But things didn't turn out that way. For a start, we turned out to have far fewer genes than originally thought - just over 20,000, the same sort of number as a fruit fly or worm. What's more, the proportionof DNA consisting of genes coding for proteins was a mere 2%. So, was the rest of the genome accumulated 'junk'?Things have changed since those early heady days of the Human Genome Project. But the emerging picture is if anything far more exciting. In this book, John Parrington explains the key features that are coming to light - some, such as the results of the international ENCODE programme, still much debated and controversial in their scope. He gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact ofits 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes ofNeanderthals as well as that of chimps about the development our species. We are learning more about ourselves, and about the genetic aspects of many diseases. But in its complexity, flexibility, and ability to respond to environmental cues, the human genome is proving to be far more subtle than we ever imagined.

    Communication is also emphasized, with a focus on how to document and communicate project developments, both within and outside of the team. In-depth coverage of planning, scheduling and cost management is also provided. The authors' goal is to provide many cases that are fun and elicit interesting debates, and this edition includes new end-of-chapter cases. In addition, all new up-to-date Real World Project Management vignettes are included at the beginning and within each chapter, giving you a taste of how project management is practically applied in the workplace. Key points of each chapter are highlighted in Critical Success Factor boxes, providing an overview of the main ideas covered within the chapter. End-of-chapter materials contain questions and Internet exercises that allow you to apply the concepts covered in the chapter. Sprinkled throughout each chapter are boxed questions designed to test your comprehension of key concepts. A trial version of Microsoft Office Project 2007 is included for student use on class projects.

    Written in a concise, bulleted outline format, this well-illustrated text offers 500 USMLE-style review questions, answers, and explanations and features comprehensive content and upgraded USMLE Step 1 information.

    This distinctive text was developed to stand apart from all other A&P texts with unparalleled art, a writing style that has been acclaimed by both users and reviewers and clinical coverage that offers the perfect balance without being too much. Saladin's well-accepted organization of topics is based upon the most logical physiological ties between body systems. This text requires no prior knowledge of college chemistry or cell biology, and is designed for a two-semester A&P college course.

    Turn to any page, and you'll find essential point-of-care guidance on all the major conditions seen in clinical medicine. Completely updated to reflect all the major advances and new clinical developments, the new edition of the Manual is the most indispensable yet. It continues to focus on diagnosis and therapy with an emphasis on patient care and offers authoritative, high-yield coverage of: Etiology and epidemiology Clinically relevant pathophysiology Signs & Symptoms o Differential Diagnosis Physical and Laboratory Findings Therapeutics o Practice GuidelinesNEW FEATURESFull-color presentation for the first time!Full-color images of clinical conditions encountered in dermatology, cardiology, and eye diseases New chapters on end-of-life care, congenital heart disease in the adult patient, non-invasive cardiac examination, and metabolic syndromeLook for these other great Harrison's titles:Harrison's Principles of Internal Medicine, 17eHarrison's Online available through Accessmedicine.com

    Readers will continue to enjoy the current, concise, and straightforward approach to the field that made previous editions so popular. They'll understand the experimental observations that underlie the science of immunology at the molecular, cellular, and whole organism level-and explore the conclusions that can be drawn from those observations.The smart way to study!Elsevier titles with STUDENT CONSULT will help you master difficult concepts and study more efficiently in print and online! Perform rapid searches. Integrate bonus content from other disciplines. Download text to your handheld device. And a lot more. Each STUDENT CONSULT title comes with full text online, a unique image library, case studies, USMLE style questions, and online note-taking to enhance your learning experience.Highlights the implications of immunologic science for the management of human disease.Features over 365 full-color illustrations that highlight important processes and concepts, and bring the three-dimensional structures of molecules to life. Offers a wealth of reader-friendly features including major concepts highlighted in bold italics - at-a-glance boxes that present specialized information and explanations of current technological approaches - a wealth of tables that summarize key information - a glossary of terms - a CD Molecule Appendix that reflects the latest properties of known CD Molecules - an appendix on immunologic laboratory techniques - and more.Includes free access to a full-text online version, a downloadable collection of full-color images, sophisticated immunologic animations, integration links to bonus content in other STUDENT CONSULT titles, content clipping for handhelds, and more - all through the STUDENT CONSULT website at www.studentconsult.com.Incorporates the newest understandings of basic science as well as the newest research findings.Includes new information on the organization of lymphoid organs and mechanisms of innate immunity.Presents enhanced, more straightforward explanations of subjects such as of antigen-presenting cells and the biology of T cell activation.

    "The London, Upton, Stone series has helped over 1,000,000 photography students capture their potential. After a very successful first edition, this second edition returns with the most up-to-date industry knowledge. Modeled after the long-running and widely used "A ""Short Course in Photography, " a brief text which presents the medium entirely in its most updated form.

    Jack H. Wilmore, Dr. David Costill, W. Larry Kenney

    Topics covered in the book include linear equations, ratios, quadratic equations, special factorizations, complex numbers, graphing linear and quadratic equations, linear and quadratic inequalities, functions, polynomials, exponents and logarithms, absolute value, sequences and series, and much more!The text is structured to inspire the reader to explore and develop new ideas. Each section starts with problems, giving the student a chance to solve them without help before proceeding. The text then includes solutions to these problems, through which algebraic techniques are taught. Important facts and powerful problem solving approaches are highlighted throughout the text. In addition to the instructional material, the book contains well over 1000 problems.This book can serve as a complete Algebra I course, and also includes many concepts covered in Algebra II. Middle school students preparing for MATHCOUNTS, high school students preparing for the AMC, and other students seeking to master the fundamentals of algebra will find this book an instrumental part of their mathematics libraries.656About the author: Richard Rusczyk is a co-author of Art of Problem Solving, Volumes 1 and 2, the author of Art of Problem Solving's Introduction to Geometry. He was a national MATHCOUNTS participant, a USA Math Olympiad winner, and is currently director of the USA Mathematical Talent Search.

    The book also provides a balanced presentation of time-varying and static fields, preparingstudents for employment in today's industrial and manufacturing sectors. Streamlined to facilitate student understanding, this edition features worked examples in every chapter that explain how to use the theory presented in the text to solve different kinds of problems. Numerical methods, including MATLAB and vector analysis, are also included to help students analyzesituations that they are likely to encounter in industry practice. Elements of Electromagnetics, Fifth Edition, is designed for introductory undergraduate courses in electromagnetics.

    Fundamentals of Biostatistics with CD-Rom.

    For the new edition, the dissection guide has been separated from thetext and remodeled to make it more distinctive and easier to read, and the text itself has been greatly expanded, with new sections on embryology, organogenesis, congenital malformations of clinical significance, and the new imaging and diagnostic techniques such as CT scanning. With an expandedgeneral introduction and additional explanations throughout, the new edition will prove the best Manual ever, answering the needs of a wide array of students and courses.

    For introductory courses in computer concepts or computer literacy often including instruction in Microsoft Office.A Computer Concepts Text Focused on Today’s Student!Technology in Action engages students by combining a unique teaching approach with rich companion media.

    Full of advice on how surgeons should use their heads as well as their hands - how to think, plan, and improvise - when, for example, operating on a massively bleeding trauma patient. Starts with general principles, continues with specific injuries to abdomen, chest, neck, and peripheral vessels. Generously illustrated throughout, with drawings produced specifically for this book. For residents, general surgeons with an interest in trauma, and for surgeons operating on badly wounded patients in isolated military, rural, or humanitarian settings. Asher Hirshberg and Kenneth L Mattox are trauma surgeons at the Ben Taub General Hospital, Houston, and professors at the Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, USA. Kenneth L Maddox is famous as the lead editor of McGraw Hill's classic text, Trauma, now in its fifth edition. This is going to be a GREAT book!