Building a house would entail no more work than planting a seed in the ground. These scenarios may seem far-fetched, but pioneering geneticist George Church and science writer Ed Regis show that synthetic biology is bringing us ever closer to making such visions a reality. In Regenesis, Church and Regis explore the possibilities—and perils—of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. Until now, nature has been the exclusive arbiter of life, death, and evolution; with synthetic biology, we now have the potential to write our own biological future. Indeed, as Church and Regis show, it even enables us to revisit crucial points in the evolution of life and, through synthetic biological techniques, choose different paths from those nature originally took. Such exploits will involve far more than just microbial tinkering. Full-blown genomic engineering will make possible incredible feats, from resurrecting woolly mammoths and other extinct organisms to creating mirror life forms with a molecular structure the opposite of our own. These technologies—far from the out-of-control nightmare depicted in science fiction—have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.

    We find animals and plants where we do because, over time, the continents have moved, separating and uniting in a long, slow dance; because sea levels have risen, cutting off one bit of land from another; because new and barren volcanic islands have risen up from the sea; and because animals and plants vary greatly in their ability to travel, and separation causes the formation of new species. This is the story of how life has responded to, and has in turn altered, the ever-changing Earth. And it includes many fascinating tales--of pygmy mammoths and elephant birds and of radical ideas by bold young scientists.

    The discovery initiated Gessen into a club of sorts: the small (but exponentially expanding) group of people in possession of a new and different way of knowing themselves through what is inscribed in the strands of their DNA. As she wrestled with a wrenching personal decision—what to do with such knowledge—Gessen explored the landscape of this brave new world, speaking with others like her and with experts including medical researchers, historians, and religious thinkers. Blood Matters is a much-needed field guide to this unfamiliar and unsettling territory. It explores the way genetic information is shaping the decisions we make, not only about our physical and emotional health but about whom we marry, the children we bear, even the personality traits we long to have. And it helps us come to terms with the radical transformation that genetic information is engineering in our most basic sense of who we are and what we might become.

    Whether the ailment is a cold, the flu, diabetes, obesity or certain cancers, the likely cause is germs. Our ancient enemies have four families - bacteria, viruses, fungi, and protozoa - and many names: Ebola, E. coli, salmonella, norovirus, gonorrhea. . . Human beings are engaged in a "war on germs," in which we develop ever-more sophisticated weapons and defensive strategies. But it is a war we can never win. Our best plan for staying as healthy is to choose our battles carefully, and try to co-exist with germs as best we can. The Germ Code is a wise, witty and wonderfully readable guide to our relationship with these infinitesimal but infinitely powerful creatures. Microbiologist Jason Tetro takes us outside the lab and shows the enormous influence of germs upon humanity's past, present and future. He unlocks the mysteries of "the germ code" to reveal how these organisms have exploited our every activity and colonized every corner of the earth. From his own research and personal experience, Tetro relates how the most recent flu pandemic happened, how others may have been averted and how more may come about if we aren't careful. He also explains that not every germ is our foe, and offers advice on harnessing the power of good germs to stay healthy and make our planet a better place. The Germ Code is a fascinating journey through an unseen world, an essential manual to living in harmony with germs and a life-enhancing (as well as life-saving!) good read.

    Charting the most cutting-edge scientific breakthroughs, and marshalling his decades of research and clinical practice, Walker explains how we can harness sleep to improve learning, mood and energy levels, regulate hormones, prevent cancer, Alzheimer's and diabetes, slow the effects of aging, and increase longevity. He also provides actionable steps towards getting a better night's sleep every night.

    New emphasis has been given to complexity, networks, and patterns of organisation, leading to a novel kind of 'systemic' thinking. This volume integrates the ideas, models, and theories underlying the systems view of life into a single coherent framework. Taking a broad sweep through history and across scientific disciplines, the authors examine the appearance of key concepts such as autopoiesis, dissipative structures, social networks, and a systemic understanding of evolution. The implications of the systems view of life for health care, management, and our global ecological and economic crises are also discussed. Written primarily for undergraduates, it is also essential reading for graduate students and researchers interested in understanding the new systemic conception of life and its implications for a broad range of professions - from economics and politics to medicine, psychology and law.

    In this book you will find the Hairy Seadevil, the spectacular Sulawesi Naked Bat, and in the depths of the limestone caves in Slovenia, the Olm, a pink, four-legged, sightless salamander that lives for a hundred years. In fascinating vignettes, Flannery offers the true evolutionary tale of how each of these bizarre creatures came to look the way they do. Alongside each historical account is a stunning hand painted color reproduction (life-size in the original painting) by Schouten.Filled with purple-faced apes, jagged toothed dolphins, antlered lizards, Astonishing Animals is a remarkable collection of the world’s most incredible creatures and the stories behind their remarkable survival into a modern age.

    Arthur Allen reveals a history of vaccination that is both illuminated with hope and shrouded by controversy - covering Jenner's discovery to Pasteur's vaccines for rabies and cholera, to those that safeguarded the children of the 20th century.

    However, for naturalist and scientist Nick Davies, the call is an invitation to solve an enduring puzzle: how does the cuckoo get away with laying its eggs in the nests of other birds and tricking them into raising young cuckoos rather than their own offspring?Early observers who noticed a little warbler feeding a monstrously large cuckoo chick concluded the cuckoo's lack of parental care was the result of faulty design by the Creator, and that the hosts chose to help the poor cuckoo. These quaint views of bad design and benevolence were banished after Charles Darwin proposed that the cuckoo tricks the hosts in an evolutionary battle, where hosts evolve better defenses against cuckoos and cuckoos, in turn, evolve better trickery to outwit the hosts.For the last three decades, Davies has employed observation and field experiments to unravel the details of this evolutionary "arms race" between cuckoos and their hosts. Like a detective, Davies and his colleagues studied adult cuckoo behavior, cuckoo egg markings, and cuckoo chick begging calls to discover exactly how cuckoos trick their hosts. For birding and evolution aficionados, Cuckoo is a lyrical and scientifically satisfying exploration of one of nature's most astonishing and beautiful adaptations.

    Recent, massive blooms of billions of jellyfish have clogged power plants, decimated fisheries, and caused millions of dollars of damage. Driven by questions about how overfishing, coastal development, and climate change were contributing to a jellyfish population explosion, Juli embarked on a scientific odyssey. She traveled the globe to meet the biologists who devote their careers to jellies, hitched rides on Japanese fishing boats to see giant jellyfish in the wild, raised jellyfish in her dining room, and throughout it all marveled at the complexity of these alluring and ominous biological wonders.

    Fuzzy brown molds mischievously turn forgotten peaches to slime in the kitchen fruit bowl. And in thousands of other ways, members of the kingdom Fungi do their part to make life on Earth the miracle that it is. In this lively book, George Hudler leads us on a tour of an often-overlooked group of organisms, which differ radically from both animals and plants. Along the way the author stops to ponder the marvels of nature and the impact of mere microbes on the evolution of civilization. Nature's ultimate recyclers not only save us from drowning in a sea of organic waste, but also provide us with food, drink, and a wide array of valuable medicines and industrial chemicals.Some fungi make deadly poisons and psychedelic drugs that have interesting histories in and of themselves, and Hudler weaves tales of those into his scientific account of the nature of the fungi. The role of fungi in the Irish potato famine, in the Salem Witch Trials, in the philosophical writings of Greek scholars, and in the creation of ginger snaps are just a few of the many great moments in history to grace these pages.Hudler moves so easily from discussing human history to exploring scientific knowledge, all with a sense of humor and enthusiasm, that one can well understand why he is an award-winning teacher both at Cornell University as well as nationally. Few, for instance, who read his invitation to get out of your chair and take a short walk will ever again look without curiosity and admiration at the rotten part of the world around them. Magical Mushrooms, Mischievous Molds is full of information that will satisfy history buffs, science enthusiasts, and anyone interested in nature's miracles. Everyone in Hudler's audience will develop a new appreciation of the debt they owe to the molds for such common products as penicillin, wine, and bread.

    He was sleek and prosperous, with a dainty goatee. Though he smiled reassuringly, the poet noticed that he kept a safe distance. In a soothing, urbane voice, the physician explained the treatment: stewed prunes to evacuate the bowels; succulent meats to ease digestion; cinnabar and the sweating tub to cleanse the disease from the skin. The doctor warned of minor side effects: uncontrolled drooling, fetid breath, bloody gums, shakes and palsies. Yet desperate diseases called for desperate remedies, of course.Were Shakespeare's shaky handwriting, his obsession with venereal disease, and his premature retirement connected? Did John Milton go blind from his propaganda work for the Puritan dictator Oliver Cromwell, as he believed, or did he have a rare and devastating complication of a very common eye problem? Did Jonathan Swift's preoccupation with sex and filth result from a neurological condition that might also explain his late-life surge in creativity? What Victorian plague wiped out the entire Brontë family? What was the cause of Nathaniel Hawthorne's sudden demise? Were Herman Melville's disabling attacks of eye and back pain the product of "nervous affections," as his family and physicians believed, or did he actually have a malady that was unknown to medical science until well after his death? Was Jack London a suicide, or was his death the product of a series of self-induced medical misadventures? Why did W. B. Yeats's doctors dose him with toxic amounts of arsenic? Did James Joyce need several horrific eye operations because of a strange autoimmune disease acquired from a Dublin streetwalker? Did writing Nineteen Eighty-Four actually kill George Orwell? The Bard meets House, M.D. in this fascinating untold story of the impact of disease on the lives and works of some the finest writers in the English language. In Shakespeare's Tremor and Orwell's Cough, John Ross cheerfully debunks old biographical myths and suggests fresh diagnoses for these writers' real-life medical mysteries. The author takes us way back, when leeches were used for bleeding and cupping was a common method of cure, to a time before vaccinations, sterilized scalpels, or real drug regimens. With a healthy dose of gross descriptions and a deep love for the literary output of these ten greats, Ross is the doctor these writers should have had in their time of need.

    Ecological design intelligence -- effective adaptation to and integration with nature's processes -- can be applied at all levels of scale, creating revolutionary forms of buildings, landscapes, cities, and technologies.The authors weave together case studies, personal anecdotes, images, and theory to provide a thorough treatment of the concept of ecological design. In the process, they present and explain a series of design principles that can help build a sustainable world with increased efficiency, fewer toxics, less pollution, and healthier natural systems.

    Colin Tudge argues that we are entering a new phase of biology in which, for the first time, biologists are achieving profound insight into life's true diversity and developing the tools to keep track of it. The Variety of Life heralds this new phase. The first part of the book describes why biologists now feel that there could have been as many as 4,000 billion species on Earth since life began. It then discusses the need for classification, beginning with the most basic principles--the strictly practical classification of fishmongers and foresters, who speak of "shellfish" and differentiate "hardwood" from "softwood"--and moves on to explore the intriguing deliberations of the modern "transformed cladists" and the novel contributions of molecular genetics. Part II describes the creatures themselves. It is divided into 24 sections, each describing a different group, illustrated by nearly 50 double-page spreads which present genealogical "trees" that summarize the evolutionary relationships between the creatures in each group. Some sections describe large, comprehensive groups such as the kingdoms of the Animals or the Plants. Others treat similar sub-groups in more detail, such as the Mammals, a class, or the Hominids, a family. In lively and accessible prose, all the significant groups of creatures--both alive and extinct--are described and their relationships clarified. For general readers and serious biologists alike, The Variety of Life offers an unprecedented storehouse of knowledge of life on earth.

    Includes timelines, boxed features on significant medical breakthroughs, fascinating case histories, anecdotes and medical curiosities. Contains 150 color photographs.