Book picks similar to
Designing Clinical Research by Stephen B. Hulley
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medical
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Medicine and Culture
Lynn Payer - 1996
A classic comparative study of medicine and national culture, Medicine and Culture shows us that while doctors regard themselves as servants of science, they are often prisoners of custom.
A Mind of Its Own: How Your Brain Distorts and Deceives
Cordelia Fine - 2005
Indeed, the brain's power is being confirmed every day in new studies and research. But there is a brain we don't generally hear about, a brain we might not want to hear about…the "prima donna within."Exposing the mind's deceptions and exploring how the mind defends and glorifies the ego, Dr. Cordelia Fine illustrates the brain's tendency to self-delusion. Whether it be hindsight bias, wishful thinking, unrealistic optimism, or moral excuse-making, each of us has a slew of inborn mind-bugs and ordinary prejudices that prevent us from seeing the truth about the world and ourselves. With fascinating studies to support her arguments, Dr. Fine takes us on an insightful, rip-roaringly funny tour through the brain you never knew you had.
Artificial Intelligence: A Modern Approach
Stuart Russell - 1994
The long-anticipated revision of this best-selling text offers the most comprehensive, up-to-date introduction to the theory and practice of artificial intelligence. *NEW-Nontechnical learning material-Accompanies each part of the book. *NEW-The Internet as a sample application for intelligent systems-Added in several places including logical agents, planning, and natural language. *NEW-Increased coverage of material - Includes expanded coverage of: default reasoning and truth maintenance systems, including multi-agent/distributed AI and game theory; probabilistic approaches to learning including EM; more detailed descriptions of probabilistic inference algorithms. *NEW-Updated and expanded exercises-75% of the exercises are revised, with 100 new exercises. *NEW-On-line Java software. *Makes it easy for students to do projects on the web using intelligent agents. *A unified, agent-based approach to AI-Organizes the material around the task of building intelligent agents. *Comprehensive, up-to-date coverage-Includes a unified view of the field organized around the rational decision making pa
Chasing My Cure: A Doctor's Race to Turn Hope into Action
David Fajgenbaum - 2019
But things changed dramatically when he began suffering from inexplicable fatigue. In a matter of weeks, his organs were failing and he was read his last rites. Doctors were baffled by his condition, which they had yet to even diagnose. Floating in and out of consciousness, Fajgenbaum prayed for a second chance, the equivalent of a dramatic play to second the game into overtime.Miraculously, Fajgenbaum survived--only to endure repeated near-death relapses from what would eventually be identified as a form of Castleman disease, an extremely deadly and rare condition that acts like a cross between cancer and an autoimmune disorder. When he relapsed while on the only drug in development and realized that the medical community was unlikely to make progress in time to save his life, Fajgenbaum turned his desperate hope for a cure into concrete action: Between hospitalizations he studied his own charts and tested his own blood samples, looking for clues that could unlock a new treatment. With the help of family, friends, and mentors, he also reached out to other Castleman disease patients and physicians, and eventually came up with an ambitious plan to crowdsource the most promising research questions and recruit world-class researchers to tackle them. Instead of waiting for the scientific stars to align, he would attempt to align them himself.More than five years later and now married to his college sweetheart, Fajgenbaum has seen his hard work pay off: A treatment he identified has induced a tentative remission and his novel approach to collaborative scientific inquiry has become a blueprint for advancing rare disease research. His incredible story demonstrates the potency of hope, and what can happen when the forces of determination, love, family, faith, and serendipity collide.
The Psychopath Whisperer: The Science of Those Without Conscience
Kent A. Kiehl - 2014
As Dr. Kent Kiehl shows, psychopaths can be identified by a checklist of symptoms that includes pathological lying; lack of empathy, guilt, and remorse; grandiose sense of self-worth; manipulation; and failure to accept one’s actions. But why do psychopaths behave the way they do? Is it the result of their environment— how they were raised—or is there a genetic component to their lack of conscience? This is the question Kiehl, a protégé of famed psychopath researcher Dr. Robert Hare, was determined to answer as he began his career twenty years ago. To aid in his quest to unravel the psychopathic mind, Kiehl created the first mobile functional MRI scanner to study psychopaths in prison populations. The brains of more than five hundred psychopaths and three thousand other offenders have been scanned by Kiehl’s laboratory—the world’s largest forensic neuroscience repository of its kind. Over the course of The Psychopath Whisperer, we follow the scientific bread crumbs that Kiehl uncovered to show that the key brain structures that correspond with emotional engagement and reactions are diminished in psychopaths, offering new clues to how to predict and treat the disorder. In The Psychopath Whisperer, Kiehl describes in fascinating detail his years working with psychopaths and studying their thought processes— from the remorseless serial killers he meets with behind bars to children whose behavior and personality traits exhibit the early warning signs of psychopathy. Less than 1 percent of the general population meets the criteria for psychopathy. But psychopaths account for a vastly outsized proportion of violent crimes. And as Kiehl shows, many who aren’t psychopaths exhibit some of the behaviors and traits associated with the condition. What do you do if you discover your roommate, or boss, or the person you are dating has traits that define a psychopath? And what does having a diminished limbic region of the brain mean for how the legal system approaches crimes committed by psychopaths? A compelling narrative of cutting-edge science, The Psychopath Whisperer will open your eyes on a fascinating but little understood world, with startling implications for society, the law, and our personal lives.
Brainstorm: The Teenage Brain from the Inside Out
Daniel J. Siegel - 2011
Between the ages of 12 and 24, the brain changes in important and often maddening ways. It's no wonder that many parents approach their child's adolescence with fear and trepidation. According to renowned neuropsychiatrist Daniel Siegel, however, if parents and teens can work together to form a deeper understanding of the brain science behind all the tumult, they will be able to turn conflict into connection and form a deeper understanding of one another. In *Brainstorm*, Siegel illuminates how brain development affects teenagers' behaviour and relationships. Drawing on important new research in the field of interpersonal neurobiology, he explores exciting ways in which understanding how the teenage brain functions can help parents make what is in fact an incredibly positive period of growth, change, and experimentation in their children's lives less lonely and distressing on both sides of the generational divide.
Applied Multivariate Statistical Analysis
Richard A. Johnson - 1982
of Wisconsin-Madison) and Wichern (Texas A&M U.) present the newest edition of this college text on the statistical methods for describing and analyzing multivariate data, designed for students who have taken two or more statistics courses. The fifth edition includes the addition of seve
Better than Human: The Promise and Perils of Enhancing Ourselves
Allen Buchanan - 2011
Biomedical enhancements, he writes, can make us smarter, have better memories, be stronger, quicker, have more stamina, live much longer, be more resistant to disease and to the frailties of aging, and enjoy richer emotional lives. They can even improve our character, or at least strengthen our powers of self-control. In spite of the benefits that biomedical enhancements may bring, many people instinctively reject them. Some worry that we will lose something important-our appreciation for what we have or what makes human beings distinctively valuable. To think clearly about enhancement, Buchanan argues, we have to acknowledge that nature is a mixed bag and that our species has many design flaws. We should be open to the possibility of becoming better than human, while never underestimating the risk that our attempts to improve may backfire.
Using Multivariate Statistics
Barbara G. Tabachnick - 1983
It givessyntax and output for accomplishing many analyses through the mostrecent releases of SAS, SPSS, and SYSTAT, some not available insoftware manuals. The book maintains its practical approach, stillfocusing on the benefits and limitations of applications of a techniqueto a data set -- when, why, and how to do it. Overall, it providesadvanced students with a timely and comprehensive introduction totoday's most commonly encountered statistical and multivariatetechniques, while assuming only a limited knowledge of higher-levelmathematics.
Atlas of Human Anatomy
Frank H. Netter - 1989
In over 540 beautifully colored and easily understood illustrations, it teaches the complete human body with unsurpassed clarity and accuracy. This new edition features 45 revised, 290 relabeled and 17 wholly new plates, drawn fully in the tradition of Frank Netter, and includes more imaging and clinical images than ever before. Six Consulting Editors have worked together to ensure the new edition's accuracy and usefulness in the lecture theatre, classroom and dissection lab. Ninety plates from the book as well as a powerful and varied bank of ancillary material, unique to this atlas, are available online through www.netteranatomy.com.Includes uniquely informative drawings that allow you - and have allowed generations of students - to learn structures with confidence. Associates normal anatomy with an application of that knowledge in a clinical setting. Offers a strong selection of imaging to show you what is happening three dimensionally in the human body, the way you see it in practice.Provides clinically applicable information right from the start, to mirror the way that most anatomy courses are now taught.At www.netteranatomy.com, you'll access...- Over 90 of the most important anatomy illustrations from the book.- Interactive Anatomy Dissection Modules.- Radiographs, CT scans, MRIs, and angiograms, with labels on/off buttons for self testing.- QuickTime movies of stacked, transverse, and sectional images from the Visible Human Project (VHP).- Review Center with Identification Spot Tests and USMLE-style multiple-choice questions.- Integration links to other STUDENT CONSULT titles.- and more!
Pocket Companion for Physical Examination & Health Assessment
Carolyn Jarvis - 1993
Access full-color pathology photos and illustrations, health history, examination steps for each body system, normal versus abnormal findings, lifespan and cross-cultural considerations, related nursing diagnoses, and summary checklists anytime you need them with this convenient clinical tool.Convenient, color-coded design helps you easily locate the information you need.More than 160 full-color illustrations clearly demonstrate important anatomy and physiology concepts, examination steps, and normal and abnormal findings.Age-specific developmental competencies highlight important considerations for pediatric, pregnant, and aging patients.Cultural competency icons alert you to relevant cultural distinctions you may encounter in the clinical setting.Abnormal findings tables provide fast access to key information on many frequently encountered conditions.Spanish-language translation chart helps you ensure accurate, effective examinations of Spanish-speaking patients.Bedside Assessment of the Hospitalized Patient chapter outlines the pertinent assessment steps specific to this patient population.New abnormal findings photos help you recognize and distinguish between abnormal conditions.Additional new full-color examination technique photos clarify exam steps for eyes, nose, mouth, throat, thorax, heart, neck, peripheral vascular, and pediatric exams. Updated evidence-based practice guidelines throughout the guide reflect the most current research and assessment practices.
Thinking in Pictures: My Life with Autism
Temple Grandin - 1995
She also lectures widely on autism—because Temple Grandin is autistic, a woman who thinks, feels, and experiences the world in ways that are incomprehensible to the rest of us. In this unprecedented book, Grandin delivers a report from the country of autism. Writing from the dual perspectives of a scientist and an autistic person, she tells us how that country is experienced by its inhabitants and how she managed to breach its boundaries to function in the outside world. What emerges in Thinking in Pictures is the document of an extraordinary human being, one who, in gracefully and lucidly bridging the gulf between her condition and our own, sheds light on the riddle of our common identity.
Mind Over Mood: Change How You Feel By Changing the Way You Think
Dennis Greenberger - 1995
The book is designed to be used alone or in conjunction with professional treatment. Step-by-step worksheets teach specific skills that have helped hundreds of thousands people conquer depression, panic attacks, anxiety, anger, guilt, shame, low self-esteem, eating disorders, substance abuse and relationship problems. Readers learn to use mood questionnaires to identify, rate, and track changes in feelings; change the thoughts that contribute to problems; follow step-by-step strategies to improve moods; and take action to improve daily living and relationships. The book's large-size format facilitates reading and writing ease. Association for Behavioral and Cognitive Therapies (ABCT) Self-Help Book of Merit
Asleep: The Forgotten Epidemic that Remains One of Medicine's Greatest Mysteries
Molly Caldwell Crosby - 2010
In the midst of all this death, a bizarre disease appeared in Europe. Eventually known as encephalitis lethargica, or sleeping sickness, it would spread across the world, leaving millions dead or locked in institutions. Then, in 1927, it would disappear as suddenly as it had arrived-or so the doctors at first thought. Asleep, set in 1920s and '30s New York, follows a group of neurologists through hospitals and insane asylums as they try to solve this worldwide epidemic. The symptoms could include not only unending sleep but dangerous insomnia, facial tics, catatonia, Parkinson's, and even violent insanity. Molly Caldwell Crosby, acclaimed author of The American Plague, explores the frightening history of this forgotten disease- and details the frantic effort to conquer it before it strikes again.
Stuff: Compulsive Hoarding and the Meaning of Things
Randy O. Frost - 2010
Now they explore the compulsion through a series of compelling case studies in the vein of Oliver Sacks. With vivid portraits that show us the traits by which you can identify a hoarder's piles on sofas and beds that make the furniture useless, houses that can be navigated only by following small paths called goat trails, vast piles of paper that the hoarders "churn" but never discard, even collections of animals and garbage; Frost and Steketee illuminate the pull that possessions exert on all of us. Whether we're savers, collectors, or compulsive cleaners, very few of us are in fact free of the impulses that drive hoarders to the extremes in which they live. For all of us with complicated relationships to our things, Stuff answers the question of what happens when our stuff starts to own us.