But molecules, such as water and sugar, are not alive. So how do our cells--assemblies of otherwise "dead" molecules--come to life, and together constitute a living being? In "Life's Ratchet," physicist Peter M. Hoffmann locates the answer to this age-old question at the nanoscale. The complex molecules of our cells can rightfully be called "molecular machines," or "nanobots"; these machines, unlike any other, work autonomously to create order out of chaos. Tiny electrical motors turn electrical voltage into motion, tiny factories custom-build other molecular machines, and mechanical machines twist, untwist, separate and package strands of DNA. The cell is like a city--an unfathomable, complex collection of molecular worker bees working together to create something greater than themselves. Life, Hoffman argues, emerges from the random motions of atoms filtered through the sophisticated structures of our evolved machinery. We are essentially giant assemblies of interacting nanoscale machines; machines more amazing than can be found in any science fiction novel. Incredibly, the molecular machines in our cells function without a mysterious "life force," nor do they violate any natural laws. Scientists can now prove that life is not supernatural, and that it can be fully understood in the context of science. Part history, part cutting-edge science, part philosophy, "Life's Ratchet" takes us from ancient Greece to the laboratories of modern nanotechnology to tell the story of our quest for the machinery of life.

    Jane Goodall was a young secretarial school graduate when the legendary Louis Leakey chose her to undertake a landmark study of chimpanzees in the world. This paperback edition contains 80 photographs and in introduction by Stephen Jay Gould.

    But what would it look like to study the whole of history, from the big bang through the present day -- and even into the remote future? How would looking at the full span of time change the way we perceive the universe, the earth, and our very existence?These were the questions David Christian set out to answer when he created the field of "Big History," the most exciting new approach to understanding where we have been, where we are, and where we are going. In Origin Story, Christian takes readers on a wild ride through the entire 13.8 billion years we've come to know as "history." By focusing on defining events (thresholds), major trends, and profound questions about our origins, Christian exposes the hidden threads that tie everything together -- from the creation of the planet to the advent of agriculture, nuclear war, and beyond.With stunning insights into the origin of the universe, the beginning of life, the emergence of humans, and what the future might bring, Origin Story boldly reframes our place in the cosmos.

    No one can stop him--but he walks away. A miracle? No...dysentery. Microbes saved the Roman Empire. Nearly a millennium later, the microbes of the Black Death ended the Middle Ages, making possible the Renaissance, western democracy, and the scientific revolution. Soon after, microbes ravaged the Americas, paving the way for their European conquest. Again and again, microbes have shaped our health, our genetics, our history, our culture, our politics, even our religion and ethics. This book reveals much that scientists and cultural historians have learned about the pervasive interconnections between infectious microbes and humans. It also considers what our ongoing fundamental relationship with infectious microbes might mean for the future of the human species. The "good side" of history's worst epidemics The surprising debt we owe to killer diseases Where diseases came from... ...and where they may be going Children of pestilence: disease and civilization From Egypt to Mexico, the Romans to Attila the Hun STDs, sexual behavior, and culture How microbes may shape cultural cycles of puritanism and promiscuity

    The story of how we got from there to here is full of fascinating people, and in this elegant, entertaining book, Paul Strathern introduces us to ancient philosophers, medieval alchemists, and the earliest chemists-and to Dimitri Mendeleyev, the card-playing nineteenth-century Russian who claimed that the answers came to him in a dream. "Chemistry has been a neglected area of science writing, and Mendeleyev, the king of chemistry, is a largely forgotten genius. [This book] goes a long way toward correcting this injustice." (Simon Singh, author of Fermat's Last Theorem, in the Sunday Telegraph)

    Join author Douglas Adams and zoologist Mark Carwardine as they take off around the world in search of exotic, endangered creatures.

    They were hunter-gatherers, consummate foraging experts, but taking the world as they found it. Then a revolution occurred – our ancestors’ interaction with other species changed. They began to tame them. The human population boomed; civilization began.In her new book, Tamed, Alice Roberts uncovers the amazing deep history of ten familiar species with incredible wild pasts: dogs, apples and wheat; cattle; potatoes and chickens; rice, maize, and horses – and, finally, humans. Alice Roberts not only reveals how becoming part of our world changed these animals and plants, but shows how they became our allies, essential to the survival and success of our own species – and to our future.Enlightening, wide-ranging and endlessly fascinating, Tamed is an epic story, encompassing hundreds of thousands of years of history and archaeology alongside cutting-edge genetics and anthropology. Yet it is also a deeply personal journey that will change how we see ourselves and the species on which we have left our mark.

    In this masterly synthesis, Arthur Koestler cuts through the sterile distinction between 'sciences' and 'humanities' to bring to life the whole history of cosmology from the Babylonians to Newton. He shows how the tragic split between science and religion arose and how, in particular, the modern world-view replaced the medieval world-view in the scientific revolution of the seventeenth century. He also provides vivid and judicious pen-portraits of a string of great scientists and makes clear the role that political bias and unconscious prejudice played in their creativity.

    It would become the world's most baffling mathematical mystery. Simple, elegant, and utterly impossible to prove, Fermat's Last Theorem captured the imaginations of amateur and professional mathematicians for over three centuries. For some it became a wonderful passion. For others it was an obsession that led to deceit, intrigue, or insanity. In a volume filled with the clues, red herrings, and suspense of a mystery novel, Dr. Amir Aczel reveals the previously untold story of the people, the history, and the cultures that lie behind this scientific triumph. From formulas devised for the farmers of ancient Babylonia to the dramatic proof of Fermat's theorem in 1993, this extraordinary work takes us along on an exhilarating intellectual treasure hunt. Revealing the hidden mathematical order of the natural world in everything from stars to sunflowers, "Fermat's Last Theorem" brilliantly combines philosophy and hard science with investigative journalism. The result: a real-life detective story of the intellect, at once intriguing, thought-provoking, and impossible to put down.

    Lavishly illustrated with over sixty original artworks, All Yesterdays aims to challenge our notions of how prehistoric animals looked and behaved. As a critical exploration of palaeontological art, All Yesterdays asks questions about what is probable, what is possible, and what is commonly ignored.Written by palaeozoologist Darren Naish, and palaeontological artists John Conway and C.M. Kosemen, All Yesterdays is scientifically rigorous and artistically imaginative in its approach to fossils of the past - and those of the future.

    Scientists around the world are currently monitoring the sixth extinction, predicted to be the most devastating extinction event since the asteroid impact that wiped out the dinosaurs. This time around, the cataclysm is us. In prose that is at once frank, entertaining, and deeply informed, The New Yorker writer Elizabeth Kolbert tells us why and how human beings have altered life on the planet in a way no species has before. Interweaving research in half a dozen disciplines, descriptions of the fascinating species that have already been lost, and the history of extinction as a concept, Kolbert provides a moving and comprehensive account of the disappearances occurring before our very eyes. She shows that the sixth extinction is likely to be mankind's most lasting legacy, compelling us to rethink the fundamental question of what it means to be human.

    A group of young scientists, under the guidance of Dr. George Church, the most brilliant geneticist of our time, works to make fantasy reality by sequencing the DNA of a frozen woolly mammoth harvested from above the Arctic circle, and splicing elements of that sequence into the DNA of a modern elephant. Will they be able to turn the hybrid cells into a functional embryo and bring the extinct creatures to life in our modern world?Along with Church and his team of Harvard scientists, a world-famous conservationist and a genius Russian scientist plan to turn a tract of the Siberian tundra into Pleistocene Park, populating the permafrost with ancient herbivores as a hedge against an environmental ticking time bomb.