Scott guides readers through the latest advances in stem cell research in clear, accessible language, telling the stories of the researchers who are exploring the potential of stem cells to cure cancer, grow new organs, and repair the immune system. He also leads readers through a discussion of the question at the heart of the explosive ethical debate: How, as a society, do we balance our responsibilities to the unborn and the sick? Stem Cell Now is essential reading for anyone who wants to build an informed opinion on stem cell research.

    An epic, first-of-its-kind book, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize–winning New York Times journalist.A terminal cancer patient rises from the grave. A medical marvel defies HIV. Two women with autoimmunity discover their own bodies have turned against them. Matt Richtel's An Elegant Defense uniquely entwines these intimate stories with science’s centuries-long quest to unlock the mysteries of sickness and health, and illuminates the immune system as never before.The immune system is our body’s essential defense network, a guardian vigilantly fighting illness, healing wounds, maintaining order and balance, and keeping us alive. Its legion of microscopic foot soldiers—from T cells to “natural killers”—patrols our body, linked by a nearly instantaneous communications grid. It has been honed by evolution over millennia to face an almost infinite array of threats.For all its astonishing complexity, however, the immune system can be easily compromised by fatigue, stress, toxins, advanced age, and poor nutrition—hallmarks of modern life—and even by excessive hygiene. Paradoxically, it is a fragile wonder weapon that can turn on our own bodies with startling results, leading today to epidemic levels of autoimmune disorders.Richtel effortlessly guides readers on a scientific detective tale winding from the Black Plague to twentieth-century breakthroughs in vaccination and antibiotics, to the cutting-edge laboratories that are revolutionizing immunology—perhaps the most extraordinary and consequential medical story of our time. The foundation that Richtel builds makes accessible revelations about cancer immunotherapy, the microbiome, and autoimmune treatments that are changing millions of lives. An Elegant Defense also captures in vivid detail how these powerful therapies, along with our behavior and environment, interact with the immune system, often for the good but always on a razor’s edge that can throw this remarkable system out of balance.Drawing on his groundbreaking reporting for the New York Times and based on extensive new interviews with dozens of world-renowned scientists, Matt Richtel has produced a landmark book, equally an investigation into the deepest riddles of survival and a profoundly human tale that is movingly brought to life through the eyes of his four main characters, each of whom illuminates an essential facet of our “elegant defense.”

    This adventure in science and imagination, which the Medical Tribune said might herald "a Copernican revolution for the life sciences," leads the reader through unexplored jungles and uncharted aspects of mind to the heart of knowledge.In a first-person narrative of scientific discovery that opens new perspectives on biology, anthropology, and the limits of rationalism, The Cosmic Serpent reveals how startlingly different the world around us appears when we open our minds to it.

    The book has the hallmark features for which Lippincott's Illustrated Reviews volumes are so popular: an outline format, over 600 full-color illustrations, end-of-chapter summaries, review questions, plus an entire section of clinical case studies with full-color illustrations. This edition's medical/clinical focus has been sharpened to provide a high-yield review. Five additional case studies have been included, bringing the total to nineteen. Review questions have been reformatted to comply with USMLE Step 1 style, with clinical vignettes.

    The book describes dramatic breakthroughs in our knowledge of how sleep occurs, what it does, and what happens to our health if we do not have enough. The authors consider the impact of modern society, examining the relationship between sleep and our 24/7 culture.

    This is a deeply technical book and focuses on the software engineering skills to ace your interview. The book is over 500 pages and includes 150 programming interview questions and answers, as well as other advice.The full list of topics are as follows:The Interview ProcessThis section offers an overview on questions are selected and how you will be evaluated. What happens when you get a question wrong? When should you start preparing, and how? What language should you use? All these questions and more are answered.Behind the ScenesLearn what happens behind the scenes during your interview, how decisions really get made, who you interview with, and what they ask you. Companies covered include Google, Amazon, Yahoo, Microsoft, Apple and Facebook.Special SituationsThis section explains the process for experience candidates, Program Managers, Dev Managers, Testers / SDETs, and more. Learn what your interviewers are looking for and how much code you need to know.Before the InterviewIn order to ace the interview, you first need to get an interview. This section describes what a software engineer's resume should look like and what you should be doing well before your interview.Behavioral PreparationAlthough most of a software engineering interview will be technical, behavioral questions matter too. This section covers how to prepare for behavioral questions and how to give strong, structured responses.Technical Questions (+ 5 Algorithm Approaches)This section covers how to prepare for technical questions (without wasting your time) and teaches actionable ways to solve the trickiest algorithm problems. It also teaches you what exactly "good coding" is when it comes to an interview.150 Programming Questions and AnswersThis section forms the bulk of the book. Each section opens with a discussion of the core knowledge and strategies to tackle this type of question, diving into exactly how you break down and solve it. Topics covered include• Arrays and Strings• Linked Lists• Stacks and Queues• Trees and Graphs• Bit Manipulation• Brain Teasers• Mathematics and Probability• Object-Oriented Design• Recursion and Dynamic Programming• Sorting and Searching• Scalability and Memory Limits• Testing• C and C++• Java• Databases• Threads and LocksFor the widest degree of readability, the solutions are almost entirely written with Java (with the exception of C / C++ questions). A link is provided with the book so that you can download, compile, and play with the solutions yourself.Changes from the Fourth Edition: The fifth edition includes over 200 pages of new content, bringing the book from 300 pages to over 500 pages. Major revisions were done to almost every solution, including a number of alternate solutions added. The introductory chapters were massively expanded, as were the opening of each of the chapters under Technical Questions. In addition, 24 new questions were added.Cracking the Coding Interview, Fifth Edition is the most expansive, detailed guide on how to ace your software development / programming interviews.

    It discusses new results, along with applications of probability theory to a variety of problems. The book contains many exercises and is suitable for use as a textbook on graduate-level courses involving data analysis. Aimed at readers already familiar with applied mathematics at an advanced undergraduate level or higher, it is of interest to scientists concerned with inference from incomplete information.

    The novel approach taken here banishes determinants to the end of the book and focuses on the central goal of linear algebra: understanding the structure of linear operators on vector spaces. The author has taken unusual care to motivate concepts and to simplify proofs. For example, the book presents - without having defined determinants - a clean proof that every linear operator on a finite-dimensional complex vector space (or an odd-dimensional real vector space) has an eigenvalue. A variety of interesting exercises in each chapter helps students understand and manipulate the objects of linear algebra. This second edition includes a new section on orthogonal projections and minimization problems. The sections on self-adjoint operators, normal operators, and the spectral theorem have been rewritten. New examples and new exercises have been added, several proofs have been simplified, and hundreds of minor improvements have been made throughout the text.

    In case study format, this informative reference answers questions surrounding nuclear energy, the potential of sustainable fossil fuels, and the possibilities of sharing renewable power with foreign countries. While underlining the difficulty of minimizing consumption, the tone remains positive as it debunks misinformation and clearly explains the calculations of expenditure per person to encourage people to make individual changes that will benefit the world at large.

    The text presents a balanced, thorough introduction to the field of physical anthropology that also reflects the current state of the field. The heredity and evolution chapters (Chapters 1-5) have been expanded and updated to reflect the tremendous advances of molecular biology in all phases of physical anthropology, and the hominid evolution chapters (Chapters 8-11) have been reorganized and reinterpreted to reflect current academic thought springing from recent major finds. To make the text more accessible, the Sixth Edition includes many new visuals that, together with the many charts, helpful tables, multimedia, and engaging writing style, will bring the study of physical anthropology to life for today's student.

    Francis Collins, director of the National Institute of Health, 2007 recipient of the Presidential Medal of Freedom, and 15-year head of the Human Genome Project, comes one of the most important medical books of the year: The Language of Life. With accessible, insightful prose, Dr. Collins describes the medical, scientific, and genetic revolution that is currently unlocking the secrets of “personalized medicine,” and offers practical advice on how to utilize these discoveries for you and your family’s current and future health and well-being. In the words of Dr. Jerome Groopman (How Doctors Think), The Language of Life “sets out hope without hype, and will enrich the mind and uplift the heart.”

    With even more of the unparalleled art and thoughtful pedagogy found in the First Edition, coverage of the latest discoveries and theories, and expanded treatment of several key topics, Our Origins, Second Edition, provides students with the tools they need to visualize and remember key concepts and to answer the Big Questions in physical anthropology."

    In How to Clone a Mammoth, Beth Shapiro, evolutionary biologist and pioneer in "ancient DNA" research, walks readers through the astonishing and controversial process of de-extinction. From deciding which species should be restored, to sequencing their genomes, to anticipating how revived populations might be overseen in the wild, Shapiro vividly explores the extraordinary cutting-edge science that is being used--today--to resurrect the past. Journeying to far-flung Siberian locales in search of ice age bones and delving into her own research--as well as those of fellow experts such as Svante Paabo, George Church, and Craig Venter--Shapiro considers de-extinction's practical benefits and ethical challenges. Would de-extinction change the way we live? Is this really cloning? What are the costs and risks? And what is the ultimate goal?Using DNA collected from remains as a genetic blueprint, scientists aim to engineer extinct traits--traits that evolved by natural selection over thousands of years--into living organisms. But rather than viewing de-extinction as a way to restore one particular species, Shapiro argues that the overarching goal should be the revitalization and stabilization of contemporary ecosystems. For example, elephants with genes modified to express mammoth traits could expand into the Arctic, re-establishing lost productivity to the tundra ecosystem.Looking at the very real and compelling science behind an idea once seen as science fiction, How to Clone a Mammoth demonstrates how de-extinction will redefine conservation's future.

    It’ll have you scratching your head wondering why we even bother to go to school.Think Magellan was the first man to circumnavigate the globe, baseball was invented in America, Henry VIII had six wives, Mount Everest is the tallest mountain? Wrong, wrong, wrong, and wrong again. You’ll be surprised at how much you don’t know! Check out THE BOOK OF GENERAL IGNORANCE for more fun entries and complete answers to the following:How long can a chicken live without its head?About two years.What do chameleons do?They don’t change color to match the background. Never have; never will. Complete myth. Utter fabrication. Total Lie. They change color as a result of different emotional states.How many legs does a centipede have?Not a hundred.How many toes has a two-toed sloth?It’s either six or eight.Who was the first American president?Peyton Randolph.What were George Washington’s false teeth made from?Mostly hippopotamus.What was James Bond’s favorite drink?Not the vodka martini.

    It's goal is the successful design and operation of chemical reactors. This text emphasizes qualitative arguments, simple design methods, graphical procedures, and frequent comparison of capabilities of the major reactor types. Simple ideas are treated first, and are then extended to the more complex.