For centuries they have practiced techniques that allow them to run hundreds of miles without rest and chase down anything from a deer to an Olympic marathoner while enjoying every mile of it. Their superhuman talent is matched by uncanny health and serenity, leaving the Tarahumara immune to the diseases and strife that plague modern existence. With the help of Caballo Blanco, a mysterious loner who lives among the tribe, the author was able not only to uncover the secrets of the Tarahumara but also to find his own inner ultra-athlete, as he trained for the challenge of a lifetime: a fifty-mile race through the heart of Tarahumara country pitting the tribe against an odd band of Americans, including a star ultramarathoner, a beautiful young surfer, and a barefoot wonder.With a sharp wit and wild exuberance, McDougall takes us from the high-tech science labs at Harvard to the sun-baked valleys and freezing peaks across North America, where ever-growing numbers of ultrarunners are pushing their bodies to the limit, and, finally, to the climactic race in the Copper Canyons. Born to Run is that rare book that will not only engage your mind but inspire your body when you realize that the secret to happiness is right at your feet, and that you, indeed all of us, were born to run.

    But what if, nonetheless, Einstein got it wrong?Since the 1930s, physicists have noticed an alarming discrepancy between the universe as we see it and the universe that Einstein's theory of relativity predicts. There just doesn't seem to be enough stuff out there for everything to hang together. Galaxies spin so fast that, based on the amount of visible matter in them, they ought to be flung to pieces, the same way a spinning yo-yo can break its string. Cosmologists tried to solve the problem by positing dark matter—a mysterious, invisible substance that surrounds galaxies, holding the visible matter in place—and particle physicists, attempting to identify the nature of the stuff, have undertaken a slew of experiments to detect it. So far, none have.Now, John W. Moffat, a physicist at the Perimeter Institute for Theoretical Physics in Waterloo, Canada, offers a different solution to the problem. The cap­stone to a storybook career—one that began with a correspondence with Einstein and a conversation with Niels Bohr—Moffat's modified gravity theory, or MOG, can model the movements of the universe without recourse to dark matter, and his work chal­lenging the constancy of the speed of light raises a stark challenge to the usual models of the first half-million years of the universe's existence.This bold new work, presenting the entirety of Moffat's hypothesis to a general readership for the first time, promises to overturn everything we thought we knew about the origins and evolution of the universe.

    These writers recount intensely personal and profoundly moving end-of-life accounts that cover a wide spectrum of human experience. All six authors are donating their royalties to a Maine hospice; Down East will also donate 10 percent of proceeds to the same cause.

    Guns, Germs, and Steel: The Fates of Human Societies is a 1997 book by Jared Diamond, professor of geography and physiology at the University of California, Los Angeles (UCLA). In 1998 it won a Pulitzer Prize and the Aventis Prize for Best Science Book. A documentary based on the book and produced by the National Geographic Society was broadcast on PBS in July 2005.

    

    In the majority of cases individuals diagnosed as "brain dead" are the source of the organs without which transplants could not take place. In this compelling and provocative examination, Margaret Lock traces the discourse over the past thirty years that contributed to the locating of a new criterion of death in the brain, and its routinization in clinical practice in North America. She compares this situation with that in Japan where, despite the availability of the necessary technology and expertise, brain death was legally recognized only in 1997, and then under limited and contested circumstances. Twice Dead explores the cultural, historical, political, and clinical reasons for the ready acceptance of the new criterion of death in North America and its rejection, until recently, in Japan, with the result that organ transplantation has been severely restricted in that country. This incisive and timely discussion demonstrates that death is not self-evident, that the space between life and death is historically and culturally constructed, fluid, multiple, and open to dispute. In addition to an analysis of that professional literature on and popular representations of the subject, Lock draws on extensive interviews conducted over ten years with physicians working in intensive care units, transplant surgeons, organ recipients, donor families, members of the general public in both Japan and North America, and political activists in Japan opposed to the recognition of brain death. By showing that death can never be understood merely as a biological event, and that cultural, medical, legal, and political dimensions are inevitably implicated in the invention of brain death, Twice Dead confronts one of the most troubling questions of our era.

    In only a few decades, the medical system has been overrun by organizations seeking to exploit for profit the trust that vulnerable and sick Americans place in their healthcare. Our politicians have proven themselves either unwilling or incapable of reining in the increasingly outrageous costs faced by patients, and market-based solutions only seem to funnel larger and larger sums of our money into the hands of corporations. Impossibly high insurance premiums and inexplicably large bills have become facts of life; fatalism has set in. Very quickly Americans have been made to accept paying more for less. How did things get so bad so fast?Breaking down this monolithic business into the individual industries--the hospitals, doctors, insurance companies, and drug manufacturers--that together constitute our healthcare system, Rosenthal exposes the recent evolution of American medicine as never before. How did healthcare, the caring endeavor, become healthcare, the highly profitable industry? Hospital systems, which are managed by business executives, behave like predatory lenders, hounding patients and seizing their homes. Research charities are in bed with big pharmaceutical companies, which surreptitiously profit from the donations made by working people. Patients receive bills in code, from entrepreneurial doctors they never even saw.The system is in tatters, but we can fight back. Dr. Elisabeth Rosenthal doesn't just explain the symptoms, she diagnoses and treats the disease itself. In clear and practical terms, she spells out exactly how to decode medical doublespeak, avoid the pitfalls of the pharmaceuticals racket, and get the care you and your family deserve. She takes you inside the doctor-patient relationship and to hospital C-suites, explaining step-by-step the workings of a system badly lacking transparency. This is about what we can do, as individual patients, both to navigate the maze that is American healthcare and also to demand far-reaching reform. An American Sickness is the frontline defense against a healthcare system that no longer has our well-being at heart.

    Olsen's poignant autobiographical journey through the darkness of mental illness and the catastrophic consequences that lurk in medicine cabinets around the country offers an honest glimpse into alarming statistics and a health care system ranked last among nineteen industrialized nations worldwide. As a former sales representative in the pharmaceutical industry for several years, Olsen learned firsthand how an unprecedented number of lethal drugs are unleashed in the United States market, but her most heartrending education into the dangers of antidepressants would come as a victim and ultimately, as a survivor.Rigorously researched and documented, Confessions of an Rx Drug Pusher is a moving human drama that shares one woman's unforgettable journey of faith, forgiveness, and healing.AUTHOR BIO Gwendolyn Leslie Olsen spent more than a decade as a sales rep in the pharmaceutical industry working for health care giants such as Johnson & Johnson, Bristol-Myers Squibb and Abbott Laboratories. She is a writer, speaker, and mental health activist who lives outside Austin, Texas.

    Beginning with an obscure discovery in 1896, radioactivity led researchers on a quest for understanding that ultimately confronted the intersection of knowledge and mystery. Mysterious from the start, radioactivity attracted researchers who struggled to understand it. What caused certain atoms to give off invisible, penetrating rays? Where did the energy come from? These questions became increasingly pressing when researchers realized the process seemed to continue indefinitely, producing huge quantities of energy. Investigators found cases where radioactivity did change, forcing them to the startling conclusion that radioactive bodies were transmuting into other substances. Chemical elements were not immutable after all. Radioactivity produced traces of matter so minuscule and evanescent that researchers had to devise new techniques and instruments to investigate them. Scientists in many countries, but especially in laboratories in Paris, Manchester, and Vienna unraveled the details of radioactive transformations. They created a new science with specialized techniques, instruments, journals, and international conferences. Women entered the field in unprecedented numbers. Experiments led to revolutionary ideas about the atom and speculations about atomic energy. The excitement spilled over to the public, who expected marvels and miracles from radium, a scarce element discovered solely by its radioactivity. The new phenomenon enkindled the imagination and awakened ancient themes of literature and myth. Entrepreneurs created new industries, and physicians devised novel treatments for cancer. Radioactivity gave archaeologists methods for dating artifacts and meteorologists a new explanation for the air's conductivity. Their explorations revealed a mysterious radiation from space. Radioactivity profoundly changed science, politics, and culture. The field produced numerous Nobel Prize winners, yet radioactivity's talented researchers could not solve the mysteries underlying the new phenomenon. That was left to a new generation and a new way of thinking about reality. Radioactivity presents this fascinating history in a way that is both accessible and appealing to the general reader. Not merely a historical account, the book examines philosophical issues connected with radioactivity, and relates its topics to broader issues regarding the nature of science.

    Otis Brawley is the chief medical and scientific officer of The American Cancer Society, an oncologist with a dazzling clinical, research, and policy career. How We Do Harm pulls back the curtain on how medicine is really practiced in America. Brawley tells of doctors who select treatment based on payment they will receive, rather than on demonstrated scientific results; hospitals and pharmaceutical companies that seek out patients to treat even if they are not actually ill (but as long as their insurance will pay); a public primed to swallow the latest pill, no matter the cost; and rising healthcare costs for unnecessary—and often unproven—treatments that we all pay for. Brawley calls for rational healthcare, healthcare drawn from results-based, scientifically justifiable treatments, and not just the peddling of hot new drugs.Brawley's personal history – from a childhood in the gang-ridden streets of black Detroit, to the green hallways of Grady Memorial Hospital, the largest public hospital in the U.S., to the boardrooms of The American Cancer Society—results in a passionate view of medicine and the politics of illness in America - and a deep understanding of healthcare today. How We Do Harm is his well-reasoned manifesto for change.

    Nancy Butcher has gathered together some of the most unusual natural cures that have been proven effective today, and even throws in some unbelievable and-thankfully-abandoned therapies from times past.Filled with case histories of unique illnesses, historic documentation of strange medical practices, and the author's own insightful commentary, this book explains not only how to cure headaches, sleep better, and improve your sex life, but also that people with Cotard's syndrome actually believe they are dead.

    It can also mean the humbler tools of everyday cooking and eating: a wooden spoon and a skillet, chopsticks and forks.Since prehistory, humans have braved sharp knives, fire, and grindstones to transform raw ingredients into something delicious - or at least edible. Tools shape what we eat, but they have also transformed how we consume, and how we think about, our food. Technology in the kitchen does not just mean the Pacojets and sous-vide of the modernist kitchen. It can also mean the humbler tools of everyday cooking and eating: a wooden spoon and a skillet, chopsticks and forks. In Consider the Fork, award-winning food writer Bee Wilson provides a wonderful and witty tour of the evolution of cooking around the world, revealing the hidden history of everyday objects we often take for granted. Knives - perhaps our most important gastronomic tool - predate the discovery of fire, whereas the fork endured centuries of ridicule before gaining widespread acceptance; pots and pans have been around for millennia, while plates are a relatively recent invention. Many once-new technologies have become essential elements of any well-stocked kitchen - mortars and pestles, serrated knives, stainless steel pots, refrigerators. Others have proved only passing fancies, or were supplanted by better technologies; one would be hard pressed now to find a water-powered egg whisk, a magnet-operated spit roaster, a cider owl, or a turnspit dog. Although many tools have disappeared from the modern kitchen, they have left us with traditions, tastes, and even physical characteristics that we would never have possessed otherwise. Blending history, science, and anthropology, Wilson reveals how our culinary tools and tricks came to be, and how their influence has shaped modern food culture. The story of how we have tamed fire and ice and wielded whisks, spoons, and graters, all for the sake of putting food in our mouths, Consider the Fork is truly a book to savor.

    From the mid-nineteenth century to the early twentieth, over 250 institutions for the insane were built throughout the United States; by 1948, they housed more than a half million patients. The blueprint for these hospitals was set by Pennsylvania hospital superintendent Thomas Story Kirkbride: a central administration building flanked symmetrically by pavilions and surrounded by lavish grounds with pastoral vistas. Kirkbride and others believed that well-designed buildings and grounds, a peaceful environment, a regimen of fresh air, and places for work, exercise, and cultural activities would heal mental illness. But in the second half of the twentieth century, after the introduction of psychotropic drugs and policy shifts toward community-based care, patient populations declined dramatically, leaving many of these beautiful, massive buildings--and the patients who lived in them--neglected and abandoned. Architect and photographer Christopher Payne spent six years documenting the decay of state mental hospitals like these, visiting seventy institutions in thirty states. Through his lens we see splendid, palatial exteriors (some designed by such prominent architects as H. H. Richardson and Samuel Sloan) and crumbling interiors--chairs stacked against walls with peeling paint in a grand hallway; brightly colored toothbrushes still hanging on a rack; stacks of suitcases, never packed for the trip home. Accompanying Payne's striking and powerful photographs is an essay by Oliver Sacks (who described his own experience working at a state mental hospital in his book Awakenings). Sacks pays tribute to Payne's photographs and to the lives once lived in these places, "where one could be both mad and safe."

    From blurry vision, to crooked teeth, ACLs that tear at alarming rates and spines that seem to spend a lifetime falling apart, it's a curious thing that human beings have beaten the odds as a species. After all, we're the only survivors on our branch of the tree of life. Why is it that human mothers have such a life-endangering experience giving birth? And why are there entire medical specialties for teeth and feet? In this funny, wide-ranging and often surprising book, biologist Alex Bezzerides tells us just where we inherited our adaptable, achy, brilliant bodies in the process of evolution.The book traces the delightfully unexpected answers to these questions and many more:Why do we blink?Why don't our teeth regularly fit in our mouths?Why do women menstruate when so many other mammals don't?Why did humans stand up on two legs in the first place?

    But the president insisted there was nothing to worry about.Fortunately, we are still a nation of skeptics. Fortunately, there are those among us who study pandemics and are willing to look unflinchingly at worst-case scenarios. Michael Lewis’s taut and brilliant nonfiction thriller pits a band of medical visionaries against the wall of ignorance that was the official response of the Trump administration to the outbreak of COVID-19.The characters you will meet in these pages are as fascinating as they are unexpected. A thirteen-year-old girl’s science project on transmission of an airborne pathogen develops into a very grown-up model of disease control. A local public-health officer uses her worm’s-eye view to see what the CDC misses, and reveals great truths about American society. A secret team of dissenting doctors, nicknamed the Wolverines, has everything necessary to fight the pandemic: brilliant backgrounds, world-class labs, prior experience with the pandemic scares of bird flu and swine flu…everything, that is, except official permission to implement their work.Michael Lewis is not shy about calling these people heroes for their refusal to follow directives that they know to be based on misinformation and bad science. Even the internet, as crucial as it is to their exchange of ideas, poses a risk to them. They never know for sure who else might be listening in.