But molecules, such as water and sugar, are not alive. So how do our cells--assemblies of otherwise "dead" molecules--come to life, and together constitute a living being? In "Life's Ratchet," physicist Peter M. Hoffmann locates the answer to this age-old question at the nanoscale. The complex molecules of our cells can rightfully be called "molecular machines," or "nanobots"; these machines, unlike any other, work autonomously to create order out of chaos. Tiny electrical motors turn electrical voltage into motion, tiny factories custom-build other molecular machines, and mechanical machines twist, untwist, separate and package strands of DNA. The cell is like a city--an unfathomable, complex collection of molecular worker bees working together to create something greater than themselves. Life, Hoffman argues, emerges from the random motions of atoms filtered through the sophisticated structures of our evolved machinery. We are essentially giant assemblies of interacting nanoscale machines; machines more amazing than can be found in any science fiction novel. Incredibly, the molecular machines in our cells function without a mysterious "life force," nor do they violate any natural laws. Scientists can now prove that life is not supernatural, and that it can be fully understood in the context of science. Part history, part cutting-edge science, part philosophy, "Life's Ratchet" takes us from ancient Greece to the laboratories of modern nanotechnology to tell the story of our quest for the machinery of life.

    “A riveting tale of derring-do” (Nature), this book reads like James Gleick’s Chaos combined with an Indiana Jones adventure.When leading Princeton physicist Paul Steinhardt began working in the 1980s, scientists thought they knew all the conceivable forms of matter. The Second Kind of Impossible is the story of Steinhardt’s thirty-five-year-long quest to challenge conventional wisdom. It begins with a curious geometric pattern that inspires two theoretical physicists to propose a radically new type of matter—one that raises the possibility of new materials with never before seen properties, but that violates laws set in stone for centuries. Steinhardt dubs this new form of matter “quasicrystal.” The rest of the scientific community calls it simply impossible. The Second Kind of Impossible captures Steinhardt’s scientific odyssey as it unfolds over decades, first to prove viability, and then to pursue his wildest conjecture—that nature made quasicrystals long before humans discovered them. Along the way, his team encounters clandestine collectors, corrupt scientists, secret diaries, international smugglers, and KGB agents. Their quest culminates in a daring expedition to a distant corner of the Earth, in pursuit of tiny fragments of a meteorite forged at the birth of the solar system. Steinhardt’s discoveries chart a new direction in science. They not only change our ideas about patterns and matter, but also reveal new truths about the processes that shaped our solar system. The underlying science is important, simple, and beautiful—and Steinhardt’s firsthand account is “packed with discovery, disappointment, exhilaration, and persistence...This book is a front-row seat to history as it is made” (Nature).

    Based on her work at the Santa Fe Institute and drawing on its interdisciplinary strategies, Mitchell brings clarity to the workings of complexity across a broad range of biological, technological, and social phenomena, seeking out the general principles or laws that apply to all of them. Richly illustrated, Complexity: A Guided Tour--winner of the 2010 Phi Beta Kappa Book Award in Science--offers a wide-ranging overview of the ideas underlying complex systems science, the current research at the forefront of this field, and the prospects for its contribution to solving some of the most important scientific questions of our time.

    From Edward Lorenz’s discovery of the Butterfly Effect, to Mitchell Feigenbaum’s calculation of a universal constant, to Benoit Mandelbrot’s concept of fractals, which created a new geometry of nature, Gleick’s engaging narrative focuses on the key figures whose genius converged to chart an innovative direction for science. In Chaos, Gleick makes the story of chaos theory not only fascinating but also accessible to beginners, and opens our eyes to a surprising new view of the universe.

    Dennett, whom Chet Raymo of The Boston Globe calls "one of the most provocative thinkers on the planet," focuses his unerringly logical mind on the theory of natural selection, showing how Darwin's great idea transforms and illuminates our traditional view of humanity's place in the universe. Dennett vividly describes the theory itself and then extends Darwin's vision with impeccable arguments to their often surprising conclusions, challenging the views of some of the most famous scientists of our day.

    Finding this natural basis of life has proved elusive, but in the eloquent and creative Into the Cool, Eric D. Schneider and Dorion Sagan look for answers in a surprising place: the second law of thermodynamics. This second law refers to energy's inevitable tendency to change from being concentrated in one place to becoming spread out over time. In this scientific tour de force, Schneider and Sagan show how the second law is behind evolution, ecology,economics, and even life's origin.Working from the precept that "nature abhors a gradient," Into the Cool details how complex systems emerge, enlarge, and reproduce in a world tending toward disorder. From hurricanes here to life on other worlds, from human evolution to the systems humans have created, this pervasive pull toward equilibrium governs life at its molecular base and at its peak in the elaborate structures of living complex systems. Schneider and Sagan organize their argument in a highly accessible manner, moving from descriptions of the basic physics behind energy flow to the organization of complex systems to the role of energy in life to the final section, which applies their concept of energy flow to politics, economics, and even human health.A book that needs to be grappled with by all those who wonder at the organizing principles of existence, Into the Cool will appeal to both humanists and scientists. If Charles Darwin shook the world by showing the common ancestry of all life, so Into the Cool has a similar power to disturb—and delight—by showing the common roots in energy flow of all complex, organized, and naturally functioning systems.“Whether one is considering the difference between heat and cold or between inflated prices and market values, Schneider and Sagan argue, we can apply insights from thermodynamics and entropy to understand how systems tend toward equilibrium. The result is an impressive work that ranges across disciplinary boundaries and draws from disparate literatures without blinking.”—Publishers Weekly

    All of us can remember a moment as a child when time became a personal reality, when we realized what a "year" was, or asked ourselves when "now" happened. Common sense says time moves forward, never backward, from cradle to grave. Nevertheless, Einstein said that time is an illusion. Nature's laws, as he and Newton defined them, describe a timeless, deterministic universe within which we can make predictions with complete certainty. In effect, these great physicists contended that time is reversible and thus meaningless.

    The book was based on a course of public lectures delivered by Schrödinger in February 1943 at Trinity College, Dublin. Schrödinger's lecture focused on one important question: "how can the events in space and time which take place within the spatial boundary of a living organism be accounted for by physics and chemistry?" In the book, Schrödinger introduced the idea of an "aperiodic crystal" that contained genetic information in its configuration of covalent chemical bonds. In the 1950s, this idea stimulated enthusiasm for discovering the genetic molecule and would give both Francis Crick and James Watson initial inspiration in their research.

    Explaining why the whole is sometimes smarter than the sum of its parts, Johnson presents surprising examples of feedback, self-organization, and adaptive learning. How does a lively neighborhood evolve out of a disconnected group of shopkeepers, bartenders, and real estate developers? How does a media event take on a life of its own? How will new software programs create an intelligent World Wide Web? In the coming years, the power of self-organization -- coupled with the connective technology of the Internet -- will usher in a revolution every bit as significant as the introduction of electricity. Provocative and engaging, Emergence puts you on the front lines of this exciting upheaval in science and thought.

     Where are we? Who are we? Are our emotions, our beliefs, and our hopes and dreams ultimately meaningless out there in the void? Does human purpose and meaning fit into a scientific worldview?In short chapters filled with intriguing historical anecdotes, personal asides, and rigorous exposition, readers learn the difference between how the world works at the quantum level, the cosmic level, and the human level--and then how each connects to the other.  Carroll's presentation of the principles that have guided the scientific revolution from Darwin and Einstein to the origins of life, consciousness, and the universe is dazzlingly unique.Carroll shows how an avalanche of discoveries in the past few hundred years has changed our world and what really matters to us. Our lives are dwarfed like never before by the immensity of space and time, but they are redeemed by our capacity to comprehend it and give it meaning.The Big Picture is an unprecedented scientific worldview, a tour de force that will sit on shelves alongside the works of Stephen Hawking, Carl Sagan, Daniel Dennett, and E. O. Wilson for years to come.

    Refashioning the story of human evolution in a work that is certain to generate headlines, Wilson draws on his remarkable knowledge of biology and social behavior to show that group selection, not kin selection, is the primary driving force of human evolution. He proves that history makes no sense without prehistory, and prehistory makes no sense without biology. Demonstrating that the sources of morality, religion, and the creative arts are fundamentally biological in nature, Wilson presents us with the clearest explanation ever produced as to the origin of the human condition and why it resulted in our domination of the Earth’s biosphere.

    He believes that we should investigate what makes some countries more capable than others. Complex products—from films to robots, apps to automobiles—are a physical distillation of an economy’s knowledge, a measurable embodiment of its education, infrastructure, and capability. Economic wealth accrues when applications of this knowledge turn ideas into tangible products; the more complex its products, the more economic growth a country will experience.A radical new interpretation of global economics, Why Information Grows overturns traditional assumptions about the development of economies and the origins of wealth and takes a crucial step toward making economics less the dismal science and more the insightful one.

    Yet there’s a black hole at the heart of biology. We do not know why complex life is the way it is, or, for that matter, how life first began. In The Vital Question, award-winning author and biochemist Nick Lane radically reframes evolutionary history, putting forward a solution to conundrums that have puzzled generations of scientists.For two and a half billion years, from the very origins of life, single-celled organisms such as bacteria evolved without changing their basic form. Then, on just one occasion in four billion years, they made the jump to complexity. All complex life, from mushrooms to man, shares puzzling features, such as sex, which are unknown in bacteria. How and why did this radical transformation happen?The answer, Lane argues, lies in energy: all life on Earth lives off a voltage with the strength of a lightning bolt. Building on the pillars of evolutionary theory, Lane’s hypothesis draws on cutting-edge research into the link between energy and cell biology, in order to deliver a compelling account of evolution from the very origins of life to the emergence of multicellular organisms, while offering deep insights into our own lives and deaths.Both rigorous and enchanting, The Vital Question provides a solution to life’s vital question: why are we as we are, and indeed, why are we here at all?

    Dr Carl Sagan takes us on a great reading adventure, offering his vivid and startling insights into the brains of humans & beasts, the origin of human intelligence, the function of our most haunting legends and their amazing links to recent discoveries.

    The term “complexity” can be misleading, however, because what makes West’s discoveries so beautiful is that he has found an underlying simplicity that unites the seemingly complex and diverse phenomena of living systems, including our bodies, our cities and our businesses. Fascinated by issues of aging and mortality, West applied the rigor of a physicist to the biological question of why we live as long as we do and no longer. The result was astonishing, and changed science, creating a new understanding of energy use and metabolism: West found that despite the riotous diversity in the sizes of mammals, they are all, to a large degree, scaled versions of each other. If you know the size of a mammal, you can use scaling laws to learn everything from how much food it eats per day, what its heart-rate is, how long it will take to mature, its lifespan, and so on. Furthermore, the efficiency of the mammal’s circulatory systems scales up precisely based on weight: if you compare a mouse, a human and an elephant on a logarithmic graph, you find with every doubling of average weight, a species gets 25% more efficient—and lives 25% longer. This speaks to everything from how long we can expect to live to how many hours of sleep we need. Fundamentally, he has proven, the issue has to do with the fractal geometry of the networks that supply energy and remove waste from the organism's body. West's work has been game-changing for biologists, but then he made the even bolder move of exploring his work's applicability to cities. Cities, too, are constellations of networks and laws of scalability relate with eerie precision to them. For every doubling in a city's size, the city needs 15% less road, electrical wire, and gas stations to support the same population. More amazingly, for every doubling in size, cities produce 15% more patents and more wealth, as well as 15% more crime and disease. This broad pattern lays the groundwork for a new science of cities. Recently, West has applied his revolutionary work on cities and biological life to the business world. This investigation has led to powerful insights into why some companies thrive while others fail. The implications of these discoveries are far-reaching, and are just beginning to be explored. Scale is a thrilling scientific adventure story about the elemental natural laws that bind us together in simple but profound ways. Through the brilliant mind of Geoffrey West, we can envision how cities, companies and biological life alike are dancing to the same simple, powerful tune, however diverse and unrelated they are to each other.From the Hardcover edition.