Timothy Ferris provides a clear, elegantly written overview of current research and a forecast of where cosmological theory is likely to go in the twenty-first century. He explores the questions that have occurred to even casual readers -- who are curious about nature on the largest scales: What does it mean to say that the universe is "expanding," or that space is "curved"? -- and sheds light on the possibility that our universe is only one among many universes, each with its own physical laws and prospects for the emergence of life.

    This guide answers some of the questions of this complex but endlessly fascinating saga.

    It is more concise and easier to read than some, yet it covers the breadth of emergency medicine practice more comprehensively than others. The bottom line is that I like this book. Just as previous editions did, the seventh presents all of the most pertinent and up-to-date information in a well-organized format that is comprehensive yet easy to read. That and many of the attractive new features in this current edition will ensure its place on my bookshelf for years to come."--JAMAWith 418 contributors representing over 120 medical centers around the world, Tintinalli’s Emergency Medicine is the most practical and clinically rigorous reference of its kind. It covers everything from prehospital care, disaster preparedness, and basic resuscitative techniques, to all the major diseases requiring emergency treatment, such as pulmonary emergencies, renal and GU disorders, and hemophilia. This authoritative, in-depth coverage makes this classic text indispensible not only in emergency departments, but also for residents and practitioners when studying or preparing for any exam they may face.While continuing to provide the most current information for acute conditions, the Seventh Edition of Tintinalli’s Emergency Medicine has been substantially revised and updated to cover all of the conditions for which patients seek emergency department care in a concise and easy-to-read-manner.NEW Features• Full-color design with more figures and tables than ever• Reader-friendly chapter presentation makes it easy to find important material.• Updated tables covering drugs and important clinical information• Patient safety considerations and injury prevention are integrated into chapters, as appropriate• Total revision of the dermatology section enables diagnosis by lesion description and body area affected, and provides current treatment• Organ systems sections reorganized to reflect considerations for actual clinical practice.• New chapters: New adult chapters include Natural Disasters, Aneurysms of the Aorta and Major Arteries; Hip and Knee Pain, Aortic Dissection; Acute Urinary Retention; Subarachnoid Hemorrhage and Intracranial Bleeding; Clotting Disorders; Community –acquired Pneumonia and Noninfectious Pulmonary Infiltrates; Type I Diabetes; Type II Diabetes; Anemia; Tests of Hemostasis; Clotting Disorders; Head Injury in Adults and Children; the Transplant Patient; Grief, Death and Dying; and Legal Issues in Emergency Medicine. Twelve new pediatric chapters including The Diabetic Child, Hematologic-Oncologic Emergencies, Ear and Mastoids, Eye Problems in Infants and Children, Neck Masses, GI Bleeding, Nose and Sinuses, Urologic and Gynecologic Procedures in children, Renal emergencies in children, Behavioral and Psychiatric Disorders in children, Pediatric Procedures, Pediatric ECG Interpretation• Greater coverage of procedures throughout for the most common conditions seen in the emergency department.• Companion DVD features an additional 17 chapters, such as Hyperbaric Oxygen Therapy, Principles of Imaging, Prison Medicine, Military Medicine, The Violent Patient, Forensics, Wound Ballistics, and Drug Interactions.• Companion DVD also features videos and animations for teaching and learning performance of important procedures, especially Ultrasound-Guided Procedures

    For decades after the structure of DNA was identified, scientists focused purely on genes, the regions of the genome that contain codes for the production of proteins. Other regions - 98% of the human genome - were dismissed as 'junk'. But in recent years researchers have discovered that variations in this 'junk' DNA underlie many previously intractable diseases, and they can now generate new approaches to tackling them. Nessa Carey explores, for the first time for a general audience, the incredible story behind a controversy that has generated unusually vituperative public exchanges between scientists. She shows how junk DNA plays an important role in areas as diverse as genetic diseases, viral infections, sex determination in mammals, human biological complexity, disease treatments, even evolution itself - and reveals how we are only now truly unlocking its secrets, more than half a century after Crick and Watson won their Nobel prize for the discovery of the structure of DNA in 1962.

    Since then, Sylvia Nasar's celebrated biography A Beautiful Mind, the basis of a new major motion picture, has revealed the man. The Essential John Nash reveals his work--in his own words. This book presents, for the first time, the full range of Nash's diverse contributions not only to game theory, for which he received the Nobel, but to pure mathematics--from Riemannian geometry and partial differential equations--in which he commands even greater acclaim among academics. Included are nine of Nash's most influential papers, most of them written over the decade beginning in 1949.From 1959 until his astonishing remission three decades later, the man behind the concepts "Nash equilibrium" and "Nash bargaining"--concepts that today pervade not only economics but nuclear strategy and contract talks in major league sports--had lived in the shadow of a condition diagnosed as paranoid schizophrenia. In the introduction to this book, Nasar recounts how Nash had, by the age of thirty, gone from being a wunderkind at Princeton and a rising mathematical star at MIT to the depths of mental illness.In his preface, Harold Kuhn offers personal insights on his longtime friend and colleague; and in introductions to several of Nash's papers, he provides scholarly context. In an afterword, Nash describes his current work, and he discusses an error in one of his papers. A photo essay chronicles Nash's career from his student days in Princeton to the present. Also included are Nash's Nobel citation and autobiography.The Essential John Nash makes it plain why one of Nash's colleagues termed his style of intellectual inquiry as "like lightning striking." All those inspired by Nash's dazzling ideas will welcome this unprecedented opportunity to trace these ideas back to the exceptional mind they came from.

    In their new book, Stephen Hawking and Leonard Mlodinow present the most recent scientific thinking about the mysteries of the universe, in nontechnical language marked by both brilliance and simplicity. In The Grand Design they explain that according to quantum theory, the cosmos does not have just a single existence or history, but rather that every possible history of the universe exists simultaneously. When applied to the universe as a whole, this idea calls into question the very notion of cause and effect. But the “top-down” approach to cosmology that Hawking and Mlodinow describe would say that the fact that the past takes no definite form means that we create history by observing it, rather than that history creates us. The authors further explain that we ourselves are the product of quantum fluctuations in the very early universe, and show how quantum theory predicts the “multiverse”—the idea that ours is just one of many universes that appeared spontaneously out of nothing, each with different laws of nature.Along the way Hawking and Mlodinow question the conventional concept of reality, posing a “model-dependent” theory of reality as the best we can hope to find. And they conclude with a riveting assessment of M-theory, an explanation of the laws governing us and our universe that is currently the only viable candidate for a complete “theory of everything.” If confirmed, they write, it will be the unified theory that Einstein was looking for, and the ultimate triumph of human reason.A succinct, startling, and lavishly illustrated guide to discoveries that are altering our understanding and threatening some of our most cherished belief systems, The Grand Design is a book that will inform—and provoke—like no other.'

    From Beethoven's connection to plumbing to why rotten eggs smell like sulfur, the technical explanations included in this scientific primer tackle 99 chemistry-related questions and provide answers designed to inform and entertain.

    Petr Beckmann holds up this mirror, giving the background of the times when pi made progress -- and also when it did not, because science was being stifled by militarism or religious fanaticism.

    He is regarded by many as the greatest manager ever, building three brilliant sides with players such as Charlton, Edwards, Law & Best. Originally written just two years before Busby's death, this book is now available with a new introduction.

    He has now abandoned his past. Through interviews with Barrett's family and friends, this book provides an account of the man and his illness.

    But are there limits to what we can discover about our physical universe?In this very personal journey to the edges of knowledge, Marcus du Sautoy investigates how leading experts in fields from quantum physics and cosmology, to sensory perception and neuroscience, have articulated the current lie of the land. In doing so, he travels to the very boundaries of understanding, questioning contradictory stories and consulting cutting edge data.Is it possible that we will one day know everything? Or are there fields of research that will always lie beyond the bounds of human comprehension? And if so, how do we cope with living in a universe where there are things that will forever transcend our understanding?In What We Cannot Know, Marcus du Sautoy leads us on a thought-provoking expedition to the furthest reaches of modern science. Prepare to be taken to the edge of knowledge to find out if there’s anything we truly cannot know.

    It provides a simple, thorough survey of elementary topics, starting with set theory and advancing to metric and topological spaces, connectedness, and compactness. 1975 edition.

    Transmitted by body lice, it afflicts the dispossessed—refugees, soldiers, and ghettoized peoples—causing hallucinations, terrible headaches, boiling fever, and often death. The disease plagued the German army on the Eastern Front and left the Reich desperate for a vaccine. For this they turned to the brilliant and eccentric Polish zoologist Rudolf Weigl.In the 1920s, Weigl had created the first typhus vaccine using a method as bold as it was dangerous for its use of living human subjects. The astonishing success of Weigl’s techniques attracted the attention and admiration of the world—giving him cover during the Nazi’s violent occupation of Lviv. His lab soon flourished as a hotbed of resistance. Weigl hired otherwise doomed mathematicians, writers, doctors, and other thinkers, protecting them from atrocity. The team engaged in a sabotage campaign by sending illegal doses of the vaccine into the Polish ghettos while shipping gallons of the weakened serum to the Wehrmacht.Among the scientists saved by Weigl, who was a Christian, was a gifted Jewish immunologist named Ludwik Fleck. Condemned to Buchenwald and pressured to re-create the typhus vaccine under the direction of a sadistic Nazi doctor, Erwin Ding-Schuler, Fleck had to make an awful choice between his scientific ideals or the truth of his conscience. In risking his life to carry out a dramatic subterfuge to vaccinate the camp’s most endangered prisoners, Fleck performed an act of great heroism.Drawing on extensive research and interviews with survivors, Arthur Allen tells the harrowing story of two brave scientists—a Christian and a Jew— who put their expertise to the best possible use, at the highest personal danger.

    Tie Knots unravels the history of ties, the story of the discovery of the new knots and some very elegant mathematics in action. If Einstein had been left alone in Tie Rack for long enough perhaps he would have worked it out : why do people tie their ties in only 4 ways? And how many other possibilities are there? Two Cambridge University physicists, research fellows working from the Cavendish laboratories, have discovered via a recherche branch of mathematics - knot theory - that although only four knots are traditionally used in tying neck ties another 81 exist. This is the story of their discovery, of the history of neck ties and of the equations that express whether a tie is handsome or not. Of the 81 new knots, 6 are practical and elegant. We now have somewhere else to go after the Pratt, the Four-in-Hand, the Full and Half Windsor. Sartorial stylishness is wrapped effortlessly around popular mathematics. A concept developed to describe the movement of gas molecules - the notion of persistent walks around a triangular lattice - also describes the options for tie tying. Pure maths becomes pure fashion in a delightfully designed little package from Fourth Estate.

    He revolutionized the field of topology, which studies properties of geometric configurations that are unchanged by stretching or twisting. The Poincare conjecture lies at the heart of modern geometry and topology, and even pertains to the possible shape of the universe. The conjecture states that there is only one shape possible for a finite universe in which every loop can be contracted to a single point.Poincare's conjecture is one of the seven "millennium problems" that bring a one-million-dollar award for a solution. Grigory Perelman, a Russian mathematician, has offered a proof that is likely to win the Fields Medal, the mathematical equivalent of a Nobel prize, in August 2006. He also will almost certainly share a Clay Institute millennium award.In telling the vibrant story of The Poincare Conjecture, Donal O'Shea makes accessible to general readers for the first time the meaning of the conjecture, and brings alive the field of mathematics and the achievements of generations of mathematicians whose work have led to Perelman's proof of this famous conjecture.