Bottle of Lies: The Inside Story of the Generic Drug Boom
Katherine Eban - 2019
Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
The Master and His Emissary: The Divided Brain and the Making of the Western World
Iain McGilchrist - 2009
In a book of unprecedented scope, McGilchrist draws on a vast body of recent brain research, illustrated with case histories, to reveal that the difference is profound—not just this or that function, but two whole, coherent, but incompatible ways of experiencing the world. The left hemisphere is detail oriented, prefers mechanisms to living things & is inclined to self-interest. The right hemisphere has greater breadth, flexibility & generosity. This division helps explain the origins of music & language, & casts new light on the history of philosophy, as well as on some mental illnesses. The 2nd part of the book takes a journey thru the history of Western culture, illustrating the tension between these two worlds as revealed in the thought & belief of thinkers & artists, from Aeschylus to Magritte. He argues that, despite its inferior grasp of reality, the left hemisphere is increasingly taking precedence in the modern world, with potentially disastrous consequences.List of IllustrationsAcknowledgmentsIntroductionAsymmetry and the brain --What do the two hemispheres 'do'? --Language, truth and music --The nature of the two worlds --The primacy of the right hemisphere --The triumph of the left hemisphere --Imitation and the evolution of culture --The ancient world --The Renaissance and the Reformation --The Enlightenment --Romanticism and the Industrial Revolution --The modern and post-modern worldsConclusionNotes BibliographyIndex
How Emotions Are Made: The Secret Life of the Brain
Lisa Feldman Barrett - 2016
Scientists have long supported this assumption by claiming that emotions are hardwired in the body or the brain. Today, however, the science of emotion is in the midst of a revolution on par with the discovery of relativity in physics and natural selection in biology—ans this paradigm shift has far-reaching implications for us all.Leading the charge is psychologist and neuroscientist Lisa Feldman Barrett, whose theory of emotion is driving a deeper understanding of the mind and brain, and shedding new light on what it means to be human. Her research overturns the widely held belief that emotions are housed in different parts of the brain and are universally expressed and recognized. Instead, she has shown that emotion is constructed in the moment, by core systems that interact across the whole brain, aided by a lifetime of learning. This new theory means that you play a much greater role in your emotional life than you ever thought. Its repercussions are already shaking the foundations not only of psychology but also of medicine, the legal system, child-rearing, meditation, and even airport security.Why do emotions feel automatic? Does rational thought really control emotion? How does emotion affect disease? How can you make your children more emotionally intelligent? How Emotions Are Made answers these questions and many more, revealing the latest research and intriguing practical applications of the new science of emotion, mind, and brain.
The Science of Fear: Why We Fear the Things We Shouldn't--and Put Ourselves in Greater Danger
Daniel Gardner - 2008
And yet, we are the safest and healthiest humans in history. Irrational fear seems to be taking over, often with tragic results. For example, in the months after 9/11, when people decided to drive instead of fly—believing they were avoiding risk—road deaths rose by more than 1,500. In this fascinating, lucid, and thoroughly entertaining examination of how humans process risk, journalist Dan Gardner had the exclusive cooperation of Paul Slovic, the world renowned risk-science pioneer, as he reveals how our hunter gatherer brains struggle to make sense of a world utterly unlike the one that made them. Filled with illuminating real world examples, interviews with experts, and fast-paced, lean storytelling, The Science of Fear shows why it is truer than ever that the worst thing we have to fear is fear itself.
Post Corona: From Crisis to Opportunity
Scott Galloway - 2020
Some businesses--like home exercise company Peloton, video conference software maker Zoom, and Amazon--woke up to find themselves crushed under an avalanche of consumer demand. Others--like the restaurant, travel, hospitality, and live entertainment industries--scrambled to escape obliteration.But as Scott Galloway argues, the pandemic has not been a change agent so much as an accelerant of trends already well underway. In Post Corona, he outlines the contours of the crisis and the opportunities that lie ahead. Some businesses, like the powerful tech monopolies, will thrive as a result of the disruption. Other industries, like higher education, will struggle to maintain a value proposition that no longer makes sense when we can't stand shoulder to shoulder. And the pandemic has accelerated deeper trends in government and society, exposing a widening gap between our vision of America as a land of opportunity, and the troubling realities of our declining wellbeing.Combining his signature humor and brash style with sharp business insights and the occasional dose of righteous anger, Galloway offers both warning and hope in equal measure. As he writes, Our commonwealth didn't just happen, it was shaped. We chose this path--no trend is permanent and can't be made worse or corrected.
Surgery, The Ultimate Placebo: A Surgeon Cuts through the Evidence
Ian Harris - 2016
In this book you will see how commonly performed operations can be found to be useless or even harmful when properly evaluated. That these claims come from an experienced, practicing orthopedic surgeon who performs many of these operations himself, makes the unsettling argument particularly compelling. Of course no surgeon is recommending invasive surgery in bad faith, but Ian Harris argues that the evidence for the success for many common operations, including knee arthroscopies, back fusion or cardiac stenting, become current accepted practice without full examination of the evidence.
Barking Up the Wrong Tree: The Surprising Science Behind Why Everything You Know About Success Is (Mostly) Wrong
Eric Barker - 2017
In Barking Up the Wrong Tree, Eric Barker reveals the extraordinary science behind what actually determines success and most importantly, how anyone can achieve it. You’ll learn:• Why valedictorians rarely become millionaires, and how your biggest weakness might actually be your greatest strength • Whether nice guys finish last and why the best lessons about cooperation come from gang members, pirates, and serial killers• Why trying to increase confidence fails and how Buddhist philosophy holds a superior solution• The secret ingredient to “grit” that Navy SEALs and disaster survivors leverage to keep going• How to find work-life balance using the strategy of Genghis Khan, the errors of Albert Einstein, and a little lesson from Spider-ManBy looking at what separates the extremely successful from the rest of us, we learn what we can do to be more like them—and find out in some cases why it’s good that we aren’t. Barking Up the Wrong Tree draws on startling statistics and surprising anecdotes to help you understand what works and what doesn’t so you can stop guessing at success and start living the life you want.
Doing Harm: The Truth About How Bad Medicine and Lazy Science Leave Women Dismissed, Misdiagnosed, and Sick
Maya Dusenbery - 2018
In addition to offering a clear-eyed explanation of the root causes of this insidious and entrenched bias and laying out its effects, she suggests concrete steps we can take to cure it.
Younger Next Year for Women
Chris Crowley - 2004
And because you’re already more attuned to your physical and emotional needs, and more inclined to commit to a healthier lifestyle, you're poised to live brilliantly for the thirty-plus years after menopause. All you need now is the program outlined in Younger Next Year for Women—which, for starters, will help you avoid literally 70 percent of the decay and eliminate 50 percent of the injuries and illnesses associated with getting older. How? Drawn from disciplines as varied as evolutionary biology, cell physiology, experimental psychology and anthropology, the science behind Younger Next Year is clear. Our bodies are programmed to do one of two things: either grow or decay. Sitting in front of a screen all day tells the body to decay. Taking a walk or doing yoga tells the body to grow. Loneliness and stress trigger decay; love and laughter trigger growth. Just as clear as the science is the goal: Become the active gatekeeper of your own body and gain the power to control those signals of growth and decay. Seven simple rules show the way, from #1 Exercise six days a week for the rest of your life, to #6 Care, to #7 Connect and commit. They’re called Harry’s Rules, named for the doctor and coauthor—Henry S. Lodge, M.D.—who formulated them, and who explains the precise science behind each one. But since it’s one thing to know something’s good for you and quite another to put it into practice, Dr. Lodge, the scientist, is joined by Chris Crowley—coauthor, exhorter and living example—whose brusque charm and infectious enthusiasm will actually have you living by the rules. So, congratulations. You’re now about to get younger.
Radical Evolution: The Promise and Peril of Enhancing Our Minds, Our Bodies — And What it Means to Be Human
Joel Garreau - 2005
As you read this, we are engineering the next stage of human evolution. Through advances in genetic, robotic, information and nanotechnologies, we are altering our minds, our memories, our metabolisms, our personalities, our progeny - and perhaps our very souls.Taking us behind the scenes with today's foremost researchers and pioneers, Garreau reveals that the super powers of our comic-book heroes already exist, or are in development in hospitals, labs, and research facilities around the country -- from the revved up reflexes and speed of Spider-Man and Superman, to the enhanced mental acuity and memory capabilities of an advanced species. Over the next fifteen years, Garreau makes clear, these enhancements will become part of our everyday lives. Where will they lead us? To heaven - where technology's promise to make us smarter, vanquish illness and extend our lives is the answer to our prayers? Or will they lead us, as some argue, to hell - where unrestrained technology brings about the ultimate destruction of our entire species? With the help and insights of the gifted thinkers and scientists who are making what has previously been thought of as science fiction a reality, Garreau explores how these developments, in our lifetime, will affect everything from the way we date to the way we work, from how we think and act to how we fall in love. It is a book about what our world is becoming today, not fifty years out. As Garreau cautions, it is only by anticipating the future that we can hope to shape it.
The Extended Mind: The Power of Thinking Outside the Brain
Annie Murphy Paul - 2021
That’s what we tell ourselves when facing a tricky problem or a difficult project. But a growing body of research indicates that we’ve got it exactly backwards. What we need to do, says acclaimed science writer Annie Murphy Paul, is think outside the brain. A host of “extra-neural” resources—the feelings and movements of our bodies, the physical spaces in which we learn and work, and the minds of those around us— can help us focus more intently, comprehend more deeply, and create more imaginatively. The Extended Mind outlines the research behind this exciting new vision of human ability, exploring the findings of neuroscientists, cognitive scientists, psychologists, and examining the practices of educators, managers, and leaders who are already reaping the benefits of thinking outside the brain. She excavates the untold history of how artists, scientists, and authors—from Jackson Pollock to Jonas Salk to Robert Caro—have used mental extensions to solve problems, make discoveries, and create new works. In the tradition of Howard Gardner’s Frames of Mind or Daniel Goleman’s Emotional Intelligence, The Extended Mind offers a dramatic new view of how our minds work, full of practical advice on how we can all think better.
Overdiagnosed: Making People Sick in the Pursuit of Health
H. Gilbert Welch - 2011
Gilbert WelchRead Overdiagnosed: Making People Sick in the Pursuit of Health PDF from Beacon Press,H. Gilbert WelchDownload H. Gilbert Welch's PDF E-book Overdiagnosed: Making People Sick in the Pursuit of Health
The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline
Dale E. Bredesen - 2017
Revealing that AD is not one condition, as it is currently treated, but three, The End of Alzheimer's outlines 36 metabolic factors (micronutrients, hormone levels, sleep) that can trigger "downsizing" in the brain. The protocol shows us how to rebalance these factors using lifestyle modifications like taking B12, eliminating gluten, or improving oral hygiene.The results are impressive. Of the first ten patients on the protocol, nine displayed significant improvement with 3-6 months; since then the protocol has yielded similar results with hundreds more. Now, The End of Alzheimer's brings new hope to a broad audience of patients, caregivers, physicians, and treatment centers with a fascinating look inside the science and a complete step-by-step plan that fundamentally changes how we treat and even think about AD.
How Not to Die: Surprising Lessons on Living Longer, Safer, and Healthier from America's Favorite Medical Examiner
Jan Garavaglia - 2008
What is particularly sad about this is that many of these deaths could easily have been prevented. Although Dr. Garavaglia, or Dr. G, as she’s known to many, could not tell these individuals how to avoid their fates, we can benefit from her experience and profound insight into the choices we make each day.In How Not to Die, Dr. G acts as a medical detective to identify the often-unintentional ways we harm our bodies, then shows us how to use that information to live better and smarter. She provides startling tips on how to make wise choices so that we don’t have to see her, or someone like her, for a good, long time. • In “Highway to the Morgue,” we learn the one commonsense safety tip that can prevent deadly accidents—and the reason you should never drive with the windows half open• “Code Blue” teaches us how to increase our chances of leaving the hospital alive—and how to insist that everyone caring for you practice the easiest hygiene method around• “Everyday Dangers” informs us why neat freaks live longer—and the best ways to stay safe in a car during a lightning stormUsing anecdotes from her cases and a liberal dose of humor, Dr. G gives us her prescription for living a healthier, better, longer life—and unlike many doctors’ orders, this one is surprisingly easy to follow.
A First-Rate Madness: Uncovering the Links Between Leadership and Mental Illness
S. Nassir Ghaemi - 2011
By combining analysis of the historical evidence with the latest psychiatric research, Ghaemi demonstrates how he thinks these qualities have produced brilliant leadership under the toughest circumstances.individuals and society at large-however high the price for those who endure these illnesses.