As he takes us on these myriad travels, Lopez also probes the long history of humanity's quests and explorations, including the prehistoric peoples who trekked across Skraeling Island in northern Canada, the colonialists who plundered Central Africa, an enlightenment-era Englishman who sailed the Pacific, a Native American emissary who found his way into isolationist Japan, and today's ecotourists in the tropics. Throughout his journeys--to some of the hottest, coldest, and most desolate places on the globe--and via friendships he forges along the way with scientists, archaeologists, artists and local residents, Lopez searches for meaning and purpose in a broken world. Horizon is a revelatory, epic work that voices concern and frustration along with humanity and hope--a book that makes you see the world differently, and that is the crowning achievement by one of America's great thinkers and most humane voices.

    From distressed small communities in Central Appalachia to wealthy suburbs; from disparate cities to once-idyllic farm towns; it's a heartbreaking trajectory that illustrates how this national crisis has persisted for so long and become so firmly entrenched. Beginning with a single dealer who lands in a small Virginia town and sets about turning high school football stars into heroin overdose statistics, Macy endeavors to answer a grieving mother's question-why her only son died-and comes away with a harrowing story of greed and need. From the introduction of OxyContin in 1996, Macy parses how America embraced a medical culture where overtreatment with painkillers became the norm. In some of the same distressed communities featured in her bestselling book Factory Man, the unemployed use painkillers both to numb the pain of joblessness and pay their bills, while privileged teens trade pills in cul-de-sacs, and even high school standouts fall prey to prostitution, jail, and death.Through unsparing, yet deeply human portraits of the families and first responders struggling to ameliorate this epidemic, each facet of the crisis comes into focus. In these politically fragmented times, Beth Macy shows, astonishingly, that the only thing that unites Americans across geographic and class lines is opioid drug abuse. But in a country unable to provide basic healthcare for all, Macy still finds reason to hope-and signs of the spirit and tenacity necessary in those facing addiction to build a better future for themselves and their families.

    

    International in scope, this series of non-fiction trade paperbacks offers books that explore the lives, customs and thoughts of peoples and cultures around the world.

    Today, says Dale Purves, the dominant research agenda may have taken us as far as it can--and neuroscientists may be approaching a paradigm shift. In this highly personal book, Purves reveals how we got to this point and offers his notion of where neuroscience may be headed next. Purves guides you through a half-century of the most influential ideas in neuroscience and introduces the extraordinary scientists and physicians who created and tested them. Purves offers a critical assessment of the paths that neuroscience research has taken, their successes and their limitations, and then introduces an alternative approach for thinking about brains. Building on new research on visual perception, he shows why common ideas about brain networks can't be right and uncovers the factors that determine our subjective experience. The resulting insights offer a deeper understanding of what it means to be human. - Why we need a better conception of what brains are trying to do and how they do it Approaches to understanding the brain over the past several decades may be at an impasse - The surprising lessons that can be learned from what we see How complex neural processes owe more to trial-and-error experience than to logical principles - Brains--and the people who think about them Meet some of the extraordinary individuals who've shaped neuroscience - The -ghost in the machine- problem The ideas presented further undermine the concept of free will

    After World War II, Don's work with the Air Force brought them to Colorado, where their twelve children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins—aspiration, hard work, upward mobility, domestic harmony—and they worked hard to play their parts. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the ten Galvin boys, one after another, were diagnosed as schizophrenic. How could all this happen to one family?What took place inside the house on Hidden Valley Road was so extraordinary that the Galvins became one of the first families to be studied by the National Institute of Mental Health. Their story offers a shadow history of the science of schizophrenia, from the era of institutionalization, lobotomy, and the schizophrenogenic mother to the search for genetic markers for the disease, always amid profound disagreements about the nature of the illness itself. And unbeknownst to the Galvins, samples of their DNA informed decades of genetic research that continues today, offering paths to treatment, prediction, and even eradication of the disease for future generations.With clarity and compassion, bestselling and award-winning author Robert Kolker uncovers one family's unforgettable legacy of suffering, love, and hope.

    On one side are parents, bombarded with stories about the dangers of vaccines, now wary of immunizing their sons and daughters. On the other side are doctors, scared to send kids out of their offices vulnerable to illnesses like whooping cough and measles--the diseases of their grandparents.How did anyone come to view vaccines with horror? The answer is rooted in one of the most powerful citizen activist movements in our nation's history. In Deadly Choices, infectious disease expert Paul Offit relates the shocking story of anti-vaccine America--its origins, leaders, influences, and impact. Offering strategies to keep us from returning to an era when children routinely died from infections, Deadly Choices is a vigorous and definitive rebuttal of the powerful anti-vaccine movement.

    But in this thought-provoking collection, twenty-eight writers and scholars give engaging, often passionate accounts of their own nation’s history. The countries have been selected to represent every continent and every type of state: large and small; mature democracies and religious autocracies; states that have existed for thousands of years and those born as recently as the twentieth century. Together they contain two-thirds of the world’s population. In the United States, for example, the myth of the nation’s “historylessness” remains strong, but in China history is seen to play a crucial role in legitimizing three thousand years of imperial authority. “History wars” over the content of textbooks rage in countries as diverse as Australia, Russia, and Japan. Some countries, such as Iran or Egypt, are blessed—or cursed—with a glorious ancient history that the present cannot equal; others, such as Germany, must find ways of approaching and reconciling the pain of the recent past.

    Now he looks at the complex and surprising ways the weak can defeat the strong, the small can match up against the giant, and how our goals (often culturally determined) can make a huge difference in our ultimate sense of success. Drawing upon examples from the world of business, sports, culture, cutting-edge psychology, and an array of unforgettable characters around the world, David and Goliath is in many ways the most practical and provocative book Malcolm Gladwell has ever written.

    These essays, stories, music reviews, the occasional chemically-induced rant, and a couple of recipes— because, for whatever reason, everyone seems to love his recipes—represent a cross-section of the past seven years’ worth of Warren’s writing online. From jumping around Britain, Europe and North America to just dragging his carcass up to the local pub for a think, this is the unedited spillage from the inside of the writer’s head during the ’00s. Some of it even makes sense.

    By 1988 she was living at home but was brain dead after a tragic cycle of misunderstanding, over-medication, and culture clash: "What the doctors viewed as clinical efficiency the Hmong viewed as frosty arrogance." The Spirit Catches You and You Fall Down is a tragedy of Shakespearean dimensions, written with the deepest of human feeling. Sherwin Nuland said of the account, "There are no villains in Fadiman's tale, just as there are no heroes. People are presented as she saw them, in their humility and their frailty—and their nobility.

    Whether you’re enraged by Ikea’s Verdanagate, want to know what the Beach Boys have in common with easy Jet or why it’s okay to like Comic Sans, Just My Type will have the answer. Learn why using upper case got a New Zealand health worker sacked. Refer to Prince in the Tafkap years as a Dingbat (that works on many levels). Spot where movies get their time periods wrong and don’t be duped by fake posters on eBay. Simon Garfield meets the people behind the typefaces and along the way learns why some fonts – like men – are from Mars and some are from Venus. From type on the high street and album covers, to the print in our homes and offices, Garfield is the font of all types of knowledge.

    Yet how much of this is mis- or even disinformation? A lot of it is, and your search engine can't tell the difference. As a result, an avalanche of misinformation threatens to overwhelm the discourse we so desperately need to address complex social problems such as climate change, the food and water crises, biodiversity collapse, and emerging threats to public health. This book provides an inoculation against the misinformation epidemic by cultivating scientific habits of mind. Anyone can do it--indeed, everyone must do it if our species is to survive on this crowded and finite planet.This survival guide supplies an essential set of apps for the prefrontal cortex while making science both accessible and entertaining. It will dissolve your fear of numbers, demystify graphs, and elucidate the key concepts of probability, all while celebrating the precise use of language and logic. David Helfand, one of our nation's leading astronomers and science educators, has taught scientific habits of mind to generations in the classroom, where he continues to wage a provocative battle against sloppy thinking and the encroachment of misinformation.

    He untangles the pattern of interconnecting events, the accidents of time, circumstance, and place that gave rise to major inventions of the world. Says Burke, "My purpose is to acquaint the reader with some of the forces that have caused change in the past, looking in particular at eight innovations - the computer, the production line, telecommunications, the airplane, the atomic bomb, plastics, the guided rocket, and television - which may be most influential in structuring our own futures.... Each one of these is part of a family of similar devices, and is the result of a sequence of closely connected events extending from the ancient world until the present day. Each has enormous potential for humankind's benefit - or destruction."

    They found their livelihood and raised a family in the remote backcountry settlement of Middle Dam, in the Rangeley area. Rich made time after morning chores to write about their lives. We Took to the Woods is an adventure story, written with humor, but it also portrays a cherished dream awakened into full life. First published 1942.