Many people think of microbes as germs to be eradicated, but those that live with us—the microbiome—build our bodies, protect our health, shape our identities, and grant us incredible abilities. In this astonishing book, Ed Yong takes us on a grand tour through our microbial partners, and introduces us to the scientists on the front lines of discovery. Yong, whose humor is as evident as his erudition, prompts us to look at ourselves and our animal companions in a new light—less as individuals and more as the interconnected, interdependent multitudes we assuredly are. The microbes in our bodies are part of our immune systems and protect us from disease. Those in cows and termites digest the plants they eat. In the deep oceans, mysterious creatures without mouths or guts depend on microbes for all their energy. Bacteria provide squids with invisibility cloaks, help beetles to bring down forests, and allow worms to cause diseases that afflict millions of people. I Contain Multitudes is the story of these extraordinary partnerships, between the creatures we are familiar with and those we are not. It reveals how we humans are disrupting these partnerships and how we might manipulate them for our own good. It will change both our view of nature and our sense of where we belong in it.

    In The Violinist's Thumb, he explores the wonders of the magical building block of life: DNA.There are genes to explain crazy cat ladies, why other people have no fingerprints, and why some people survive nuclear bombs. Genes illuminate everything from JFK's bronze skin (it wasn't a tan) to Einstein's genius. They prove that Neanderthals and humans bred thousands of years more recently than any of us would feel comfortable thinking. They can even allow some people, because of the exceptional flexibility of their thumbs and fingers, to become truly singular violinists. Kean's vibrant storytelling makes science entertaining, explaining human history and whimsy while showing how DNA will influence our species' future.

    But many people use data in ways they don't even understand, meaning they aren't getting the most from it. Bayesian Statistics the Fun Way will change that.This book will give you a complete understanding of Bayesian statistics through simple explanations and un-boring examples. Find out the probability of UFOs landing in your garden, how likely Han Solo is to survive a flight through an asteroid shower, how to win an argument about conspiracy theories, and whether a burglary really was a burglary, to name a few examples.By using these off-the-beaten-track examples, the author actually makes learning statistics fun. And you'll learn real skills, like how to:- How to measure your own level of uncertainty in a conclusion or belief- Calculate Bayes theorem and understand what it's useful for- Find the posterior, likelihood, and prior to check the accuracy of your conclusions- Calculate distributions to see the range of your data- Compare hypotheses and draw reliable conclusions from themNext time you find yourself with a sheaf of survey results and no idea what to do with them, turn to Bayesian Statistics the Fun Way to get the most value from your data.

    Anthony Fauci a household name, he played a pivotal role in American medicine for over 50 years, as a physician trained in the crucible of medical crisis and an effective researcher who supported medical breakthroughs. Get to know the man behind the sobering and stabilizing presence on TV, and hear the fascinating personal history that equipped him to keep our nation informed about COVID-19.In the summer of 2019, Alan Alda, the acclaimed actor, author and host of the podcast, Clear+Vivid, interviewed Dr. Fauci for the upcoming audio Soldiers of Science. This Audible Original explores a little-known Vietnam-era program that brought the very best and brightest young doctors into government service. Dr. Fauci was one of an elite corps of medical school graduates whose time as clinical researchers at the National Institutes of Health paved the way for life-saving breakthroughs in heart disease, cancer, immunology and the AIDS crisis, not to mention nine Nobel-prize winning discoveries in science (at last count).While editing the full documentary, Alan and the team found themselves deeply moved by Dr. Fauci’s commitment to service, his recollections of his early days at the NIH, and how he coped with the tragedy of the AIDS pandemic. We want our listeners to feel the same sense of inspiration, hope, and the comfort of Dr. Fauci’s insights, so we put together this special preview of Soldiers of Science, highlighting Dr. Fauci’s history. Please enjoy this special excerpt as our salute to all the doctors, nurses, health professionals, first responders, and scientists on the frontlines of the coronavirus pandemic. Soldiers of Science, we thank you for your service.Photo Credit: NIAID©2020 Audible Originals, LLC (P)2020 Audible, Inc.

    He solidified his standing as the nation's foremost political forecaster with his near perfect prediction of the 2012 election. Silver is the founder and editor in chief of FiveThirtyEight.com. Drawing on his own groundbreaking work, Silver examines the world of prediction, investigating how we can distinguish a true signal from a universe of noisy data. Most predictions fail, often at great cost to society, because most of us have a poor understanding of probability and uncertainty. Both experts and laypeople mistake more confident predictions for more accurate ones. But overconfidence is often the reason for failure. If our appreciation of uncertainty improves, our predictions can get better too. This is the "prediction paradox": The more humility we have about our ability to make predictions, the more successful we can be in planning for the future.In keeping with his own aim to seek truth from data, Silver visits the most successful forecasters in a range of areas, from hurricanes to baseball, from the poker table to the stock market, from Capitol Hill to the NBA. He explains and evaluates how these forecasters think and what bonds they share. What lies behind their success? Are they good-or just lucky? What patterns have they unraveled? And are their forecasts really right? He explores unanticipated commonalities and exposes unexpected juxtapositions. And sometimes, it is not so much how good a prediction is in an absolute sense that matters but how good it is relative to the competition. In other cases, prediction is still a very rudimentary-and dangerous-science.Silver observes that the most accurate forecasters tend to have a superior command of probability, and they tend to be both humble and hardworking. They distinguish the predictable from the unpredictable, and they notice a thousand little details that lead them closer to the truth. Because of their appreciation of probability, they can distinguish the signal from the noise.

    This book will equally deepen the awareness of clinicians and enlighten the lay reader. It is a gift to both.' Donald M. Berwick, MD, MPPIn this highly articulate, down-to-earth, generous book, Dr David Galler tells stories of life and death from his position as Intensive Care specialist at Middlemore Hospital. Written lyrically and warmly, these stories are based on real life events describing the everyday dilemmas and challenges that doctors and patients commonly face.It aims to explain and demystify much of the work doctors do, cast light on the workings of the medical establishment and how medicine operates, in the hope that it will encourage patients to seek to be better informed and play a greater role in the decisions that will affect them and their loved ones.It speaks to the resilience of individuals and families and their extraordinary generosity and dignity under the most extreme pressure. This book is about realistic optimism and is a celebration of life.It is also a very personal story about David Galler's life, his family and about his own slow coming of age as a doctor, from the sadness and helplessness he felt about his father's death to at last feeling that he was of some use to his most important patient, his mother.

    His passing on March 6, 1900, would have been unremarkable if a city health officer hadn’t noticed a swollen black lymph node on his groin—a sign of bubonic plague. Empowered by racist pseudoscience, officials rushed to quarantine Chinatown while doctors examined Wong’s tissue for telltale bacteria. If the devastating disease was not contained, San Francisco would become the American epicenter of an outbreak that had already claimed ten million lives worldwide.To local press, railroad barons, and elected officials, such a possibility was inconceivable—or inconvenient. As they mounted a cover-up to obscure the threat, ending the career of one of the most brilliant scientists in the nation in the process, it fell to federal health officer Rupert Blue to save a city that refused to be rescued. Spearheading a relentless crusade for sanitation, Blue and his men patrolled the squalid streets of fast-growing San Francisco, examined gory black buboes, and dissected diseased rats that put the fate of the entire country at risk.In the tradition of Erik Larson and Steven Johnson, Randall spins a spellbinding account of Blue’s race to understand the disease and contain its spread—the only hope of saving San Francisco, and the nation, from a gruesome fate.

    It’s also the most complex. In this remarkable and necessary work, novelist Greg Olear weaves the loose threads of Trump/Russia into a short, easy-to-follow narrative. Dirty Rubles is an ideal primer for those new to the story, a useful review for those already in the know, and a guidebook for the agnostic #MAGA fan—a compelling overview of Trump/Russia that every American should read. "If ignorance is your bliss, Dirty Rubles isn't for you. Greg Olear deliciously tears down that barrier Trump has erected between the truth and the American people. —Cheri Jacobus, USA Today columnist, political pundit and Trump target “While Donald Trump represented the greatest threat to the United States since the Civil War, the US Media abdicated its duty to tell the American people the truth. Luckily, skilled writers and patriots like Greg Olear stepped into the fray, keeping readers rapt as he helped condense complex conspiracy into lucid narrative. Dirty Rubles is a long-form version of that lucidity, a cogent book that will catch people up to speed as they realize the story of the century was kept from them. To help America get back on track, read this book and share its insights with family and friends.” —Eric Garland, strategic analyst, author of Future Inc: How Businesses Can Anticipate and Profit from What’s NEXT and How to Predict the Future and Win.

    What he discovered is a revolution under way—an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease. Deftly excavating and illuminating decades of investigation and analysis, he reveals what we know and don’t know about cancer, showing why a cure remains such a slippery concept. We follow him as he combs through the realms of epidemiology, clinical trials, laboratory experiments, and scientific hypotheses—rooted in every discipline from evolutionary biology to game theory and physics. Cogently extracting fact from a towering canon of myth and hype, he describes tumors that evolve like alien creatures inside the body, paleo-oncologists who uncover petrified tumors clinging to the skeletons of dinosaurs and ancient human ancestors, and the surprising reversals in science’s comprehension of the causes of cancer, with the foods we eat and environmental toxins playing a lesser role. Perhaps most fascinating of all is how cancer borrows natural processes involved in the healing of a wound or the unfolding of a human embryo and turns them, jujitsu-like, against the body. Throughout his pursuit, Johnson clarifies the human experience of cancer with elegiac grace, bearing witness to the punishing gauntlet of consultations, surgeries, targeted therapies, and other treatments. He finds compassion, solace, and community among a vast network of patients and professionals committed to the fight and wrestles to comprehend the cruel randomness cancer metes out in his own family. For anyone whose life has been affected by cancer and has found themselves asking why?, this book provides a new understanding. In good company with the works of Atul Gawande, Siddhartha Mukherjee, and Abraham Verghese, The Cancer Chronicles is endlessly surprising and as radiant in its prose as it is authoritative in its eye-opening science.

    This elegant, humane, and engaging book "captures what we know of the development of what makes us human" (Nature).Visit Armand Marie Leroi on the web: http: //armandleroi.com/index.htmlStepping effortlessly from myth to cutting-edge science,

    If such a plague returned today, taking a comparable percentage of the U.S. population with it, 1.5 million Americans would die.The fascinating, true story of the world's deadliest disease.In 1918, the Great Flu Epidemic felled the young and healthy virtually overnight. An estimated forty million people died as the epidemic raged. Children were left orphaned and families were devastated. As many American soldiers were killed by the 1918 flu as were killed in battle during World War I. And no area of the globe was safe. Eskimos living in remote outposts in the frozen tundra were sickened and killed by the flu in such numbers that entire villages were wiped out.Scientists have recently rediscovered shards of the flu virus frozen in Alaska and preserved in scraps of tissue in a government warehouse. Gina Kolata, an acclaimed reporter for "The New York Times," unravels the mystery of this lethal virus with the high drama of a great adventure story. Delving into the history of the flu and previous epidemics, detailing the science and the latest understanding of this mortal disease, Kolata addresses the prospects for a great epidemic recurring, and, most important, what can be done to prevent it.

    That distinction belongs to Gosnell's Babies." — Alexander Nazaryan, The Atlantic Wire"Very well written ... A must-read for anybody who followed this case." — Jake Tapper, CNNIn this chilling tale set against the backdrop of one of the most controversial issues of our times, award-winning journalist Steve Volk tells the decades-long saga of Kermit Gosnell — the abortion doctor whose clinic in a poor section of Philadelphia was revealed to be a house of horrors.Volk — the only journalist to speak to Gosnell since his conviction and imprisonment — brings the eccentric doctor to life, detailing his past in the early days of the abortion-rights movement and getting him to reveal, for the first time ever, why he did what he did. Was Gosnell a monster, or something else?Volk's powerful storytelling gives us a definitive understanding of a complex character, a horrific case, and a divisive issue.

    Abhay Bang who suffered from Heart disease at the age of 44. You might wonder, how a doctor who never had addiction of cigarette & alcohol throughout his life suffered from heart attack?

    Hurley chronicles today’s diabetes epidemic—how the disease has grown so dramatically, why the American Diabetes Association focuses its attention on just a small handful of available treatments, and why the research being done today doesn’t look beyond accepted types of treatments. Just as Eric Schlosser’s Fast Food Nation uncovered the sordid details leading to an epidemic of obesity, Dan Hurley uncovers the hidden truths of what is being researched—and even more importantly, what is not. Diabetes Rising explores both Type 1 and Type 2 diabetes, one of the leading causes of deaths in the United States. With ground-breaking research and compelling stories seen through an investigative, historical, and narrative lens, Diabetes Rising couples big-picture insight with intimate reporting. The book yields riveting insight into the struggle between the pervasive malady and the medical community’s ongoing search for answers. Informed but not dominated by the author’s own experience as a Type 1 diabetic, Diabetes Rising grants exclusive access to new studies, innovative treatments, and determined patients. Hurley’s sharp, entertaining, and provocative read will change how readers understand diabetes, and the cultures, conditions, and medical climates in which it thrives.

    Dr. John E. McDonough, DPH, a health policy expert who served as an advisor to the late Senator Edward Kennedy, provides a vivid picture of the intense effort required to bring this legislation into law. McDonough clearly explains the ACA’s inner workings, revealing the rich landscape of the issues, policies, and controversies embedded in the law yet unknown to most Americans. In his account of these historic events, McDonough takes us through the process from the 2008 presidential campaign to the moment in 2010 when President Obama signed the bill into law. At a time when the nation is taking a second look at the ACA, Inside National Health Reform provides the essential information for Americans to make informed judgments about this landmark law.