Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.

    By 1988 she was living at home but was brain dead after a tragic cycle of misunderstanding, over-medication, and culture clash: "What the doctors viewed as clinical efficiency the Hmong viewed as frosty arrogance." The Spirit Catches You and You Fall Down is a tragedy of Shakespearean dimensions, written with the deepest of human feeling. Sherwin Nuland said of the account, "There are no villains in Fadiman's tale, just as there are no heroes. People are presented as she saw them, in their humility and their frailty—and their nobility.

    

    The illustrations provide some of the best quality and most varied examples of skin conditions important to any health care pforessional dealing with skin problems.

    Blending Eastern and Western medical philosophy, Chopra puts together a clear and easy path to follow for perfect physical and emotional health. With influences from Ayurveda, the 6,000-year-old tradition of medicine from India, Chopra uses Western terminology to explain how we can reassess health and disease and shows how, by focusing on self-awareness, compassion and the mind, we can improve our physical well being. In this book, he also introduces the benefits of meditation and creative visualization.

    In The Tao of Poker, prize-winning poker player Larry Phillips offers more than 280 rules to bring you to new levels of personal achievement, just when and where you need them most.Here are some of The Tao of Poker’s rules for success:Take the long viewOnce you commit to a hand, play it strongDon’t throw in good money after badIf you think you’re beat, get outTry out these rules and watch your game, and your life, improve. Now you can be a winner at home, at work, and at the casino - wherever the stakes for success are high!

     Spot inconsistencies and lies, and apply logic to your daily life. If you want to become a critical, effective, and rational thinker instead of an irrational and snap-judging one, this book is for you. Critical thinking skills strengthen your decision making muscle, speed up your analysis and judgment, and help you spot errors easily. The Critical Mind offers a thorough introduction to the rules and principles of critical thinking. You will find widely usable and situation-specific advice on how to critically approach your daily life, business, friendships, opinions, and even social media. Critical thinking not only saves you time but saves you money and helps you prevent misunderstanding and disappointment. • Learn the main elements of critical thinking. • The theories and practices of the best critical thinkers of the world. • Tips to keep your brain in good shape and receptive to analysis. • Solve your problems with critical thinking. • Become a quicker and better decision maker. Cut out the inefficiencies of your life. The Critical Mind is a guideline for everyone who wishes to learn the basics of critical thinking. If you work in business, education, healthcare, or you study, you’ll find the book equally useful. The book takes a deep look at the framework of geniuses like Richard Paul and Linda Elder to give you a well-established foundation on effective thought. • Become a more effective communicator having relevant argument points. • How to apply critical thinking in a group. • Guiding questions that help you think more critically. • Four types of critical thinking exercise to deepen your knowledge each day. The Critical Mind gives you the best theories and practices to become a more successful and better thinker. Know that the people whom you admire for their mind aren’t aliens, they just use their minds differently. In this book, I unveil how and what they do differently. Delete this. Too repetitive. Put something about the author Discover hidden opportunities, gain a solution-oriented mindset, solve difficult tasks, and understand the world more deeply. Critical thinking will enhance your creativity, logic, intelligence, and helps you navigate through everyday life matters more easily. Think faster, argue better, and succeed consistently.

    He uses real-world examples to illustrate how modern advertising overemphasizes art and entertainment and neglects the most important rule of advertising-sell the product. With a keen eye and a no-holds-barred approach, Zyman discusses how advertising died, what killed it, and how to revive it. He addresses the most critical issues affecting any organization's sales and marketing departments, using his time-tested, unorthodox, and sometimes even counterintuitive principles in order to translate key strategies into positive business results. For marketing managers, advertisers, and CEOs, this book offers groundbreaking advice from one of the legends of modern marketing, as well as the knowledge, insights, tools, and direction to transform advertising strategies from hoping to planning, from art to science, from guessing to knowing, and from random success to planned success.

    They are the powerhouses of our cells, essential for the production and management of energy at cell level. Dr Sarah Myhill, together with Dr John McLaren Howard of Acumen Laboratories and Dr Norman Booth of Mansfield College Oxford, has spent many years studying the relationship between their malfunction and the commonest problem seen by GPs in the UK – fatigue. Their research findings have been published in three scientific papers in the International Journal of Clinical and Experimental Medicine, in 2009, 2012 and 2013. These studies showed that poor functioning of the mitochondria is the central problem in CFS. Patients with the worst mitochondrial function had the worst fatigue and vice versa. This is solid scientific evidence that CFS is a problem with mitochondria and has allowed the objective measurement of fatigue for the first time. With the publication of the third study, which showed that mitochondrial function tests and symptoms improved in patients who took measures to address their mitochondrial problems, Dr Myhill was ready to write this book. Here she explains the importance of healthy mitochondria, how we can measure their functioning and what we can do to keep them healthy, or restore them to health if problems arise. CFS is all in our cells, not in our minds!

    On playing fields across America, lives are being derailed by seemingly innocuous jolts to the head. From the peewees to the pros, concussions are reaching epidemic proportions. This book brings that hidden epidemic and its consequences out of the shadows. As frightening as the numbers are—estimates of sports-related concussions range from 1.6 million to 3.8 million annually in the United States—they can’t begin to explain the profound impact of a hidden health problem that can strike any of us. It is becoming increasingly clear that concussions, like severe head traumas, can rob us of our memory, our mental abilities, our very sense of self. Because the damage caused by a concussion is rarely visible to the naked eye or even on a brain scan, no one knows how many millions might be living lives devastated by an invisible injury too often shrugged off as “just a bump on the head.” This book puts a human face on a huge public health crisis. Through narratives that chronicle the poignant experiences of real people struggling with this invisible and often unrecognized brain injury, Linda Carroll and David Rosner bring home its potentially devastating consequences. Among those you will meet are a high school football player whose college dreams were derailed by a series of undiagnosed concussions, a hard-driving soccer star whose own struggles with concussions pushed her to crusade for safety reform as a coach and soccer mom, and an economist who lost her career because of lingering concussion symptoms from a fender bender. The Concussion Crisis weaves these human dramas with compelling stories of scientists and doctors who are unraveling the mysteries of how an invisible injury can wreak such havoc. It takes readers into the top labs, where scientists are teasing out what goes wrong in the brain after a jolt to the head, and into the nation’s leading concussion clinic, where patients get cutting-edge management and treatment. Carroll and Rosner analyze the cultural factors that allowed this burgeoning epidemic to fester unseen and untreated. They chronicle the growing public awareness sparked by the premature retirements of superstars like NFL quarterbacks Troy Aikman and Steve Young. And they argue for an immediate change in a macho culture that minimizes the dangers inherent in repeated jolts to the head. The Concussion Crisis sounds an urgent wake-up call to parents, coaches, trainers, doctors, and the athletes themselves. The book will stand as the definitive exploration of this heretofore-silent health crisis. It should be required reading for every parent with a child playing sports—in fact, by everyone who has ever suffered a hard bump on the head.

    Famously bipartisan, he advised presidents and Congress on health reform and originated central features of the Affordable Care Act. In Priced Out, Reinhardt offers an engaging and enlightening account of today's U.S. health care system, explaining why it costs so much more and delivers so much less than the systems of every other advanced country, why this situation is morally indefensible, and how we might improve it.The problem, Reinhardt says, is not one of economics but of social ethics. There is no American political consensus on a fundamental question other countries settled long ago: to what extent should we be our brothers' and sisters' keepers when it comes to health care? Drawing on the best evidence, he guides readers through the chaotic, secretive, and inefficient way America finances health care, and he offers a penetrating ethical analysis of recent reform proposals. At this point, he argues, the United States appears to have three stark choices: the government can make the rich help pay for the health care of the poor, ration care by income, or control costs. Reinhardt proposes an alternative path: that by age 26 all Americans must choose either to join an insurance arrangement with community-rated premiums, or take a chance on being uninsured or relying on a health insurance market that charges premiums based on health status.An incisive look at the American health care system, Priced Out dispels the confusion, ignorance, myths, and misinformation that hinder effective reform.

    There was atime when this revered organization ranked among the lowest in the country in this area. Within ten years, however, it had climbed to among the highest and has emerged as the thought leader in the space.How did Cleveland Clinic turn itself around so effectively and so quickly?More important, how can you do the same with your organization?In gripping, visceral, on-the ground fashion, Service Fanatics reveals the strategies and tactics the Clinic applied to become one of today's leading patient-experience healthcare organizations--methods that seamlessly translate to any business seeking to improveits customer experience. This strategic guide covers:How the Clinic's leaders redefined the concept of patient experience and developed a strategy to improve itCritical lessons learned regarding organization, recruitment, training, and measuring service excellenceWays in which the Clinic aligned its entire workforce around its Patients First strategyHow leaders improved the critical element of physician communicationRather than view patients simply as sick people who need treatment, Cleveland Clinic sees them also as important stakeholders in the organization's success. Patients are customers--who desire, pay for, and deserve the best possible care and experience during what is often a challenging time in their lives.Featuring customer service case studies, as well as invaluable insight from C-level executives at top corporations in various industries, Service Fanatics provides actionable lessons for any manager and business leader beyond healthcare.Whether you run a healthcare institution, nonprofit, or for-profit business, Service Fanatics will help you create the kind of customer experience that promises to transform your organization into an industry powerhouse.

    Acclaimed for its readability and presentation of current knowledge, this textbook's philosophy is that OB knowledge is for everyone, not just traditional managers. The new reality is that everyone - sales representatives, production employees, physicians - needs OB knowledge to successfully work in and around organizations. Organizational Behavior is unparalleled in its ability to engage students by bringing cutting edge OB concepts closer to reality through the 'theory-practice link' approach. McShane and Von Glinow help readers connect OB theories to emerging workplace realities through hundreds of fascinating real-life stories from across the United States and around the world. be the source of the hottest topics, such as: employee engagement, resilience, four-drive theory, blogs and wikis, psychological harassment, learning orientation, Schwartz's values model, separating socioemotional from constructive conflict, and much, much, more.

    Each case includes an extended discussion, definition of terms, clinical pearls, and USMLE format review questions. This interactive learning system is proven to improve shelf-exam scores and helps students to learn in the context of real patients insted of simply memorizing.

    Legendary celebrities like Liberace and Phyllis Diller attribute their success to reading the book. “I didn’t get my start until I was 37. It was very, very difficult for me. I had a frequently unemployed husband and a house full of kids. My first advice to anyone is to read The Magic of Believing. It changed my life. Read it and absorb the ideas that he puts forth in the book. You won’t even think of your age or the obstacles in your way; you’ll think of your dream, and how to keep focused on your dream.” - Phyllis DillerThat life-changing book started with the book you’re about to read: T.N.T.—It Rocks the Earth.As Claude Bristol’s business associate wrote: “In T.N.T.—It Rocks the Earth, you are told exactly how to acquire a wonderful secret, that Power, or whatever you wish to call it, which, when accepted and developed through a process of right thinking, creates a philosophy of life which sweeps away all obstacles and brings that which every human desires: success, happiness and contentment.Do exactly as he says, put his plan into operation—and I also promise you that almost over night you will be transformed and the things for which you have wished all your life will be yours. Your fears, trials and tribulations will fade into the mists. The door of yesterday will be closed forever. A grand and glorious feeling will engulf you and you will smile, and when you do, the world will smile with you.I know it. I believe it and it is so.“– Frank W. CampThis 1932 hard-to-find classic will rock YOUR life!