One day he was a doctor treating the dying, and the next he was a patient struggling to live. And just like that, the future he and his wife had imagined evaporated. When Breath Becomes Air chronicles Kalanithi's transformation from a naïve medical student "possessed," as he wrote, "by the question of what, given that all organisms die, makes a virtuous and meaningful life" into a neurosurgeon at Stanford working in the brain, the most critical place for human identity, and finally into a patient and new father confronting his own mortality. What makes life worth living in the face of death? What do you do when the future, no longer a ladder toward your goals in life, flattens out into a perpetual present? What does it mean to have a child, to nurture a new life as another fades away? These are some of the questions Kalanithi wrestles with in this profoundly moving, exquisitely observed memoir. Paul Kalanithi died in March 2015, while working on this book, yet his words live on as a guide and a gift to us all. "I began to realize that coming face to face with my own mortality, in a sense, had changed nothing and everything," he wrote. "Seven words from Samuel Beckett began to repeat in my head: 'I can't go on. I'll go on.'" When Breath Becomes Air is an unforgettable, life-affirming reflection on the challenge of facing death and on the relationship between doctor and patient, from a brilliant writer who became both.

    In The Ego Tunnel, philosopher Thomas Metzinger claims otherwise: No such thing as a self exists. The conscious self is the content of a model created by our brain—an internal image, but one we cannot experience as an image. Everything we experience is “a virtual self in a virtual reality.”But if the self is not “real,” why and how did it evolve? How does the brain construct it? Do we still have souls, free will, personal autonomy, or moral accountability? In a time when the science of cognition is becoming as controversial as evolution, The Ego Tunnel provides a stunningly original take on the mystery of the mind.

    But when a new admission to the critical care unit almost died his first night on call, he found himself scrambling. Visions of mastery quickly gave way to hopes of simply surviving hospital life, where confidence was hard to come by and no amount of med school training could dispel the terror of facing actual patients.This funny, candid memoir of McCarthy’s intern year at a New York hospital provides a scorchingly frank look at how doctors are made, taking readers into patients’ rooms and doctors’ conferences to witness a physician's journey from ineptitude to competence. McCarthy's one stroke of luck paired him with a brilliant second-year adviser he called “Baio” (owing to his resemblance to the Charles in Charge star), who proved to be a remarkable teacher with a wicked sense of humor. McCarthy would learn even more from the people he cared for, including a man named Benny, who was living in the hospital for months at a time awaiting a heart transplant. But no teacher could help McCarthy when an accident put his own health at risk, and showed him all too painfully the thin line between doctor and patient.The Real Doctor Will See You Shortly offers a window on to hospital life that dispenses with sanctimony and self-seriousness while emphasizing the black-comic paradox of becoming a doctor: How do you learn to save lives in a job where there is no practice?

    This engaging book--part scientific overview, part memoir, part futurist speculation--describes Koch's search for an empirical explanation for consciousness. Koch recounts not only the birth of the modern science of consciousness but also the subterranean motivation for his quest--his instinctual (if "romantic") belief that life is meaningful.Koch describes his own groundbreaking work with Francis Crick in the 1990s and 2000s and the gradual emergence of consciousness (once considered a "fringy" subject) as a legitimate topic for scientific investigation. Present at this paradigm shift were Koch and a handful of colleagues, including Ned Block, David Chalmers, Stanislas Dehaene, Giulio Tononi, Wolf Singer, and others. Aiding and abetting it were new techniques to listen in on the activity of individual nerve cells, clinical studies, and brain-imaging technologies that allowed safe and noninvasive study of the human brain in action.Koch gives us stories from the front lines of modern research into the neurobiology of consciousness as well as his own reflections on a variety of topics, including the distinction between attention and awareness, the unconscious, how neurons respond to Homer Simpson, the physics and biology of free will, dogs, Der Ring des Nibelungen, sentient machines, the loss of his belief in a personal God, and sadness. All of them are signposts in the pursuit of his life's work--to uncover the roots of consciousness.

    Over My Head is an inspiring story of how one woman comes to terms with the loss of her identity and the courageous steps (and hilarious missteps) she takes while learning to rebuild her life. The author, a 45-year-old doctor and clinical professor of medicine, describes the aftermath of a brain injury eleven years ago which stripped her of her beloved profession. For years she was deprived of her intellectual companionship and the ability to handle the simplest undertakings like shopping for groceries or sorting the mail. Her progression from confusion, dysfunction, and alienation to a full, happy life is told with restraint, great style, and considerable humor.

    Her encounters with the other students intensify her search for identity. She comes to find fulfilment not in isolation, but through her relationships with others.

    A native Californian, Didion applies her scalpel-like intelligence to the state’s ethic of ruthless self-sufficiency in order to examine that ethic’s often tenuous relationship to reality.Combining history and reportage, memoir and literary criticism, Where I Was From explores California’s romances with land and water; its unacknowledged debts to railroads, aerospace, and big government; the disjunction between its code of individualism and its fetish for prisons. Whether she is writing about her pioneer ancestors or privileged sexual predators, robber barons or writers (not excluding herself), Didion is an unparalleled observer, and her book is at once intellectually provocative and deeply personal.

    Kim Miller is an immaculately put-together woman with a great career, a loving boyfriend, and a beautifully tidy apartment in Brooklyn. You would never guess that she spent her childhood hiding behind the closed doors of her family’s idyllic Long Island house, navigating between teetering stacks of aging newspaper, broken computers, and boxes upon boxes of unused junk festering in every room—the product of her father’s painful and unending struggle with hoarding. In this coming-of-age story, Kim brings to life her experience of growing up in a rat-infested home, concealing her father’s shameful secret from friends for years, and of the emotional burden that ultimately led to an attempt to take her own life. And in beautiful prose, Miller sheds light on her complicated yet loving relationship with her parents that has thrived in spite of the odds. Coming Clean is a story about recognizing where we come from and the relationships that define us—and about finding peace in the homes we make for ourselves.

    Revealing that AD is not one condition, as it is currently treated, but three, The End of Alzheimer's outlines 36 metabolic factors (micronutrients, hormone levels, sleep) that can trigger "downsizing" in the brain. The protocol shows us how to rebalance these factors using lifestyle modifications like taking B12, eliminating gluten, or improving oral hygiene.The results are impressive. Of the first ten patients on the protocol, nine displayed significant improvement with 3-6 months; since then the protocol has yielded similar results with hundreds more. Now, The End of Alzheimer's brings new hope to a broad audience of patients, caregivers, physicians, and treatment centers with a fascinating look inside the science and a complete step-by-step plan that fundamentally changes how we treat and even think about AD.

    But Maurice Hilleman came close. Maurice Hilleman is the father of modern vaccines. Chief among his accomplishments are nine vaccines that practically every child gets, rendering formerly deadly diseases — including mumps, rubella, and measles — nearly forgotten. Author Paul A. Offit's rich and lively narrative details Hilleman's research and experiences as the basis for a larger exploration of the development of vaccines, covering two hundred years of medical history and traveling across the globe in the process. The history of vaccines necessarily brings with it a cautionary message, as they have come under assault from those insisting they do more harm than good. Paul Offit clearly and compellingly rebuts these arguments, and, by demonstrating how much the work of Hilleman and others has gained for humanity, shows us how much we have to lose.

    They are all versions of a bigger question: how do you live? How do you do the good or honourable thing, while flourishing and feeling happy? This question obsessed Renaissance writers, none more than Michel Eyquem de Montaigne (1533-92), perhaps the first truly modern individual. A nobleman, public official, and wine-grower, he wrote free-roaming explorations of his thought and experience, unlike anything written before. He called them 'essays', meaning 'attempts' or 'tries'. Into them he put whatever was in his head: his tastes in wine and food, his childhood memories, the way his dog's ears twitched when dreaming, as well as the appalling events of the religious civil wars raging around him. The Essays was an instant bestseller, and more than four hundred years later, Montaigne's honesty and charm still draw people to him. Readers come to him in search of companionship, wisdom and entertainment--and in search of themselves. This book, a spirited and singular biography (and the first full life of Montaigne in English for nearly fifty years), relates the story of his life by way of the questions he posed and the answers he explored. It traces his bizarre upbringing (made to speak only Latin), youthful career and sexual adventures, travels, and friendships with the scholar and poet Etienne de La Boétie and with his adopted 'daughter', Marie de Gournay. And as we read, we also meet his readers--who for centuries have found in Montaigne an inexhaustible source of answers to the haunting question, 'how to live?'

    Pirsig's Zen & the Art of Motorcycle Maintenance is an examination of how we live, a meditation on how to live better set around the narration of a summer motorcycle trip across America's Northwest, undertaken by a father & his young son.

    Frankl held a series of public lectures in Vienna. The psychiatrist, who would soon become world famous, explained his central thoughts on meaning, resilience, and the importance of embracing life even in the face of great adversity.Published here for the very first time in English, Frankl's words resonate as strongly today--as the world faces a coronavirus pandemic, social isolation, and great economic uncertainty--as they did in 1946. He offers an insightful exploration of the maxim "Live as if you were living for the second time," and he unfolds his basic conviction that every crisis contains opportunity. Despite the unspeakable horrors of the camps, Frankl learned from the strength of his fellow inmates that it is always possible to "say yes to life"--a profound and timeless lesson for us all.

    For no apparent reason, she's singled out from her siblings, blamed for her family's problems and targeted for unspeakable abuse. The loving environment she's come to know becomes an endless nightmare of twisted punishments as she's forced to confront the dark cruelty lurking inside the mother she idolizes. Based on a true story, Call Me Tuesday recounts, with raw emotion, a young girl's physical and mental torment at the mercy of the monster in her mother's clothes--a monster she doesn't know how to stop loving. Tuesday's painful journey through the hidden horrors of child abuse will open your eyes, and her unshakable love for her parents will tug at your heartstrings.

    She has managed to achieve this in spite of being diagnosed as schizophrenic and given a "grave" prognosis—and suffering the effects of her illness throughout her life.Saks was only eight, and living an otherwise idyllic childhood in sunny 1960s Miami, when her first symptoms appeared in the form of obsessions and night terrors. But it was not until she reached Oxford University as a Marshall Scholar that her first full-blown episode, complete with voices in her head and terrifying suicidal fantasies, forced her into a psychiatric hospital.Saks would later attend Yale Law School where one night, during her first term, she had a breakdown that left her singing on the roof of the law school library at midnight. She was taken to the emergency room, force-fed antipsychotic medication, and tied hand-and-foot to the cold metal of a hospital bed. She spent the next five months in a psychiatric ward.So began Saks's long war with her own internal demons and the equally powerful forces of stigma. Today she is a chaired professor of law who researches and writes about the rights of the mentally ill. She is married to a wonderful man.In The Center Cannot Hold, Elyn Saks discusses frankly and movingly the paranoia, the inability to tell imaginary fears from real ones, and the voices in her head insisting she do terrible things, as well as the many obstacles she overcame to become the woman she is today. It is destined to become a classic in the genre.