Two scientists explore the potential of a revolutionary genetics technology capable of easily and affordably manipulating DNA in human embryos to prevent specific diseases, addressing key concerns about related ethical and societal repercussions.

    But by itself, DNA is just an inert blueprint for life. It is the ribosome--an enormous molecular machine made up of a million atoms--that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.

    Unlike their human counterparts, who must alter their environment to accommodate our physical limitations, animals are adaptable to an amazing range of conditions--i.e., radical changes in a creature's physiology take place to match the demands of the environment. Winter provides an especially remarkable situation, because of how drastically it affects the most elemental component of all life: water.Examining everything from food sources in the extremely barren winter landscape to the chemical composition that allows certain creatures to survive, Heinrich's Winter World awakens the largely undiscovered mysteries by which nature sustains herself through the harsh, cruel exigencies of winters

    In What Is Life?, he takes up the challenge of describing what it means to be alive in a way that every reader can understand.It is a shared journey of discovery; step-by-step Nurse illuminates five great ideas that underpin biology—the Cell, the Gene, Evolution by Natural Selection, Life as Chemistry, and Life as Information. He introduces the scientists who made the most important advances, and, using his personal experiences in and out of the lab, he shares with us the challenges, the lucky breaks, and the thrilling eureka moments of discovery.Nurse writes with delight at life’s richness and with a sense of the urgent role of biology in our time. To survive the challenges that face us all today—climate change, pandemic, loss of biodiversity and food security—it is vital that we all understand what life is.

    But almost everything about it, from the elements that forged stars, planets, and lifeforms, to the fundamental forces of physics, can be traced back to what happened in just the first three minutes of its life.In this book, Nobel Laureate Steven Weinberg describes in wonderful detail what happened in these first three minutes. It is an exhilarating journey that begins with the Planck Epoch - the earliest period of time in the history of the universe - and goes through Einstein's Theory of Relativity, the Hubble Red Shift, and the detection of the Cosmic Microwave Background. These incredible discoveries all form the foundation for what we now understand as the "standard model" of the origin of the universe. The First Three Minutes examines not only what this model looks like, but also tells the exciting story of the bold thinkers who put it together.Clearly and accessibly written, The First Three Minutes is a modern-day classic, an unsurpassed explanation of where it is we really come from.

    She is perhaps the best known and most studied fossil hominid of the twentieth century, the benchmark by which other discoveries of human ancestors are judged.”–From Lucy’s LegacyIn his New York Times bestseller, Lucy: The Beginnings of Humankind, renowned paleoanthropologist Donald Johanson told the incredible story of his discovery of a partial female skeleton that revolutionized the study of human origins. Lucy literally changed our understanding of our world and who we come from. Since that dramatic find in 1974, there has been heated debate and–most important–more groundbreaking discoveries that have further transformed our understanding of when and how humans evolved. In Lucy’s Legacy, Johanson takes readers on a fascinating tour of the last three decades of study–the most exciting period of paleoanthropologic investigation thus far. In that time, Johanson and his colleagues have uncovered a total of 363 specimens of Australopithecus afarensis (Lucy’s species, a transitional creature between apes and humans), spanning 400,000 years. As a result, we now have a unique fossil record of one branch of our family tree–that family being humanity–a tree that is believed to date back a staggering 7 million years.Focusing on dramatic new fossil finds and breakthrough advances in DNA research, Johanson provides the latest answers that post-Lucy paleoanthropologists are finding to questions such as: How did Homo sapiens evolve? When and where did our species originate? What separates hominids from the apes? What was the nature of Neandertal and modern human encounters? What mysteries about human evolution remain to be solved?Donald Johanson is a passionate guide on an extraordinary journey from the ancient landscape of Hadar, Ethiopia–where Lucy was unearthed and where many other exciting fossil discoveries have since been made–to a seaside cave in South Africa that once sheltered early members of our own species, and many other significant sites. Thirty-five years after Lucy, Johanson continues to enthusiastically probe the origins of our species and what it means to be human.

    The planet most like ours, it has still been thought impossible to reach, let alone explore and inhabit.Now with the advent of a revolutionary new plan, all this has changed. leading space exploration authority Robert Zubrin has crafted a daring new blueprint, Mars Direct, presented here with illustrations, photographs, and engaging anecdotes.The Case for Mars is not a vision for the far future or one that will cost us impossible billions. It explains step-by-step how we can use present-day technology to send humans to Mars within ten years; actually produce fuel and oxygen on the planet's surface with Martian natural resources; how we can build bases and settlements; and how we can one day "terraform" Mars--a process that can alter the atmosphere of planets and pave the way for sustainable life.

    As she grows into adulthood, only a few of her eggs mature, are released into the oviduct, and are fertilized by sperm stored from copulation that took place days or weeks earlier. Within a matter of hours, the fragile yolk is surrounded by albumen and the whole is gradually encased within a turquoise jewel of a shell. Soon afterward the fully formed egg is expelled onto a bare rocky ledge, where it will be incubated for four weeks before another chick emerges and the life cycle begins again. The Most Perfect Thing is about how eggs in general are made, fertilized, developed, and hatched. The eggs of most birds spend just 24 hours in the oviduct; however, that journey takes 48 hours in cuckoos, which surreptitiously lay their eggs in the nests of other birds. From the earliest times, the study of birds' ovaries and ova (eggs) played a vital role in the quest to unravel the mysteries of fertilization and embryo development in humans. Birkhead uses birds' eggs as wondrous portals into natural history, enlivened by the stories of naturalists and scientists, including Birkhead and his students, whose discoveries have advanced current scientific knowledge of reproduction.

    Tameness is the key trait in the domestication of cats, dogs, horses, cows, and other mammals, from rats to reindeer. Surprisingly, with selection for tameness comes a suite of seemingly unrelated alterations, including floppy ears, skeletal and coloration changes, and sex differences. It’s a package deal known as the domestication syndrome, elements of which are also found in humans. Our highly social nature—one of the keys to our evolutionary success—is due to our own tameness. In Domesticated, Richard C. Francis weaves history and anthropology with cutting-edge ideas in genomics and evo devo to tell the story of how we domesticated the world, and ourselves in the process.

    Why We Get Sick compels readers to reexamine the age-old attitudes toward sickness. Line drawings.

    For twenty years, Mark Hertsgaard has investigated global warming for outlets including theNew Yorker, NPR, Time, Vanity Fair, and The Nation. But the full truth did not hit home until he became a father and, soon thereafter, learned that climate change had already arrived―a century earlier than forecast―with impacts bound to worsen for decades to come. Hertsgaard's daughter Chiara, now five years old, is part of what he has dubbed "Generation Hot" -- the two billion young people worldwide who will spend the rest of their lives coping with mounting climate disruption. HOT is a father's cry against climate change, but most of the book focuses on solutions, offering a deeply reported blueprint for how all of us―as parents, communities, companies and countries―can navigate this unavoidable new era. Combining reporting from across the nation and around the world with personal reflections on his daughter’s future, Hertsgaard provides "pictures" of what is expected over the next fifty years: Chicago’s climate transformed to resemble Houston’s; dwindling water supplies and crop yields at home and abroad; the redesign of New York and other cities against mega-storms and sea-level rise. Above all, he shows who is taking wise, creative precautions. For in the end, HOT is a book about how we’ll survive.

    From Edward Lorenz’s discovery of the Butterfly Effect, to Mitchell Feigenbaum’s calculation of a universal constant, to Benoit Mandelbrot’s concept of fractals, which created a new geometry of nature, Gleick’s engaging narrative focuses on the key figures whose genius converged to chart an innovative direction for science. In Chaos, Gleick makes the story of chaos theory not only fascinating but also accessible to beginners, and opens our eyes to a surprising new view of the universe.

    Through a series of entertaining, bite-sized chapters that combine anthropological insight with cutting-edge science, we gain fresh perspectives into our first hominin ancestors and ways to challenge perceptions about the traditional progression of evolution. With Lee as our guide, we discover that we indeed have always been a species of continuous change.

    He also found the notes Darwin kept throughout Annie's illness, the eulogy he delivered at her funeral—and provocative new insights into Darwin’s views on nature, evolution, and the human condition. In Darwin, His Daughter & Human Evolution, Keynes shows that Darwin was not "a cold intellect with no place for love in his famous 'struggle for existence,' [but]...a man of uncommon warmth" (Scientific American).Creation: The True Story of Charles Darwin is now a major motion picture and the movie tie-in paperback is also available from Riverhead Books.

    After World War II, it reshaped the global order-whoever could master uranium could master the world. Marie Curie gave us hope that uranium would be a miracle panacea, but the Manhattan Project gave us reason to believe that civilization would end with apocalypse. Slave labor camps in Africa and Eastern Europe were built around mine shafts and America would knowingly send more than six hundred uranium miners to their graves in the name of national security. Fortunes have been made from this yellow dirt; massive energy grids have been run from it. Fear of it panicked the American people into supporting a questionable war with Iraq and its specter threatens to create another conflict in Iran. Now, some are hoping it can help avoid a global warming catastrophe. In "Uranium," Tom Zoellner takes readers around the globe in this intriguing look at the mineral that can sustain life or destroy it.