There is every reason to believe that, within a few weeks of its onset, the infection was universally present in the nose and throat of the people, disseminated by mouth spray given off on talking by innumerable carriers and, in addition, by the coughing and sneezing of the sick. Susceptibility was very general, though it varied greatly in degree. Among those who escaped well marked sickness there are few who could not recall having had an occluded or running nose, or a raw feeling in the throat, or a cough, or aches and pains, at some time during the period of the prevalence of the disease, these probably representing the price such persons paid for their immunization." - Dr. Bernard Fantus In many ways, it is hard for modern people living in First World countries to conceive of a pandemic sweeping around the world and killing millions of people, and it is even harder to believe that something as common as influenza could cause such widespread illness and death. Although the flu still takes hundreds of lives each year, most of those lost are very young or old or ill with something else that had already weakened them. In fact, most people contract influenza at least once, and many suffer from the flu several times in their lives and survive it with a minimum amount of medical attention. In 1918, the world was still in the throes of the Great War, the deadliest conflict in human history at that point, but while World War I would be a catastrophic war surpassed only by World War II, an unprecedented influenza outbreak that same year inflicted casualties that would make both wars pale in comparison. An illness, or more likely a collection of illnesses, Spanish influenza quickly spread across the world and may have killed upwards of 100 million people, decimating populations across developed nations and possibly wiping out as much as 5% of the world’s population. If anything, the ongoing war and the censorship maintained by the countries fighting it may have resulted in the actual toll of the outbreak being underestimated based on the way soldiers’ deaths were categorized. World War I may have distracted people about the unprecedented nature of the outbreak, but the most alarming aspect of the outbreak in 1918 was the indiscriminate nature in which the scourge attacked young and old, healthy and unhealthy, and rich and poor alike. In fact, the popular name for the outbreak was a reference to the fact that Spain’s own king was stricken with the disease. While he and President Woodrow Wilson ended up surviving it, former First Lady Rose Cleveland did not. The staggering number of fatalities, and the way in which seemingly anybody could suffer during the outbreak, taught people in the early 20th century that regardless of the tremendous strides made by technology, and no matter how stalemated the war was, nobody was safe from nature itself. Of course, it also demonstrated how much more work could be done to prevent similar occurrences. The 1918 pandemic was neither the first nor the last outbreak of the flu, but it was by far the worst, and it forever changed the face of medicine and public health care in both North America and Europe. The 1918 Spanish Flu Pandemic: The History and Legacy of the World’s Deadliest Outbreak chronicles the devastating disease and the damage it wrought across the globe.

    She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    Most of the skillsets we use today will be irrelevant very soon. Several jobs that exist today will be extinct. AI-powered apps and robots will replace all of them. Corona Pandemic has fast-tracked most of these developments. COVID is rewriting the rules of the game, and AI is automating them. Acute talent deficiency is another pandemic all of us will face very soon. Ok. Let us park the pandemics for some time and talk about our eyesight. The average human eyesight is around 20 by 20. People with 20/30 vision don’t get a driving license in most countries. Anything around 20/1000 is considered blindness. What about our mindsight? Is it 20/20? Much lesser. This book teaches you how to improve your mind-sight. This book introduces four different lenses. These lenses improve the mind-sight significantly. Let's talk about hunger now. Whenever we are hungry, our tummy sends multiple signals to the whole body. Immediately, our eyes start the search operation, and our tongue joins the mission with the taste sensors. The nose filters out the smells, and the mouth begins to secrete the saliva. The whole body works in tandem until we finish a plate or two—most of the time, over-cooperation results in super binging.What about our brains? Is it endowed with all these facilities? How do you know when the brain is hungry? How do you sense if someone feeds it toxic food?All successful leaders in the world have a Mind Position System™ fitted to their brains. The mid positioning system helps them to navigate through any tough and uncomfortable situation. You can also get this if you want. This book teaches you how to install one. Three aspects define your personality:What you haveWhat you dropWhat you pickThe foundational qualities you need to have:High AmbitionA strong Belief systemClarity on goals and ambitionsUndeterred DisciplineABCDs™ in short.The thoughts you need to drop:Unrealistic ExpectationsUnfounded FearGreedHatredEFGH in short.You need to pick four quotients (or lenses):1. Consciousness Quotient 2. Environmental Quotient 3. Digital Quotient4. Number QuotientThat's not all. You will learn to apply the following time tested methods at your workplace:GRIT method to achieve your goalsOPEN method for better communication SIMPLE method to for effective communication and presentation PATH method to get customer delightHEAL method to heal the wounded clients and team membersSUIT method to resolve team conflictsCALM method to overcome fear★★★★★ Jose Cornelio for Readers' FavoriteThe author has the gift of communicating complex ideas in a clear and accessible manner. In a world filled with distractions, Suram teaches leaders how to thrive and successfully accomplish work that matters. This is a book that anyone who wants to be an effective leader should read.

    It covers nearly seventy years of practice from World War II to the present day.The extraordinary situations described here are the result of more than 1,000 years of hands-on bedside knowledge. The vignettes contain wisdom and insight gained the hard way, from long experience in the trenches (sometimes in actual trenches) performing tasks that range from the most humble to the most skilled.These true stories run the gamut from birth to death. They deal with everything from war, ER, ICU, to childbirth, pediatrics, adult care, surgery, home and homeless healthcare, the psych ward, oncology, the nursing home, and finally hospice.The sacrifice and service of these nurses--their courage, kindness, and determination--is breathtaking.If you've ever wanted to know what goes on behind the scenes of a hospital--you've come to the right place.

    The book has undergone three editions, several reprints, and revised reprints in a span of 13 years. There are many biochemistry textbooks in the market. Some of them are purely basic while others are applied, and there are very few books which cover both these aspects together. For this reason, the students learning biochemistry in their undergraduate courses have to depend on multiple books to acquire a sound knowledge of the subject. This book, ‘Biochemistry’ is unique with a simultaneous and equal emphasis on basic and applied aspects of biochemistry. This textbook offers an integration of medical and pure sciences, comprehensively written to meet the curriculum requirements of undergraduate courses in medical, dental, pharmacy, life-sciences and other categories (agriculture, veterinary, etc.). This book is designed to develop in students a sustained interest and enthusiasm to learn and develop the concepts in biochemistry in a logical and stepwise manner. It incorporates a variety of pedagogic aids, besides colour illustrations to help the students understand the subject quickly and to the maximum. The summary and biomedical/clinical concepts are intended for a rapid absorption and assimilation of the facts and concepts in biochemistry. The self-assessment exercises will stimulate the students to think rather than merely learn the subject. In addition, these exercises (essays, short notes, fill in the blanks, multiple choice questions) set at different difficulty levels, will cater to the needs of all the categories of learners.New to This Edition The book offers an integration of medical and pure sciences, and is comprehensively written, revised and updated to meet the curriculum requirements of Medical, Pharmacy, Dental, Veterinary, Biotechnology, Agricultural Sciences, Life Sciences, and others studying Biochemistry as one of the subjects. It is the first text book on Biochemistry in English with multi-colour illustrations by an author from Asia. The use of multicolours is for a clearer understanding of the complicated biochemical reactions. It is written in a lucid style with the subject being presented as an engaging story growing from elementary information to the most recent advances, and with theoretical discussions being supplemented with illustrations, flowcharts, and tables for easy understanding of Biochemistry. It has each chapter beginning with a four-line verse followed by the text, biomedical concepts, a summary, and self-assessment exercises. The lively illustrations and text with appropriate headings and sub-headings in bold type faces facilitate reading path clarity and quick recall. It provides the most recent and essential information on Molecular Biology and Biotechnology, Diabetes, Cancer, Free Radicals, Free radicals and Antioxidants, Prostaglandins, etc. It describes a wide variety of case studies and biochemical correlations and several newer biomedical aspects- Metabolic syndrome, Therapeutic diets, Atkins diet, Trans fatty acids, Epigenetics, Nutrigenomics, Recombinant ribozymes, Membrane transport disorders, Pleural fluid etc. It contains the basics (Bioorganic and Biophysical Chemistry, Tools of Biochemistry, Immunology, and Genetics) for beginners to learn easily Biochemistry, origins of biochemical words, confusables in Biochemistry, principles of Practical Biochemistry, and Clinical Biochemistry Laboratory.

    Sufferers have been ridiculed and labelled perverts. Yet the compulsion to be free of a limb is no imaginary illness. The feelings the condition generates are extraordinarily powerful — so strong that sufferers often seek out the most radical of treatments, and a few unorthodox surgeons risk their reputations to assist.Now we may know why: the condition's deep neurological roots are being unearthed, with startling implications for sufferers, the medical profession and our own understanding of ourselves.In this disturbing story from new science and technology publisher MATTER, acclaimed writer Anil Ananthaswamy delves into the science and accompanies an underground group of sufferers who travel across the world to get the illicit surgery they crave. Join him on a journey that reveals what it's like to be at war with your own body.

     All of us WANT to achieve optimum wellness, but not all of us know how. There are some basic levers that drive health in one of two directions: towards perfection, or towards chronic degenerative disease. If you understand the principles that govern your physiology, you can achieve complete mastery over your own body composition and become the best possible version of yourself. The P:E Diet is the SIMPLEST and MOST PRACTICAL diet and exercise book ever written. Once you understand the core tenets of your biology, you will know HOW to increase your lean mass while decreasing your fat mass—and you will know WHY it works. The P:E Diet breaks down every single dietary strategy into one incredibly simple metric: PROTEIN versus ENERGY. The protein to energy ratio explains EVERY SINGLE DIET PHENOMENON. The P:E Diet breaks down the cause of the obesity epidemic and the solution using this one powerful weapon. This is not ‘paleo’ or ‘keto’ or ‘low carb’ or ‘low fat’ or ‘plants versus animals’ or ‘calorie counting’—instead this is one MASTER CONCEPT that explains the success of EVERY SINGLE DIETARY STRATEGY out there. This book completely TRANSCENDS ALL OF THE DIET CAMPS and explains why they ALL offer some value—and once you understand this underlying principle, you unlock EVERY DIET. The P:E Diet explains EXACTLY why FOOD CHOICE is everything — once you choose WHAT to eat, your body will tell you HOW MUCH to eat. This approach teaches you how to eat INTUITIVELY to achieve your goals, without unnecessary tracking or micromanaging quantity.
 The exercise portion of this book is just as revelatory: all you need for the optimum adaptive response to exercise is to generate MAXIMUM TENSION in your muscles for the MAXIMUM TIME possible. All exercise can be broken down into three exercise motions: PUSH, PULL, and LEGS. This requires NO EQUIPMENT WHATSOEVER and can be accomplished with bodyweight only. By maximizing INTENSITY and FREQUENCY you can build muscle with absolute MINIMUM TIME. Packed with hundreds of photos and illustrations, The P:E Diet is a life-changing knowledge bomb that absolutely anyone and everyone should read. PLEASE NOTE: MAY NOT WORK ON ALL KINDLE DEVICES! Will work well on the Kindle App but may not work on all Kindle devices.

    Ross I.S. Zbar spent his career as a plastic surgeon, in the US as well as abroad in developing countries, mending disease- and trauma-related deformities--and he was never hesitant to make his voice heard as an advocate for better patient care.Then, on a warm December day in 2018, Ross suffered a trauma that nearly took his life, putting him into the hands of his profession in a way he never anticipated. While his life was ultimately saved, his journey to wellness within the conventional medical establishment--from three weeks in the ICU to in-patient rehab--was nothing short of nightmarish. Frequently sedated and physically restrained, he was inundated with mental, emotional, and sensory evidence of an industry gone haywire, experiencing clearly from the patient side what he had only touched on as an advocate.Vowing to be an even stronger voice for change, Ross used the power of his mind to recover faster than any of his doctors predicted. Floating Feathers not only recounts his compelling story but elucidates a thoughtful and authoritative critical call to the members of his beloved profession for a massive overhaul."We possess the technology and the brilliant minds to motivate this level of sweeping change so desperately required," he says. "We simply need to champion it as a non-negotiable priority."This profoundly personal yet overarchingly relative book endeavors to be a vital first step toward that goal.

    They are the powerhouses of our cells, essential for the production and management of energy at cell level. Dr Sarah Myhill, together with Dr John McLaren Howard of Acumen Laboratories and Dr Norman Booth of Mansfield College Oxford, has spent many years studying the relationship between their malfunction and the commonest problem seen by GPs in the UK – fatigue. Their research findings have been published in three scientific papers in the International Journal of Clinical and Experimental Medicine, in 2009, 2012 and 2013. These studies showed that poor functioning of the mitochondria is the central problem in CFS. Patients with the worst mitochondrial function had the worst fatigue and vice versa. This is solid scientific evidence that CFS is a problem with mitochondria and has allowed the objective measurement of fatigue for the first time. With the publication of the third study, which showed that mitochondrial function tests and symptoms improved in patients who took measures to address their mitochondrial problems, Dr Myhill was ready to write this book. Here she explains the importance of healthy mitochondria, how we can measure their functioning and what we can do to keep them healthy, or restore them to health if problems arise. CFS is all in our cells, not in our minds!

    Distinguished by the foremost voices and publications—among them Pulitzer Prize-winner Amy Harmon, Nobel Prize–winner Al Gore, and award-winning and bestselling author Oliver Sacks—this anthology is a comprehensive overview of our most advanced and most relevant scientific inquiries.

    

    Margaret I. Cuomo is inspired to seek out new strategies for waging a smarter war on cancer.This year, about 1.6 million new cases of cancer will be diagnosed and more than 1,500 people will die "per day." We've been asked to accept the disappointing strategy to "manage cancer as a chronic disease." We've allowed pharmaceutical companies to position cancer drugs that extend life by just weeks and may cost $100,000 for a single course of treatment as breakthroughs. Where is the bold leadership that will transform our system from treatment to prevention? Have we forgotten the mission of the National Cancer Act of 1971 to "conquer cancer"?Through an analysis of more than 40 years of medical evidence and interviews with the top cancer researchers, drug company executives, and health policy advisers, Dr. Cuomo reveals intriguing answers to these questions. She shows us how all cancer stakeholders--the pharmaceutical industry, the government, physicians, and concerned Americans--can change the way we view and fight cancer in this country.

    The word conjures up images of horrific diseases sweeping the globe and killing everyone in their path. But such highly lethal illnesses almost never create pandemics. The reality is deadly serious but far more subtle.In Pandemics: What Everyone Needs to Know�, Peter Doherty, who won the Nobel Prize for his work on how the immune system recognizes virus-infected cells, offers an essential guide to one of the truly life-or-death issues of our age. In concise, question-and-answer format, he explains the causes of pandemics, how they can be counteracted with vaccines and drugs, and how we can better prepare for them in the future. Doherty notes that the term "pandemic" refers not to a disease's severity but to its ability to spread rapidly over a wide geographical area. Extremely lethal pathogens are usually quickly identified and confined. Nevertheless, the rise of high-speed transportation networks and the globalization of trade and travel have radically accelerated the spread of diseases. A traveler from Africa arrived in New York in 1999 carrying the West Nile virus; one mosquito bite later, it was loose in the ecosystem. Doherty explains how the main threat of a pandemic comes from respiratory viruses, such as influenza and SARS, which disseminate with incredible speed through air travel. The climate disruptions of global warming, rising population density, and growing antibiotic resistance all complicate efforts to control pandemics. But Doherty stresses that pandemics can be fought effectively. Often simple health practices, especially in hospitals, can help enormously. And research into the animal reservoirs of pathogens, from SARS in bats to HIV in chimpanzees, show promise for our prevention efforts.Calm, clear, and authoritative, Peter Doherty's Pandemics is one of the most critically important additions to the What Everyone Needs to Know� series.What Everyone Needs to Know� is a registered trademark of Oxford University Press.

    He was sleek and prosperous, with a dainty goatee. Though he smiled reassuringly, the poet noticed that he kept a safe distance. In a soothing, urbane voice, the physician explained the treatment: stewed prunes to evacuate the bowels; succulent meats to ease digestion; cinnabar and the sweating tub to cleanse the disease from the skin. The doctor warned of minor side effects: uncontrolled drooling, fetid breath, bloody gums, shakes and palsies. Yet desperate diseases called for desperate remedies, of course.Were Shakespeare's shaky handwriting, his obsession with venereal disease, and his premature retirement connected? Did John Milton go blind from his propaganda work for the Puritan dictator Oliver Cromwell, as he believed, or did he have a rare and devastating complication of a very common eye problem? Did Jonathan Swift's preoccupation with sex and filth result from a neurological condition that might also explain his late-life surge in creativity? What Victorian plague wiped out the entire Brontë family? What was the cause of Nathaniel Hawthorne's sudden demise? Were Herman Melville's disabling attacks of eye and back pain the product of "nervous affections," as his family and physicians believed, or did he actually have a malady that was unknown to medical science until well after his death? Was Jack London a suicide, or was his death the product of a series of self-induced medical misadventures? Why did W. B. Yeats's doctors dose him with toxic amounts of arsenic? Did James Joyce need several horrific eye operations because of a strange autoimmune disease acquired from a Dublin streetwalker? Did writing Nineteen Eighty-Four actually kill George Orwell? The Bard meets House, M.D. in this fascinating untold story of the impact of disease on the lives and works of some the finest writers in the English language. In Shakespeare's Tremor and Orwell's Cough, John Ross cheerfully debunks old biographical myths and suggests fresh diagnoses for these writers' real-life medical mysteries. The author takes us way back, when leeches were used for bleeding and cupping was a common method of cure, to a time before vaccinations, sterilized scalpels, or real drug regimens. With a healthy dose of gross descriptions and a deep love for the literary output of these ten greats, Ross is the doctor these writers should have had in their time of need.

    You might even be worried that these lapses in memory could be an early sign of Alzheimer's or dementia. In reality, for the vast majority of us, these examples of forgetting are completely normal. Why? Because while memory is amazing, it is far from perfect. Our brains aren't designed to remember every name we hear, plan we make, or day we experience. Just because your memory sometimes fails doesn't mean it's broken or succumbing to disease. Forgetting is actually part of being human. In Remember, neuroscientist and acclaimed novelist Lisa Genova delves into how memories are made and how we retrieve them. You'll learn whether forgotten memories are temporarily inaccessible or erased forever and why some memories are built to exist for only a few seconds (like a passcode) while others can last a lifetime (your wedding day). You'll come to appreciate the clear distinction between normal forgetting (where you parked your car) and forgetting due to Alzheimer's (that you own a car). And you'll see how memory is profoundly impacted by meaning, emotion, sleep, stress, and context. Once you understand the language of memory and how it functions, its incredible strengths and maddening weaknesses, its natural vulnerabilities and potential superpowers, you can both vastly improve your ability to remember and feel less rattled when you inevitably forget. You can set educated expectations for your memory, and in doing so, create a better relationship with it. You don't have to fear it anymore. And that can be life-changing.