Lisa Sanders, author of the monthly New York Times Magazine column "Diagnosis," the inspiration for the hit Fox TV series House, M.D.The experience of being ill can be like waking up in a foreign country. Life, as you formerly knew it, is on hold while you travel through this other world as unknown as it is unexpected. When I see patients in the hospital or in my office who are suddenly, surprisingly ill, what they really want to know is, ‘What is wrong with me?’ They want a road map that will help them manage their new surroundings. The ability to give this unnerving and unfamiliar place a name, to know it–on some level–restores a measure of control, independent of whether or not that diagnosis comes attached to a cure. Because, even today, a diagnosis is frequently all a good doctor has to offer.A healthy young man suddenly loses his memory–making him unable to remember the events of each passing hour. Two patients diagnosed with Lyme disease improve after antibiotic treatment–only to have their symptoms mysteriously return. A young woman lies dying in the ICU–bleeding, jaundiced, incoherent–and none of her doctors know what is killing her. In Every Patient Tells a Story, Dr. Lisa Sanders takes us bedside to witness the process of solving these and other diagnostic dilemmas, providing a firsthand account of the expertise and intuition that lead a doctor to make the right diagnosis.Never in human history have doctors had the knowledge, the tools, and the skills that they have today to diagnose illness and disease. And yet mistakes are made, diagnoses missed, symptoms or tests misunderstood. In this high-tech world of modern medicine, Sanders shows us that knowledge, while essential, is not sufficient to unravel the complexities of illness. She presents an unflinching look inside the detective story that marks nearly every illness–the diagnosis–revealing the combination of uncertainty and intrigue that doctors face when confronting patients who are sick or dying. Through dramatic stories of patients with baffling symptoms, Sanders portrays the absolute necessity and surprising difficulties of getting the patient’s story, the challenges of the physical exam, the pitfalls of doctor-to-doctor communication, the vagaries of tests, and the near calamity of diagnostic errors. In Every Patient Tells a Story, Dr. Sanders chronicles the real-life drama of doctors solving these difficult medical mysteries that not only illustrate the art and science of diagnosis, but often save the patients’ lives.

    Perception is the foundation of human experience, but few of us understand why we see what we do, much less how. By revealing the startling truths about the brain and its perceptions, Beau Lotto shows that the next big innovation is not a new technology: it is a new way of seeing. In his first major book, Lotto draws on over two decades of pioneering research to explain that our brain didn't evolve to see the world accurately. It can't! Visually stunning, with entertaining illustrations and optical illusions throughout, and with clear and comprehensive explanations of the science behind how our perceptions operate, Deviate will revolutionize the way you see yourself, others and the world. With this new understanding of how the brain functions, Deviate is not just an illuminating account of the neuroscience of thought, behavior, and creativity: it is a call to action, enlisting readers in their own journey of self-discovery.

    From one of the world's leading neuroscientists comes a deeply engaging trip into the depths of the human mind.In The Secret Life of the Mind, neuroscientist Mariano Sigman offers a grand yet concise survey of everything you ever wanted to know about how the mind works.From research showing that, even as infants, we are able to form notions of mathematics, language, and morality, to how years and years of formal and informal education can fundamentally change our brains and how we experience the world, The Secret Life of the Mind is an accessible and fascinating overview of neuroscience that will help readers begin to understand even the smallest things that make us who we are.Personal, surprising, and delightfully illuminating, The Secret Life of the Mind is an intimate look into our most intimate selves.

    But through her formidable memory and determination, she made her way to graduate school, where she chanced upon research that inspired her to invent cognitive exercises to "fix" her brain. Now the Director of Arrowsmith School, the author interweaves her personal tale with riveting case histories from her more than 30 years of working with both children and adults to restructure their own brains.The Woman Who Changed Her Brain powerfully and poignantly illustrates how the lives of children and adults struggling with learning disorders can be dramatically transformed. This remarkable book by a brilliant pathbreaker deepens our understanding of how the brain works and of the brain’s profound impact on how we participate in the world. Our brains shape us, but this book offers clear and hopeful evidence of the corollary: we can shape our brains.

    In The Invisible Gorilla, Christopher Chabris and Daniel Simons, creators of one of psychology’s most famous experiments, use remarkable stories and counterintuitive scientific findings to demonstrate an important truth: Our minds don’t work the way we think they do. We think we see ourselves and the world as they really are, but we’re actually missing a whole lot.Again and again, we think we experience and understand the world as it is, but our thoughts are beset by everyday illusions. We write traffic laws and build criminal cases on the assumption that people will notice when something unusual happens right in front of them. We’re sure we know where we were on 9/11, falsely believing that vivid memories are seared into our minds with perfect fidelity. And as a society, we spend billions on devices to train our brains because we’re continually tempted by the lure of quick fixes and effortless self-improvement.  The Invisible Gorilla reveals the myriad ways that our intuitions can deceive us, but it’s much more than a catalog of human failings. Chabris and Simons explain why we succumb to these everyday illusions and what we can do to inoculate ourselves against their effects. Ultimately, the book provides a kind of x-ray vision into our own minds, making it possible to pierce the veil of illusions that clouds our thoughts and to think clearly for perhaps the first time.

    Ellen J. Langer and her team of researchers at Harvard introduced a unique concept of mindfulness, adapted to contemporary life in the West. Langer's theory has been applied to a wide number of fields, including health, business, aging, social justice, and learning. There is now a new psychological assessment based on her work (called the Langer Mindfulness Scale). In her introduction to this 25th anniversary edition, Dr. Langer (now known as "the Mother of Mindfulness") outlines some of these exciting applications and suggests those still to come.

    They can be euphoric one moment, despairing and depressed the next. There are an estimated 10 million sufferers of BPD living in America today—each displaying remarkably similar symptoms: ● a shaky sense of identity ● sudden violent outbursts ● oversensitivity to real or imagined rejection ● brief, turbulent love affairs ● frequent periods of intense depression ● eating disorders, drug abuse, and other self-destructive tendencies ● an irrational fear of abandonment and an inability to be alone For years BPD was difficult to describe, diagnose, and treat. But now, for the first time, Dr. Jerold J. Kreisman and health writer Hal Straus offer much-needed professional advice, helping victims and their families to understand and cope with this troubling,shockingly widespread affliction.

    Judy Melinek began her training as a New York City forensic pathologist. With her husband T.J. and their toddler Daniel holding down the home front, Judy threw herself into the fascinating world of death investigation, performing autopsies, investigating death scenes, counseling grieving relatives. Working Stiff chronicles Judy's two years of training, taking readers behind the police tape of some of the most harrowing deaths in the Big Apple, including a firsthand account of the events of September 11, the subsequent anthrax bio-terrorism attack, and the disastrous crash of American Airlines flight 587.Lively, action-packed, and loaded with mordant wit, Working Stiff offers a firsthand account of daily life in one of America's most arduous professions, and the unexpected challenges of shuttling between the domains of the living and the dead. The body never lies, and through the murders, accidents, and suicides that land on her table, Dr. Melinek lays bare the truth behind the glamorized depictions of autopsy work on shows like CSI and Law and Order to reveal the secret story of the real morgue.

    But a medical revolution is underway that can solve this problem: Astonishing new research is revealing that the health of your brain is, to an extraordinary degree, dictated by the state of your microbiome - the vast population of organisms that live in your body and outnumber your own cells ten to one. What's taking place in your intestines today is determining your risk for any number of brain-related conditions.In BRAIN MAKER, Dr. Perlmutter explains the potent interplay between intestinal microbes and the brain, describing how the microbiome develops from birth and evolves based on lifestyle choices, how it can become "sick," and how nurturing gut health through a few easy strategies can alter your brain's destiny for the better. With simple dietary recommendations and a highly practical program of six steps to improving gut ecology, BRAIN MAKER opens the door to unprecedented brain health potential.

    And yet, we are the safest and healthiest humans in history. Irrational fear seems to be taking over, often with tragic results. For example, in the months after 9/11, when people decided to drive instead of fly—believing they were avoiding risk—road deaths rose by more than 1,500. In this fascinating, lucid, and thoroughly entertaining examination of how humans process risk, journalist Dan Gardner had the exclusive cooperation of Paul Slovic, the world renowned risk-science pioneer, as he reveals how our hunter gatherer brains struggle to make sense of a world utterly unlike the one that made them. Filled with illuminating real world examples, interviews with experts, and fast-paced, lean storytelling, The Science of Fear shows why it is truer than ever that the worst thing we have to fear is fear itself.

    Schizophrenia is not a single unifying diagnosis, and Esme Weijun Wang writes not just to her fellow members of the "collected schizophrenias" but to those who wish to understand it as well. Opening with the journey toward her diagnosis of schizoaffective disorder, Wang discusses the medical community's own disagreement about labels and procedures for diagnosing those with mental illness, and then follows an arc that examines the manifestations of schizophrenia in her life. In essays that range from using fashion to present as high-functioning to the depths of a rare form of psychosis, and from the failures of the higher education system and the dangers of institutionalisation to the complexity of compounding factors such as PTSD and Lyme disease, Wang's analytical eye, honed as a former lab researcher at Stanford, allows her to balance research with personal narrative. An essay collection of undeniable power, The Collected Schizophrenias dispels misconceptions and provides insight into a condition long misunderstood.

    But treatment for it has not changed much in the last three decades. In the world of psychiatry, time has apparently stood still... until now. In this game-changing book, University of Cambridge Professor Edward Bullmore reveals the breakthrough new science on the link between depression and inflammation of the body and brain. He explains how and why we now know that mental disorders can have their root cause in the immune system, and outlines a future revolution in which treatments could be specifically targeted to break the vicious cycle of stress, inflammation and depression. The Inflamed Mind goes far beyond the clinic and the lab, representing a whole new way of looking at how mind, brain and body all work together in a sometimes misguided effort to help us survive in a hostile world. It offers insights into the story of Western medicine, how we have got it wrong as well as right in the past, and how we could start getting to grips with depression and other mental disorders much more effectively in the future.

     For his groundbreaking sexual research, Alfred Kinsey and his team interviewed 18,000 people, relying on them to honestly report their most intimate experiences. Using the Internet, the neuroscientists Ogas and Gaddam quietly observed the raw sexual behaviors of half a billion people. By combining their observations with neuroscience and animal research, these two young neuroscientists finally answer the long-disputed question: what do people really like? Ogas and Gaddam's findings are transforming the way scientists and therapists think about sexual desire. In their startling book, Ogas and Gaddam analyze a "billion wicked thoughts" on the Internet: a billion Web searches, a million individual search histories, a million erotic stories, a half-million erotic videos, a million Web sites, millions of online personal ads, and many other enormous sources of sexual data in order to understand the true differences between male and female desires, including: ?Men and women have hardwired sexual cues analogous to our hardwired tastes-there are sexual versions of sweet, sour, salty, savory, and bitter. But men and women are wired with different sets of cues. ?The male sexual brain resembles a reckless hunter, while the female sexual brain resembles a cautious detective agency. ?Men form their sexual interests during adolescence and rarely change. Women's sexual interests are plastic and change frequently. ?The male sexual brain is an "or gate": A single stimulus can arouse it. The female sexual brain is an "and gate": It requires many simultaneous stimuli to arouse it. ?When it comes to sexual arousal, men prefer overweight women to underweight women, and a significant number of men seek out erotic images of women in their 40s, 50s, and 60s. ?Women enjoy writing and sharing erotic stories with other women. The fastest growing genre of erotic stories for women are stories about two heterosexual men having sex. ?Though the male sexual brain is much more different from the female sexual brain than is commonly believed, the sexual brain of gay men is virtually identical to that of straight men. Featuring cutting-edge, jaw-dropping science, this wildly entertaining and controversial book helps readers understand their partner's sexual desires with a depth of knowledge unavailable from any other source. Its fascinating and occasionally disturbing findings will rock our modern understanding of sexuality, just as Kinsey's reports did sixty years ago.

    But what is Prozac—a medication, or a mental steroid? A cure for depression, or a drug that changes personality? Reported to turn shy people into social butterflies and to improve work performance, memory, even dexterity, does Prozac work on character rather than illness? Are you using it "cosmetically," to make people more attractive? More energetic, more socially acceptable? And what does it tell us about the nature of character and the mutability of self?

    She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.