This cycle is at the root of all addictions, addictions to drugs, sex, love, cigarettes, soap operas, wealth, and wisdom itself. But why should this be so? Why are we desperate for what we don't have, or can't have, often at great cost to what we do have, thereby risking our peace and contentment, our safety, and even our lives?"The answer, says Dr. Marc Lewis, lies in the structure and function of the human brain. Marc Lewis is a distinguished neuroscientist. And, for many years, he was a drug addict himself, dependent on a series of dangerous substances, from LSD to heroin. His narrative moves back and forth between the often dark, compellingly recounted story of his relationship with drugs and a revelatory analysis of what was going on in his brain. He shows how drugs speak to the brain - which is designed to seek rewards and soothe pain - in its own language. He shows in detail the neural mechanics of a variety of powerful drugs and of the onset of addiction, itself a distortion of normal perception.Dr. Lewis freed himself from addiction and ended up studying it. At the age of 30 he traded in his pharmaceutical supplies for the life of a graduate student, eventually becoming a professor of developmental psychology, and then of neuroscience - his field for the last 12 years. This is the story of his journey, seen from the inside out.

    For all his expertise, he admits he’s still terrified that “someone will keep something from me, and when they tell me the truth, I’ll be useless.”Treating other physicians has become one of Shapiro’s specialties. When the obstetrician Amelia Sorvino seeks his help—distraught that her own medical error could have injured a patient’s baby— Shapiro finds his talents as counselor and healer pushed to their limits. Session by session, he works to discover the sources of Amelia’s anguish--for his own sake as much as hers: he’s familiar with the burden of a doctor’s guilt, and he has seen how loss and trauma, if unchecked, can echo from generation to generation in a family. In this probing, intensely personal memoir, the words “Physician, heal thyself” assume a fresh and moving urgency.

    We take for granted that we can remember, feel emotion, navigate, empathize, and understand the world around us, but how would our lives change if these abilities were dramatically enhanced--or disappeared overnight?Helen Thomson has spent years traveling the world, tracking down incredibly rare brain disorders. In Unthinkable she tells the stories of nine extraordinary people she encountered along the way. From the man who thinks he's a tiger to the doctor who feels the pain of others just by looking at them to a woman who hears music that’s not there, their experiences illustrate how the brain can shape our lives in unexpected and, in some cases, brilliant and alarming ways.Story by remarkable story, Unthinkable takes us on an unforgettable journey through the human brain. Discover how to forge memories that never disappear, how to grow an alien limb, and how to make better decisions. Learn how to hallucinate and how to make yourself happier in a split second. Find out how to avoid getting lost, how to see more of your reality, even how exactly you can confirm you are alive. Think the unthinkable.

    Mixing memoir with mendacity, Slater examines memories of her youth, when after being diagnosed with a strange illness she developed seizures and neurological disturbances—and the compulsion to lie. Openly questioning the reliability of memoir itself, Slater presents the mesmerizing story of a young woman who discovers not only what plagues her but also what cures her—the birth of her sensuality, her creativity as an artist, and storytelling as an act of healing.

    At age thirteen, he is mentally and developmentally between one and three years old and will need constant care for the rest of his life. Brown travels the globe, meeting with genetic scientists and neurologists as well as parents, to solve the questions Walker’s doctors can’t answer. In his journey, he offers an insightful critique of society’s assumptions about the disabled, and he discovers a connected community of families living with this illness. As Brown gradually lets go of his self-blame and hope for a cure, he learns to accept the Walker he loves, just as he is. Honest, intelligent, and deeply moving, The Boy in the Moon explores the value of a single human life.

    Trump and the toxic family that made him, Mary L. Trump, a trained clinical psychologist and Donald’s only niece, shines a bright light on the dark history of their family in order to explain how her uncle became the man who now threatens the world’s health, economic security, and social fabric.Mary Trump spent much of her childhood in her grandparents’ large, imposing house in the heart of Queens, where Donald and his four siblings grew up. She describes a nightmare of traumas, destructive relationships, and a tragic combination of neglect and abuse. She explains how specific events and general family patterns created the damaged man who currently occupies the Oval Office, including the strange and harmful relationship between Fred Trump and his two oldest sons, Fred Jr. and Donald.A first-hand witness to countless holiday meals and family interactions, Mary brings an incisive wit and unexpected humor to sometimes grim, often confounding family events. She recounts in unsparing detail everything from her uncle Donald’s place in the family spotlight and Ivana’s penchant for re-gifting to her grandmother’s frequent injuries and illnesses and the appalling way Donald, Fred Trump’s favorite son, dismissed and derided him when he began to succumb to Alzheimer’s.Numerous pundits, armchair psychologists, and journalists have sought to parse Donald J. Trump’s lethal flaws. Mary L. Trump has the education, insight, and intimate familiarity needed to reveal what makes Donald, and the rest of her clan, tick. She alone can recount this fascinating, unnerving saga, not just because of her insider’s perspective but also because she is the only Trump willing to tell the truth about one of the world’s most powerful and dysfunctional families.

    She has been estranged from her parents for many years (the reasons for which become quickly clear) and is horrified by what she discovers on her arrival.For years her mother has suffered from an undiagnosed mental illness but carefully hidden her delusions and unpredictable behaviour behind a carefully guarded mask, and has successfully isolated herself and her husband from all their friends. But once in hospital her mask begins to crack and her actions leave everyone baffled and confused ... and eventually scared for their lives.Meanwhile Vicki's father, who has been systematically starved and harruanged for years, and kept virtually a prisoner in his own home, begins to realise what has happened to him and embarks upon plans of his own to combat his wife.The ensuing power play between the two takes a dramatic turn and leaves Vicki stuck in the middle of a bizarre and ludicrously strange family dilemma. All this makes for an intensely gripping, yet black-humoured family drama which will leave you on the edge of your seat.

    She is seven; he is fifty-one. When Peter invites her and her mother to his house, the little girl finds a child's paradise of exotic pets and an elaborate backyard garden. Her mother, beset by mental illness and overwhelmed by caring for Margaux, is grateful for the attention Peter lavishes on her, and he creates an imaginative universe for her, much as Lewis Carroll did for his real-life Alice. In time, he insidiously takes on the role of Margaux's playmate, father, and lover. Charming and manipulative, Peter burrows into every aspect of Margaux's life and transforms her from a child fizzing with imagination and affection into a brainwashed young woman on the verge of suicide. But when she is twenty-two, it is Peter -- ill, and wracked with guilt -- who kills himself, at the age of sixty-six. Told with lyricism, depth, and mesmerizing clarity, Tiger, Tiger vividly illustrates the healing power of memory and disclosure. This extraordinary memoir is an unprecedented glimpse into the psyche of a young girl in free fall and conveys to readers -- including parents and survivors of abuse -- just how completely a pedophile enchants his victim and binds her to him.

    But he was alive and trapped inside his own body for ten years.In January 1988 Martin Pistorius, aged twelve, fell inexplicably sick. First he lost his voice and stopped eating. Then he slept constantly and shunned human contact. Doctors were mystified. Within eighteen months he was mute and wheelchair-bound. Martin's parents were told an unknown degenerative disease left him with the mind of a baby and less than two years to live.Martin was moved to care centers for severely disabled children. The stress and heartache shook his parents’ marriage and their family to the core. Their boy was gone. Or so they thought.Ghost Boy is the heart-wrenching story of one boy’s return to life through the power of love and faith. In these pages, readers see a parent’s resilience, the consequences of misdiagnosis, abuse at the hands of cruel caretakers, and the unthinkable duration of Martin’s mental alertness betrayed by his lifeless body.We also see a life reclaimed—a business created, a new love kindled—all from a wheelchair. Martin's emergence from his own darkness invites us to celebrate our own lives and fight for a better life for others.

    David Kushner grew up in the suburbs of Florida in the early 1970s, running wild with his friends, exploring, riding bikes, and disappearing into the nearby woods for hours at a time. One morning in 1973, however, everything changed. David's older brother Jon, making a trip to the local convenience store, vanished. This is the story of Jon's murder at the hands of two sadistic drifters and everything that happened after. "Alligator Candy "isn't only the chronicle of Jon's death, it is also the story of how parenting in America changed, casting light on the transition between two generations of children one raised on freedom, the other on fear. Jon's death was one of the first in what turned out to be a rash of child abductions and murders that dominated headlines for much of the 1970s and 80s. It was around this time that milk cartons began to feature the images of missing children, and newscasters began asking, It's 10:00, do you know where you children are? When one of Jon's killers received a parole hearing, David revisited the case that had so haunted him. Marshalling his skills as a journalist, he compiled all the details that he was sheltered from as a child, interviewing neighbors, reporters, cops, and his own family, and combing through yellowed news clippings. Haunting and intimate, "Alligator Candy" is a moving, disturbing, insightful, and inspiring meditation on grief, growth, family, and survival."

    They are promises. They are the only way to walk from one night to the other."Nina Riggs was just thirty-seven years old when initially diagnosed with breast cancer--one small spot. Within a year, the mother of two sons, ages seven and nine, and married sixteen years to her best friend, received the devastating news that her cancer was terminal.How does one live each day, "unattached to outcome"? How does one approach the moments, big and small, with both love and honesty?Exploring motherhood, marriage, friendship, and memory, even as she wrestles with the legacy of her great-great-great grandfather, Ralph Waldo Emerson, Nina Riggs's breathtaking memoir continues the urgent conversation that Paul Kalanithi began in his gorgeous When Breath Becomes Air. She asks, what makes a meaningful life when one has limited time?Brilliantly written, disarmingly funny, and deeply moving, The Bright Hour is about how to love all the days, even the bad ones, and it's about the way literature, especially Emerson, and Nina's other muse, Montaigne, can be a balm and a form of prayer. It's a book about looking death squarely in the face and saying "this is what will be."Especially poignant in these uncertain times, The Bright Hour urges us to live well and not lose sight of what makes us human: love, art, music, words.

    This is a heartbreakingly honest yet hopeful memoir reminiscent of Manic, Electroboy, and An Unquiet Mind.During the 1990s, three-time Olympian Suzy Favor Hamilton was the darling of American track and field. An outstanding runner, a major sports apparel spokesperson, and a happily married wife, she was the model for an active, healthy, and wholesome life. But her perfect facade masked a dark truth: manic depression and bipolar disorder that drove her obsession to perform and win. For years after leaving the track, Suzy wrestled with her condition, as well as the loss of a close friend, conflicted feelings about motherhood and her marriage, and lingering shame about her athletic career. After a misdiagnosis and a recommendation for medication that only exacerbated her mania and made her hypersexual, Suzy embarked on a new path, and assumed a new identity. Fueled by a newfound confidence, a feeling of strength and independence and a desire she couldn’t tamp down, she became a high-priced escort in Las Vegas, working as “Kelly.”But Suzy could not keep her double life a secret forever. When it was eventually exposed, it sent her into a reckless suicidal period where the only option seemed out. Finally, with the help of her devoted husband, Suzy finally got the proper medical help she needed. In this startling frank memoir, she recounts the journey to outrun her demons, revealing how a woman used to physically controlling her body learned to come to terms with her unstable mind. It is the story of a how a supreme competitor scored her most important victory of all—reclaiming her life from the ravages of an untreated mental illness. Today, thanks to diagnosis, therapy, Kelly has stepped into the shadows, but Suzy is building a better life, one day at a time. Sharing her story, Suzy is determined to raise awareness, provide understanding, and offer inspiration to others coping with their own challenges.

    Soon it was gone, only to be succeeded by another. And another. Strange, Karinthy thought, it had been years since Budapest had streetcars. Only then did he realize he was suffering from an auditory hallucination of extraordinary intensity. What in fact Karinthy was suffering from was a brain tumor, not cancerous but hardly benign, though it was only much later—after spells of giddiness, fainting fits, friends remarking that his handwriting had altered, and books going blank before his eyes—that he consulted a doctor and embarked on a series of examinations that would lead to brain surgery. Karinthy’s description of his descent into illness and his observations of his symptoms, thoughts, and feelings, as well as of his friends’ and doctors’ varied responses to his predicament, are exact and engrossing and entirely free of self-pity. A Journey Round My Skull is not only an extraordinary piece of medical testimony, but a powerful work of literature—one that dances brilliantly on the edge of extinction.

    . . ranges from the shocking to the simply lovely." —Marya Hornbacher Stacy Pershall grew up depressed and too smart for her own good, a deeply strange girl in Prairie Grove, Arkansas (population 1,000), where the prevailing wisdom was that Jesus healed all. From her days as a thirteen-year-old Jesus freak, through a battle with anorexia and bulimia, her first manic episode at eighteen, and the eventual diagnosis of bipolar disorder and borderline personality disorder, this spirited and at times mordantly funny memoir chronicles Pershall's journey through hell-several breakdowns and suicide attempts—and her struggle with the mental health care system. After her 2001 suicide attempt, broadcast live on a Webcam, Pershall realized the need to heal her mind and body. She found a revolutionary cure (Dialectical Behavioral Therapy) and a new mood-stabilizing medication. She also met a tattoo artist and discovered the healing power of body modification. By giving over her skin and enduring the physical pain, she learned about the true nature of trust.

    Born to survivalists in the mountains of Idaho, she prepared for the end of the world by stockpiling home-canned peaches and sleeping with her "head-for-the-hills bag". In the summer she stewed herbs for her mother, a midwife and healer, and in the winter she salvaged in her father's junkyard.Her father forbade hospitals, so Tara never saw a doctor or nurse. Gashes and concussions, even burns from explosions, were all treated at home with herbalism. The family was so isolated from mainstream society that there was no one to ensure the children received an education and no one to intervene when one of Tara's older brothers became violent.Then, lacking any formal education, Tara began to educate herself. She taught herself enough mathematics and grammar to be admitted to Brigham Young University, where she studied history, learning for the first time about important world events like the Holocaust and the civil rights movement. Her quest for knowledge transformed her, taking her over oceans and across continents, to Harvard and to Cambridge. Only then would she wonder if she'd traveled too far, if there was still a way home.Educated is an account of the struggle for self-invention. It is a tale of fierce family loyalty and of the grief that comes with severing the closest of ties. With the acute insight that distinguishes all great writers, Westover has crafted a universal coming-of-age story that gets to the heart of what an education is and what it offers: the perspective to see one's life through new eyes and the will to change it.