of Speculation is a portrait of a marriage. It is also a beguiling rumination on the mysteries of intimacy, trust, faith, knowledge, and the condition of universal shipwreck that unites us all. Jenny Offill's heroine, referred to in these pages as simply "the wife," once exchanged love letters with her husband postmarked Dept. of Speculation, their code name for all the uncertainty that inheres in life and in the strangely fluid confines of a long relationship. As they confront an array of common catastrophes - a colicky baby, a faltering marriage, stalled ambitions - the wife analyzes her predicament, invoking everything from Keats and Kafka to the thought experiments of the Stoics to the lessons of doomed Russian cosmonauts. She muses on the consuming, capacious experience of maternal love, and the near total destruction of the self that ensues from it as she confronts the friction between domestic life and the seductions and demands of art. With cool precision, in language that shimmers with rage and wit and fierce longing, Jenny Offill has crafted an exquisitely suspenseful love story that has the velocity of a train hurtling through the night at top speed. Exceptionally lean and compact, Dept. of Speculation is a novel to be devoured in a single sitting, though its bracing emotional insights and piercing meditations on despair and love will linger long after the last page.

    Exasperated that his wife, Glynis, has concocted endless excuses why it's never the right time to go, Shep finally announces he's leaving for a Tanzanian island, with or without her. Yet Glynis has some news of her own: she's deathly ill. Shep numbly puts his dream aside, while his nest egg is steadily devastated by staggering bills that their health insurance only partially covers. Astonishingly, illness not only strains their marriage but saves it.From acclaimed New York Times bestselling author Lionel Shriver comes a searing, ruthlessly honest novel. Brimming with unexpected tenderness and dry humor, it presses the question: How much is one life worth?

    In this short book, he provides readers with a fictional account of how a real, new medical technology could revolutionize the future of medicine by curing with sound. THE TUMOR follows the present day experience of the fictional patient Paul, an otherwise healthy 35-year-old father who is diagnosed with a malignant brain tumor. Grisham takes readers through a detailed account of Paul’s treatment and his family’s experience that doesn’t end as we would hope. Grisham then explores an alternate future, where Paul is diagnosed with the same brain tumor at the same age, but in the year 2025, when a treatment called focused ultrasound is able to extend his life expectancy. Focused ultrasound has the potential to treat not just brain tumors, but many other disorders, including Parkinson’s, Alzheimer’s, hypertension, and prostate, breast and pancreatic cancer. For more information, you can visit The Focused Ultrasound Foundation’s website. Here you will find a video of Grisham on the TEDx stage with the Foundation’s chairman and a Parkinson’s patient who brings the audience to its feet sharing her incredible story of a focused ultrasound “miracle.” Readers will get a taste of the narrative they expect from Grisham, but this short book will also educate and inspire people to be hopeful about the future of medical innovation.

    She moved in the most exclusive circles in Washington, D.C., rubbed elbows with big politicians, and worked on Capitol Hill. As far as she was concerned, she was changing the world. And then her mother had a heart attack. Carolyn came home to help her father with his rural medical practice in the Tennessee mountains. She'd fill in for a few days as the receptionist until her mother could return to work. Or so she thought. But days turned into weeks. Her job now included following hazmat regulations for cleaning up bodily fluids; maintaining composure when confronted with a splinter the size of a steak knife; distinguishing between a "pain," a "strain," and a "sprain" on indecipherable Medicare forms; and tending to the loquacious Miss Hiawatha, whose daily doctor visits were never billed.Eventually, Jourdan gave up her Mercedes and made do with a twenty-year-old postal jeep. She shed her suits for scrubs. And the funny thing was, she liked her new life. As she watched her father work tirelessly and uncomplainingly, she saw what making a difference really meant: being on call all hours of the day and night, tolerating the local drug addict's frequent phone calls, truly listening to Miss Hiawatha. It meant just showing up, every day, and taking care of every person in Strawberry Plains and beyond, whether he got paid to do it or not. And for his daughter, it meant learning that her real place to change the world was right here—in her hometown—by her father's side.

    Six months later, she appears in a photograph in a gossip magazine exiting the Tropicana Club in Los Angeles on the arm of Olivia de Havilland.In this chain of six richly detailed and atmospheric stories, each told from a different perspective, Towles unfolds the events that take Eve to the heart of Old Hollywood. Beginning in the dining car of the Golden State Limited in September 1938, we follow Eve to the elegant rooms of the Beverly Hills Hotel, the fabled tables of Antonio’s, the amusement parks on the Santa Monica piers, the afro-Cuban dance clubs of Central Avenue, and ultimately the set of Gone with The Wind.With the glamour and grit of the studio system’s golden age as a backdrop, Towles introduces in each story a memorable new character whose fate may well be altered by their encounter with Eve. In following the thread of these varied encounters, we watch as Eve forges a new and unexpected life for herself in late 1930s Los Angeles.

    In "Near-Extinct Birds of the Central Cordillera," an ornithologist being held hostage in the Colombian rain forest finds that he respects his captors for their commitment to a cause, until he realizes that the Revolution looks a lot like big business. In "The Good Ones Are Already Taken," the wife of a Special Forces officer battles a Haitian voodoo goddess with whom her husband is carrying on a not-entirely-spiritual relationship. And in "The Lion's Mouth," a disillusioned aid worker makes a Faustian bargain to become a diamond smuggler for the greater good. With masterful pacing and a robust sense of the absurd, each story in Brief Encounters with Che Guevara is a self-contained adventure, steeped in the heady mix of tragedy and danger, excitement and hope, that characterizes countries in transition.

    It features the story 'Ichthyology', where a young boy watches his father spiral from divorce to suicide.

    Although her body healed rapidly, her memories never returned. Yet after just three weeks in the hospital, Su was released and once again charged with the care of two toddlers and a busy household. Adrift in a world about which she understood almost nothing, Su became an adept mimic, gradually creating routines and rituals that sheltered her and her family, however narrowly, from the near-daily threat of disaster, or so she thought. Though Su would eventually relearn to tie her shoes, cook a meal, and read and write, nearly twenty years would pass before a series of personally devastating events shattered the normal life she had worked so hard to build, and she realized that she would have to grow up all over again.In her own indelible voice, Su offers us a view from the inside of a terrible injury, with the hope that her story will help give other brain injury sufferers and their families the resolve and courage to build their lives anew. Piercing, heartbreaking, but finally uplifting, this book is the true story of a woman determined to live life on her own terms.

    This is a world of lost fathers and redemptive con men, of meth tweakers on desperate odysseys and men committing suicide by fishing.In "Thief," an aluminum worker turns unlikely detective to solve the mystery of which of his kids is stealing from the family vacation fund. In "We Live in Water," a lawyer returns to a corrupt North Idaho town to find the father who disappeared thirty years earlier. In "Anything Helps," a homeless man has to "go to cardboard" to raise enough money to buy his son the new Harry Potter book. In "Virgo," a local newspaper editor tries to get back at his superstitious ex-girlfriend by screwing with her horoscope. Also included are the stories "Don't Eat Cat" and "Statistical Abstract of My Hometown, Spokane, Washington," both of which achieved a cult following after publication online.

    Jacobs tackles his most challenging experiment yet: a yearlong mission to radically improve every element of his body and mind—from his brain to his fingertips to his abs.From the bestselling author of The Year of Living Biblically and The Know-It-All comes the true and truly hilarious story of one person’s quest to become the healthiest man in the world. Hospitalized with a freak case of tropical pneumonia, goaded by his wife telling him, “I don’t want to be a widow at forty-five,” and ashamed of a middle-aged body best described as “a python that swallowed a goat,” A.J. Jacobs felt compelled to change his ways and get healthy. And he didn’t want only to lose weight, or finish a triathlon, or lower his cholesterol. His ambitions were far greater: maximal health from head to toe. The task was epic. He consulted an army of experts— sleep consultants and sex clinicians, nutritionists and dermatologists. He subjected himself to dozens of different workouts—from Strollercize classes to Finger Fitness sessions, from bouldering with cavemen to a treadmill desk. And he took in a cartload of diets: raw foods, veganism, high protein, calorie restriction, extreme chewing, and dozens more. He bought gadgets and helmets, earphones and juicers. He poked and he pinched. He counted and he measured. The story of his transformation is not only brilliantly entertaining, but it just may be the healthiest book ever written. It will make you laugh until your sides split and endorphins flood your bloodstream. It will alter the contours of your brain, imprinting you with better habits of hygiene and diet. It will move you emotionally and get you moving physically in surprising ways. And it will give you occasion to reflect on the body’s many mysteries and the ultimate pursuit of health: a well-lived life.

    Yet despite advanced training in cancer genetics and years of practicing medicine, Dr. Theo Ross was never certain whether the history of cancers in her family was simple bad luck or a sign that they were carriers of a cancer-causing genetic mutation. Then she was diagnosed with melanoma, and for someone with a dark complexion, melanoma made no sense. It turned out there was a genetic factor at work.   Using her own family’s story, the latest science of cancer genetics, and her experience as a practicing physician, Ross shows readers how to spot the patterns of inherited cancer, how to get tested for cancer-causing genes, and what to do if you have one. With a foreword by Siddartha Mukherjee, prize winning author of The Emperor of All Maladies, this will be the first authoritative, go-to for people facing inherited cancer, this book empowers readers to face their genetic heritage without fear and to make decisions that will keep them and their families healthy.

    The top specialists in the world were powerless to help, and scientific research on her disease was at a near standstill. She was running out of money. And she was all alone, with no one to care for her.Having exhausted the plausible ideas, Rehmeyer turned to an implausible one. She followed the advice of strangers she'd met on the Internet. They struck her as crazy but they had recovered from chronic fatigue syndrome as severe as hers. Leaving behind everything she owned, she drove into the desert, testing the theory that mold in her home and belongings was making her sick. Stripped of the life she'd known and the future she'd imagined, Rehmeyer felt as though she were going to the desert to die.But she didn't die. She used her scientific savvy and investigative journalism skills to find a path to wellness and uncovered how shocking scientific neglect and misconduct had forced her, and millions of others, to go it alone. In stunning prose, Rehmeyer describes how her illness transformed her understanding of science, medicine, and spirituality. Through the Shadowlands will bring scientific authority to a misunderstood disease while telling an incredible and compelling story of tenacity, resourcefulness, acceptance, and love.

    A young man is just a college freshman when he meets Emily. They share a passion for Edward Albee and ecstasy and fall hard and fast in love. But soon Emily has to move home to Elba, New York, and he flunks out of school and joins the army. Desperate to keep their relationship alive, they marry before he ships out to Iraq. But as an army medic, he is unprepared for the grisly reality that awaits him. His fellow soldiers smoke; they huff computer duster; they take painkillers; they watch porn. And many of them die. He and Emily try to make their long-distance marriage work, but when he returns from Iraq, his PTSD is profound, and the drugs on the street have changed. The opioid crisis is beginning to swallow up the Midwest. Soon he is hooked on heroin, and so is Emily. They attempt a normal life, but with their money drying up, he turns to the one thing he thinks he could be really good at – robbing banks.Hammered out on a prison typewriter, Cherry marks the arrival of a raw, bleakly hilarious, and surprisingly poignant voice straight from the dark heart of America.

    In only a few decades, the medical system has been overrun by organizations seeking to exploit for profit the trust that vulnerable and sick Americans place in their healthcare. Our politicians have proven themselves either unwilling or incapable of reining in the increasingly outrageous costs faced by patients, and market-based solutions only seem to funnel larger and larger sums of our money into the hands of corporations. Impossibly high insurance premiums and inexplicably large bills have become facts of life; fatalism has set in. Very quickly Americans have been made to accept paying more for less. How did things get so bad so fast?Breaking down this monolithic business into the individual industries--the hospitals, doctors, insurance companies, and drug manufacturers--that together constitute our healthcare system, Rosenthal exposes the recent evolution of American medicine as never before. How did healthcare, the caring endeavor, become healthcare, the highly profitable industry? Hospital systems, which are managed by business executives, behave like predatory lenders, hounding patients and seizing their homes. Research charities are in bed with big pharmaceutical companies, which surreptitiously profit from the donations made by working people. Patients receive bills in code, from entrepreneurial doctors they never even saw.The system is in tatters, but we can fight back. Dr. Elisabeth Rosenthal doesn't just explain the symptoms, she diagnoses and treats the disease itself. In clear and practical terms, she spells out exactly how to decode medical doublespeak, avoid the pitfalls of the pharmaceuticals racket, and get the care you and your family deserve. She takes you inside the doctor-patient relationship and to hospital C-suites, explaining step-by-step the workings of a system badly lacking transparency. This is about what we can do, as individual patients, both to navigate the maze that is American healthcare and also to demand far-reaching reform. An American Sickness is the frontline defense against a healthcare system that no longer has our well-being at heart.

    "Filled with warmth and humor, sadness and tenderness, songs and poems, Lake Wobegon Days is an unforgettable portrait of small-town American life, of why 'we are what we are' and why 'smart doesn't count for much."