In 1875, tuberculosis was the deadliest disease in the world, accountable for a third of all deaths. A diagnosis of TB—often called consumption—was a death sentence. Then, in a triumph of medical science, a German doctor named Robert Koch deployed an unprecedented scientific rigor to discover the bacteria that caused TB. Koch soon embarked on a remedy—a remedy that would be his undoing.   When Koch announced his cure for consumption, Arthur Conan Doyle, then a small-town doctor in England and sometime writer, went to Berlin to cover the event. Touring the ward of reportedly cured patients, he was horrified. Koch’s "remedy" was either sloppy science or outright fraud.   But to a world desperate for relief, Koch’s remedy wasn’t so easily dismissed. As Europe’s consumptives descended upon Berlin, Koch urgently tried to prove his case. Conan Doyle, meanwhile, returned to England determined to abandon medicine in favor of writing. In particular, he turned to a character inspired by the very scientific methods that Koch had formulated: Sherlock Holmes.   Capturing the moment when mystery and magic began to yield to science, The Remedy chronicles the stunning story of how the germ theory of disease became a true fact, how two men of ambition were emboldened to reach for something more, and how scientific discoveries evolve into social truths.

    Encompassing a grand sweep of human history, A History of the World in 100 Objects begins with one of the earliest surviving objects made by human hands, a chopping tool from the Olduvai gorge in Africa, and ends with objects which characterise the world we live in today. Seen through MacGregor's eyes, history is a kaleidoscope - shifting, interconnected, constantly surprising, and shaping our world today in ways that most of us have never imagined. A stone pillar tells us about a great Indian emperor preaching tolerance to his people; Spanish pieces of eight tell us about the beginning of a global currency; and an early Victorian tea-set speaks to us about the impact of empire. An intellectual and visual feast, this is one of the most engrossing and unusual history books published in years. 'Brilliant, engagingly written, deeply researched' Mary Beard, Guardian 'A triumph: hugely popular, and rightly lauded as one of the most effective and intellectually ambitious initiatives in the making of 'public history' for many decades' Sunday Telegraph 'Highly intelligent, delightfully written and utterly absorbing ' Timothy Clifford, Spectator 'This is a story book, vivid and witty, shining with insights, connections, shocks and delights' Gillian Reynolds Daily Telegraph

    In prehistoric caves, drummers used natural acoustics to recreate natural sound. In classical Europe, orators turned the human voice into a lyrical instrument. In Buddhist temples, the icons' ears were exaggerated to represent their spiritual power. And in modern metropolises we are battered by the roar of sound that surrounds us. In the first narrative history of the subject which puts humans at its centre, and coinciding with the author's major Radio 4 series on the same subject, acclaimed historian David Hendy describes the history of noise - which is also the history of listening. As he puts it himself: 'By thinking about sound and listening, I want to get closer to what it felt like to live in the past or be caught up in the major events of history. The book is a chance for readers to discover more of the personal and social background to those stories featured in the radio series.' This unusual book reveals fascinating changes in how we have understood our fellow human humans and the world around us. For although we might see ourselves inhabiting a visual world, our lives are shaped by our need to hear and be heard.

    At the same time, he was immersed in street life. Today he is a cutting-edge neuroscientist—Columbia University's first tenured African American professor in the sciences—whose landmark, controversial research is redefining our understanding of addiction.In this provocative and eye-opening memoir, he recalls his journey of self-discovery and weaves his past and present. Hart goes beyond the hype of the antidrug movement as he examines the relationship among drugs, pleasure, choice, and motivation, both in the brain and in society. His findings shed new light on common ideas about race, poverty, and drugs, and explain why current policies are failing.Though Hart escaped neighborhoods that were dominated by entrenched poverty and the knot of problems associated with it, he has not turned his back on his roots. Determined to make a difference, he tirelessly applies his scientific research to help save real lives. But balancing his former street life with his achievements today has not been easy—a struggle he reflects on publicly for the first time.A powerful story of hope and change, of a scientist who has dedicated his life to helping others, High Price will alter the way we think about poverty, race, and addiction—and how we can effect change.

    In 1950, only 22 percent of American adults were single. Today, more than 50 percent of American adults are single, and 31 million, roughly one out of every seven adults, live alone. People who live alone make up 28 percent of all U.S. households, which makes them more common than any other domestic unit, including the nuclear family. In Going Solo, renowned sociologist and author Eric Klinenberg proves that these numbers are more than just a passing trend. They are, in fact, evidence of the biggest demographic shift since the Baby Boom: we are learning to go solo, and crafting new ways of living in the process.Klinenberg explores the dramatic rise of solo living, and examines the seismic impact it’s having on our culture, business, and politics. Though conventional wisdom tells us that living by oneself leads to loneliness and isolation, Klinenberg shows that most solo dwellers are deeply engaged in social and civic life. In fact, compared with their married counterparts, they are more likely to eat out and exercise, go to art and music classes, attend public events and lectures, and volunteer. There’s even evidence that people who live alone enjoy better mental health than unmarried people who live with others and have more environmentally sustainable lifestyles than families, since they favor urban apartments over large suburban homes. Drawing on over three hundred in-depth interviews with men and women of all ages and every class, Klinenberg reaches a startling conclusion: in a world of ubiquitous media and hyperconnectivity, this way of life can help us discover ourselves and appreciate the pleasure of good company.With eye-opening statistics, original data, and vivid portraits of people who go solo, Klinenberg upends conventional wisdom to deliver the definitive take on how the rise of living alone is transforming the American experience. Going Solo is a powerful and necessary assessment of an unprecedented social change.

    David Agus tackles these fundamental questions and dismantles misperceptions about what “health” really means. Presenting an eye-opening picture of the human body and all the ways it works—and fails—Dr. Agus shows us how a new perspective on our individual health will allow us to achieve a long, vigorous life. Offering insights and access to powerful new technologies that promise to transform medicine, Dr. Agus emphasizes his belief that there is no “right” answer, no master guide that is “one size fits all.” Each one of us must get to know our bodies in uniquely personal ways, and he shows us exactly how to do that. A bold call for all of us to become our own personal health advocates, The End of Illness is a moving departure from orthodox thinking.

    He demonstrates how the explosion of rational thought and scientific innovation during the Enlightenment began to change our understanding of the flesh and its relation to the soul. No longer simply a "mortal coil," the body eventually became the location, and source, of our conscious selves. Porter examines this paradigm shift through the eyes of the great thinkers of history, from Descartes to Voltaire to Lord Byron, summarizing and explicating their beliefs "in a prose that leaps resplendently from the page" (Harper's).

    Myers in his quest for unusual case studies as he unravels medical mysteries.

    It shows how political orientations across space and time arise from three clusters of measurable personality traits. These clusters entail opposing attitudes toward tribalism, inequality, and differing perceptions of human nature. Together, these traits are by far the most powerful cause of left-right voting, even leading people to regularly vote against their economic interests.      As this book explains, our political personalities also influence our likely choice of a mate, and shape society's larger reproductive patterns. Most importantly of all, it tells the evolutionary stories of these crucial personality traits, which stem from epic biological conflicts.     Based on dozens of exciting new insights from primatology, genetics, neuroscience, and anthropology, this groundbreaking work brings core concepts to life through current news stories and personalities. For instance, readers will meet Glenn Beck and Hugo Chavez and come to understand the underlying evolutionary forces they represent. By blending serious research with relevant contemporary examples, Our Political Nature casts important light onto the ideological clashes that so dangerously divide and imperil our world today.

    

    Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.

    In the midst of all this death, a bizarre disease appeared in Europe. Eventually known as encephalitis lethargica, or sleeping sickness, it would spread across the world, leaving millions dead or locked in institutions. Then, in 1927, it would disappear as suddenly as it had arrived-or so the doctors at first thought. Asleep, set in 1920s and '30s New York, follows a group of neurologists through hospitals and insane asylums as they try to solve this worldwide epidemic. The symptoms could include not only unending sleep but dangerous insomnia, facial tics, catatonia, Parkinson's, and even violent insanity. Molly Caldwell Crosby, acclaimed author of The American Plague, explores the frightening history of this forgotten disease- and details the frantic effort to conquer it before it strikes again.

    . . life has just begun! It is the beginning of a very exciting and fulfilling time, full of pleasure beyond your wildest dreams!Dr. Northrup believes that it’s time for you to step forward and learn to enjoy the best years of your life! Even though studies show that menopause doesn’t decrease libido, ease of reaching orgasm, or sexual satisfaction, the majority of menopausal women aren’t experiencing the pleasure and sexual satisfaction that is their birthright. It is a long-held misconception that menopause signals “the beginning of the end,” and nothing could be further from the truth.In this fascinating book, Dr. Northrup candidly guides you toward experiencing life after 50 as the most pleasurable time of your life!

    In "Everyday Cooking with Dr. Dean Ornish," Dr. Ornish teaches you that you don't have to make compromises in your diet. You can enjoy fast, easy-to-prepare meals that are delicious and nutritious, made with familiar, inexpensive, and easy-to-find ingredients. Dr. Ornish and his colleagues present simple yet extraordinary recipes for making fresh, delicious, everyday meals. These time-saving recipes are organized into seasonal menus to take advantage of the freshest ingredients. In addition to offering a tempting selection of recipes, Dr. Ornish gives clear, detailed instructions that interweave techniques, and helpful sidebars; advice on using leftovers, suggestions for alternative ways to season or serve a dish, how to keep a plentiful pantry, a shop-smart guide with supermarket tips and traps, how to equip your low-fat kitchen, how to cook legumes and grains, how to pack a better lunch box, how to choose better bread, and scores of other helpful tips. For the millions who were inspired by Dr. Ornish's previous books, this companion audio makes his way of eating fast and fun, easy and extra ordinary. Drawing on his work training others to adopt his program, Dr. Ornish presents recipes that are extremely low in fat and cholesterol and high in flavor. These simple choices may result in powerful changes in your health and well-being.

    The Repository for Germinal Choice–nicknamed the Nobel Prize sperm bank–opened to notorious fanfare in 1980, and for two decades, women flocked to it from all over the country to choose a sperm donor from its roster of Nobel-laureate scientists, mathematical prodigies, successful businessmen, and star athletes. But the bank quietly closed its doors in 1999–its founder dead, its confidential records sealed, and the fate of its children and donors unknown. In early 2001, award-winning columnist David Plotz set out to solve the mystery of the Nobel Prize sperm bank.Plotz wrote an article for Slate inviting readers to contact him–confidentially–if they knew anything about the bank. The next morning, he received an email response, then another, and another–each person desperate to talk about something they had kept hidden for years. Now, in The Genius Factory, Plotz unfolds the full and astonishing story of the Nobel Prize sperm bank and its founder’s radical scheme to change our world.Believing America was facing genetic catastrophe, Robert Graham, an eccentric millionaire, decided he could reverse the decline by artificially inseminating women with the sperm of geniuses. In February 1980, Graham opened the Repository for Germinal Choice and stocked it with the seed of gifted scientists, inventors, and thinkers. Over the next nineteen years, Graham’s “genius factory” produced more than two hundred children.What happened to them? Were they the brilliant offspring that Graham expected? Did any of the “superman” fathers care about the unknown sons and daughters who bore their genes? What were the mothers like? Crisscrossing the country and logging countless hours online, Plotz succeeded in tracking down previously unknown family members–teenage half-brothers who ended up following vastly different paths, mothers who had wondered for years about the identities of the donors they had selected on the basis of code names and brief character profiles, fathers who were proud or ashamed or simply curious about the children who had been created from their sperm samples. The children of the “genius factory” are messengers from the future–a future that is bearing down on us fast. What will families be like when parents routinely “shop” for their kids’ genes? What will children be like when they’re programmed for greatness? In this stunning, eye-opening book, one of our finest young journalists previews America’s coming age of genetic expectations.From the Hardcover edition.