From a fortress-like former bank building, American Pain's doctors distributed massive quantities of oxycodone to hundreds of customers a day, mostly traffickers and addicts who came by the vanload. Inked muscle-heads ran the clinic's security. Former strippers operated the pharmacy, counting out pills and stashing cash in garbage bags. Under their lab coats, the doctors carried guns and it was all legal sort of. American Pain was the brainchild of Chris George, a 27-year-old convicted drug felon. The son of a South Florida home builder, Chris George grew up in ultra-rich Wellington, where Bill Gates, Springsteen, and Madonna kept houses. Thick-necked from weightlifting, he and his twin brother hung out with mobsters, invested in strip clubs, brawled with cops, and grinned for their mug shots. After the housing market stalled, a local doctor clued in the brothers to the burgeoning underground market for lightly regulated prescription painkillers. In Florida, pain clinics could dispense the meds, and no one tracked the patients. Seizing the opportunity, Chris George teamed up with the doctor, and word got out. Just two years later Chris had raked in $40 million, and 90 percent of the pills his doctors prescribed flowed north to feed the rest of the country's insatiable narcotics addiction. Meanwhile, hundreds more pain clinics in the mold of American Pain had popped up in the Sunshine State, creating a gigantic new drug industry. American Pain chronicles the rise and fall of this game-changing pill mill, and how it helped tip the nation into its current opioid crisis, the deadliest drug epidemic in American history. The narrative swings back and forth between Florida and Kentucky, and is populated by a gaudy and diverse cast of characters. This includes the incongruous band of wealthy bad boys, thugs and esteemed physicians who built American Pain, as well as penniless Kentucky clans who transformed themselves into painkiller trafficking rings. It includes addicts whose lives were devastated by American Pain's drugs, and the federal agents and grieving mothers who labored for years to bring the clinic's crew to justice."

    Senator from Massachusetts and bestselling author offers a passionate, inspiring book about why our middle class is under siege and how we can win the fight to save it Senator Elizabeth Warren has long been an outspoken champion of America’s middle class, and by the time the people of Massachusetts elected her in 2012, she had become one of the country’s leading progressive voices. Now, at a perilous moment for our nation, she has written a book that is at once an illuminating account of how we built the strongest middle class in history, a scathing indictment of those who have spent the past thirty-five years undermining working families, and a rousing call to action. Warren grew up in Oklahoma, and she’s never forgotten how difficult it was for her mother and father to hold on at the ragged edge of the middle class. An educational system that offered opportunities for all made it possible for her to achieve her dream of going to college, becoming a teacher, and, later, attending law school. But now, for many, these kinds of opportunities are gone, and a government that once looked out for working families is instead captive to the rich and powerful. Seventy-five years ago, President Franklin Roosevelt and his New Deal ushered in an age of widespread prosperity; in the 1980s, President Ronald Reagan reversed course and sold the country on the disastrous fiction called trickle-down economics. Now, with the election of Donald Trump—a con artist who promised to drain the swamp of special interests and then surrounded himself with billionaires and lobbyists—the middle class is being pushed ever closer to collapse.Written in the candid, high-spirited voice that is Warren’s trademark, This Fight Is Our Fight tells eye-opening stories about her battles in the Senate and vividly describes the experiences of hard-working Americans who have too often been given the short end of the stick. Elizabeth Warren has had enough of phony promises and a government that no longer serves its people—she won’t sit down, she won’t be silenced, and she will fight back.

    They’ve all been solved.” Fortunately, Piot ignored him, and the result has been an exceptional, adventure-filled career. In the 1970s, as a young man, Piot was sent to Central Africa as part of a team tasked with identifying a grisly new virus. Crossing into the quarantine zone on the most dangerous missions, he studied local customs to determine how this disease—the Ebola virus—was spreading. Later, Piot found himself in the field again when another mysterious epidemic broke out: AIDS. He traveled throughout Africa, leading the first international AIDS initiatives there. Then, as founder and director of UNAIDS, he negotiated policies with leaders from Fidel Castro to Thabo Mbeki and helped turn the tide of the epidemic. Candid and engrossing, No Time to Lose captures the urgency and excitement of being on the front lines in the fight against today’s deadliest diseases.

    What began as the chronicle of an imminent and early death became something much more--a powerful exhortation to the living.That Julie Yip-Williams survived infancy was a miracle. Born blind in Vietnam, she narrowly escaped euthanasia at the hands of her grandmother, only to flee with her family the political upheaval of her country in the late 1970s. Loaded into a rickety boat with three hundred other refugees, Julie made it to Hong Kong and, ultimately, America, where a surgeon at UCLA gave her partial sight. She would go on to become a Harvard-educated lawyer, with a husband, a family, and a life she had once assumed would be impossible. Then, at age thirty-seven, with two little girls at home, Julie was diagnosed with terminal metastatic colon cancer, and a different journey began.The Unwinding of the Miracle is the story of a vigorous life refracted through the prism of imminent death. When she was first diagnosed, Julie Yip-Williams sought clarity and guidance through the experience and, finding none, began to write her way through it--a chronicle that grew beyond her imagining. Motherhood, marriage, the immigrant experience, ambition, love, wanderlust, tennis, fortune-tellers, grief, reincarnation, jealousy, comfort, pain, the marvel of the body in full rebellion--this book is as sprawling and majestic as the life it records. It is inspiring and instructive, delightful and shattering. It is a book of indelible moments, seared deep--an incomparable guide to living vividly by facing hard truths consciously.With humor, bracing honesty, and the cleansing power of well-deployed anger, Julie Yip-Williams set the stage for her lasting legacy and one final miracle: the story of her life.

    By 1988 she was living at home but was brain dead after a tragic cycle of misunderstanding, over-medication, and culture clash: "What the doctors viewed as clinical efficiency the Hmong viewed as frosty arrogance." The Spirit Catches You and You Fall Down is a tragedy of Shakespearean dimensions, written with the deepest of human feeling. Sherwin Nuland said of the account, "There are no villains in Fadiman's tale, just as there are no heroes. People are presented as she saw them, in their humility and their frailty—and their nobility.

    The disintegration of this group, a process that has been slowly occurring now for more than forty years, has been reported with growing frequency and alarm, but has never before been written about as searingly from the inside. J. D. Vance tells the true story of what a social, regional, and class decline feels like when you were born with it hung around your neck.The Vance family story begins hopefully in postwar America. J. D.’s grandparents were “dirt poor and in love,” and moved north from Kentucky’s Appalachia region to Ohio in the hopes of escaping the dreadful poverty around them. They raised a middle-class family, and eventually one of their grandchildren would graduate from Yale Law School, a conventional marker of success in achieving generational upward mobility. But as the family saga of Hillbilly Elegy plays out, we learn that J.D.'s grandparents, aunt, uncle, sister, and, most of all, his mother struggled profoundly with the demands of their new middle-class life, never fully escaping the legacy of abuse, alcoholism, poverty, and trauma so characteristic of their part of America. With piercing honesty, Vance shows how he himself still carries around the demons of his chaotic family history.A deeply moving memoir, with its share of humor and vividly colorful figures, Hillbilly Elegy is the story of how upward mobility really feels. And it is an urgent and troubling meditation on the loss of the American dream for a large segment of this country.

    This new edition includes an all-embracing and incisive afterword that examines the current state of health care and our relationship with life as it approaches its terminus. It also discusses how we can take control of our own final days and those of our loved ones.Shewin Nuland's masterful How We Die is even more relevant than when it was first published.

    Gritty, powerful, and ultimately redemptive, Something for the Pain is a revealing glimpse into the fragility of compassion and sanity in the industrial setting of today’s hospitals.

    J. Jacobs read the entire Encyclopædia Britannica from cover to cover in a quest to learn everything in the world. In The Year of Living Biblically, he followed every single rule of the Bible -- from the Ten Commandments right on down to stoning adulterers.Now comes a collection of his most hilarious and thought-provoking experiments yet. In his role as human guinea pig, Jacobs fearlessly takes on a series of life-altering challenges that provides readers with equal parts insight and humor. (And which drives A.J.'s patient wife, Julie, to the brink of insanity.)Among the many adventures:• He outsources his life. A.J. hires a team of people in Bangalore, India, to take care of everything in his life from answering his e-mails to arguing with his spouse.• He spends a month practicing Radical Honesty -- a movement that encourages us to remove the filters between our brains and mouths. (To give you an idea of what happened, the name of the chapter is "I Think You're Fat.")• He goes to the Academy Awards disguised as a movie star to understand the strange and warping effects of fame.• He commits himself to ultimate rationality, using cutting-edge science to make the best decisions possible. It changes the way he makes choices big and small, from what to buy at the grocery store to how to talk to his kids. And his revelations will change how you make decisions, too.• He attempts to follow George Washington's rules of life, uncovering surprising truths about leadership and politics in the twenty-first century. He also spends a lot of time bowing and doffing his hat.• And then there's the month when he followed his wife's every whim -- foot massages, Kate Hudson movies, and all. Depending on your point of view, it's either the best or worst idea in the history of American marriage.A mix of Bill Bryson, George Plimpton, and Malcolm Gladwell, A.J. explores the big issues of our time -- happiness, dating, morality, marriage -- by immersing himself in eye-opening situations. You'll be entertained by these stories -- some of which are new, some of which had their start in Esquire magazine. But you'll also learn to look at life in new ways.The Guinea Pig Diaries is a book packed with both laughs and enlightenment -- and that's a promise we can make with Radical Honesty.

    It was no wonder he gravitated to machines, which could, at least, be counted on.After fleeing his parents and dropping out of high school, his savant-like ability to visualize electronic circuits landed him a gig with KISS, for whom he created their legendary fire-breathing guitars. Later, he drifted into a “real” job, as an engineer for a major toy company. But the higher Robison rose in the company, the more he had to pretend to be “normal” and do what he simply couldn’t: communicate. It wasn’t worth the paycheck.It was not until he was forty that an insightful therapist told him he had the form of autism called Asperger’s syndrome. That understanding transformed the way Robison saw himself—and the world.Look Me in the Eye is the moving, darkly funny story of growing up with Asperger’s at a time when the diagnosis simply didn’t exist. A born storyteller, Robison takes you inside the head of a boy whom teachers and other adults regarded as “defective,” who could not avail himself of KISS’s endless supply of groupies, and who still has a peculiar aversion to using people’s given names (he calls his wife “Unit Two”). He also provides a fascinating reverse angle on the younger brother he left at the mercy of their nutty parents—the boy who would later change his name to Augusten Burroughs and write the bestselling memoir Running with Scissors.Ultimately, this is the story of Robison’s journey from his world into ours, and his new life as a husband, father, and successful small business owner—repairing his beloved high-end automobiles. It’s a strange, sly, indelible account—sometimes alien, yet always deeply human.

    In the book, Sanders shares experiences from the campaign trail and outlines his ideas for continuing a political revolution to fight for a progressive economic, environmental, racial and social justice agenda that creates jobs, raises wages, protects the environment and provides health care for all.

    It killed more people in twenty-four months than AIDS killed in twenty-four years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision of science and epidemic disease. Magisterial in its breadth of perspective and depth of research and now revised to reflect the growing danger of the avian flu, The Great Influenza is ultimately a tale of triumph amid tragedy, which provides us with a precise and sobering model as we confront the epidemics looming on our own horizon.

    Fate landed her at a wildlife sanctuary on the edge of the Amazon jungle where she was assigned to a beautiful and complex puma named Wayra. Wide-eyed, inexperienced, and comically terrified, Laura made the scrappy, make-do camp her home. And in Wayra, she made a friend for life.They weren’t alone, not with over a hundred quirky animals to care for, each lost and hurt in its own way: a pair of suicidal, bra-stealing monkeys, a frustrated parrot desperate to fly, and a pig with a wicked sense of humor. The humans, too, were cause for laughter and tears. There were animal whisperers, committed staff, wildly devoted volunteers, handsome heartbreakers, and a machete-wielding prom queen who carried Laura through. Most of all, there were the jungle—lyrical and alive—and Wayra, who would ultimately teach Laura so much about love, healing, and the person she was capable of becoming.Set against a turbulent and poignant backdrop of deforestation, the illegal pet trade, and forest fires, The Puma Years explores what happens when two desperate creatures in need of rescue find one another.

    It is a place where life and death meet. A place where some families celebrate the most improbable of victories while others face the most devastating of losses. A place where what matters the most in this life is revealed. Trauma Room Two is just such a place. In this collection of short stories, Dr. Green takes the reader inside the hidden emotional landscape of emergency medicine. Based on fifteen years of experience as an ER physician, he reveals the profound moments that often occur in emergency rooms for patients, their families, and the staff that work there.

    Linda Tirado, in her signature brutally honest yet personable voice, takes all of these preconceived notions and smashes them to bits. She articulates not only what it is to be working poor in America (yes, you can be poor and live in a house and have a job, even two), but what poverty is truly like—on all levels. Frankly and boldly, Tirado discusses openly how she went from lower-middle class, to sometimes middle class, to poor and everything in between, and in doing so reveals why “poor people don’t always behave the way middle-class America thinks they should.”