They are promises. They are the only way to walk from one night to the other."Nina Riggs was just thirty-seven years old when initially diagnosed with breast cancer--one small spot. Within a year, the mother of two sons, ages seven and nine, and married sixteen years to her best friend, received the devastating news that her cancer was terminal.How does one live each day, "unattached to outcome"? How does one approach the moments, big and small, with both love and honesty?Exploring motherhood, marriage, friendship, and memory, even as she wrestles with the legacy of her great-great-great grandfather, Ralph Waldo Emerson, Nina Riggs's breathtaking memoir continues the urgent conversation that Paul Kalanithi began in his gorgeous When Breath Becomes Air. She asks, what makes a meaningful life when one has limited time?Brilliantly written, disarmingly funny, and deeply moving, The Bright Hour is about how to love all the days, even the bad ones, and it's about the way literature, especially Emerson, and Nina's other muse, Montaigne, can be a balm and a form of prayer. It's a book about looking death squarely in the face and saying "this is what will be."Especially poignant in these uncertain times, The Bright Hour urges us to live well and not lose sight of what makes us human: love, art, music, words.

    By that afternoon, she saw the world—quite literally—upside down. By New Year’s Day, she was unable to form a coherent sentence. And after hours in the ER, days in the hospital, and multiple questions and tests, her doctors informed her that she had had a stroke. For months afterward, Lee outsourced her memories to a journal, taking diligent notes to compensate for the thoughts she could no longer hold on to. It is from these notes that she has constructed this frank and compelling memoir.In a precise and captivating narrative, Lee navigates fearlessly between chronologies, weaving her childhood humiliations and joys together with the story of the early days of her marriage; and then later, in painstaking, painful, and unflinching detail, the account of her stroke and every upset—temporary or permanent—that it caused. Lee illuminates the connection between memory and identity in an honest, meditative, and truly funny manner, utterly devoid of self-pity. And as she recovers, she begins to realize that this unexpected and devastating event has provided a catalyst for coming to terms with her true self—and, in a way, has allowed her to become the person she’s always wanted to be.

    Mankind's battle to stay alive and healthy for as long as possible is our oldest, most universal struggle. With his characteristic wit and vastly informed historical scope, Roy Porter examines the war fought between disease and doctors on the battleground of the flesh from ancient times to the present. He explores the many ingenious ways in which we have attempted to overcome disease through the ages: the changing role of doctors, from ancient healers, apothecaries, and blood-letters to today's professionals; the array of drugs, from Ayurvedic remedies to the launch of Viagra; the advances in surgery, from amputations performed by barbers without anesthetic to today's sophisticated transplants; and the transformation of hospitals from Christian places of convalescence to modern medical powerhouses. Cleverly illustrated with historic line drawings, the chronic ailments of humanity provide vivid anecdotes for Porter's enlightening story of medicine's efforts to prevail over a formidable and ever-changing adversary.

    In the style of his first book, Andy recalls each event from the detailed documentation recorded at the time, each account written in a way that puts the reader right there next to him so that you live the events in real-time, hear the dialogue between paramedics, patient, their loved ones and other healthcare professionals as it would have been, and share in Andy’s thought processes during each of the ten very different situations he encounters.The term ‘The Dark Side’ describes the frontline emergency aspect of the Ambulance Service, since paramedics frequently experience sombre situations. In ‘The Dark Side, Part 2’ you will share in some truly traumatic, tragic and tearful events involving a seemingly vibrant, healthy young patient, a prison inmate, the victims of an horrific car crash, heart attacks, a frightening epileptic fit, the alarming effects of an allergic reaction, and what can happen when under-strain doctors prescribe the wrong medication. But there’s still room for lighthearted moments and a taste of the sometimes dark humour that allows paramedics to continually deal with events most of us would find too horrific. The detail in the descriptions of the care given to each patient on-scene by Andy and his colleagues will have you marvelling at the ability of these healthcare professionals to work at such speed of thought, buying enough time to deliver a patient into the specialist hands of hospital care and often full recovery. Of course there are inevitably also those times when tears of hope turn to tears of despair for loved ones. You cannot feel that pain until it happens to you, but this book will bring you mighty close to it at times.

    Dave Hnida, a family physician from Littleton, Colorado, volunteered to be deployed to Iraq and spent a tour of duty as a battalion surgeon with a combat unit. In 2007, he went back, this time as a trauma chief at one of the busiest Combat Support Hospitals (CSH) during the Surge. In an environment that was nothing less than a modern-day M*A*S*H, the doctors main objective was simple: Get'em in, get'em out. The only CSH staffed by reservists who tended to be older, more-experienced doctors disdainful of authority, the 399th soon became a medevac destination of choice because of its high survival rate, an astounding 98 percent.

    In 1895 her great-great aunt, Pauline Gross, a seamstress in Ann Arbor, Michigan, confided to a pathology professor at the local university that she expected to die young, like so many others in her family. Rather than dismiss her fears, the pathologist chose to enlist Pauline in the careful tracking of those in her family tree who had died of cancer. Pauline's premonition proved true--she died at 46--but because of her efforts, her family (who the pathologist dubbed 'Family G') would become the longest and most detailed cancer genealogy ever studied in the world. A century after Pauline's confession, researchers would identify the genetic mutation responsible for the family's woes. Now known as Lynch syndrome, the genetic condition predisposes its carriers to several types of cancer, including colorectal, endometrial, ovarian and pancreatic. In 2001, as a young mother with two sons and a keen interest in survival, Ami McKay was among the first to be tested for Lynch syndrome. She had a feeling she'd test positive: her mother's side of the family was riddled with early deaths and her own mother was being treated for the disease. When the test proved her fears true, she began living in "an unsettling state between wellness and cancer," and she's been there ever since. Intimate, candid, and probing, her genetic memoir tells a fascinating story, teasing out the many ways to live with the hand you are dealt.

    Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.

    By demystifying the fantasies surrounding cancer, Sontag shows cancer for what it is--just a disease. Cancer, she argues, is not a curse, not a punishment, certainly not an embarrassment and, it is highly curable, if good treatment is followed.Almost a decade later, with the outbreak of a new, stigmatized disease replete with mystifications and punitive metaphors, Sontag wrote a sequel to Illness as Metaphor, extending the argument of the earlier book to the AIDS pandemic.These two essays now published together, Illness as Metaphor and AIDS and Its Metaphors, have been translated into many languages and continue to have an enormous influence on the thinking of medical professionals and, above all, on the lives of many thousands of patients and caregivers.

    Love stories enfold her, with her husband, her two precious daughters, her enchanting surroundings, but the question she has carried in her heart since childhood—Will I die young?—is threatening all she holds dear, even her sanity. When her young family moves to the US, an answer, a diagnosis, is finally found: she is in the last stages of a fatal congenital heart disease. But is it too late?A young woman risks everything to save her own life in this “unusual, riveting medical drama crafted with deep emotion and exquisite detail” (BookPage).

    But he was alive and trapped inside his own body for ten years.In January 1988 Martin Pistorius, aged twelve, fell inexplicably sick. First he lost his voice and stopped eating. Then he slept constantly and shunned human contact. Doctors were mystified. Within eighteen months he was mute and wheelchair-bound. Martin's parents were told an unknown degenerative disease left him with the mind of a baby and less than two years to live.Martin was moved to care centers for severely disabled children. The stress and heartache shook his parents’ marriage and their family to the core. Their boy was gone. Or so they thought.Ghost Boy is the heart-wrenching story of one boy’s return to life through the power of love and faith. In these pages, readers see a parent’s resilience, the consequences of misdiagnosis, abuse at the hands of cruel caretakers, and the unthinkable duration of Martin’s mental alertness betrayed by his lifeless body.We also see a life reclaimed—a business created, a new love kindled—all from a wheelchair. Martin's emergence from his own darkness invites us to celebrate our own lives and fight for a better life for others.

    One day at the end of 2009, during a routine eye exam that Nora Gallagher nearly skipped, her doctor said, “Darn.” Her right optic nerve was inflamed, the cause unknown, a condition that if left untreated would cause her to lose her sight. And so began her departure from ordinary life and her travels in what she calls Oz, the land of the sick. It looks like the world most of us inhabit, she tells us, except that “the furniture is slightly rearranged”: her friends can’t help her, her trusted doctors don’t know what’s wrong, and what faith she has left just won’t cover it. After a year of searching for a diagnosis and treatment, she arrives at the Mayo Clinic and finds a whole town built around Oz.In the course of her journey, Gallagher encounters inhuman doctors, the modern medical system—in which knowledge takes fifteen years to trickle down—and the strange world that is the famous Mayo Clinic, complete with its grand piano. With unerring candor, and no sentimentality whatsoever, Gallagher describes the unexpected twists and turns of the path she took through a medical mystery and an unfathomably changing life. In doing so, she gives us a singular, luminous map of vulnerability and dark landscapes. “It’s the nature of things to be vulnerable,” Gallagher says. “The disorder is imagining we are not.”

    Vincent DiMaio and veteran crime writer Ron Franscell guide us behind the morgue doors to tell a fascinating life story through the cases that have made Di Maio famous-from the exhumation of assassin Lee Harvey Oswald to the complex issues in the shooting of Florida teenager Trayvon Martin.Beginning with his street-smart Italian origins in Brooklyn, the book spans 40 years of work and more than 9,000 autopsies, and Di Maio's eventual rise into the pantheon of forensic scientists. One of the country's most methodical and intuitive criminal pathologists will dissect himself, maintaining a nearly continuous flow of suspenseful stories, revealing anecdotes, and enough macabre insider details to rivet the most fervent crime fans.

    In a life lasting seventy years, he practiced, taught, and wrote about medicine at Canada's McGill University, America's Johns Hopkins University, and finally as Regius Professor at Oxford. At the time of his death in England in 1919, many considered him to be the greatest doctor in the world. Osler, who was a brilliant, innovative teacher and a scholar of the natural history of disease, revolutionized the art of practicing medicine at the bedside of his patients. He was idolized by two generations of medical students and practitioners for whom he came to personify the ideal doctor. But much more than a physician, Osler was a supremely intelligent humanist. In both his writings and his personal life, and through the prism of the tragedy of the Great War, he embodied the art of living. It was perhaps his legendary compassion that elevated his healing talents to an art form and attracted to his private practice students, colleagues, poets (Walt Whitman for example) politicians, royalty, and nameless ordinary people with extraordinary conditions. William Osler's life lucidly illuminates the times in which he lived. Indeed, this is a book not only about the evolution of modern medicine, the training of doctors, holism in medical thought, and the doctor-patient relationship, but also about humanism, Victorianism, the Great War, and much else. Meticulously researched, drawing on many new sources and offering new interpretations, William Osler: A Life in Medicine brings to life both a fascinating man and the formative age of twentieth-century medicine. It is a classic biography of a classic life, both authoritative and highly readable.

    We all have one, but most of us will never see one. The heart surgeon now has that privilege but, for centuries, the heart was out of reach even for surgeons. So when a surgeon nowadays opens up a ribcage and mends a heart, it remains something of a miracle, even if, to some, it is merely plumbing. As with plumbers, the quality of surgeons’ work varies. As with plumbers, surgeons’ opinion of their own prowess and their own attitude to risk are not always reliable. Measurement is key. We’ve had a century of effective evidence-based medicine. We’ve had barely a decade of thorough monitoring of clinical outcomes. Thanks to the ground-breaking risk modelling of pioneering surgeons like Samer Nashef, we at last know how to judge whether an operation is in a patient’s best interest, which hospital and surgeon would be best for that operation, when it might best be performed and what the exact level of risk is. We have at last made what is important in surgery measurable. But how should surgeons, and their patients, use these newfound insights? Ever since his days as a medical student, Samer Nashef has challenged the medical profession to be more open and more accurate about the success of surgical procedures, for the sake of the patients. In The Naked Surgeon, he unclothes his own profession to demonstrate to his reader (and prospective patient) many revelations, such as the paradox at the heart of the cardiac surgeon’s craft: the more an operation is likely to kill you, the better it is for you. And he does so with absolute clarity, fluency and not a little wit.

    Completely overwhelmed and wrapped in stifling protective suits, he and his team took it in turns to provide care to patients while removing dead bodies from the ward. Against all odds he battled to keep the hospital open, as the queue of sick and dying patients grew every day. Only a few miles down the road the Irish Ambassador and Head of Irish Aid worked relentlessly to rapidly scale up the international response. At a time when entire districts had been quarantined, she travelled around the country, and met with UN agencies, the President and senior ministers so as to be better placed in alerting the world to the catastrophe unfolding in front of her.In this blow-by-blow account, Walsh and Johnson expose the often shocking shortcomings of the humanitarian response to the outbreak, both locally and internationally, and call our attention to the immense courage of those who put their lives on the line every day to contain the disease. Theirs is the definitive account of the fight against an epidemic that shook the world.