It is the story of two nurses who witnessed the early years of the HIV/AIDS epidemic from the frontline. It focuses on their lives and their experiences. Some of the story is raw, sometimes graphic, but familiar for people with HIV infection, family members, friends, and other nurses and medical professionals such as Ellen and Valery. There were hundreds of nurses who went through what Ellen and Valery experienced. They want to tell this story to give a voice to a generation lost, encouraging the world to remember one simple thing: this history cannot be repeated.

    Beautifully presented, it introduces the formation and function of blood cells and diseases that arise from dysfunction and disruption of these processes. Basic science, diagnostic tests and clinical features and management are all easily explained. The 5th edition has been reorganized to increase the focus on discrete disorders to show the increased understanding of the causation of blood disorders and improved diagnostic techniques and clinical management. A new standardized approach to describing disease and management has also been introduced. The authors' engaging style and inviting presentation continue to make Essential Haematology the perfect learning and reference text.Fully supported with downloadable figures from the book, along with a PDF of the captions, at www.wiley.com/go/essentialhaematology

     What is it like to be the senior surgeon when a young woman is brought to casualty with a life-threatening bleed? What does the fear of cancer do to a person? Is it ever best not to tell the patient everything? Tender is the Scalpel’s Edge draws on Gautam Das’s real-life experiences working in Britain’s busy NHS hospitals, from the plunging depths of a patient dying on the operating table to the euphoria of a life saved by teamwork and skill. Described in exquisite detail and with extreme sensitivity, Gautam shares his journey from a medical student fighting his own inner demons to a senior NHS consultant surgeon. Shards of his earlier life in India add to the richness of the narrative in tales that observe life with all its contradictions, like the little village boy with bone cancer. While other anecdotes take in the lighter side of life, Tender is the Scalpel’s Edge is written to inform and engross the general reader, as well as those with a curiosity of life behind the surgeon’s mask. Written in a manner similar to other medical biographies including Henry Marsh’s Do No Harm, Atul Gawande’s Being Mortal and When Breath Becomes Air by Paul Kalanithi, Tender is the Scalpel’s Edge is a moving collection of true stories from a professional at the frontline of medical care.

    We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise.So we've all heard of genes, but how do they actually work?According to legend, Ernest Hemingway was once given a six-toed cat by an old sea captain, and her distinctive descendants still roam the writer's Florida estate today. Scientists now know that the fault driving this profusion of digits lies in a tiny genetic control switch, miles away (in molecular terms) from the gene that 'makes' toes. And it's the same mistake that gives rise to multi-toed humans too.There are 2.2 metres of DNA inside every one of your cells, encoding roughly 20,000 genes. These are the 'recipes' that tell our cells how to make the building blocks of life, along with myriad control switches ensuring they're turned on and off at the right time and in the right place. But rather than a static string of genetic code, this is a dynamic, writhing biological library. And figuring out how it all works – how your genes make you, you – is a major challenge for researchers around the world.Drawing on stories ranging from six-toed cats and stickleback hips to wobbly worms and zombie genes, geneticist Kat Arney explores the how our genes work, creating a companion reader to the book of life itself.

    A lyrical journey from hope to despair and back again, The First Cell explores cancer from every angle: medical, scientific, cultural, and personal. Indeed, Raza describes how she bore the terrible burden of being her own husband's oncologist as he succumbed to leukemia. Like When Breath Becomes Air, The First Cell is no ordinary book of medicine, but a book of wisdom and grace by an author who has devoted her life to making the unbearable easier to bear.

    You'll experience the rush of adrenaline and the pain of loss. You'll go beyond the lights and sirens to witness the instinct of intelligence, the courage and commitment that makes the EMT an unsung hero in one of the most vital and compelling medical dramas of our time.

    It is written by internationally recognized Harvard Medical School faculty and select medical students, and is the best text to bridge basic physiology with clinical care of patients.This edition provides updated coverage of pathogenesis of atherosclerosis, pathophysiology of acute coronary syndromes, mechanisms of heart failure, molecular mechanisms of dysrhythmias, the genomic basis of cardiomyopathies and congenital heart disease, and pharmacology. Numerous new illustrations are included.A companion Website on thePoint will include animations and audio heart sounds.

    Daniel Mierlak, a psychiatrist for twenty-five years, on a journey to the stranger corners of human experience. Here you’ll meet: Tony, chauffeur to the fabulously rich, who overcomes crippling anxiety only to find himself descend into a homicidal rage following a botched cosmetic procedure. Amanda, hospitalized for mania, who sees a change to her medicine as an assassination attempt, and then stalks her doctor for a year after discharge. James, a schizophrenic hearing voices telling him to kill himself, whose piano playing leads to a shocking secret about his past. Psychiatric treatment is normally a private encounter and often misunderstood. In describing twelve of his most challenging cases, Dr. Mierlak brings you into his sessions, into his patients’ lives, and into the world of psychiatry. Get ready for some surprises.

    It started the revolution in patients working with their doctors and using humor to boost their bodies' capacity for healing. When Norman Cousins was diagnosed with a crippling and irreversible disease, he forged an unusual collaboration with his physician, and together they were able to beat the odds. The doctor's genius was in helping his patient to use his own powers: laughter, courage, and tenacity. The patient's talent was in mobilizing his body's own natural resources, proving what an effective healing tool the mind can be. This remarkable story of the triumph of the human spirit is truly inspirational reading.

    In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. In England, cows attack their owners in the milking parlors, while in the American West, thousands of deer starve to death in fields full of grass.What these strange conditions–including fatal familial insomnia, kuru, scrapie, and mad cow disease–share is their cause: prions. Prions are ordinary proteins that sometimes go wrong, resulting in neurological illnesses that are always fatal. Even more mysterious and frightening, prions are almost impossible to destroy because they are not alive and have no DNA–and the diseases they bring are now spreading around the world.In The Family That Couldn’t Sleep, essayist and journalist D. T. Max tells the spellbinding story of the prion’s hidden past and deadly future

    Award-winning author Jonathan Edlow, M.D., shows the doctor as detective and the epidemiologist as elite sleuth in stories that are as gripping as the best thrillers.In these stories a notorious stomach bug turns a suburban dinner party into a disaster that almost claims its host; a diminutive woman routinely eats more than her football-playing boyfriend but continually loses weight; a young executive is diagnosed with lung cancer, yet the tumors seem to wax and wane inexplicably. Written for the lay person who wishes to better grasp how doctors decipher the myriad clues and puzzling symptoms they often encounter, each story presents a very different case where doctors must work to find the accurate diagnosis before it is too late. Edlow uses his unique ability to relate complex medical concepts in a writing style that is clear, engaging and easily understandable. The resulting stories both entertain us and teach us much about medicine, its history and the subtle interactions among pathogens, humans, and the environment.

    Of the top ten killers, it is the only disease for which there is no cure or treatment. For most people, there is nothing that they can do to fight back. But one family is doing all they can. The DeMoe family has the most devastating form of the disease that there is: early onset Alzheimer’s, an inherited genetic mutation that causes the disease in 100 percent of cases, and has a 50 percent chance of being passed onto the next generation. Of the six DeMoe children whose father had it, five have inherited the gene; the sixth, Karla, has inherited responsibility for all of them. But rather than give up in the face of such news, the DeMoes have agreed to spend their precious, abbreviated years as part of a worldwide study that could utterly change the landscape of Alzheimer’s research and offers the brightest hope for future treatments—and possibly a cure. Drawing from several years of in-depth research with this charming and upbeat family, journalist Niki Kapsambelis tells the story of Alzheimer’s through the humanizing lens of these ordinary people made extraordinary by both their terrible circumstances and their bravery. Their tale is intertwined with the dramatic narrative history of the disease, the cutting-edge research that brings us ever closer to a possible cure, and the accounts of the extraordinary doctors spearheading these groundbreaking studies. From the oil fields of North Dakota to the jungles of Colombia, this incredible narrative redefines courage in the face of one of the most pervasive and mysterious pandemics of our time.

    We know her today primarily as a saintly character, perhaps as a heroic reformer of Britain’s health-care system. The reality is more involved and far more fascinating. In an utterly beguiling narrative that reads like the best Victorian fiction, acclaimed author Gillian Gill tells the story of this richly complex woman and her extraordinary family.Born to an adoring wealthy, cultivated father and a mother whose conventional facade concealed a surprisingly unfettered intelligence, Florence was connected by kinship or friendship to the cream of Victorian England’s intellectual aristocracy. Though moving in a world of ease and privilege, the Nightingales came from solidly middle-class stock with deep traditions of hard work, natural curiosity, and moral clarity. So it should have come as no surprise to William Edward and Fanny Nightingale when their younger daughter, Florence, showed an early passion for helping others combined with a precocious bent for power. Far more problematic was Florence’s inexplicable refusal to marry the well-connected Richard Monckton Milnes. As Gill so brilliantly shows, this matrimonial refusal was at once an act of religious dedication and a cry for her freedom–as a woman and as a leader. Florence’s later insistence on traveling to the Crimea at the height of war to tend to wounded soldiers was all but incendiary–especially for her older sister, Parthenope, whose frustration at being in the shade of her more charismatic sibling often led to illness. Florence succeeded beyond her wildest dreams. But at the height of her celebrity, at the age of thirty-seven, she retired to her bedroom and remained there for most of the rest of her life, allowing visitors only by appointment.Combining biography, politics, social history, and consummate storytelling, Nightingales is a dazzling portrait of an amazing woman, her difficult but loving family, and the high Victorian era they so perfectly epitomized. Beautifully written, witty, and irresistible, Nightingales is truly a tour de force.From the Hardcover edition.

    

    Charting his 15 years working as a GP, from rookie to becoming a partner in one of the UK's busiest surgeries, Dr Amir Khan's stories are as much about community and care as they are about blood tests and bodily fluids. Along the way, he introduces us to the patients that have taught him about love, loss and family - from the regulars to the rarities - giving him the most unbelievable highs and crushing lows, and often in just 10 minutes. There is the unsuspecting pregnant woman about to give birth at the surgery; the man offering to drop his trousers and take a urine sample there and then; the family who needs support through bereavement, the vulnerable child who will need continuing care for a long-term health condition; and, of course, the onset of COVID-19 that tested the surgery at every twist and turn. But, it's all in a day's work for Amir. The Doctor Will See You Now is a powerful story of hope, love and compassion, but it's also a rare insider account of what really goes on behind those surgery doors.