Ancestors in Our Genome: The New Science of Human Evolution


Eugene E. Harris - 2014
    Since then, we have sequenced the full genomes of a number of mankind's primate relatives at a remarkable rate. The genomes of the common chimpanzee(2005) and bonobo (2012), orangutan (2011), gorilla (2012), and macaque monkey (2007) have already been identified, and the determination of other primate genomes is well underway. Researchers are beginning to unravel our full genomic history, comparing it with closely related species to answerage-old questions about how and when we evolved. For the first time, we are finding our own ancestors in our genome and are thereby gleaning new information about our evolutionary past.In Ancestors in Our Genome, molecular anthropologist Eugene E. Harris presents us with a complete and up-to-date account of the evolution of the human genome and our species. Written from the perspective of population genetics, and in simple terms, the book traces human origins back to their sourceamong our earliest human ancestors, and explains many of the most intriguing questions that genome scientists are currently working to answer. For example, what does the high level of discordance among the gene trees of humans and the African great apes tell us about our respective separations fromour common ancestor? Was our separation from the apes fast or slow, and when and why did it occur? Where, when, and how did our modern species evolve? How do we search across genomes to find the genomic underpinnings of our large and complex brains and language abilities? How can we find the genomicbases for life at high altitudes, for lactose tolerance, resistance to disease, and for our different skin pigmentations? How and when did we interbreed with Neandertals and the recently discovered ancient Denisovans of Asia? Harris draws upon extensive experience researching primate evolution inorder to deliver a lively and thorough history of human evolution. Ancestors in Our Genome is the most complete discussion of our current understanding of the human genome available.

Allies and Enemies: How the World Depends on Bacteria


Anne E. Maczulak - 2010
    No other living things combine their elegant simplicity with their incredibly complex role: Bacteria keep us alive, supply our food, and regulate our biosphere. We can't live a day without them, and no chemical, antibiotic, or irradiation has ever successfully eradicated them. They're our partners, like it or not--even though some of them will happily kill us. Allies and Enemies tells the story of this amazing, intimate partnership. Authored by Anne Maczulak, a microbiologist who's hunted and worked with an extraordinary array of bacteria, this book offers a powerful new perspective on Earth's oldest creatures. You'll discover how bacteria work, how they evolve, their surprising contributions and uses, the roles they've played in human history, and why you can't survive without them. No form of life is more important, and in Maczulak's hands, none is more fascinating. Outlasted, outnumbered, outsmarted They've been here four billion years--and they even outnumber you in your own body How bacteria keep you alive... ...and how to keep them from killing you "Humans Defeat Germs!" But not for long... The Invisible Universe The stunning hidden relationships between bacteria and the rest of nature

Cartoon Guide to Genetics


Larry Gonick - 1983
    Have you ever asked yourself:Are spliced genes the same as mended Levis?Watson and Crick? Aren't they a team of British detectives?Plant sex? Can they do that?Is Genetic Mutation the name of one of those heavy metal bands?Asparagine? Which of the four food groups is that in?Then you need The Cartoon Guide to Genetics to explain the important concepts of classical and modern genetics—it's not only educational, it's funny too!

The Story of the Human Body: Evolution, Health, and Disease


Daniel E. Lieberman - 2013
    Lieberman illuminates how these ongoing changes have brought many benefits, but also have created novel conditions to which our bodies are not entirely adapted, resulting in a growing incidence of obesity and new but avoidable diseases, including type-2 diabetes. He proposes that many of these chronic illnesses persist and in some cases are intensifying because of "dysevolution," a pernicious dynamic whereby only the symptoms rather than the causes of these maladies are treated. And finally—provocatively—he advocates the use of evolutionary information to help nudge, push, and sometimes oblige us to create a more salubrious environment.(With charts and line drawings throughout.)From the Hardcover edition.

The Deeper Genome: Why There Is More to the Human Genome Than Meets the Eye


John Parrington - 2015
    But things didn't turn out that way. For a start, we turned out to have far fewer genes than originally thought - just over 20,000, the same sort of number as a fruit fly or worm. What's more, the proportionof DNA consisting of genes coding for proteins was a mere 2%. So, was the rest of the genome accumulated 'junk'?Things have changed since those early heady days of the Human Genome Project. But the emerging picture is if anything far more exciting. In this book, John Parrington explains the key features that are coming to light - some, such as the results of the international ENCODE programme, still much debated and controversial in their scope. He gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact ofits 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes ofNeanderthals as well as that of chimps about the development our species. We are learning more about ourselves, and about the genetic aspects of many diseases. But in its complexity, flexibility, and ability to respond to environmental cues, the human genome is proving to be far more subtle than we ever imagined.

Microcosmos: Four Billion Years of Microbial Evolution


Lynn Margulis - 1986
    Margulis to create a vivid new picture of the world that is crucial to our understanding of the future of the planet. Addressed to general readers, the book provides a beautifully written view of evolution as a process based on interdependency and the interconnectedness of all life on the planet.

Why Zebras Don't Get Ulcers


Robert M. Sapolsky - 1993
    Sapolsky's acclaimed and successful Why Zebras Don't Get Ulcers features new chapters on how stress affects sleep and addiction, as well as new insights into anxiety and personality disorder and the impact of spirituality on managing stress.As Sapolsky explains, most of us do not lie awake at night worrying about whether we have leprosy or malaria. Instead, the diseases we fear--and the ones that plague us now--are illnesses brought on by the slow accumulation of damage, such as heart disease and cancer. When we worry or experience stress, our body turns on the same physiological responses that an animal's does, but we do not resolve conflict in the same way--through fighting or fleeing. Over time, this activation of a stress response makes us sick.

At the Bench: A Laboratory Navigator, Updated Edition: A Laboratory Navigator


Kathy Barker - 1998
    In this newly revised edition, chapters have been rewritten to accommodate the impact of computer technology and the Internet, not only on the acquisition and analysis of data, but also on its organization and presentation. Alternatives to the use of radiation have been expanded, and figures and illustrations have been redrawn to reflect changes in laboratory equipment and procedures.

Why is the Penis Shaped Like That?: And Other Reflections on Being Human


Jesse Bering - 2010
    Exploring the history of cannibalism, the neurology of people who are sexually attracted to animals, the evolution of human body fluids, the science of homosexuality, and serious questions about life and death, Bering astutely covers a generous expanse of our kaleidoscope of quirks and origins.With his characteristic irreverence and trademark cheekiness, Bering leaves no topic unturned or curiosity unexamined, and he does it all with an audaciously original voice. Whether you're interested in the psychological history behind the many facets of sexual desire or the evolutionary patterns that have dictated our current mystique and phallic physique, Why Is the Penis Shaped Like That? is bound to create lively discussion and debate for years to come.

Direction & Quality of Light: Your Key to Better Portrait Photography Anywhere


Neil van Niekerk - 2013
    Acclaimed photographer Neil van Niekirk presents seven distinctly different lighting scenarios—available light, exposure metering, a touch of flash, bounced on-camera flash, off-camera flash, video light, and hard sunlight—to show readers how to manipulate the direction and quality of light, the subject’s and photographer’s position, and numerous other variables so as to turn a bad image into a stunning, professional-level portrait. Packed with dozens of instructional, full-color photos, this work also features 10 sample photo sessions, allowing readers the opportunity to see the seven lighting scenarios put to practice.

The Music of Life: Biology Beyond Genes


Denis Noble - 2006
    But in The Music of Life, world renowned physiologist Denis Noble argues that, to truly understand life, we must look beyondthe selfish gene to consider life on a much wider variety of levels. Life, Noble asserts, is a kind of music, a symphonic interplay between genes, cells, organs, body, and environment. He weaves this musical metaphor throughout this personal and deeply lyrical work, illuminating ideas that might otherwise be daunting to non-scientists. In elegant prose, Noblesets out a cutting-edge alternative to the gene's eye view, offering a radical switch of perception in which genes are seen as prisoners and the organism itself is a complex system of many interacting levels. In his more expansive view, life emerges as a process, the ebb and flow of activity in anintricate web of connections. He introduces readers to the realm of systems biology, a field that has been growing in strength in the past decade. Noble, himself one of the founders of this field, argues modern systems biology may be the view we need to adopt to gain a deeper understanding of thenature of life. Drawing on his experiences in his research on the heartbeat, and on evolutionary biology, development, medicine, philosophy, linguistics, and Chinese culture, Noble presents us with a profound and very modern reflection on the nature of life.

Here Is a Human Being: At the Dawn of Personal Genomics


Misha Angrist - 2010
    Unlocking the secrets of our genomes opens the door to understanding why we are the way we are and potentially fixing what ails us, from cancer and diabetes to obesity and male pattern baldness. But what exactly will happen to this information? Will it be a boon or just another marketing tool?Here Is a Human Being is the first in-depth look at personal genomics—its larger-than-life research subjects; its entrepreneurs and do-it-yourselfers; its technology developers; and the bewildered physicians and regulators who must negotiate with it—and what it means to be a “public genome” in a world where privacy is already under siege.

The Lucifer Principle: A Scientific Expedition into the Forces of History


Howard Bloom - 1995
    The Lucifer Priciple is a revolutionary work that explores the intricate relationships among genetics, human behavior, and culture to put forth the thesis that “evil” is a by-product of nature’s strategies for creation and that it is woven into our most basic biological fabric.

The Book of Barely Imagined Beings: A 21st Century Bestiary


Caspar Henderson - 2012
    Ranging from the depths of the ocean to the most arid corners of the land, Caspar Henderson captures the beauty and bizzareness of the many living forms we thought we knew and some we could never have contemplated, inviting us to better imagine the precarious world we inhabit.A witty, vivid blend of cutting edge natural history and meditative reflections, The Book of Barely Imagined Beings is infectious and celebratory about the sheer ingenuity and variety of life.

Who We Are and How We Got Here: Ancient DNA and the New Science of the Human Past


David Reich - 2018
    Now, in The New Science of the Human Past, Reich describes just how the human genome provides not only all the information that a fertilized human egg needs to develop but also contains within it the history of our species. He delineates how the Genomic Revolution and ancient DNA are transforming our understanding of our own lineage as modern humans; how genomics deconstructs the idea that there are no biologically meaningful differences among human populations (though without adherence to pernicious racist hierarchies); and how DNA studies reveal the deep history of human inequality--among different populations, between the sexes, and among individuals within a population.