The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    In this beautiful new one-volume edition, modern readers are introduced to one of the best nature writers of the last century. More than one hundred of the original illustrations by Paul Landacre highlight the eloquent and entertaining accounts of American trees. As we read Peattie's descriptions, we catch glimpses of our country's history and past daily life that no textbook could ever illuminate so vividly.Here you'll learn about everything from how a species was discovered to the part it played in our country’s history. Pioneers often stabled an animal in the hollow heart of an old sycamore, and the whole family might live there until they could build a log cabin. The tuliptree, the tallest native hardwood, is easier to work than most softwood trees; Daniel Boone carved a sixty-foot canoe from one tree to carry his family from Kentucky into Spanish territory. In the days before the Revolution, the British and the colonists waged an undeclared war over New England's white pines, which made the best tall masts for fighting ships. It's fascinating to learn about the commercial uses of various woods -- for paper, fine furniture, fence posts, matchsticks, house framing, airplane wings, and dozens of other preplastic uses. But we cannot read this book without the occasional lump in our throats. The American elm was still alive when Peattie wrote, but as we read his account today we can see what caused its demise. Audubon's portrait of a pair of loving passenger pigeons in an American beech is considered by many to be his greatest painting. It certainly touched the poet in Donald Culross Peattie as he depicted the extinction of the passenger pigeon when the beech forest was destroyed. A Natural History of North American Trees gives us a picture of life in America from its earliest days to the middle of the last century. The information is always interesting, though often heartbreaking. While Peattie looks for the better side of man's nature, he reports sorrowfully on the greed and waste that have doomed so much of America's virgin forest.

    The new edition is thoroughly updated, including most notably a new chapter on innate immunity, a capstone chapter on immune responses in time and space, and many new focus boxes drawing attention to exciting clinical, evolutionary, or experimental connections that help bring the material to life.See what's in the LaunchPad

    In clear, lively, warm prose, this edition continues the title's integration of gender, culture, and ethnicity. By the end, readers will learn how to interpret research and to address and resolve controversies. MyPsychLab is an integral part of the Wade/Tavris/Garry program. Engaging activities and assessments provide a teaching and learning system that helps students think like a psychologist. With MyPsychLab, students can watch videos on psychological research and applications, participate in virtual classic experiments, and develop critical thinking skills through writing. "Invitation to Psychology, "5/e is available in a new DSM-5 Updated edition. To learn more, click here. This title is available in a variety of formats - digital and print. Pearson offers its titles on the devices students love through Pearson's MyLab products, CourseSmart, Amazon, and more.

    Written in a concise, bulleted outline format, this well-illustrated text offers 500 USMLE-style review questions, answers, and explanations and features comprehensive content and upgraded USMLE Step 1 information.

    New findings in molecular biology challenge the gene-centered version of Darwinian theory according to which adaptation occurs only through natural selection of chance DNA variations. In Evolution in Four Dimensions, Eva Jablonka and Marion Lamb argue that there is more to heredity than genes. They trace four dimensions in evolution -- four inheritance systems that play a role in evolution: genetic, epigenetic (or non-DNA cellular transmission of traits), behavioral, and symbolic (transmission through language and other forms of symbolic communication). These systems, they argue, can all provide variations on which natural selection can act. Evolution in Four Dimensions offers a richer, more complex view of evolution than the gene-based, one-dimensional view held by many today. The new synthesis advanced by Jablonka and Lamb makes clear that induced and acquired changes also play a role in evolution. After discussing each of the four inheritance systems in detail, Jablonka and Lamb put Humpty Dumpty together again by showing how all of these systems interact. They consider how each may have originated and guided evolutionary history and they discuss the social and philosophical implications of the four-dimensional view of evolution. Each chapter ends with a dialogue in which the authors engage the contrarieties of the fictional (and skeptical) I.M., or Ifcha Mistabra -- Aramaic for the opposite conjecture -- refining their arguments against I.M.'s vigorous counterarguments. The lucid and accessible text is accompanied by artist-physician Anna Zeligowski's lively drawings, which humorously and effectively illustrate the authors' points.

    The beginning chapters introduce basic chemical and biological concepts to provide students with the framework they need to comprehend physiological principles. The chapters that follow promote conceptual understanding rather than rote memorization of facts. Health applications are included throughout the book to heighten interest, deepen understanding of physiological concepts, and help students relate the material to their individual career goals. Every effort has been made to help students integrate related concepts and understand the relationships between anatomical structures and their functions.

    Written By Two Of Today'S Most Respected Computer Science Educators, Nell Dale And John Lewis, The Text Provides A Broad Overview Of The Many Aspects Of The Discipline From A Generic View Point. Separate Program Language Chapters Are Available As Bundle Items For Those Instructors Who Would Like To Explore A Particular Programming Language With Their Students. The Many Layers Of Computing Are Thoroughly Explained Beginning With The Information Layer, Working Through The Hardware, Programming, Operating Systems, Application, And Communication Layers, And Ending With A Discussion On The Limitations Of Computing. Perfect For Introductory Computing And Computer Science Courses, Computer Science Illuminated, Third Edition's Thorough Presentation Of Computing Systems Provides Computer Science Majors With A Solid Foundation For Further Study, And Offers Non-Majors A Comprehensive And Complete Introduction To Computing.

    They attracted followers ranging from Thomas Jefferson, who laid out mastodon bones on the White House floor, to twentieth-century doctors who used their knowledge of new species to conquer epidemic diseases. Acclaimed science writer Richard Conniff brings these daredevil "species seekers" to vivid life. Alongside their globe-spanning tales of adventure, he recounts some of the most dramatic shifts in the history of human thought. At the start, everyone accepted that the Earth had been created for our benefit. We weren't sure where vegetable ended and animal began, we couldn't classify species, and we didn't understand the causes of disease. But all that changed as the species seekers introduced us to the pantheon of life on Earth—and our place within it.

    Hundreds of 3D images take you through each of the body's systems, from skeleton and muscles to the skin and nails. Discover how every aspect of the body functions, how the heart beats, how we breathe, and how the body defends itself. Find out what can go wrong, with descriptions of the ways in which common disorders affect the body's systems.

    Sherwin Nuland, “a gifted and deeply intelligent writer” (San Francisco Chronicle), combines knowledge, compassion, and elegance of expression to shed light on the workings of our bodies from the perspective of a surgeon. Dr. Nuland recounts age-old legends about the functions and "personalities" of the body's organs and, in riveting vignettes of the surgery he has performed, he describes the connections between myth and reality. A brilliant blend of science and folklore, The Mysteries Within reveals the enigmas not only of the body but also of the human imagination.

    

    The Fifth Edition features updated information throughout, including new theories and models such as the Healthy Action Process Approach (HAPA) and the Community Readiness Model (CRM), sections on grant writing and preparing a budget, real-life examples of marketing principles and processes, and a new classification system for evaluation approaches and designs. Health Education, Health Promotion, Health Educators, and Program Planning, Models for Program Planning in Health Promotion, Starting the Planning Process, Assessing Needs, Measurement, Measures, Measurement Instruments and Sampling, Mission Statement, Goals, and Objectives, Theories and Models Commonly Used for Health Promotion Interventions, Interventions, Community Organizing and Community Building, Identification and Allocation of Resources, Marketing: Making Sure Programs Respond to Wants and Needs of Consumers, Implementation: Strategies and Associated Concerns, Evaluation: An Overview, Evaluation Approaches and Designs, Data Analysis and Reporting. Intended for those interested in learning the basics of planning, implementing, and evaluating health promotion programs

    Lanza has teamed with Bob Berman, the most widely read astronomer in the world, to produce Biocentrism, a revolutionary new view of the universe.Every now and then a simple yet radical idea shakes the very foundations of knowledge. The startling discovery that the world was not flat challenged and ultimately changed the way people perceived themselves and their relationship with the world. For most humans of the 15th century, the notion of Earth as ball of rock was nonsense. The whole of Western, natural philosophy is undergoing a sea change again, increasingly being forced upon us by the experimental findings of quantum theory, and at the same time, towards doubt and uncertainty in the physical explanations of the universe’s genesis and structure. Biocentrism completes this shift in worldview, turning the planet upside down again with the revolutionary view that life creates the universe instead of the other way around.In this paradigm, life is not an accidental byproduct of the laws of physics. Biocentrism takes the reader on a seemingly improbable but ultimately inescapable journey through a foreign universe—our own—from the viewpoints of an acclaimed biologist and a leading astronomer. Switching perspective from physics to biology unlocks the cages in which Western science has unwittingly managed to confine itself. Biocentrism will shatter the reader’s ideas of life—time and space, and even death. At the same time it will release us from the dull worldview of life being merely the activity of an admixture of carbon and a few other elements; it suggests the exhilarating possibility that life is fundamentally immortal.The 21st century is predicted to be the Century of Biology, a shift from the previous century dominated by physics. It seems fitting, then, to begin the century by turning the universe outside-in and unifying the foundations of science with a simple idea discovered by one of the leading life-scientists of our age. Biocentrism awakens in readers a new sense of possibility, and is full of so many shocking new perspectives that the reader will never see reality the same way again.

    Genes are important, but only as part of a process constrained by environment, physical laws, and the universal tendencies of complex adaptive systems. In a new preface for this edition, Goodwin reflects on the advances in both genetics and the sciences of complexity since the book's original publication.