We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

    The text's major theme "Changes, Choices, and Constraints" explores: Contemporary "changes "in families and their structure Impacts on the "choices "that are available to family members ""Constraints ""that often limit our choices Through this approach, students are better able to understand what the research and statistics mean "for themselves"! Marriages and Families balances theoretical and empirical discussions with practical examples and applications. It highlights important contemporary changes in society and the family. This text is written from a sociological perspective and incorporates material from other disciplines: history, economics, social work, psychology, law, biology, medicine, family studies, women's studies, and anthropology. "More about the themes: " "Changes"Examines how recent profound structural and attitudinal changes affect family forms, interpersonal relationships, and raising children. It reaches beyond the traditional discussions to explore racial-ethnic families, single-parent families and gay families as well as the recent scholarship by and about men, fathers, and grandfathers. Contemporary American marriages and families vary greatly in structure, dynamics, and cultural heritage. Thus, discussions of gender roles, social class, race, ethnicity, age, and sexual orientation are integrated throughout this book. To further strengthen students understanding of the growing diversity among today's families, the author included a series of boxes that focus on families from many cultures. "Choices"On the individual level, family members have many more choices today than ever before. People feel freer to postpone marriage, to cohabit, or to raise children as single parents. As a result, household forms vary greatly, ranging from commuter marriages to those in which several generations live together under the same roof. "Constraints"Although family members choices are more varied today, we also face greater macro- level constraints. Our options are increasingly limited, for example, by government policies. Economic changes often shape family life and not vice versa. Political and legal institutions also have a major impact on most families in tax laws, welfare reform, and even in defining what a family is. Because laws, public policies, and religious groups affect our everyday lives, the author has framed many discussions of individual choices within the larger picture of the institutional constraints that limit our choices.To learn more about the new edition, click here to visit the showcase site.

    Now they're looking for help. Ron Deal, who has counseled single parents and remarried couples for many years, helps single parents--as well as those who date them--navigate the potential pitfalls involved. He gives perspective on when a relationship may be harmful to the children as well as how it can be a blessing to all. Always at the forefront is the goal of strengthening families. Includes questions for individual or group study.

    Now, with even more illustrations, it encompasses all of the principles of therapeutic exercise and manual therapy. This renowned manual remains the authoritative source for exercise instruction for the therapist and for patient self management.

    The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    Whether you work in emergency medicine, or just want to be prepared, this book will be your essential guide.Following the latest clinical guidelines and evidence, written and reviewed by experts, this handbook will ensure you are up-to-date and have the confidence to deal with all emergency presentations, practices, and procedures. Following the latest developments in the field, such as infection control, DNR orders, advanced directives and learning disability. The book also includes new sections specifically outlining patient advice and information, as well as new and revised vital information on paediatrics and psychiatry. For all junior doctors, specialist nurses, paramedics, clinical students, GPs and other allied health professionals, this rapid-reference handbook will become a vital companion for both study and practice.

    Dr. Ray Long guides you on a visual narrative through the anatomy, biomechanics, and physiology of this ancient art, decoding each pose along the way. The Mat Companion series provides you with beautifully illustrated, step-by-step instructions on how to use scientific principles to obtain the maximum benefit from your practice. Each book includes the Bandha Yoga Codex, a simple five-step process that can be applied to any pose to improve strength, flexibility, and precision -- no matter what style of yoga you practice.

     What is it like to be the senior surgeon when a young woman is brought to casualty with a life-threatening bleed? What does the fear of cancer do to a person? Is it ever best not to tell the patient everything? Tender is the Scalpel’s Edge draws on Gautam Das’s real-life experiences working in Britain’s busy NHS hospitals, from the plunging depths of a patient dying on the operating table to the euphoria of a life saved by teamwork and skill. Described in exquisite detail and with extreme sensitivity, Gautam shares his journey from a medical student fighting his own inner demons to a senior NHS consultant surgeon. Shards of his earlier life in India add to the richness of the narrative in tales that observe life with all its contradictions, like the little village boy with bone cancer. While other anecdotes take in the lighter side of life, Tender is the Scalpel’s Edge is written to inform and engross the general reader, as well as those with a curiosity of life behind the surgeon’s mask. Written in a manner similar to other medical biographies including Henry Marsh’s Do No Harm, Atul Gawande’s Being Mortal and When Breath Becomes Air by Paul Kalanithi, Tender is the Scalpel’s Edge is a moving collection of true stories from a professional at the frontline of medical care.

    Crank. Bennies. Dexies. Greenies. Black Beauties. Purple Hearts. Crystal. Ice. And, of course, Speed. Whatever their street names at the moment, amphetamines have been an insistent force in American life since they were marketed as the original antidepressants in the 1930s. On Speed tells the remarkable story of their rise, their fall, and their surprising resurgence. Along the way, it discusses the influence of pharmaceutical marketing on medicine, the evolving scientific understanding of how the human brain works, the role of drugs in maintaining the social order, and the centrality of pills in American life. Above all, however, this is a highly readable biography of a very popular drug. And it is a riveting story.Incorporating extensive new research, On Speed describes the ups and downs (fittingly, there are mostly ups) in the history of amphetamines, and their remarkable pervasiveness. For example, at the same time that amphetamines were becoming part of the diet of many GIs in World War II, an amphetamine-abusing counterculture began to flourish among civilians. In the 1950s, psychiatrists and family doctors alike prescribed amphetamines for a wide variety of ailments, from mental disorders to obesity to emotional distress. By the late 1960s, speed had become a fixture in everyday life: up to ten percent of Americans were thought to be using amphetamines at least occasionally.Although their use was regulated in the 1970s, it didn't take long for amphetamines to make a major comeback, with the discovery of Attention Deficit Disorder and the role that one drug in the amphetamine family--Ritalin--could play in treating it. Today's most popular diet-assistance drugs differ little from the diet pills of years gone by, still speed at their core. And some of our most popular recreational drugs--including the -mellow- drug, Ecstasy--are also amphetamines. Whether we want to admit it or not, writes Rasmussen, we're still a nation on speed.

    It is written to impart a sense of intellectual history of biochemistry, an understanding of the tools and approaches used to solve biochemical puzzles, and a hint of the excitement that accompanies new discoveries. This edition has been thoroughly updated to reflect the most recent advances in biochemistry, particularly in the areas of genomics and structural biology. A new chapter focuses on cytoskeletal and motor proteins, currently one of the most active areas of research in biochemistry.

    This book gives students all the tools they need to succeed on the new TOEFL integrated-skills test.

    Offering numerous examples and a step-by-step approach, it covers both the Assembly and C programming languages and devotes separate chapters to interfacing with peripherals such as Timers, LCD, Serial Ports, Interrupts, Motors and more. A unique chapter on hardware design of the PIC system and the PIC trainer round out coverage. Systematic coverage of the PIC18 family of Microcontrollers. Assembly language and C language programming and interfacing techniques. Thorough coverage of Architectures and Assembly language programming of the PIC18. Thorough coverage of C language programming of the PIC18. Separate chapters on programming and interfacing the PIC with peripherals - Includes information on how to interface the PIC with LCD, keyboard, ADC, DAC, Sensors, Serial Ports, Timers, DC and Stepper Motors, Optoisolators, and RTC. Covers how to program each peripheral, first using the Assembly language and then using the C language. Those involved with PIC programming and interfacing using Assembly and C languages."

    The new edition from Chopra includes many topics encompassing the theory of structural dynamics and the application of this theory regarding earthquake analysis, response, and design of structures. No prior knowledge of structural dynamics is assumed and the manner of presentation is sufficiently detailed and integrated, to make the book suitable for self-study by students and professional engineers.

    In chapters that follow, detailed topic reviews cover polynomial, trigonometric, exponential, logarithmic, and rational functions; coordinate and three-dimensional geometry; numbers and operations; data analysis, statistics, and probability; and graphing calculators, their operations and applications. Six full-length model tests with answers, explanations, and self-evaluation charts conclude this manual.

    The book offers insight into 21st century modern healthcare and the state of society. You will laugh, cry, and question your beliefs about the healthcare system and patients. Read this before you go to the doctor next and share this information with your family. Throughout the United States stories like these are unfolding each day as you witness the stress of physician training and the ups and downs of the physician's and patient's lives. Dr. Brandon Green is a pseudonym, or pen name, for author who wishes to remain anonymous. He is an Attending Surgeon at an inner-city Level 1 Trauma Center. The author's goals for writing this book include the following: 1.Create awareness and discussion about today’s healthcare and society. 2.Raise money with 30% of profits from the sale of this book being donated to healthcare non-profit organizations such as the American Cancer Society, the American Heart Association, and any current global medical pandemic funds. 3.Therapy for the author to recount the intern year, which was more stressful and educational than ever imagined. Unexpected emotions occurred and life lessons were taught beyond the surgical training. The short stories are real occurrences that happened to the author and his other two co-interns in one residency year. The author broke ties with the publisher who wanted to adjust the stories to meet societal norms, and now the work is being self published with profits as above going to charity instead of a large publishing company. The names and locations have been changed to provide privacy protection and follow HIPPA guidelines. The author hopes to continue dialogue and discussion on stories from behind the scenes at hospitals, clinics, and in the operating rooms. It's beneficial to communicate with colleagues and other healthcare professionals and staff running into similar circumstances on a day to day basis. Please visit DIARYOFAHO.COM and email your stories to be published on the website and social media.This is a work of sociology, psychology, medicine, surgery, dealing with the public, putting others ins front of yourself, and self-reflective learning. Any story will be accepted and uploaded into the blog and social media. Stories will be screened for HIPPA compliance prior to publishing online. Thank you for taking the time to read and understand what’s happening in modern healthcare training.