening in this conservative community was both a medical and a spiritual emergency."